Sergio Romero

Summary

Affiliation: Vrije Universiteit Brussel
Country: Belgium

Publications

  1. doi request reprint Unaltered imprinting establishment of key imprinted genes in mouse oocytes after in vitro follicle culture under variable follicle-stimulating hormone exposure
    Ellen Anckaert
    Follicle Biology Laboratory, Universitair Ziekenhuis Brussel, Laarbeeklaan 101, Brussels 1090, Belgium
    Int J Dev Biol 53:541-8. 2009
  2. doi request reprint Improvement of in vitro culture of mouse cumulus-oocyte complexes using PDE3-inhibitor followed by meiosis induction with epiregulin
    Sergio Romero
    Follicle Biology Laboratory, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium
    Fertil Steril 93:936-44. 2010
  3. doi request reprint Epiregulin can effectively mature isolated cumulus-oocyte complexes, but fails as a substitute for the hCG/epidermal growth factor stimulus on cultured follicles
    Sergio Romero
    Follicle Biology Laboratory FOBI, Vrije Universiteit Brussel VUB, UZ Brussel, Brussels, Belgium
    Reproduction 137:997-1005. 2009
  4. doi request reprint Mouse cumulus-oocyte complexes from in vitro-cultured preantral follicles suggest an anti-luteinizing role for the EGF cascade in the cumulus cells
    Sergio Romero
    Follicle Biology Laboratory, Vrije Universiteit Brussel, Belgium
    Biol Reprod 84:1164-70. 2011
  5. doi request reprint Exposing cultured mouse ovarian follicles under increased gonadotropin tonus to aromatizable androgens influences the steroid balance and reduces oocyte meiotic capacity
    Sergio Romero
    Follicle Biology Laboratory FOBI, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium
    Endocrine 38:243-53. 2010
  6. doi request reprint Effects of low methyl donor levels in culture medium during mouse follicle culture on oocyte imprinting establishment
    Ellen Anckaert
    Follicle Biology Laboratory, Universitair Ziekenhuis Brussel, Brussels, Belgium
    Biol Reprod 83:377-86. 2010
  7. doi request reprint Ammonium accumulation and use of mineral oil overlay do not alter imprinting establishment at three key imprinted genes in mouse oocytes grown and matured in a long-term follicle culture
    Ellen Anckaert
    Follicle Biology Laboratory, Universitair Ziekenhuis Brussel, Brussels, Belgium
    Biol Reprod 81:666-73. 2009
  8. doi request reprint Oocyte and cumulus cell transcripts from cultured mouse follicles are induced to deviate from normal in vivo conditions by combinations of insulin, follicle-stimulating hormone, and human chorionic gonadotropin
    Flor Sánchez
    Follicle Biology Laboratory, Vrije Universiteit Brussel, Brussels, Belgium
    Biol Reprod 85:565-74. 2011
  9. doi request reprint Quantification of oocyte-specific transcripts in follicle-enclosed oocytes during antral development and maturation in vitro
    Flor Sánchez
    Follicle Biology Laboratory, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium
    Mol Hum Reprod 15:539-50. 2009
  10. doi request reprint Different follicle-stimulating hormone exposure regimens during antral follicle growth alter gene expression in the cumulus-oocyte complex in mice
    Flor Sánchez
    Follicle Biology Laboratory, Vrije Universiteit Brussel, Brussels, Belgium
    Biol Reprod 83:514-24. 2010

Detail Information

Publications12

  1. doi request reprint Unaltered imprinting establishment of key imprinted genes in mouse oocytes after in vitro follicle culture under variable follicle-stimulating hormone exposure
    Ellen Anckaert
    Follicle Biology Laboratory, Universitair Ziekenhuis Brussel, Laarbeeklaan 101, Brussels 1090, Belgium
    Int J Dev Biol 53:541-8. 2009
    ....
  2. doi request reprint Improvement of in vitro culture of mouse cumulus-oocyte complexes using PDE3-inhibitor followed by meiosis induction with epiregulin
    Sergio Romero
    Follicle Biology Laboratory, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium
    Fertil Steril 93:936-44. 2010
    ..To explore potential helping effects of a PDE3-inhibitor (PDE3-I), Org9935, in long-term culture of cumulus-corona-oocyte complexes (COC) and to associate adequate stimuli for efficient oocyte maturation...
  3. doi request reprint Epiregulin can effectively mature isolated cumulus-oocyte complexes, but fails as a substitute for the hCG/epidermal growth factor stimulus on cultured follicles
    Sergio Romero
    Follicle Biology Laboratory FOBI, Vrije Universiteit Brussel VUB, UZ Brussel, Brussels, Belgium
    Reproduction 137:997-1005. 2009
    ..By contrast, epiregulin is as efficient as hCG/EGF, when used as meiotic stimulator for COCs isolated from the follicular environment (mural granulosa and theca cells; and conditioned medium)...
  4. doi request reprint Mouse cumulus-oocyte complexes from in vitro-cultured preantral follicles suggest an anti-luteinizing role for the EGF cascade in the cumulus cells
    Sergio Romero
    Follicle Biology Laboratory, Vrije Universiteit Brussel, Belgium
    Biol Reprod 84:1164-70. 2011
    ..Therefore, it is proposed that within this in vitro mouse model, EGF signaling during ovulation might protect the cumulus cells from the potential luteinizing effects of LH...
  5. doi request reprint Exposing cultured mouse ovarian follicles under increased gonadotropin tonus to aromatizable androgens influences the steroid balance and reduces oocyte meiotic capacity
    Sergio Romero
    Follicle Biology Laboratory FOBI, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium
    Endocrine 38:243-53. 2010
    ..Follicles exposed to a combination of 25 mIU/ml FSH and 3 mIU/ml hCG and elevated aromatizable androgens altered the steroid production profile, affected the follicular development and impaired oocyte meiotic competence...
  6. doi request reprint Effects of low methyl donor levels in culture medium during mouse follicle culture on oocyte imprinting establishment
    Ellen Anckaert
    Follicle Biology Laboratory, Universitair Ziekenhuis Brussel, Brussels, Belgium
    Biol Reprod 83:377-86. 2010
    ....
  7. doi request reprint Ammonium accumulation and use of mineral oil overlay do not alter imprinting establishment at three key imprinted genes in mouse oocytes grown and matured in a long-term follicle culture
    Ellen Anckaert
    Follicle Biology Laboratory, Universitair Ziekenhuis Brussel, Brussels, Belgium
    Biol Reprod 81:666-73. 2009
    ..In the current culture setup, ammonium accumulation and mineral oil overlay during follicle culture do not induce aberrant imprinting establishment at the studied regulatory sequences in mouse oocytes...
  8. doi request reprint Oocyte and cumulus cell transcripts from cultured mouse follicles are induced to deviate from normal in vivo conditions by combinations of insulin, follicle-stimulating hormone, and human chorionic gonadotropin
    Flor Sánchez
    Follicle Biology Laboratory, Vrije Universiteit Brussel, Brussels, Belgium
    Biol Reprod 85:565-74. 2011
    ..These results demonstrate that in an in vitro follicle culture, a near physiological insulin background yields oocyte and cumulus cell transcript levels that are more similar to those in vivo...
  9. doi request reprint Quantification of oocyte-specific transcripts in follicle-enclosed oocytes during antral development and maturation in vitro
    Flor Sánchez
    Follicle Biology Laboratory, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium
    Mol Hum Reprod 15:539-50. 2009
    ..Moreover, they also show that meiotically competent oocytes kept in a prolonged transcriptionally inactive stage express altered levels of key transcripts compared with in vivo in both immature and mature oocytes...
  10. doi request reprint Different follicle-stimulating hormone exposure regimens during antral follicle growth alter gene expression in the cumulus-oocyte complex in mice
    Flor Sánchez
    Follicle Biology Laboratory, Vrije Universiteit Brussel, Brussels, Belgium
    Biol Reprod 83:514-24. 2010
    ..Conversely, a decrease in FSH does not affect transcript levels but seems to limit inappropriate Lhcgr expression. Modulating FSH within physiological ranges during the antral phase of culture alters cumulus cell differentiation...
  11. pmc In vitro follicle growth under non-attachment conditions and decreased FSH levels reduces Lhcgr expression in cumulus cells and promotes oocyte developmental competence
    Flor Sánchez
    Follicle Biology Laboratory FOBI, Vrije Universiteit Brussel, Laarbeeklaan, Brussels, Belgium
    J Assist Reprod Genet 29:141-52. 2012
    ..Effects of culturing under non-attachment conditions and varying follicle exposure to FSH were investigated at the mRNA level and on oocyte developmental capacity...
  12. ncbi request reprint Immature Oocytes from Unprimed Juvenile Mice Become a Valuable Source for Embryo Production When Using C-Type Natriuretic Peptide as Essential Component of Culture Medium
    Sergio Romero
    Follicle Biology Laboratory, Vrije Universiteit Brussel, Brussels, Belgium
    Biol Reprod 95:64. 2016
    ....