Martin Blomberg Jensen

Summary

Publications

  1. doi Vitamin D deficiency and low ionized calcium are linked with semen quality and sex steroid levels in infertile men
    Martin Blomberg Jensen
    Department of Growth and Reproduction and International Research and Research Training Centre in Endocrine Disruption of Male Reproduction and Child Health EDMaRC, Rigshospitalet, Faculty of Medical and Health Sciences, University of Copenhagen, Blegdamsvej 9, Copenhagen DK 2100, Denmark Division of Bone and Mineral Research, Harvard School of Dental Medicine, Boston, MA, USA
    Hum Reprod 31:1875-85. 2016
  2. doi Characterization of the testicular, epididymal and endocrine phenotypes in the Leuven Vdr-deficient mouse model: targeting estrogen signalling
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark
    Mol Cell Endocrinol 377:93-102. 2013
  3. pmc Vitamin D metabolism and effects on pluripotency genes and cell differentiation in testicular germ cell tumors in vitro and in vivo
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark
    Neoplasia 14:952-63. 2012
  4. doi Non-genomic effects of vitamin D in human spermatozoa
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark
    Steroids 77:903-9. 2012
  5. doi Vitamin D metabolism, sex hormones, and male reproductive function
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Section 5064, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Reproduction 144:135-52. 2012
  6. doi Vitamin D is positively associated with sperm motility and increases intracellular calcium in human spermatozoa
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Section 5064, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Hum Reprod 26:1307-17. 2011
  7. doi Association of the polymorphism of the CAG repeat in the mitochondrial DNA polymerase gamma gene (POLG) with testicular germ-cell cancer
    M Blomberg Jensen
    Department of Growth and Reproduction, Rigshospitalet, Blegdamsvej, Copenhagen, Denmark
    Ann Oncol 19:1910-4. 2008
  8. doi Vitamin D receptor and vitamin D metabolizing enzymes are expressed in the human male reproductive tract
    Martin Blomberg Jensen
    University Department of Growth and Reproduction GR, Rigshospitalet Section 5064, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Hum Reprod 25:1303-11. 2010
  9. doi Expression of the vitamin D receptor, 25-hydroxylases, 1alpha-hydroxylase and 24-hydroxylase in the human kidney and renal clear cell cancer
    Martin Blomberg Jensen
    Department of Growth and Reproduction, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Denmark
    J Steroid Biochem Mol Biol 121:376-82. 2010
  10. doi Psychological stress and testicular function: a cross-sectional study of 1,215 Danish men
    Loa Nordkap
    University Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark
    Fertil Steril 105:174-87.e1-2. 2016

Detail Information

Publications22

  1. doi Vitamin D deficiency and low ionized calcium are linked with semen quality and sex steroid levels in infertile men
    Martin Blomberg Jensen
    Department of Growth and Reproduction and International Research and Research Training Centre in Endocrine Disruption of Male Reproduction and Child Health EDMaRC, Rigshospitalet, Faculty of Medical and Health Sciences, University of Copenhagen, Blegdamsvej 9, Copenhagen DK 2100, Denmark Division of Bone and Mineral Research, Harvard School of Dental Medicine, Boston, MA, USA
    Hum Reprod 31:1875-85. 2016
    ..Are low vitamin D levels linked with semen quality and sex steroids in infertile men?..
  2. doi Characterization of the testicular, epididymal and endocrine phenotypes in the Leuven Vdr-deficient mouse model: targeting estrogen signalling
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark
    Mol Cell Endocrinol 377:93-102. 2013
    ..In conclusion, vitamin D seems dispensable for murine spermatogenesis and sex hormone production, but aberrant estrogen-signalling may elicit some of the VDR-mediated effects on male reproduction...
  3. pmc Vitamin D metabolism and effects on pluripotency genes and cell differentiation in testicular germ cell tumors in vitro and in vivo
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark
    Neoplasia 14:952-63. 2012
    ....
  4. doi Non-genomic effects of vitamin D in human spermatozoa
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark
    Steroids 77:903-9. 2012
    ..A functional role of the VD-mediated Ca(2+) increase was supported by showing that 1,25(OH)(2)D(3) increased sperm motility and induced the acrosome reaction in vitro...
  5. doi Vitamin D metabolism, sex hormones, and male reproductive function
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Section 5064, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Reproduction 144:135-52. 2012
    ..The reviewed evidence suggests some effects of VD on estrogen and testosterone biosynthesis and implicates involvement of both systemic and local VD metabolism in the regulation of male fertility potential...
  6. doi Vitamin D is positively associated with sperm motility and increases intracellular calcium in human spermatozoa
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Section 5064, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Hum Reprod 26:1307-17. 2011
    ..We investigated the role of activated VD (1,25(OH)(2)D(3)) in human spermatozoa and whether VD serum levels are associated with semen quality...
  7. doi Association of the polymorphism of the CAG repeat in the mitochondrial DNA polymerase gamma gene (POLG) with testicular germ-cell cancer
    M Blomberg Jensen
    Department of Growth and Reproduction, Rigshospitalet, Blegdamsvej, Copenhagen, Denmark
    Ann Oncol 19:1910-4. 2008
    ....
  8. doi Vitamin D receptor and vitamin D metabolizing enzymes are expressed in the human male reproductive tract
    Martin Blomberg Jensen
    University Department of Growth and Reproduction GR, Rigshospitalet Section 5064, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Hum Reprod 25:1303-11. 2010
    ..Therefore, we performed a comprehensive analysis of the expression of VDR, VD activating (CYP2R1, CYP27A1, CYP27B1) and inactivating (CYP24A1) enzymes in the testis, epididymis, seminal vesicle (SV), prostate and spermatozoa...
  9. doi Expression of the vitamin D receptor, 25-hydroxylases, 1alpha-hydroxylase and 24-hydroxylase in the human kidney and renal clear cell cancer
    Martin Blomberg Jensen
    Department of Growth and Reproduction, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Denmark
    J Steroid Biochem Mol Biol 121:376-82. 2010
    ....
  10. doi Psychological stress and testicular function: a cross-sectional study of 1,215 Danish men
    Loa Nordkap
    University Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark
    Fertil Steril 105:174-87.e1-2. 2016
    ..To study the associations between self-reported psychological stress, semen quality, and serum reproductive hormones among young Danish men...
  11. doi PFOS (perfluorooctanesulfonate) in serum is negatively associated with testosterone levels, but not with semen quality, in healthy men
    Ulla Nordström Joensen
    University Department of Growth and Reproduction, Rigshospitalet, Section 5064, Blegdamsvej 9, Copenhagen DK 2100, Denmark
    Hum Reprod 28:599-608. 2013
    ..Is exposure to perfluorinated compounds (PFCs) associated with testicular function (reproductive hormone levels and semen quality) in healthy men?..
  12. doi Influence of vitamin D on cisplatin sensitivity in testicular germ cell cancer-derived cell lines and in a NTera2 xenograft model
    Anne Jørgensen
    Department of Growth and Reproduction, Rigshospitalet, Faculty of Health Science, University of Copenhagen, Denmark
    J Steroid Biochem Mol Biol 136:238-46. 2013
    ..This article is part of a Special Issue entitled 'Vitamin D Workshop'...
  13. pmc Phthalate excretion pattern and testicular function: a study of 881 healthy Danish men
    Ulla Nordström Joensen
    Department of Growth and Reproduction, Copenhagen University Hospital, Copenhagen, Denmark
    Environ Health Perspect 120:1397-403. 2012
    ..In animals, some phthalates impair male reproductive development and function. Epidemiological studies have reported inconsistent evidence of associations between phthalates and markers of human testicular function...
  14. doi Regional differences and temporal trends in male reproductive health disorders: semen quality may be a sensitive marker of environmental exposures
    Loa Nordkap
    University Department of Growth and Reproduction, Rigshospitalet, Section 5064, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Mol Cell Endocrinol 355:221-30. 2012
    ....
  15. doi Analysis of meiosis regulators in human gonads: a sexually dimorphic spatio-temporal expression pattern suggests involvement of DMRT1 in meiotic entry
    Anne Jørgensen
    Department of Growth and Reproduction, University of Copenhagen, Blegdamsvej 9, Copenhagen DK 2100, Denmark
    Mol Hum Reprod 18:523-34. 2012
    ..The biological importance of the changes in expression of DMRT1 in Sertoli cells remains to be established, but it is consistent with DMRT1 reinforcing the inhibition of meiosis in the testis...
  16. doi Vitamin D and male reproduction
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Section 5064, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Nat Rev Endocrinol 10:175-86. 2014
    ..Future studies are needed to determine when 1α,25-dihydroxyvitamin D acts in a paracrine manner and whether systemic changes, which are subject to pharmacological modulation, could influence male reproductive function. ..
  17. ncbi [Antioxidants and male subfertility--a survey of a Cochrane review]
    Tina Kold Jensen
    Klinik for Vækst og Reproduktion, Rigshospitalet, Blegdamsvej 9, 2100 København Ø, Denmark
    Ugeskr Laeger 173:3253-5. 2011
    ..Future studies should be large, randomized placebo-controlled trials...
  18. pmc Temporal Trends in Fertility Rates: A Nationwide Registry Based Study from 1901 to 2014
    Martin Blomberg Jensen
    Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA, United States of America
    PLoS ONE 10:e0143722. 2015
    ..Our objective is to determine whether women above thirty years of age historically have been able to sustain fertility rates above replacement level...
  19. doi Varicocele Is Associated with Impaired Semen Quality and Reproductive Hormone Levels: A Study of 7035 Healthy Young Men from Six European Countries
    Jakob Damsgaard
    University Department of Growth and Reproduction, Rigshospitalet, and International Research and Research Training Centre in Endocrine Disruption of Male Reproduction and Child Health EDMaRC, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    Eur Urol 70:1019-1029. 2016
    ..Present knowledge on the impact of varicoceles on testicular function is largely based on studies of subfertile and infertile men, making it difficult to extrapolate the impact of varicocele on the general population...
  20. doi Evaluation of 451 Danish boys with delayed puberty: diagnostic use of a new puberty nomogram and effects of oral testosterone therapy
    Jacob Gerner Lawaetz
    Department of Growth and Reproduction and EDMaRC J G L, C P H, M G M, M B J, A J, Rigshospitalet, University of Copenhagen, Denmark Department of Biostatistics J H P, University of Copenhagen, Denmark
    J Clin Endocrinol Metab 100:1376-85. 2015
    ..Few data exist on the diagnostic criteria, and on the effects of puberty induction, in boys with constitutional delay in growth and puberty (CDGP)...
  21. doi High dietary intake of saturated fat is associated with reduced semen quality among 701 young Danish men from the general population
    Tina K Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark
    Am J Clin Nutr 97:411-8. 2013
    ..Saturated fat intake has been associated with both cardiovascular disease and cancer risk, and a newly published study found an association between saturated fat intake and a lower sperm concentration in infertile men...
  22. doi Possible influence of vitamin D on male reproduction
    Ida Marie Boisen
    University Department of Growth and Reproduction and International Research and Research Training Centre in Endocrine Disruption of Male Reproduction and Child Health EDMaRC, Rigshospitalet, Faculty of Medical and Health Sciences, University of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen, Denmark Division of Bone and Mineral Research, Harvard School of Dental Medicine, Boston, MA, USA
    J Steroid Biochem Mol Biol . 2016
    ..In this review known and possible future implications of vitamin D in human male reproduction function will be discussed...