G Lenz

Summary

Affiliation: Porto Alegre
Country: Brazil

Publications

  1. ncbi request reprint Endogenous anticancer mechanisms (EACMs)
    Guido Lenz
    Department of Biophysics and Center of Biotechnology, Federal University of Rio Grande do Sul UFRGS, Porto Alegre, RS, Brazil
    Front Biosci (Schol Ed) 4:1017-30. 2012
  2. pmc Autophagy interplay with apoptosis and cell cycle regulation in the growth inhibiting effect of resveratrol in glioma cells
    Eduardo C Filippi-Chiela
    Department of Biophysics, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
    PLoS ONE 6:e20849. 2011
  3. pmc Nuclear morphometric analysis (NMA): screening of senescence, apoptosis and nuclear irregularities
    Eduardo C Filippi-Chiela
    Department of Biophysics, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil
    PLoS ONE 7:e42522. 2012
  4. pmc Resveratrol abrogates the temozolomide-induced G2 arrest leading to mitotic catastrophe and reinforces the temozolomide-induced senescence in glioma cells
    Eduardo C Filippi-Chiela
    Department of Biophysics, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
    BMC Cancer 13:147. 2013
  5. pmc In vivo glioblastoma growth is reduced by apyrase activity in a rat glioma model
    Fernanda B Morrone
    Departamento de Bioquimica, ICBS, UFRGS, Porto Alegre, RS, Brazil
    BMC Cancer 6:226. 2006
  6. ncbi request reprint The RNA interference revolution
    G Lenz
    Departamento de Biofisica, Federal do Rio Grande do Sul, Av Benito Goncalves 9500, 91501 370 Porto Alegre, RS, Brasil
    Braz J Med Biol Res 38:1749-57. 2005
  7. doi request reprint Transient oncogenes
    G Lenz
    Department of Biophysics and Center of Biotechnology, Federal University of Rio Grande do Sul UFRGS, Porto Alegre, Brazil
    Med Hypotheses 75:660-2. 2010

Collaborators

  • Eduardo C Filippi-Chiela
  • Fernanda B Morrone
  • Maria Isabel A Edelweiss
  • Joseli Stella
  • Marcia R Wink
  • Luise Meurer
  • PatrĂ­cia Gamermann
  • Suzana Wofchuk
  • Ana Maria O Battastini
  • Diogo L Oliveira

Detail Information

Publications7

  1. ncbi request reprint Endogenous anticancer mechanisms (EACMs)
    Guido Lenz
    Department of Biophysics and Center of Biotechnology, Federal University of Rio Grande do Sul UFRGS, Porto Alegre, RS, Brazil
    Front Biosci (Schol Ed) 4:1017-30. 2012
    ..Here I will present the basic features and the importance of each EACM and review the involvement of these processes in preventing cancer growth together with their importance in cancer prevention and therapeutics...
  2. pmc Autophagy interplay with apoptosis and cell cycle regulation in the growth inhibiting effect of resveratrol in glioma cells
    Eduardo C Filippi-Chiela
    Department of Biophysics, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
    PLoS ONE 6:e20849. 2011
    ....
  3. pmc Nuclear morphometric analysis (NMA): screening of senescence, apoptosis and nuclear irregularities
    Eduardo C Filippi-Chiela
    Department of Biophysics, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil
    PLoS ONE 7:e42522. 2012
    ..This method provides a direct and objective way of screening normal, senescent, apoptotic and nuclear irregularities which may occur during failed mitosis or mitotic catastrophe, which may be very useful in basic and clinical research...
  4. pmc Resveratrol abrogates the temozolomide-induced G2 arrest leading to mitotic catastrophe and reinforces the temozolomide-induced senescence in glioma cells
    Eduardo C Filippi-Chiela
    Department of Biophysics, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
    BMC Cancer 13:147. 2013
    ..However, the mechanism of Rsv and TMZ additive toxicity, which is the aim of the present work, is not clear, especially concerning cell cycle dynamics and long term effects...
  5. pmc In vivo glioblastoma growth is reduced by apyrase activity in a rat glioma model
    Fernanda B Morrone
    Departamento de Bioquimica, ICBS, UFRGS, Porto Alegre, RS, Brazil
    BMC Cancer 6:226. 2006
    ..The objective of the present study was to test the involvement of extracellular ATP in glioblastoma growth in a rat glioma model...
  6. ncbi request reprint The RNA interference revolution
    G Lenz
    Departamento de Biofisica, Federal do Rio Grande do Sul, Av Benito Goncalves 9500, 91501 370 Porto Alegre, RS, Brasil
    Braz J Med Biol Res 38:1749-57. 2005
    ....
  7. doi request reprint Transient oncogenes
    G Lenz
    Department of Biophysics and Center of Biotechnology, Federal University of Rio Grande do Sul UFRGS, Porto Alegre, Brazil
    Med Hypotheses 75:660-2. 2010
    ..Several published evidences are used to support the proposed hypothesis. Analysis and even targeting of this new class of oncogenes could have a great impact on cancer biology, treatment and, most importantly, prevention...