Helena Brentani

Summary

Publications

  1. pmc HOXB7 mRNA is overexpressed in pancreatic ductal adenocarcinomas and its knockdown induces cell cycle arrest and apoptosis
    Thais Chile
    Laboratory for Cellular and Molecular Endocrinology LIM 25, University of Sao Paulo Medical School, Av, Dr, Arnaldo, 455 4305, Sao Paulo, SP, 01246 903, Brazil
    BMC Cancer 13:451. 2013
  2. pmc Transcriptional alterations related to neuropathology and clinical manifestation of Alzheimer's disease
    Aderbal R T Silva
    Research Center CIPE, A C Camargo Hospital, Sao Paulo, Brazil
    PLoS ONE 7:e48751. 2012
  3. pmc Transcriptome signature of the adult mouse choroid plexus
    Fernanda Marques
    Life and Health Sciences Research Institute ICVS, School of Health Sciences, University of Minho, Campus Gualtar, 4710 057 Braga, Portugal
    Fluids Barriers CNS 8:10. 2011
  4. pmc No-match ORESTES explored as tumor markers
    Barbara P Mello
    Hospital A C Camargo, Rua Prof Antonio Prudente 211, Sao Paulo, SP, Brazil
    Nucleic Acids Res 37:2607-17. 2009
  5. ncbi request reprint Reciprocal changes in gene expression profiles of cocultured breast epithelial cells and primary fibroblasts
    Patricia Bortman Rozenchan
    Disciplina de Oncologia, Departamento de Radiologia, Faculdade de Medicina da Universidade de Sao Paulo, Hospital A C Camargo, Av Dr Arnaldo, 455, Sala 4112, Sao Paulo, SP CEP 01246 903, Brazil
    Int J Cancer 125:2767-77. 2009
  6. ncbi request reprint Differences in transcriptional effects of 1α,25 dihydroxyvitamin D3 on fibroblasts associated to breast carcinomas and from paired normal breast tissues
    Laura Tojeiro Campos
    Departamento de Radiologia e Oncologia, Faculdade de Medicina da Universidade de Sao Paulo, Av Dr Arnaldo, 455, Sala 4112, CEP 01246 903, Sao Paulo, SP, Brazil
    J Steroid Biochem Mol Biol 133:12-24. 2013
  7. pmc Repair of oxidative DNA damage, cell-cycle regulation and neuronal death may influence the clinical manifestation of Alzheimer's disease
    Aderbal R T Silva
    Laboratory of Clinical Pathology Laboratory of Medical Investigations 23 LIM 23, Department and Institute of Psychiatry, University of Sao Paulo, Medical School, Sao Paulo, Brazil
    PLoS ONE 9:e99897. 2014
  8. pmc A feature selection approach for identification of signature genes from SAGE data
    Junior Barrera
    Instituto de Matemática e Estatística, Universidade de Sao Paulo, Sao Paulo, Brazil
    BMC Bioinformatics 8:169. 2007
  9. pmc Comprehensive analysis of BRCA1, BRCA2 and TP53 germline mutation and tumor characterization: a portrait of early-onset breast cancer in Brazil
    Dirce Maria Carraro
    Laboratory of Genomics and Molecular Biology, A C Camargo Hospital, Sao Paulo, Brazil
    PLoS ONE 8:e57581. 2013
  10. ncbi request reprint Identification of protein expression signatures in gastric carcinomas using clustering analysis
    Maria D Begnami
    Department of Pathology, A C Camargo Hospital, Sao Paulo, Brazil
    J Gastroenterol Hepatol 27:378-84. 2012

Collaborators

  • Dirce Maria Carraro
  • Waleska K Martins
  • Sergio Verjovski-Almeida
  • Ana Cv Krepischi
  • Elisa N Ferreira
  • Breno S Diniz
  • Gustavo H Esteves
  • Sandro J de Souza
  • Junior Barrera
  • Beatriz de Camargo
  • Wadih Arap
  • Cíntia Milani
  • Aderbal R T Silva
  • Luiz F L Reis
  • Fernando A Soares
  • Antônio Hugo José Fróes Marques Campos
  • Elen Pereira Bastos
  • Ricardo R Brentani
  • Maria Mitzi Brentani
  • Cesar Torres
  • Rogério da Silva Fonseca
  • Carlos Alberto de Bragança Pereira
  • Renato David Puga
  • Renata E L Ferretti
  • Rafael M Rocha
  • Vladmir Cláudio Cordeiro de Lima
  • Lea T Grinberg
  • Thais Chile
  • Jose M Farfel
  • Laura Tojeiro Campos
  • Alex F Carvalho
  • Maria D Begnami
  • Ariane Machado-Lima
  • Rosimeire Aparecida Roela
  • Maria Aparecida Azevedo Koike Folgueira
  • Silvia Y Bando
  • Maria Lucia Hirata Katayama
  • Fernanda Marques
  • Fernando Augusto Soares
  • Patricia Bortman Rozenchan
  • Barbara P Mello
  • Cesar H Torres
  • Andre Montagnini
  • Mariana Maschietto
  • Luciana I Gomes
  • Beatriz S Stolf
  • Roberto Hirata
  • E Jordao Neves
  • Maria Dirlei Begnami
  • Aderbal Ruy T Silva
  • Fatima Solange Pasini
  • Wilson Jacob-Filho
  • Amanda Rusiska Piovezani
  • Isabela Werneck Cunha
  • César Henrique Torres
  • Eloisa Helena Ribeiro Olivieri
  • Ana Cecília Feio Santos
  • Leandro Lima
  • Durvanei Augusto Maria
  • Márcia Saldanha Kubrusly
  • Vivian Lika Hashimoto
  • Telesforo Bacchella
  • Graziela Machado Gruner Turco Spilborghs
  • Adriana Abalen Martins Dias
  • Sarah Martins Marques
  • Vanessa de Jesus R de Paula
  • Gilles Landman
  • Mariana Morato-Marques
  • Maria Lúcia Cardillo Corrêa-Giannella
  • Ricardo Rodrigues Giorgi
  • Maria Angela Henriques Zanella Fortes
  • Karina Braga Ribeiro
  • Cíntia Flores Rolim
  • Estela Maria Novak
  • Alex Fiorini de Carvalho
  • Andre Abreu Silva
  • Wilson Jacob Filho
  • Eloísa Ribeiro Olivieri
  • Wilson Luiz Costa
  • José Humberto T G Fregnani
  • Diogo Patrão
  • Suely Nonogaki
  • Vera Cristina Prescinoti
  • Luiz Paulo Camargo
  • Louise Danielle De Carvalho Mota
  • Ricardo Renzo Brentani
  • Paulo J S Silva
  • Leandro A Lima
  • Leandro de A Lima
  • Daniel H Geschwind

Detail Information

Publications22

  1. pmc HOXB7 mRNA is overexpressed in pancreatic ductal adenocarcinomas and its knockdown induces cell cycle arrest and apoptosis
    Thais Chile
    Laboratory for Cellular and Molecular Endocrinology LIM 25, University of Sao Paulo Medical School, Av, Dr, Arnaldo, 455 4305, Sao Paulo, SP, 01246 903, Brazil
    BMC Cancer 13:451. 2013
    ..In the present study, the effects arising from the knockdown of HOXB7 in PDAC cell lines was investigated...
  2. pmc Transcriptional alterations related to neuropathology and clinical manifestation of Alzheimer's disease
    Aderbal R T Silva
    Research Center CIPE, A C Camargo Hospital, Sao Paulo, Brazil
    PLoS ONE 7:e48751. 2012
    ....
  3. pmc Transcriptome signature of the adult mouse choroid plexus
    Fernanda Marques
    Life and Health Sciences Research Institute ICVS, School of Health Sciences, University of Minho, Campus Gualtar, 4710 057 Braga, Portugal
    Fluids Barriers CNS 8:10. 2011
    ..abstract:..
  4. pmc No-match ORESTES explored as tumor markers
    Barbara P Mello
    Hospital A C Camargo, Rua Prof Antonio Prudente 211, Sao Paulo, SP, Brazil
    Nucleic Acids Res 37:2607-17. 2009
    ..Lists of 1007 differentially expressed sequences, and the 291 potentially noncoding tumor markers were provided...
  5. ncbi request reprint Reciprocal changes in gene expression profiles of cocultured breast epithelial cells and primary fibroblasts
    Patricia Bortman Rozenchan
    Disciplina de Oncologia, Departamento de Radiologia, Faculdade de Medicina da Universidade de Sao Paulo, Hospital A C Camargo, Av Dr Arnaldo, 455, Sala 4112, Sao Paulo, SP CEP 01246 903, Brazil
    Int J Cancer 125:2767-77. 2009
    ..Our data indicate that interactions between breast fibroblasts and basal epithelial cells resulted in alterations in the genomic profiles of both cell types which may help to clarify some aspects of this heterotypic signaling...
  6. ncbi request reprint Differences in transcriptional effects of 1α,25 dihydroxyvitamin D3 on fibroblasts associated to breast carcinomas and from paired normal breast tissues
    Laura Tojeiro Campos
    Departamento de Radiologia e Oncologia, Faculdade de Medicina da Universidade de Sao Paulo, Av Dr Arnaldo, 455, Sala 4112, CEP 01246 903, Sao Paulo, SP, Brazil
    J Steroid Biochem Mol Biol 133:12-24. 2013
    ..Co-expression network and interactome analysis of genes commonly regulated by 1,25D in NAFs and CAFs revealed differences in their co-expression values, suggesting that 1,25D effects in NAFs are distinct from those triggered in CAFs...
  7. pmc Repair of oxidative DNA damage, cell-cycle regulation and neuronal death may influence the clinical manifestation of Alzheimer's disease
    Aderbal R T Silva
    Laboratory of Clinical Pathology Laboratory of Medical Investigations 23 LIM 23, Department and Institute of Psychiatry, University of Sao Paulo, Medical School, Sao Paulo, Brazil
    PLoS ONE 9:e99897. 2014
    ..This study indicates that, even in the setting of pathological AD, healthy cognition may be associated with a preserved repair to DNA damage, cell-cycle regulation, and cell death in post-mitotic neurons...
  8. pmc A feature selection approach for identification of signature genes from SAGE data
    Junior Barrera
    Instituto de Matemática e Estatística, Universidade de Sao Paulo, Sao Paulo, Brazil
    BMC Bioinformatics 8:169. 2007
    ..Due to important differences in the probabilistic models of microarray and SAGE technologies, it is important to develop suitable techniques to select specific genes from SAGE measurements...
  9. pmc Comprehensive analysis of BRCA1, BRCA2 and TP53 germline mutation and tumor characterization: a portrait of early-onset breast cancer in Brazil
    Dirce Maria Carraro
    Laboratory of Genomics and Molecular Biology, A C Camargo Hospital, Sao Paulo, Brazil
    PLoS ONE 8:e57581. 2013
    ..Additionally, the data revealed molecular factors that potentially trigger the tumor development in young patients...
  10. ncbi request reprint Identification of protein expression signatures in gastric carcinomas using clustering analysis
    Maria D Begnami
    Department of Pathology, A C Camargo Hospital, Sao Paulo, Brazil
    J Gastroenterol Hepatol 27:378-84. 2012
    ..In the present study, we identified biologically- and clinically-meaningful groups of GC by hierarchical clustering analysis of immunohistochemical protein expression...
  11. ncbi request reprint TNF-alpha and melphalan modulate a specific group of early expressed genes in a murine melanoma model
    Vladmir Cláudio Cordeiro de Lima
    Laboratório de Inflamação e Câncer, Fundacao Antonio Prudente, Hospital AC Camargo, Sao Paulo, Brazil
    Cytokine 62:217-25. 2013
    ....
  12. ncbi request reprint Evaluation of quantitative rt-PCR using nonamplified and amplified RNA
    Elisa N Ferreira
    Laboratory of Genomics and Molecular Biology A C Camargo Hospital, Institute of Biosciences, University of Sao Paulo USP, Sao Paulo, Brazil
    Diagn Mol Pathol 19:45-53. 2010
    ..The use of cDNA that is converted from both A and NA RNA in a single qRT-PCR experiment clearly creates bias in relative gene expression data...
  13. ncbi request reprint Expression profile of malignant and nonmalignant lesions of esophagus and stomach: differential activity of functional modules related to inflammation and lipid metabolism
    Luciana I Gomes
    Ludwig Institute for Cancer Research, Sao Paulo, Brazil
    Cancer Res 65:7127-36. 2005
    ....
  14. pmc Poly (A)+ transcriptome assessment of ERBB2-induced alterations in breast cell lines
    Dirce Maria Carraro
    Centro Internacional de Ensino e Pesquisa, Hospital AC Camargo, Sao Paulo, Sao Paulo, Brazil
    PLoS ONE 6:e21022. 2011
    ....
  15. pmc MicroRNAs discriminate familial from sporadic non-BRCA1/2 breast carcinoma arising in patients ≤35 years
    Elen Pereira Bastos
    Oncology and Radiology Department, Laboratory of Medical Investigation 24 LIM 24, University of Sao Paulo, Medical School, Sao Paulo, Brazil
    PLoS ONE 9:e101656. 2014
    ..MiR-mRNA co-expression analysis allowed us to identify changes in the miR-mRNA regulation that were able to distinguish tumors from familial and sporadic young BC patients non-carriers of BRCA mutations. ..
  16. ncbi request reprint Molecular profiling of isolated histological components of wilms tumor implicates a common role for the Wnt signaling pathway in kidney and tumor development
    Mariana Maschietto
    Laboratories of Genomics and Molecular Biology, Hospital A C Camargo, Sao Paulo, Brazil
    Oncology 75:81-91. 2008
    ..Taken together, these results provided molecular evidence of the recapitulation of the embryonic kidney by WT as well as involvement of the Wnt pathway in the earliest events of WT onset...
  17. ncbi request reprint Mining ORESTES no-match database: can we still contribute to cancer transcriptome?
    Rogério da Silva Fonseca
    Laboratório de Bioinformática, Hospital do Cancer, Sao Paulo, SP, Brazil
    Genet Mol Res 5:24-32. 2006
    ..We can conclude that after clean up of the no-match dataset, we still have about 939 new exons and 165 unpredicted genes that could complete the prostate or breast transcriptome...
  18. ncbi request reprint Expression profile of malignant and non-malignant diseases of the thyroid gland reveals altered expression of a common set of genes in goiter and papillary carcinomas
    Beatriz S Stolf
    Ludwig Institute for Cancer Research, Sao Paulo, Brazil Instituto de Química, USP, Sao Paulo, Brazil
    Cancer Lett 227:59-73. 2005
    ....
  19. pmc Hippocampal CA3 transcriptome signature correlates with initial precipitating injury in refractory mesial temporal lobe epilepsy
    Silvia Y Bando
    Department of Pediatrics, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil
    PLoS ONE 6:e26268. 2011
    ..Texture analyses on MRI images of dentate gyrus were conducted in a subset of surgically removed sclerotic hippocampi for identifying IPI-associated histo-radiological alterations...
  20. ncbi request reprint The value of a tumor bank in the development of cancer research in Brazil: 13 years of experience at the a C camargo hospital
    Antônio Hugo José Fróes Marques Campos
    1 A C Camargo Hospital Biobank, A C Camargo Hospital Antonio Prudente Foundation, Sao Paulo, SP, Brazil
    Biopreserv Biobank 10:168-73. 2012
    ..We conclude that biobanking should be part of the strategy employed by scientists and research institutions dedicated to the study of human diseases. ..
  21. ncbi request reprint Gene expression arrays in cancer research: methods and applications
    Ricardo R Brentani
    Ludwig Institute for Cancer Research, Sao Paulo, Brazil
    Crit Rev Oncol Hematol 54:95-105. 2005
    ..Hence, we shall also highlight some of the already available and promising applications of array technology on the day-to-day practice of oncology...
  22. pmc Germline DNA copy number variation in familial and early-onset breast cancer
    Ana Cv Krepischi
    National Institute of Science and Technology in Oncogenomics, AC Camargo Hospital, Rua Taguá 440, 01508 010, Sao Paulo, Brazil
    Breast Cancer Res 14:R24. 2012
    ..We evaluated the role of germline CNVs in breast cancer susceptibility, in particular those with low population frequencies (rare CNVs), which are more likely to cause disease."..