Lilian Castilho

Summary

Affiliation: Universidade Estadual de Campinas
Country: Brazil

Publications

  1. pmc Duffy blood group gene polymorphisms among malaria vivax patients in four areas of the Brazilian Amazon region
    Carlos E Cavasini
    Centro de Investigação de Microrganismos, Faculdade de Medicina de Sao Jose do Rio Preto, Av, Brigadeiro Faria Lima, 5416, Sao Jose do Rio Preto, São Paulo State 15090 000, Brazil
    Malar J 6:167. 2007
  2. ncbi The value of DNA analysis for antigens in the Duffy blood group system
    Lilian Castilho
    Hemocentro, UNICAMP, Campinas, Rua Carlos Chagas 480, Cidade Universitária Barão Geraldo, Campinas, Sao Paulo, Brazil
    Transfusion 47:28S-31S. 2007
  3. ncbi High frequency of partial DIIIa and DAR alleles found in sickle cell disease patients suggests increased risk of alloimmunization to RhD
    L Castilho
    Hemocentro Unicamp, Campinas, SP, Brazil
    Transfus Med 15:49-55. 2005
  4. ncbi A novel FY allele in Brazilians
    L Castilho
    Hemocentro, UNICAMP, Campinas, Sao Paulo, Brazil
    Vox Sang 87:190-5. 2004
  5. ncbi Weakened expression of 'e' owing to concomitant occurrence of Cys16 and Val245 (VS antigen)
    A Rodrigues
    Hemocentro da UNICAMP, SP, Brazil
    Vox Sang 86:136-40. 2004
  6. ncbi Blood group genotyping facilitates transfusion of beta-thalassemia patients
    Lilian Castilho
    Hemocentro Unicamp, Campinas, SP, Brasil
    J Clin Lab Anal 16:216-20. 2002
  7. ncbi DNA-based typing of blood groups for the management of multiply-transfused sickle cell disease patients
    Lilian Castilho
    Hematology and Hemotherapy Center, State University of Campinas UNICAMP, Campinas, SP, Brazil
    Transfusion 42:232-8. 2002
  8. doi How do we identify RHD variants using a practical molecular approach?
    Carine Prisco Arnoni
    Colsan Associação Beneficente de Coleta de Sangue, Sao Paulo, SP, Brazil
    Transfusion 54:962-9. 2014
  9. ncbi A novel DI*A allele without the Band 3-Memphis mutation in Amazonian Indians
    W Baleotti
    Hemocentro, Faculdade de Medicina, Marilia, Sao Paulo, Brazil
    Vox Sang 84:326-30. 2003
  10. ncbi Blood group genotyping in a population of highly diverse ancestry
    J Pellegrino
    Hemocentro Unicamp, Campinas, SP, Brazil
    J Clin Lab Anal 15:8-13. 2001

Collaborators

  • Jill R Storry
  • Carlos Eugênio Cavasini
  • Wilson Baleotti
  • Marion Reid
  • M Rios
  • Antonio Fabron
  • A Rodrigues
  • Jeane Eliete Laguila Visentainer
  • Asok Chaudhuri
  • J Poole
  • I N Machado
  • Martin L Olsson
  • Ricardo Luiz Dantas Machado
  • Carine Prisco Arnoni
  • Flávia Roche Moreira Latini
  • Janaína Guilhem Muniz
  • Jordão Pellegrino
  • Diana Gazito
  • Jose Augusto Barreto
  • Ane C Gaspardi
  • Emília Ângela Sippert
  • Camila Rodrigues
  • Gláucia A S Guelsin
  • Emilia Sippert
  • Rosangela De Medeiros Person
  • Simone Cristina Olenscki Gilli
  • Tatiane Aparecida de Paula Vendrame
  • Rosangela de Medeiros Person
  • Daiane Cobianchi da Costa
  • Daphne R T Amaral
  • Débora Castilho Credidio
  • J Pellegrino
  • K R Ribeiro
  • F F Costa
  • Alissa Schawalder
  • Laércio Melo
  • M Mota
  • K A Rosa
  • Emília A Sippert
  • Mayra Dorigan de Macedo
  • Fernando F Costa
  • Marcelo Addas-Carvalho
  • Sara Teresinha Ollala Saad
  • Fernando Ferreira Costa
  • Hugo Vicentin Alves
  • Sara T O Saad
  • Tatiana Aparecida de Paula Vendrame
  • Paula de Melo Campos
  • Debora Machado
  • Claudia R Fujita
  • Fabiola Traina
  • Glaucia Guelsin
  • Sara S T O Saad
  • Simone Gilli
  • Simone C O Gilli
  • Fabrício Oliveira Carvalho
  • Janaína Guinhem Muniz
  • Tatiane Aparecida de Paula
  • Rosangela Medeiros Person
  • Rosangela Duarte de Medeiros Person
  • Janete Maria Cerutti
  • Karina Antero Rosa Ribeiro
  • André Uchimura Bastos
  • Gláucia Andréia Soares Guelsin
  • Débora C Credidio
  • M H Guarnieri
  • D C da Costa
  • Kim Hue-Roye
  • J P Baldon
  • Celso Bianco
  • N L Fonseca
  • E K Carboni
  • S T Stinghen
  • A M Watanabe
  • V I Powell
  • J M Kutner
  • C Lomas-Francis
  • M M F Jucksch
  • C A De Souza

Detail Information

Publications38

  1. pmc Duffy blood group gene polymorphisms among malaria vivax patients in four areas of the Brazilian Amazon region
    Carlos E Cavasini
    Centro de Investigação de Microrganismos, Faculdade de Medicina de Sao Jose do Rio Preto, Av, Brigadeiro Faria Lima, 5416, Sao Jose do Rio Preto, São Paulo State 15090 000, Brazil
    Malar J 6:167. 2007
    ..vivax malaria patients from four different Brazilian endemic areas is reported, exploring significant associations between blood group variants and susceptibility or resistance to malaria...
  2. ncbi The value of DNA analysis for antigens in the Duffy blood group system
    Lilian Castilho
    Hemocentro, UNICAMP, Campinas, Rua Carlos Chagas 480, Cidade Universitária Barão Geraldo, Campinas, Sao Paulo, Brazil
    Transfusion 47:28S-31S. 2007
  3. ncbi High frequency of partial DIIIa and DAR alleles found in sickle cell disease patients suggests increased risk of alloimmunization to RhD
    L Castilho
    Hemocentro Unicamp, Campinas, SP, Brazil
    Transfus Med 15:49-55. 2005
    ..Three patients were anti-D immunized (DAR, n = 1; DIIIa/DAR, n = 2). These findings suggest that SCD patients who are candidates for chronic transfusion may benefit from genotyping for DIIIa and DAR to prevent alloimmunization...
  4. ncbi A novel FY allele in Brazilians
    L Castilho
    Hemocentro, UNICAMP, Campinas, Sao Paulo, Brazil
    Vox Sang 87:190-5. 2004
    ..These findings highlight the importance of establishing the incidence and nature of molecular events that impact on Duffy expression in different populations...
  5. ncbi Weakened expression of 'e' owing to concomitant occurrence of Cys16 and Val245 (VS antigen)
    A Rodrigues
    Hemocentro da UNICAMP, SP, Brazil
    Vox Sang 86:136-40. 2004
    ..This study investigated the association of Cys16 and/or VS with the RHCE ce alleles in a cohort of sickle cell disease (SCD) patients phenotyped as R(0)r or R(0)R(0) and rr...
  6. ncbi Blood group genotyping facilitates transfusion of beta-thalassemia patients
    Lilian Castilho
    Hemocentro Unicamp, Campinas, SP, Brasil
    J Clin Lab Anal 16:216-20. 2002
    ....
  7. ncbi DNA-based typing of blood groups for the management of multiply-transfused sickle cell disease patients
    Lilian Castilho
    Hematology and Hemotherapy Center, State University of Campinas UNICAMP, Campinas, SP, Brazil
    Transfusion 42:232-8. 2002
    ..The usefulness of DNA genotyping for RBC antigens as a tool for the management of multiply-transfused patients with sickle cell disease (SCD) to overcome the limitations of hemagglutination assays was evaluated...
  8. doi How do we identify RHD variants using a practical molecular approach?
    Carine Prisco Arnoni
    Colsan Associação Beneficente de Coleta de Sangue, Sao Paulo, SP, Brazil
    Transfusion 54:962-9. 2014
    ..Essentially, we demonstrate that sequencing of all RHD exons is not necessary for the identification of the majority of known D variants. ..
  9. ncbi A novel DI*A allele without the Band 3-Memphis mutation in Amazonian Indians
    W Baleotti
    Hemocentro, Faculdade de Medicina, Marilia, Sao Paulo, Brazil
    Vox Sang 84:326-30. 2003
    ..It is reported that Memphis II is associated with Dia. In a study designed to determine the frequency of the DI*A/DI*B and 166A>G polymorphisms in different populations in Brazil, we found a new DI*A allele...
  10. ncbi Blood group genotyping in a population of highly diverse ancestry
    J Pellegrino
    Hemocentro Unicamp, Campinas, SP, Brazil
    J Clin Lab Anal 15:8-13. 2001
    ..Essentially, 30.5 % of the donors with the FY B gene typed as Fy(b-) because of mutations in the GATA box. This information is very useful for the management of transfusion dependent patients...
  11. ncbi Fetal rhd genotyping from maternal plasma in a population with a highly diverse ethnic background
    Isabela Nelly Machado
    Departamento de Tocoginecologia da Universidade Estadual de Campinas e Hemocentro Unicamp, Universidade Estadual de Campinas, Campinas, SP
    Rev Assoc Med Bras (1992) 52:232-5. 2006
    ..To establish the performance of conventional PCR as a noninvasive method for fetal genotyping, by free fetal DNA analysis of distinct RHD regions from maternal plasma, in a population of a diverse ethnic origin...
  12. pmc A new strategy to identify rare blood donors: single polymerase chain reaction multiplex SNaPshot reaction for detection of 16 blood group alleles
    Flávia Roche Moreira Latini
    Colsan Blood Collection Centre, Sao Paulo, Brazil
    Blood Transfus 12:s256-63. 2014
    ....
  13. ncbi Serologic and molecular characterization of D variants in Brazilians: impact for typing and transfusion strategy
    Débora Castilho Credidio
    Instituto Nacional de Ciência e Tecnologia do Sangue, Hemocentro, UNICAMP, Rua Carlos Chagas, 480, Caixa Postal 6198, CEP 13081 970 Barão Geraldo, Campinas, SP, Brazil
    Immunohematology 27:6-11. 2011
    ..This distinction is important for optimized management of D– RBC units and for the prevention of anti-D–related hemolytic disease of the fetus and newborn...
  14. doi A PCR-based strategy for Dombrock screening in Brazilian blood donors reveals a novel allele: the DO* A-WL
    Wilson Baleotti
    Hemocentro, Faculdade de Medicina, Marilia, Sao Paulo, Brazil
    J Clin Lab Anal 25:79-82. 2011
    ..Based on this, we employed a PCR-based strategy to screen DO alleles (DO(*) A, DO(*) B, HY(*) 1, HY(*) 2 and JO) in Brazilians...
  15. doi Fetal RHD genotyping by analysis of maternal plasma in a mixed population
    Daphne R T Amaral
    Hemocentro, UNICAMP, Campinas, Sao Paulo, Brazil
    J Clin Lab Anal 25:100-4. 2011
    ..We assessed the accuracy of fetal RHD genotyping by analysis of maternal plasma in a multi-ethnic population...
  16. ncbi Presence of the RHD pseudogene and the hybrid RHD-CE-D(s) gene in Brazilians with the D-negative phenotype
    A Rodrigues
    Hemocentro, Universidade Estadual de Campinas, Campinas, SP, Brasil
    Braz J Med Biol Res 35:767-73. 2002
    ..These data confirm that the inclusion of two different multiplex PCR for RHD is essential to test the D-negative Brazilian population in order to avoid false-positive typing of polytransfused patients and fetuses...
  17. pmc Frequency of Wr(a) antigen and anti-Wr(a) in Brazilian blood donors
    Janaína Guilhem Muniz
    Associação Beneficente de Coleta de Sangue COLSAN, Sao Paulo, SP, Brazil Electronic address
    Rev Bras Hematol Hemoter 37:316-9. 2015
    ..Anti-Wr(a) is a naturally occurring antibody that is found in approximately 1-2% of blood donors. The aim of this study was to determine the frequency of Wr(a) and anti-Wr(a) in Brazilian blood donors...
  18. doi Novel RHAG allele encoding the Rh(null) phenotype in Brazil
    Carine Prisco Arnoni
    Colsan Associação Beneficente de Coleta de Sangue, Sao Paulo, SP, Brazil
    Transfusion 55:2521-2. 2015
    ..In this study, we show a novel allele in a Brazilian pregnant woman encoding the Rhnull phenotype due to a change in RHAG exon2 c.310C>T, which leads to a premature stop codon (Gln104Stop). ..
  19. pmc An easy and efficient strategy for KEL genotyping in a multiethnic population
    Carine Prisco Arnoni
    Associação Beneficente de Coleta de Sangue COLSAN, Sao Paulo, SP, Brazil
    Rev Bras Hematol Hemoter 35:99-102. 2013
    ..This study proposes three polymerase chain reaction genotyping protocols to analyze the single nucleotide polymorphisms responsible for six Kell antithetic antigens expressed in a Brazilian population...
  20. ncbi Twelve years of the Brazilian External Quality Assessment Program in Immunohematology: benefits of the program
    Laércio Melo
    Hemocentro da UNICAMP, Sao Paulo, Brazil
    J Clin Lab Anal 19:209-18. 2005
    ..We found that a well-organized external proficiency program can contribute to the improvement of quality of testing in Immunohematology...
  21. ncbi Frequencies of ABO, MNSs, and Duffy phenotypes among blood donors and malaria patients from four Brazilian Amazon areas
    Carlos Eugênio Cavasini
    Center for Microorganisms Investigation, Department of Dermatological, Infectious, and Parasitical Diseases, Faculty of Medicine of São José do Rio Preto, Av Brigadeiro Faria Lima 5416, São José do Rio Preto 15090 000, Sao Paulo, Brazil
    Hum Biol 78:215-9. 2006
    ..Some of the Duffy phenotypes showed significant correlation between donors and malaria patients in different areas. These data are an additional contribution to the establishment of differential host susceptibility to malaria...
  22. doi DNA array analysis for red blood cell antigens facilitates the transfusion support with antigen-matched blood in patients with sickle cell disease
    K R Ribeiro
    Hemocentro Unicamp, Rua Carlos Chagas 480, Campinas, Sao Paulo, Brazil
    Vox Sang 97:147-52. 2009
    ..To overcome this problem we developed an effective strategy to meet needs of supplying RBC-compatible units to SCD patients using DNA arrays...
  23. pmc Clinically relevant RHD-CE genotypes in patients with sickle cell disease and in African Brazilian donors
    Ane C Gaspardi
    Campinas Blood Centre, UNICAMP, Campinas, Sao Paulo, Brazil
    Blood Transfus 14:449-54. 2016
    ..In this study, we characterised variant RH alleles encoding partial antigens and/or lacking high prevalence antigens in patients with SCD and in African Brazilian donors, in order to support antigen-matched blood for transfusion...
  24. doi HLA-DRB1*07:01 allele is primarily associated with the Diego a alloimmunization in a Brazilian population
    Wilson Baleotti
    Faculty of Medicine of Marília FAMEMA, Marilia, Sao Paulo, Brazil
    Transfusion 54:2468-76. 2014
    ....
  25. ncbi A review of the JR blood group system
    Lilian Castilho
    PhD corresponding author, Professor and Researcher, Hemocentro, UNICAMP, Rua Carlos Chagas 480, Campinas, SP, Brazil, 13083 870
    Immunohematology 29:63-8. 2013
    ..1. The Jr(a-) phenotype mostly results from recessive inheritance of ABCG2 null alleles caused by frameshift or nonsense changes...
  26. doi DARC (Duffy) and BCAM (Lutheran) reduced expression in thyroid cancer
    Flávia Roche Moreira Latini
    Colsan Associação Beneficente de Coleta de Sangue, Avenida Jandira 1260, Indianopolis, Sao Paulo, SP, CEP 04080 006, Brazil
    Blood Cells Mol Dis 50:161-5. 2013
    ..We, also, found a correlation between decreased BCAM expression and tumor size or presence of metastasis. DARC and BCAM expression was associated with pathogenesis of thyroid carcinoma and correlated with clinical-pathological features...
  27. ncbi Dombrock gene analysis in Brazilian people reveals novel alleles
    W Baleotti
    Hemocentro, Faculdade de Medicina, Marilia, SP, Brazil
    Vox Sang 91:81-7. 2006
    ..Although the molecular background of Dombrock alleles is well defined, no studies have been conducted in the Brazilian population...
  28. doi Red blood cell alloimmunization in patients with sickle cell disease: correlation with HLA and cytokine gene polymorphisms
    Emília Ângela Sippert
    Hematology and Hemotherapy Center, State University of Campinas, UNICAMP, Campinas, Sao Paulo, Brazil
    Transfusion . 2016
    ..Our hypothesis is that genetic polymorphisms are associated with RBC alloimmunization...
  29. pmc Variant RH alleles and Rh immunisation in patients with sickle cell disease
    Emilia Sippert
    National Institute of Science and Blood Technology, Campinas Centre Blood, UNICAMP, Campinas, Brazil
    Blood Transfus 13:72-7. 2015
    ..In this study, we characterised variant RH alleles in 31 SCD patients who made antibodies to Rh antigens despite antigen-positive status and evaluated the clinical significance of the antibodies produced...
  30. ncbi Anti-D alloimmunization by weak D type 1 red blood cells with a very low antigen density
    M Mota
    Departamento de Hemoterapia, Hospital Israelita Albert Einstein, SP, Brazil
    Vox Sang 88:130-5. 2005
  31. pmc Molecular matching for Rh and K reduces red blood cell alloimmunisation in patients with myelodysplastic syndrome
    Gláucia A S Guelsin
    Hemocentro Unicamp, Campinas State University, Campinas, Sao Paulo, Brazil
    Blood Transfus 13:53-8. 2015
    ..We also examined a possible association of HLA class II alleles with red blood cell (RBC) alloimmunisation...
  32. pmc Molecular matching of red blood cells is superior to serological matching in sickle cell disease patients
    Daiane Cobianchi da Costa
    Universidade Estadual de Campinas UNICAMP, Campinas, SP, Brazil
    Rev Bras Hematol Hemoter 35:35-8. 2013
    ..To evaluate the usefulness of DNA methods to provide a means to precisely genotypically match donor blood units for the antigen-negative type of 35 sickle cell disease patients...
  33. ncbi Rhnull syndrome: identification of a novel mutation in RHce
    K A Rosa
    Hemocentro Unicamp, Campinas, SP, Brazil
    Transfusion 45:1796-8. 2005
    ..A novel mutation in RHce was identified in two Caucasian Brazilian girls with the amorph type of Rh(null) who were born to parents who were first cousins...
  34. ncbi Analysis in non-human primates reveals that the ancestral Band 3 gene encodes Dib and the Band 3-Memphis phenotype
    Alissa Schawalder
    Immunohematology and Immunochemisry Laboratories, New York Blood Center, New York, NY 10021, USA
    J Med Primatol 35:144-8. 2006
    ..We determined the orthologue nucleotide sequences corresponding to these two polymorphic sites, Di(a)/Di(b) (2561T > C; Leu854Pro) and Band 3-Memphis(166A > G; Lys56Glu) in several nonhuman primates...
  35. ncbi Identification of six new alleles at the FUT1 and FUT2 loci in ethnically diverse individuals with Bombay and Para-Bombay phenotypes
    Jill R Storry
    Blood Center, Lund University Hospital and Department of Hematology and Transfusion Medicine, Lund University, Lund, Sweden
    Transfusion 46:2149-55. 2006
    ..Samples from seven individuals of different geographic backgrounds whose red blood cells had an apparent Bombay or para-Bombay phenotype were investigated. Among these, novel FUT1 and FUT2 alleles were identified...
  36. ncbi Plasmodium vivax infection among Duffy antigen-negative individuals from the Brazilian Amazon region: an exception?
    Carlos Eugênio Cavasini
    Faculty of Medicine, Sao Jose do Rio Preto, Av Brigadeiro Faria Lima 5416, 15090 000 Sao Jose do Rio Preto, Sao Paulo State, Brazil
    Trans R Soc Trop Med Hyg 101:1042-4. 2007
    ..vivax-like. Additional efforts are necessary in order to clarify the evidence that P. vivax is being transmitted among Duffy blood group-negative patients from the Brazilian Amazon region...