Job C J Calis

Summary

Publications

  1. doi request reprint Severe anemia in Malawian children
    Job C J Calis
    Malawi Liverpool Wellcome Trust Clinical Research Programme, College of Medicine, Blantyre, Malawi
    N Engl J Med 358:888-99. 2008
  2. pmc Erythropoiesis in HIV-infected and uninfected Malawian children with severe anemia
    Job C J Calis
    Global Child Health Group, Emma Children s Hospital, Academic Medical Center, Amsterdam, The Netherlands
    AIDS 24:2883-7. 2010
  3. pmc Severe anaemia is not associated with HIV-1 env gene characteristics in Malawian children
    Job C J Calis
    Emma Children s Hospital, Academic Medical Centre, Amsterdam, The Netherlands
    BMC Infect Dis 8:26. 2008
  4. pmc Pathophysiological mechanisms of severe anaemia in Malawian children
    Michaël Boele van Hensbroek
    Malawi Liverpool Wellcome Trust Clinical Research Programme, College of Medicine, University of Malawi, Blantyre, Malawi
    PLoS ONE 5:e12589. 2010
  5. ncbi request reprint Second-line HIV Treatment in Ugandan Children: Favorable Outcomes and No Protease Inhibitor Resistance
    Ragna S Boerma
    Amsterdam Institute for Global Health and Development, Department of Global Health, Academic Medical Center of the University of Amsterdam, The Netherlands Global Child Health Group, Emma Children s Hospital, Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands
    J Trop Pediatr . 2016
  6. doi request reprint Conventional and novel peripheral blood iron markers compared against bone marrow in Malawian children
    Femkje A M Jonker
    Global Child Health Group, Emma Children s Hospital, Academic Medical Centre, Amsterdam, The Netherlands
    J Clin Pathol 67:717-23. 2014
  7. pmc Iron status predicts malaria risk in Malawian preschool children
    Femkje A M Jonker
    Global Child Health Group, Emma Children s Hospital, Academic Medical Centre, Amsterdam, The Netherlands
    PLoS ONE 7:e42670. 2012
  8. pmc Low hepcidin levels in severely anemic malawian children with high incidence of infectious diseases and bone marrow iron deficiency
    Femkje A M Jonker
    Global Child Health Group, Emma Children s Hospital, Academic Medical Centre, Amsterdam, The Netherlands
    PLoS ONE 8:e78964. 2013
  9. pmc Long term outcome of severe anaemia in Malawian children
    Kamija S Phiri
    Malawi Liverpool Wellcome Trust Clinical Research Programme, College of Medicine, Blantyre, Malawi
    PLoS ONE 3:e2903. 2008
  10. pmc Real-time PCR demonstrates Ancylostoma duodenale is a key factor in the etiology of severe anemia and iron deficiency in Malawian pre-school children
    Femkje A M Jonker
    Global Child Health Group, Emma Children s Hospital, Academic Medical Centre, Amsterdam, The Netherlands
    PLoS Negl Trop Dis 6:e1555. 2012

Collaborators

Detail Information

Publications15

  1. doi request reprint Severe anemia in Malawian children
    Job C J Calis
    Malawi Liverpool Wellcome Trust Clinical Research Programme, College of Medicine, Blantyre, Malawi
    N Engl J Med 358:888-99. 2008
    ..Severe anemia is a major cause of sickness and death in African children, yet the causes of anemia in this population have been inadequately studied...
  2. pmc Erythropoiesis in HIV-infected and uninfected Malawian children with severe anemia
    Job C J Calis
    Global Child Health Group, Emma Children s Hospital, Academic Medical Center, Amsterdam, The Netherlands
    AIDS 24:2883-7. 2010
    ..Despite an HIV-associated reduction in early red cell precursors, subsequent erythropoiesis appears to proceed similarly in HIV-infected and HIV-uninfected children with severe anemia...
  3. pmc Severe anaemia is not associated with HIV-1 env gene characteristics in Malawian children
    Job C J Calis
    Emma Children s Hospital, Academic Medical Centre, Amsterdam, The Netherlands
    BMC Infect Dis 8:26. 2008
    ..We therefore explored the possibility that alterations in the V1-V2-V3 fragment of HIV-1 were associated with severe anaemia...
  4. pmc Pathophysiological mechanisms of severe anaemia in Malawian children
    Michaël Boele van Hensbroek
    Malawi Liverpool Wellcome Trust Clinical Research Programme, College of Medicine, University of Malawi, Blantyre, Malawi
    PLoS ONE 5:e12589. 2010
    ..Severe anaemia is a major cause of morbidity and mortality in African children. The aetiology is multi-factorial, but interventions have often targeted only one or a few causal factors, with limited success...
  5. ncbi request reprint Second-line HIV Treatment in Ugandan Children: Favorable Outcomes and No Protease Inhibitor Resistance
    Ragna S Boerma
    Amsterdam Institute for Global Health and Development, Department of Global Health, Academic Medical Center of the University of Amsterdam, The Netherlands Global Child Health Group, Emma Children s Hospital, Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands
    J Trop Pediatr . 2016
    ..Data on pediatric second-line antiretroviral treatment (ART) outcomes are scarce, but essential to evaluate second-line and design third-line regimens...
  6. doi request reprint Conventional and novel peripheral blood iron markers compared against bone marrow in Malawian children
    Femkje A M Jonker
    Global Child Health Group, Emma Children s Hospital, Academic Medical Centre, Amsterdam, The Netherlands
    J Clin Pathol 67:717-23. 2014
    ....
  7. pmc Iron status predicts malaria risk in Malawian preschool children
    Femkje A M Jonker
    Global Child Health Group, Emma Children s Hospital, Academic Medical Centre, Amsterdam, The Netherlands
    PLoS ONE 7:e42670. 2012
    ..The aim of this study was to assess the predictive value of baseline iron status for malaria risk explicitly taking potential biases into account...
  8. pmc Low hepcidin levels in severely anemic malawian children with high incidence of infectious diseases and bone marrow iron deficiency
    Femkje A M Jonker
    Global Child Health Group, Emma Children s Hospital, Academic Medical Centre, Amsterdam, The Netherlands
    PLoS ONE 8:e78964. 2013
    ..In this study hepcidin concentrations were assessed in severely anemic children living in a highly malarious area of Malawi and evaluated against bone marrow iron in order to determine the usefulness of hepcidin as a point of care test...
  9. pmc Long term outcome of severe anaemia in Malawian children
    Kamija S Phiri
    Malawi Liverpool Wellcome Trust Clinical Research Programme, College of Medicine, Blantyre, Malawi
    PLoS ONE 3:e2903. 2008
    ..We assessed the short and long term outcome of severe anaemia in Malawian children and identified potential risk factors for death and further severe anaemia...
  10. pmc Real-time PCR demonstrates Ancylostoma duodenale is a key factor in the etiology of severe anemia and iron deficiency in Malawian pre-school children
    Femkje A M Jonker
    Global Child Health Group, Emma Children s Hospital, Academic Medical Centre, Amsterdam, The Netherlands
    PLoS Negl Trop Dis 6:e1555. 2012
    ..Using multiplex real-time PCR, we evaluated hookworm species-specific prevalence, infection load and their contribution towards severe anemia and iron deficiency in pre-school children in Malawi...
  11. doi request reprint Accumulation of HIV-1 drug resistance after continued virological failure on first-line ART in adults and children in sub-Saharan Africa
    T Sonia Boender
    Amsterdam Institute for Global Health and Development, Department of Global Health, Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands Global Child Health Group, Emma Children s Hospital Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands
    J Antimicrob Chemother 71:2918-27. 2016
    ..The objective of this study was to evaluate the accumulation of resistance to reverse transcriptase inhibitors after continued virological failure on first-line ART, among adults and children in sub-Saharan Africa...
  12. doi request reprint Iron deficiency in children with HIV-associated anaemia: a systematic review and meta-analysis
    Michael O Esan
    Health in the Population Theme, Wellcome Trust Research Laboratories, Blantyre, Malawi
    Trans R Soc Trop Med Hyg 106:579-87. 2012
    ..Nevertheless iron deficiency is a common co-morbidity in HIV. Studies are needed to determine the role of iron deficiency in HIV-associated anaemia and the effects of iron supplementation in this population...
  13. ncbi request reprint Suboptimal Viral Suppression Rates Among HIV-Infected Children in Low- and Middle-Income Countries: A Meta-analysis
    Ragna S Boerma
    Global Child Health Group, Emma Children s Hospital
    Clin Infect Dis 63:1645-1654. 2016
    ..Global estimates of viral suppression among children in low- and middle-income countries (LMICs) are lacking...
  14. doi request reprint Short communication: high rates of thymidine analogue mutations and dual-class resistance among HIV-infected Ugandan children failing first-line antiretroviral therapy
    Kim C E Sigaloff
    PharmAccess Foundation, Amsterdam, The Netherlands
    AIDS Res Hum Retroviruses 29:925-30. 2013
    ..Methods to prevent treatment failure, including adequate pediatric formulations and alternative second-line treatment options, are urgently needed...
  15. doi request reprint HIV-associated anemia in children: a systematic review from a global perspective
    Job C J Calis
    AIDS 22:1099-112. 2008
    ..To assess the importance of anemia in HIV-infected children in western and tropical settings...