Antonio L Braga

Summary

Affiliation: Universidade Federal de Santa Maria
Country: Brazil

Publications

  1. ncbi request reprint Diphenyl diselenide decreases the prevalence of vacuous chewing movements induced by fluphenazine in rats
    Roselei Fachinetto
    Departamento de Quimica, Programa de Pos Graduacao em Bioquimica Toxicologica, Universidade Federal de Santa Maria, 97105 900, Santa Maria, RS, Brazil
    Psychopharmacology (Berl) 194:423-32. 2007
  2. ncbi request reprint Aziridine sulfides and disulfides as catalysts for the enantioselective addition of diethylzinc to aldehydes
    Antonio L Braga
    Departamento de Quimica, Universidade Federal de Santa Maria, 97105 900 Santa Maria RS, Brazil
    Chem Commun (Camb) . 2004
  3. ncbi request reprint Catalytic enantioselective arylation of aldehydes: boronic acids as a suitable source of transferable aryl groups
    Antonio L Braga
    Departamento de Quimica, Universidade Federal de Santa Maria, 97105 900, Santa Maria, RS, Brazil
    Chem Commun (Camb) . 2005
  4. doi request reprint Synthesis and application of chiral beta-amino disulfides as ligands for the enantioselective addition of diethylzinc to aldehydes
    Antonio L Braga
    Departamento de Quimica, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil
    Chirality 20:839-45. 2008
  5. ncbi request reprint Efficient synthesis of chiral beta-seleno amides via ring-opening reaction of 2-oxazolines and their application in the palladium-catalyzed asymmetric allylic alkylation
    Antonio L Braga
    Departamento de Quimica, Universidade Federal de Santa Maria, RS, Brazil
    J Org Chem 70:9021-4. 2005
  6. doi request reprint Acceleration of arylzinc formation and its enantioselective addition to aldehydes by microwave irradiation and aziridine-2-methanol catalysts
    Antonio L Braga
    Universidade Federal de Santa Maria, Departamento de Quimica, 97105 900, Santa Maria RS, Brazil
    J Org Chem 73:2879-82. 2008
  7. doi request reprint Synthesis of telluroamino acid derivatives with remarkable GPx like activity
    Antonio L Braga
    Departamento de Quimica, Universidade Federal de Santa Maria, 97 105 900, Santa Maria, RS, Brazil
    Org Biomol Chem 7:43-5. 2009
  8. ncbi request reprint Synthesis of new chiral aliphatic amino diselenides and their application as catalysts for the enantioselective addition of diethylzinc to aldehydes
    Antonio L Braga
    Departamento de Quimica, Universidade Federal de Santa Maria, Santa Maria, RS, 97105 900, Brazil
    Org Lett 5:2635-8. 2003
  9. ncbi request reprint Chiral seleno-amines from indium selenolates. A straightforward synthesis of selenocysteine derivatives
    Antonio L Braga
    Departamento de Quimica, Universidade Federal de Santa Maria, Santa Maria, RS, 97105 900, Brazil
    J Org Chem 71:4305-7. 2006
  10. ncbi request reprint Effects of age on reserpine-induced orofacial dyskinesia and possible protection of diphenyl diselenide
    Marilise Burger
    Departamento de Fisiologia, CCS, Curso de Mestrado Doutorado em Ciências Biológicas Bioquímica Toxicológica, Universidade Federal de Santa Maria, 97105 900 Santa Maria, RS, Brazil
    Brain Res Bull 64:339-45. 2004

Collaborators

  • Roselei Fachinetto
  • Felix Alexandre Antunes Soares
  • Vanderlei Folmer
  • Juliano Ferreira
  • Bernhard Westermann
  • Caroline Wagner
  • Daiana S Avila
  • Hélio A Stefani
  • Ludger A Wessjohann
  • Waseem Hassan
  • Gilson Zeni
  • André A Vieira
  • Marcelo Godoi
  • Eduardo E Alberto
  • Oscar E D Rodrigues
  • Claudio C Silveira
  • Jamal Rafique
  • Juliano B Azeredo
  • Vanessa Nascimento
  • Joao B T Rocha
  • Márcio W Paixão
  • Flavio A R Barbosa
  • Sumbal Saba
  • Rômulo F S Canto
  • Claudio Santi
  • Cristina W Nogueira
  • Cristiane Y Kawasoko
  • Ricardo S Schwab
  • Letiére C Soares
  • Senthil Narayanaperumal
  • Ige J Kade
  • Diego Alves
  • Daiana Silva de Avila
  • Marilise Burger
  • Alisson R Rosário
  • Eufrânio N da Silva Júnior
  • Igor R Brandão
  • Bruno C Cavalcanti
  • Eufrânio N da Silva
  • Teiliane R Carneiro
  • Claudia Pessoa
  • Wagner O Valença
  • Carlos A de Simone
  • Guilherme M Martins
  • Karen L Schott
  • Natasha L Ferreira
  • Emily P Waczuk
  • Luca Sancineto
  • Patricia Foletto
  • Luciano Dornelles
  • Paulo S Taube
  • Sydney Hartz Alves
  • Luana L Rossato
  • Kashif Gul
  • Nilda B V Barbosa
  • Cristina Wayne Nogueira
  • Diogo S Lüdtke
  • Rodrigo B Panatieri
  • Marisa C Beque
  • Joao Batista Teixeira Rocha
  • Teodoro S Kaufman
  • Luciana A Felix
  • Marcelo P Stracke
  • Jesus M Pena
  • Paulo H Menezes
  • Luciano Calegari
  • Adriano S Vieira

Detail Information

Publications30

  1. ncbi request reprint Diphenyl diselenide decreases the prevalence of vacuous chewing movements induced by fluphenazine in rats
    Roselei Fachinetto
    Departamento de Quimica, Programa de Pos Graduacao em Bioquimica Toxicologica, Universidade Federal de Santa Maria, 97105 900, Santa Maria, RS, Brazil
    Psychopharmacology (Berl) 194:423-32. 2007
    ..Chronic treatment with neuroleptics causes, as a side effect, tardive dyskinesia in humans; however, the mechanisms involved in its pathophysiology remain unclear...
  2. ncbi request reprint Aziridine sulfides and disulfides as catalysts for the enantioselective addition of diethylzinc to aldehydes
    Antonio L Braga
    Departamento de Quimica, Universidade Federal de Santa Maria, 97105 900 Santa Maria RS, Brazil
    Chem Commun (Camb) . 2004
    ....
  3. ncbi request reprint Catalytic enantioselective arylation of aldehydes: boronic acids as a suitable source of transferable aryl groups
    Antonio L Braga
    Departamento de Quimica, Universidade Federal de Santa Maria, 97105 900, Santa Maria, RS, Brazil
    Chem Commun (Camb) . 2005
    ....
  4. doi request reprint Synthesis and application of chiral beta-amino disulfides as ligands for the enantioselective addition of diethylzinc to aldehydes
    Antonio L Braga
    Departamento de Quimica, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil
    Chirality 20:839-45. 2008
    ..Enantiomeric excesses of up to 99% have been obtained using 0.5 mol % of the chiral catalysts...
  5. ncbi request reprint Efficient synthesis of chiral beta-seleno amides via ring-opening reaction of 2-oxazolines and their application in the palladium-catalyzed asymmetric allylic alkylation
    Antonio L Braga
    Departamento de Quimica, Universidade Federal de Santa Maria, RS, Brazil
    J Org Chem 70:9021-4. 2005
    ..Additionally, these new compounds were evaluated in the palladium-catalyzed asymmetric allylic alkylation, giving the alkylated products in up to 98% ee...
  6. doi request reprint Acceleration of arylzinc formation and its enantioselective addition to aldehydes by microwave irradiation and aziridine-2-methanol catalysts
    Antonio L Braga
    Universidade Federal de Santa Maria, Departamento de Quimica, 97105 900, Santa Maria RS, Brazil
    J Org Chem 73:2879-82. 2008
    ..Of the amino acid derived catalysts tested, the conformationally restricted bulky substituted aziridine-2-methanols derived from serine show the best overall performance in the formation of diarylmethanols...
  7. doi request reprint Synthesis of telluroamino acid derivatives with remarkable GPx like activity
    Antonio L Braga
    Departamento de Quimica, Universidade Federal de Santa Maria, 97 105 900, Santa Maria, RS, Brazil
    Org Biomol Chem 7:43-5. 2009
    ..A series of modular telluroamino acid derivatives with remarkable GPx-like behavior was prepared in an efficient and short two-step synthesis...
  8. ncbi request reprint Synthesis of new chiral aliphatic amino diselenides and their application as catalysts for the enantioselective addition of diethylzinc to aldehydes
    Antonio L Braga
    Departamento de Quimica, Universidade Federal de Santa Maria, Santa Maria, RS, 97105 900, Brazil
    Org Lett 5:2635-8. 2003
    ..The influence of the alkyl group substituents on the stereoselectivity has been studied, and in the best case, an enantiomeric excess up to 99% could be obtained by using only 0.5 mol % of the chiral diselenide 3a...
  9. ncbi request reprint Chiral seleno-amines from indium selenolates. A straightforward synthesis of selenocysteine derivatives
    Antonio L Braga
    Departamento de Quimica, Universidade Federal de Santa Maria, Santa Maria, RS, 97105 900, Brazil
    J Org Chem 71:4305-7. 2006
    ..As an application, the synthesis of selenocysteine and selenotreonine derivatives has been accomplished...
  10. ncbi request reprint Effects of age on reserpine-induced orofacial dyskinesia and possible protection of diphenyl diselenide
    Marilise Burger
    Departamento de Fisiologia, CCS, Curso de Mestrado Doutorado em Ciências Biológicas Bioquímica Toxicológica, Universidade Federal de Santa Maria, 97105 900 Santa Maria, RS, Brazil
    Brain Res Bull 64:339-45. 2004
    ..However, additional studies are still necessary to establish whether this compound can be considered an effective antioxidant in other models of neurotoxicity...
  11. ncbi request reprint Diethyl 2-phenyl-2 tellurophenyl vinylphosphonate: an organotellurium compound with low toxicity
    Daiana Silva de Avila
    Departamento de Quimica, Centro de Ciencias Naturais e Exatas, Universidade Federal de Santa Maria, CEP 97105 900 Santa Maria, RS, Brazil
    Toxicology 224:100-7. 2006
    ..Since diethyl 2-phenyl-2 tellurophenyl vinylphosphonate had low toxicity to mice after sub-chronic exposure, it becomes important to investigate its possible pharmacological properties...
  12. doi request reprint Ephedrine-based diselenide: a promiscuous catalyst suitable to mimic the enzyme glutathione peroxidase (GPx) and to promote enantioselective C-C coupling reactions
    Letiére C Soares
    NanoBio, Dpto de Química, CCNE, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil
    Org Biomol Chem 10:6595-9. 2012
    ..33 min (eleven times faster than PhSeSePh)...
  13. doi request reprint Modulation of diorganoyl dichalcogenides reactivity by non-bonded nitrogen interactions
    Waseem Hassan
    Departamento de Quimica, Centro de Ciencias Naturais e Exatas, Universidade Federal de Santa Maria, Santa Maria CEP 97105 900, RS, Brazil
    Chem Biol Interact 199:96-105. 2012
    ....
  14. ncbi request reprint Comparative studies on dicholesteroyl diselenide and diphenyl diselenide as antioxidant agents and their effect on the activities of Na+/K+ ATPase and delta-aminolevulinic acid dehydratase in the rat brain
    Ige J Kade
    Departamento de Quimica, Centro Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil
    Neurochem Res 33:167-78. 2008
    ....
  15. doi request reprint Straightforward synthesis of non-natural L-chalcogen and L-diselenide N-Boc-protected-γ-amino acid derivatives
    Cristiane Y Kawasoko
    Departamento de Quimica, Universidade Federal de Santa Maria, 97105 900, Santa Maria, RS, Brazil
    Org Biomol Chem 11:5173-83. 2013
    ..Also, an L-diselenide-N-Boc-γ-amino acid was prepared in good yield. This new synthetic route represents an efficient method for preparing new L-chalcogen- and L-diselenide-γ-amino acids with biological potential...
  16. ncbi request reprint Stereoselective preparation of conjugated E-enynes from E-vinylic tellurides and terminal alkynes via Sonogashira cross-coupling
    Gilson Zeni
    Departamento de Quimica, Laboratório de Bioquímica Toxicológica, UFSM, Santa Maria, RS, Brazil 97105 900
    Org Biomol Chem 2:803-5. 2004
    ..The methodology represents a general and efficient protocol for carrying out the synthesis of E-enynes under mild conditions with complete retention of configuration...
  17. doi request reprint Synthesis of diorganyl selenides mediated by zinc in ionic liquid
    Senthil Narayanaperumal
    Departamento de Quimica, Universidade Federal de Santa Maria, 97105 900, Santa Maria, Brazil
    J Org Chem 75:3886-9. 2010
    ..Compared to the usual organic solvents, BMIM-BF(4) exhibited higher performance with the advantage to be reused up to five successive runs...
  18. ncbi request reprint Vinylic tellurides: from preparation to their applicability in organic synthesis
    Gilson Zeni
    Departamento de Quimica, Universidade Federal de Santa Maria, 97105 900 Santa Maria, RS, Brazil
    Chem Rev 106:1032-76. 2006
  19. doi request reprint Catalytic chalcogenylation under greener conditions: a solvent-free sulfur- and seleno-functionalization of olefins via I2/DMSO oxidant system
    André A Vieira
    Departamento de Quimica, Universidade Federal de Santa Catarina, Florianopolis, SC, Brazil
    J Org Chem 80:2120-7. 2015
    ..This eco-friendly approach afforded the desired products in good to excellent yields in only 10 min. In addition, using the same protocol, we carried out the cyclization reaction of relevant molecules, such as lapachol derivatives. ..
  20. doi request reprint Imidazolium ionic liquids containing selenium: synthesis and antimicrobial activity
    Eduardo E Alberto
    Departamento de Quimica, Universidade Federal de Santa Maria, Santa Maria, Brazil
    Org Biomol Chem 9:1001-3. 2011
    ..Minimum inhibitory concentration revealed that these compounds are especially active against algae, and their activity is modulated by substituents attached to the selenium moiety as well as by the counterion...
  21. doi request reprint Regioselective, Solvent- and Metal-Free Chalcogenation of Imidazo[1,2-a]pyridines by Employing I2 /DMSO as the Catalytic Oxidation System
    Jamal Rafique
    Departamento de Quimica, Universidade Federal de Santa Catarina, Florianopolis, 88040 900, Brazil
    Chemistry 22:11854-62. 2016
    ..This mild, green approach allowed the preparation of different types of chalcogenated imidazo[1,2-a]pyridines with structural diversity. Furthermore, the current protocol was also extended to other N-heterocyclic cores. ..
  22. ncbi request reprint Stereoselective synthesis of enynes by nickel-catalyzed cross-coupling of divinylic chalcogenides with alkynes
    Claudio C Silveira
    Departamento de Quimica, Universidade Federal de Santa Maria, C P 5001, CEP 97105 900, RS, Brazil
    J Org Chem 68:662-5. 2003
    ....
  23. ncbi request reprint Hydroselenation of alkynes by lithium butylselenolate: an approach in the synthesis of vinylic selenides
    Gilson Zeni
    Laboratorio de Sintese, Reatividade, Avaliação, Toxicologica e Farmacologica de Organocalcogenios CCNE UFSM, 97105 900 Santa Maria RS, Brazil
    Org Lett 6:1135-8. 2004
    ..The regio- and stereochemistry of the hydroselenation depend on the nature of the substituents bonded to the alkyne...
  24. ncbi request reprint Palladium-catalyzed coupling of sp(2)-hybridized tellurides
    Gilson Zeni
    Departamento de Quimica, UFSM, 97105 900 Santa Maria, RS, Brazil
    Acc Chem Res 36:731-8. 2003
    ..In this way, vinylic tellurides can behave as aryl or vinyl carbocation equivalents. This review focuses on methods that involve the use of vinylic tellurides in palladium-catalyzed cross coupling reaction...
  25. doi request reprint Synthesis and biological evaluation of new nitrogen-containing diselenides
    Vanessa Nascimento
    Laboratorio de Sintese de Substancias de Selenio Bioativas, Centro de Ciências Físicas e Matemáticas, Departamento de Quimica, Universidade Federal de Santa Catarina, 88040 900 Florianopolis, SC, Brazil
    Eur J Med Chem 87:131-9. 2014
    ..All of the new compounds inhibited Fe(II)-induced TBARS. ..
  26. doi request reprint A solvent- and metal-free synthesis of 3-chacogenyl-indoles employing DMSO/I2 as an eco-friendly catalytic oxidation system
    Juliano B Azeredo
    Departamento de Quimica, Universidade Federal de Santa Catarina, 88040 900 Florianopolis, Santa Catarina, Brazil
    J Org Chem 79:4125-30. 2014
    ..This mild and eco-friendly approach allowed the preparation of a wide range of 3-selenyl- and 3-sulfenyl-indoles in good to excellent yields. ..
  27. ncbi request reprint 1-substituted beta-carbolines by a Pictet-Spengler cyclization with thioortho esters and carbon-carbon bond formation via N-sulfonyl iminium ions generated from N,S-sulfonyl acetals
    Claudio C Silveira
    Departamento de Quimica, Universidade Federal de Santa Maria, 97105 900, Santa Maria, RS, Brazil
    Org Lett 7:3701-4. 2005
    ..The 1-heterosubstituted beta-carbolines furnished 1-substituted beta-carbolines upon reaction with Grignard reagents and silyl derivatives under Lewis acid promotion. [reaction: see text]..
  28. doi request reprint Synthesis and evaluation of dihydropyrimidinone-derived selenoesters as multi-targeted directed compounds against Alzheimer's disease
    Flavio A R Barbosa
    Laboratório de Síntese de Substâncias Bioativas de Selênio, Centro de Ciências Físicas e Matemáticas, Departamento de Quimica, Universidade Federal de Santa Catarina, 88040 900 Florianopolis, SC, Brazil
    Bioorg Med Chem 24:5762-5770. 2016
    ....
  29. doi request reprint Hybrid compounds with two redox centres: modular synthesis of chalcogen-containing lapachones and studies on their antitumor activity
    André A Vieira
    Departamento de Quimica, UFSC, 88040 900, Florianopolis, SC, Brazil Instituto de Química, Departamento de Quimica Organica, UFBA, 40170 290, Salvador, BA, Brazil
    Eur J Med Chem 101:254-65. 2015
    ..The methodology employed allowed the preparation of the compounds from lapachol within a few minutes in a green approach. ..
  30. ncbi request reprint Chiral organoselenium-transition-metal catalysts in asymmetric transformations
    Marcelo Godoi
    Departamento de Quimica, Universidade Federal de Santa Catarina, Florianopolis, SC 88040 970, Brazil
    Dalton Trans 40:11347-55. 2011
    ..Important selective contributions within the field of chiral selenium complexes are examined, according to their applications. As final remarks, future developments and perspectives of the field are discussed...