Clement Hamani

Summary

Country: Brazil

Publications

  1. ncbi request reprint Inhibitory role of the zona incerta in the pilocarpine model of epilepsy
    Clement Hamani
    Depto de Fisiologia, EPM UNIFESP, SP 04023 900, Sao Paulo, Brazil
    Epilepsy Res 49:73-80. 2002
  2. ncbi request reprint Intraventricular pressure monitoring in patients with thalamic and ganglionic hemorrhages
    Clement Hamani
    Division of Neurosurgery, Hospital das Clinicas, University of Sao Paulo, Sao Paulo, SP, Brazil
    Arq Neuropsiquiatr 61:376-80. 2003
  3. doi request reprint Microinjection of GABAergic agents into the anterior nucleus of the thalamus modulates pilocarpine-induced seizures and status epilepticus
    Simone Bittencourt
    Department of Physiology, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Seizure 19:242-6. 2010
  4. doi request reprint Effects of A1 receptor agonist/antagonist on spontaneous seizures in pilocarpine-induced epileptic rats
    Beatriz Oliveira Amorim
    Disciplina de Neurofisiologia, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Epilepsy Behav 61:168-73. 2016
  5. pmc Deep brain stimulation induces antiapoptotic and anti-inflammatory effects in epileptic rats
    Beatriz O Amorim
    Disciplina de Neurofisiologia, Universidade Federal de Sao Paulo, Rua Botucatu, 862 5 andar, 04023 062, Sao Paulo, Brazil
    J Neuroinflammation 12:162. 2015
  6. doi request reprint Deep brain stimulation reverses anhedonic-like behavior in a chronic model of depression: role of serotonin and brain derived neurotrophic factor
    Clement Hamani
    Neuroimaging Research Section, Centre for Addiction and Mental Health, Toronto Western Hospital, 250 College Street, Toronto, Ontario, Canada
    Biol Psychiatry 71:30-5. 2012
  7. doi request reprint Bilateral anterior thalamic nucleus lesions are not protective against seizures in chronic pilocarpine epileptic rats
    Clement Hamani
    Departamentode Fisiologia, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Stereotact Funct Neurosurg 87:143-7. 2009
  8. pmc Effects of anterior thalamic nucleus deep brain stimulation in chronic epileptic rats
    Luciene Covolan
    Disciplina de Neurofisiologia, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    PLoS ONE 9:e97618. 2014
  9. ncbi request reprint Deep brain stimulation of the anterior nucleus of the thalamus: effects of electrical stimulation on pilocarpine-induced seizures and status epilepticus
    Clement Hamani
    Division of Neurosurgery, Toronto Western Hospital and University Health Network, University of Toronto, Toronto, Ontario, Canada
    Epilepsy Res 78:117-23. 2008
  10. ncbi request reprint Spontaneous recurrent seizures and neuropathology in the chronic phase of the pilocarpine and picrotoxin model epilepsy
    Clement Hamani
    Department of Physiology, UNIFESP EPM, R Botucatu 862, 04023 062 São Paulo SP, Brazil
    Neurol Res 24:199-209. 2002

Collaborators

  • Andres M Lozano
  • Karen D Davis
  • Luciene Covolan
  • Antonio M Rodrigues
  • Beatriz Oliveira Amorim
  • Elenn Ferreira
  • Antonio Carlos G de Almeida
  • Beatriz O Amorim
  • Maisa Ferreira Miranda
  • Jose N Nobrega
  • Luiz E Mello
  • Simone Bittencourt
  • Erich O Richter
  • Jonathan O Dostrovsky
  • Jason A Brodkey
  • Maria José S Fernandes
  • Antonio Carlos G deAlmeida
  • Diego P Nunes
  • David G de Morais
  • José Geraldo Brito
  • Ana Paula Madureira
  • Mayra C Aarão
  • Beatriz Amorim
  • Clarissa Cavarsan
  • Claudio Queiroz
  • Francisco P Dubiela
  • Danielle Andrade
  • William D Hutchison
  • Ronald R Tasker
  • Mary Pat McAndrews

Detail Information

Publications17

  1. ncbi request reprint Inhibitory role of the zona incerta in the pilocarpine model of epilepsy
    Clement Hamani
    Depto de Fisiologia, EPM UNIFESP, SP 04023 900, Sao Paulo, Brazil
    Epilepsy Res 49:73-80. 2002
    ..Our results contribute to the further characterisation of the regulatory role of the zona incerta in seizure-related phenomena, suggesting that its modulation might be a relevant target for anticonvulsant strategies...
  2. ncbi request reprint Intraventricular pressure monitoring in patients with thalamic and ganglionic hemorrhages
    Clement Hamani
    Division of Neurosurgery, Hospital das Clinicas, University of Sao Paulo, Sao Paulo, SP, Brazil
    Arq Neuropsiquiatr 61:376-80. 2003
    ..28, p=0.43) or when ICP levels and the volumes of the hematomas were compared (r=0.38, p=0.28). In addition, no significant correlations were observed concerning the final outcome of the patients and the variables previously evaluated...
  3. doi request reprint Microinjection of GABAergic agents into the anterior nucleus of the thalamus modulates pilocarpine-induced seizures and status epilepticus
    Simone Bittencourt
    Department of Physiology, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Seizure 19:242-6. 2010
    ..The percentage of animals that developed SE was similar across groups. Overall, microinjection of high doses of muscimol into the AN delayed the occurrence of pilocarpine-induced seizures and SE but was not able to prevent these events...
  4. doi request reprint Effects of A1 receptor agonist/antagonist on spontaneous seizures in pilocarpine-induced epileptic rats
    Beatriz Oliveira Amorim
    Disciplina de Neurofisiologia, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Epilepsy Behav 61:168-73. 2016
    ..In summary, the administration of A1 agonists reduced hippocampal excitability but not the frequency of spontaneous recurrent seizures in chronic epileptic rats, whereas A1 receptor antagonists increased both. ..
  5. pmc Deep brain stimulation induces antiapoptotic and anti-inflammatory effects in epileptic rats
    Beatriz O Amorim
    Disciplina de Neurofisiologia, Universidade Federal de Sao Paulo, Rua Botucatu, 862 5 andar, 04023 062, Sao Paulo, Brazil
    J Neuroinflammation 12:162. 2015
    ..Status epilepticus (SE) is a severe condition that may lead to hippocampal cell loss and epileptogenesis. Some of the mechanisms associated with SE-induced cell death are excitotoxicity, neuroinflammation, and apoptosis...
  6. doi request reprint Deep brain stimulation reverses anhedonic-like behavior in a chronic model of depression: role of serotonin and brain derived neurotrophic factor
    Clement Hamani
    Neuroimaging Research Section, Centre for Addiction and Mental Health, Toronto Western Hospital, 250 College Street, Toronto, Ontario, Canada
    Biol Psychiatry 71:30-5. 2012
    ..We have studied the effects of ventromedial prefrontal cortex (vmPFC) stimulation in a chronic model of depression and assessed the involvement of the serotonergic system and brain derived neurotrophic factor (BDNF) in a DBS response...
  7. doi request reprint Bilateral anterior thalamic nucleus lesions are not protective against seizures in chronic pilocarpine epileptic rats
    Clement Hamani
    Departamentode Fisiologia, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Stereotact Funct Neurosurg 87:143-7. 2009
    ..To investigate whether anterior thalamic nucleus (AN) lesions are protective against spontaneous recurrent seizures in the chronic phase of the pilocarpine model of epilepsy...
  8. pmc Effects of anterior thalamic nucleus deep brain stimulation in chronic epileptic rats
    Luciene Covolan
    Disciplina de Neurofisiologia, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    PLoS ONE 9:e97618. 2014
    ..In contrast, a higher spike amplitude was recorded in slices from animals given AN DBS at 500 µA. ..
  9. ncbi request reprint Deep brain stimulation of the anterior nucleus of the thalamus: effects of electrical stimulation on pilocarpine-induced seizures and status epilepticus
    Clement Hamani
    Division of Neurosurgery, Toronto Western Hospital and University Health Network, University of Toronto, Toronto, Ontario, Canada
    Epilepsy Res 78:117-23. 2008
    ..As the optimal stimulation settings remain elusive, we studied the effects of different stimulation parameters against pilocarpine induced seizures and status epilepticus (SE)...
  10. ncbi request reprint Spontaneous recurrent seizures and neuropathology in the chronic phase of the pilocarpine and picrotoxin model epilepsy
    Clement Hamani
    Department of Physiology, UNIFESP EPM, R Botucatu 862, 04023 062 São Paulo SP, Brazil
    Neurol Res 24:199-209. 2002
    ..Future experiments conducted in this sense, might lead to important results in regard to the elucidation of mechanisms of epileptogenesis...
  11. ncbi request reprint Bilateral anterior thalamic nucleus lesions and high-frequency stimulation are protective against pilocarpine-induced seizures and status epilepticus
    Clement Hamani
    Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada
    Neurosurgery 54:191-5; discussion 195-7. 2004
    ..The aim of the present study was to investigate the influence of anterior thalamic nucleus lesions and high-frequency stimulation in the pilocarpine model of secondarily generalized seizures in rats...
  12. ncbi request reprint The motor thalamus in neurosurgery
    Clement Hamani
    Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
    Neurosurgery 58:146-58; discussion 146-58. 2006
    ..The aim of the present article is to briefly review the major anatomic and physiological aspects of the motor thalamus as well as the electrophysiological findings described in humans undergoing surgical procedures...
  13. ncbi request reprint Special lecture: Brain stimulation: perspectives for the future
    Clement Hamani
    Division of Neurosurgery, Toronto Western Hospital, Ontario, Canada
    Clin Neurosurg 51:271-4. 2004
  14. ncbi request reprint Tremor cells in the human thalamus: differences among neurological disorders
    Jason A Brodkey
    Division of Neurosurgery, Toronto Western Hospital, Ontario, Canada
    J Neurosurg 101:43-7. 2004
    ....
  15. ncbi request reprint Cingulotomy for psychiatric disease: microelectrode guidance, a callosal reference system for documenting lesion location, and clinical results
    Erich O Richter
    Department of Neurosurgery, University of Florida, Gainesville, Florida, USA
    Neurosurgery 54:622-28; discussion 628-30. 2004
    ....
  16. ncbi request reprint Physiology and pathophysiology of Parkinson's disease
    Clement Hamani
    Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
    Ann N Y Acad Sci 991:15-21. 2003
    ..With this abnormal neuronal activity neutralized, normal movements can in many cases be restored...
  17. ncbi request reprint Correspondence of microelectrode mapping with magnetic resonance imaging for subthalamic nucleus procedures
    Clement Hamani
    Division of Neurosurgery, University of Toronto, Toronto, ON M5T 2S8, Canada
    Surg Neurol 63:249-53; discussion 253. 2005
    ..Little is known about the correlation between the position of the STN as seen on MRI and that as determined by MER mapping. We compared these in 10 patients with Parkinson's disease...