Pierre Francois Laterre

Summary

Country: Belgium

Publications

  1. ncbi request reprint Antimicrobial therapy for intra-abdominal infections: guidelines from the Infectious Disease Advisory Board (IDAB)
    P F Laterre
    Department of Critical Care Medicine, St Luc University Hospital, Brussels, Belgium
    Acta Chir Belg 106:2-21. 2006
  2. ncbi request reprint Pharmacological inhibition of tissue factor
    Pierre Francois Laterre
    Department of Critical Care Medicine, St Luc University Hospital, Université Catholigue de Louvan, Brussels, Belgium
    Semin Thromb Hemost 32:71-6. 2006
  3. ncbi request reprint International integrated database for the evaluation of severe sepsis and drotrecogin alfa (activated) therapy: 28-day survival and safety
    Pierre Francois Laterre
    Department of Critical Care Medicine, Hôpital St Luc, Universite Catholique de Louvain, B 1200 Brussels, Belgium
    J Crit Care 22:142-52. 2007
  4. pmc Multinational, observational study of procalcitonin in ICU patients with pneumonia requiring mechanical ventilation: a multicenter observational study
    Frank Bloos
    Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Erlanger Allee 101, 07747 Jena, Germany
    Crit Care 15:R88. 2011
  5. pmc Steroid use in PROWESS severe sepsis patients treated with drotrecogin alfa (activated)
    Howard Levy
    Acute Care, Eli Lilly and Co, Indianapolis, Indiana, USA
    Crit Care 9:R502-7. 2005
  6. pmc Clinical trials in severe sepsis with drotrecogin alfa (activated)
    Pierre Francois Laterre
    Department of Critical Care Medicine, St Luc University Hospital, Universite Catholique de Louvain, Avenue Hippocrate, 1200 Brussels, Belgium
    Crit Care 11:S5. 2007
  7. pmc A clinical evaluation committee assessment of recombinant human tissue factor pathway inhibitor (tifacogin) in patients with severe community-acquired pneumonia
    Pierre Francois Laterre
    St Luc University Hospital, Universite Catholique de Louvain, Avenue Hippocrate 10, 1200 Brussels, Belgium
    Crit Care 13:R36. 2009
  8. pmc Influence of enrollment sequence effect on observed outcomes in the ADDRESS and PROWESS studies of drotrecogin alfa (activated) in patients with severe sepsis
    Pierre Francois Laterre
    St Luc University Hospital, Avenue Hippocrate 10, 1200 Brussels, Belgium
    Crit Care 12:R117. 2008
  9. ncbi request reprint Intravenous omeprazole in critically ill patients: a randomized, crossover study comparing 40 with 80 mg plus 8 mg/hour on intragastric pH
    P F Laterre
    Department of Critical Care Medicine, Cliniques Universitaires St Luc, Brussels, Belgium
    Crit Care Med 29:1931-5. 2001
  10. pmc Clinical review: Drotrecogin alfa (activated) as adjunctive therapy for severe sepsis--practical aspects at the bedside and patient identification
    Pierre Francois Laterre
    Department of Critical Care and Emergency Medicine, St Luc University Hospital, Brussels, Belgium
    Crit Care 7:445-50. 2003

Collaborators

Detail Information

Publications44

  1. ncbi request reprint Antimicrobial therapy for intra-abdominal infections: guidelines from the Infectious Disease Advisory Board (IDAB)
    P F Laterre
    Department of Critical Care Medicine, St Luc University Hospital, Brussels, Belgium
    Acta Chir Belg 106:2-21. 2006
    ..Empiric antimicrobial therapy for the most common causes of abdominal infections is proposed. In addition, particular attention has been paid on antibiotic treatment duration...
  2. ncbi request reprint Pharmacological inhibition of tissue factor
    Pierre Francois Laterre
    Department of Critical Care Medicine, St Luc University Hospital, Université Catholigue de Louvan, Brussels, Belgium
    Semin Thromb Hemost 32:71-6. 2006
    ..Even though they are not associated with an improved outcome, the observed data support further clinical studies...
  3. ncbi request reprint International integrated database for the evaluation of severe sepsis and drotrecogin alfa (activated) therapy: 28-day survival and safety
    Pierre Francois Laterre
    Department of Critical Care Medicine, Hôpital St Luc, Universite Catholique de Louvain, B 1200 Brussels, Belgium
    J Crit Care 22:142-52. 2007
    ..Initial analyses evaluated the 28-day survival in the placebo group and further assessed the treatment effect of drotrecogin alfa (activated) (DrotAA)...
  4. pmc Multinational, observational study of procalcitonin in ICU patients with pneumonia requiring mechanical ventilation: a multicenter observational study
    Frank Bloos
    Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Erlanger Allee 101, 07747 Jena, Germany
    Crit Care 15:R88. 2011
    ..The intent of this study was to determine whether serum procalcitonin (PCT) levels are associated with prognosis, measured as organ dysfunctions and 28-day mortality, in patients with severe pneumonia...
  5. pmc Steroid use in PROWESS severe sepsis patients treated with drotrecogin alfa (activated)
    Howard Levy
    Acute Care, Eli Lilly and Co, Indianapolis, Indiana, USA
    Crit Care 9:R502-7. 2005
    ..The present study examines intravenous steroid use in PROWESS (Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis) patients meeting the Annane enrollment criteria (AEC)...
  6. pmc Clinical trials in severe sepsis with drotrecogin alfa (activated)
    Pierre Francois Laterre
    Department of Critical Care Medicine, St Luc University Hospital, Universite Catholique de Louvain, Avenue Hippocrate, 1200 Brussels, Belgium
    Crit Care 11:S5. 2007
    ..This review discusses all large clinical trials exploring the efficacy and safety of DrotAA and proposes recommendations for the use of DrotAA in severe sepsis...
  7. pmc A clinical evaluation committee assessment of recombinant human tissue factor pathway inhibitor (tifacogin) in patients with severe community-acquired pneumonia
    Pierre Francois Laterre
    St Luc University Hospital, Universite Catholique de Louvain, Avenue Hippocrate 10, 1200 Brussels, Belgium
    Crit Care 13:R36. 2009
    ....
  8. pmc Influence of enrollment sequence effect on observed outcomes in the ADDRESS and PROWESS studies of drotrecogin alfa (activated) in patients with severe sepsis
    Pierre Francois Laterre
    St Luc University Hospital, Avenue Hippocrate 10, 1200 Brussels, Belgium
    Crit Care 12:R117. 2008
    ....
  9. ncbi request reprint Intravenous omeprazole in critically ill patients: a randomized, crossover study comparing 40 with 80 mg plus 8 mg/hour on intragastric pH
    P F Laterre
    Department of Critical Care Medicine, Cliniques Universitaires St Luc, Brussels, Belgium
    Crit Care Med 29:1931-5. 2001
    ..To compare intravenous omeprazole 40-mg single dose with 8 mg/hr after an 80-mg bolus injection on 24-hr intragastric pH in intensive care unit (ICU) ventilated patients...
  10. pmc Clinical review: Drotrecogin alfa (activated) as adjunctive therapy for severe sepsis--practical aspects at the bedside and patient identification
    Pierre Francois Laterre
    Department of Critical Care and Emergency Medicine, St Luc University Hospital, Brussels, Belgium
    Crit Care 7:445-50. 2003
    ..Finally, the type and source of infection, and its anticipated natural history, may determine whether drotrecogin alfa (activated) is indicated as well as the timing of its administration...
  11. ncbi request reprint Management of patients with severe sepsis, treated by drotrecogin alfa (activated)
    Pierre Francois Laterre
    Department of Critical Care Medicine, Saint Luc University Hospital Louvain Medical School, 10 Avenue Hippocrate, 1200 Brussels, Belgium
    Am J Surg 184:S39-46. 2002
    ..Proper adherence to principles described in this article can facilitate patient management and reduce the risk of bleeding...
  12. doi request reprint Progress in medical management of intra-abdominal infection
    Pierre Francois Laterre
    Department of Critical Care Medicine, St Luc University Hospital, Catholic University of Louvain, Brussels, Belgium
    Curr Opin Infect Dis 21:393-8. 2008
    ..This review focuses on recent studies on antibiotic therapy for intra-abdominal infections and in particular for the management of severe acute pancreatitis...
  13. ncbi request reprint Hospital mortality and resource use in subgroups of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis (PROWESS) trial
    Pierre Francois Laterre
    Department of Critical Care, St Luc University Hospital, UCL, Brussels, Belgium
    Crit Care Med 32:2207-18. 2004
    ..To compare differences in hospital mortality and resource use in adult severe sepsis subjects randomized to receive drotrecogin alfa (activated) (DrotAA) or placebo in the PROWESS trial...
  14. doi request reprint Empirical models for dosage optimization of four beta-lactams in critically ill septic patients based on therapeutic drug monitoring of amikacin
    Isabelle K Delattre
    Unit of Clinical Biochemistry, Universite Catholique de Louvain, Avenue Hippocrate, 10, B 1200 Brussels, Belgium
    Clin Biochem 43:589-98. 2010
    ..The study aims to develop empirical models able to predict the pharmacokinetics (PK) of four beta-lactams using the amikacin (AMK) therapeutic drug monitoring (TDM), in order to optimize their dosage regimens...
  15. doi request reprint Population pharmacokinetics of four β-lactams in critically ill septic patients comedicated with amikacin
    Isabelle K Delattre
    Louvain Centre for Toxicology and applied Pharmacology, Universite Catholique de Louvain, Brussels, Belgium
    Clin Biochem 45:780-6. 2012
    ....
  16. ncbi request reprint Severe community-acquired pneumonia as a cause of severe sepsis: data from the PROWESS study
    Pierre Francois Laterre
    Head of Intensive Care Unit, Cliniques Universitaires Saint Luc Service des Urgences et des Soins Intensifs, UCL, Brussels, Belgium
    Crit Care Med 33:952-61. 2005
    ....
  17. pmc Aerosol delivery with two ventilation modes during mechanical ventilation: a randomized study
    Jonathan Dugernier
    Soins Intensifs, Medecine Physique, Cliniques Universitaires Saint Luc, Avenue Hippocrate 10, 1200, Brussels, Belgium
    Ann Intensive Care 6:73. 2016
    ....
  18. doi request reprint Pharmacokinetics of a loading dose of amikacin in septic patients undergoing continuous renal replacement therapy
    Fabio Silvio Taccone
    Department of Intensive Care, Erasme Hospital, Brussels, Belgium
    Int J Antimicrob Agents 37:531-5. 2011
    ..The therapeutic benefit of high-dose aminoglycoside therapy should be balanced with its potential renal effects in septic patients receiving CRRT...
  19. ncbi request reprint ADDRESS (ADministration of DRotrecogin alfa [activated] in Early stage Severe Sepsis) long-term follow-up: one-year safety and efficacy evaluation
    Pierre Francois Laterre
    Department of Critical Care Medicine, St Luc University Hospital, UCL, Brussels, Belgium
    Crit Care Med 35:1457-63. 2007
    ..To demonstrate that drotrecogin alfa (activated) has an acceptable safety profile 1 yr from randomization...
  20. ncbi request reprint Prolonged unconsciousness in a patient on automated peritoneal dialysis
    Fernande Lois
    Department of Intensive Care, Cliniques St Luc, Universite Catholique de Louvain, Brussels, Belgium
    Eur J Emerg Med 13:361-3. 2006
    ..Baclofen is mainly excreted by the kidney. A short-term administration of low-dose of baclofen is not effectively removed by peritoneal dialysis and may result in prolonged but reversible coma...
  21. ncbi request reprint Anticoagulant therapy in acute lung injury
    Pierre Francois Laterre
    Medical Surgical Intensive Care Unit, St Luc University Hospital, Brussels, Belgium
    Crit Care Med 31:S329-36. 2003
    ..Soluble thrombomodulin has been shown to improve ALI in animals, and it is currently being evaluated in humans with sepsis. Finally, plasminogen activators may improve gas exchange in ALI, but studies in humans are limited...
  22. doi request reprint Evaluating the efficacy and safety of two doses of the polyclonal anti-tumor necrosis factor-α fragment antibody AZD9773 in adult patients with severe sepsis and/or septic shock: randomized, double-blind, placebo-controlled phase IIb study*
    Gordon R Bernard
    1Division of Pulmonary and Critical Care Medicine, Vanderbilt University, Nashville, TN 2Service de Réanimation Polyvalente, CIC P 0801, CHU Dupuytren, Limoges, Cedex, France 3Hôpitaux Paris Centre, AP HP Universite Paris Descartes, Faculte de Medecine, Paris, France and Cochin Institute, INSERM U567, CNRS UMR 8104, Paris, France 4Department of Intensive Care, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium 5Department of Medicine, Cooper University Hospital, Camden, NJ 6Centre for Heart Lung Innovation, University of British Columbia, Vancouver, BC, Canada 7Division of Infectious Diseases, Beverly Hospital, Beverly, MA 8Critical Care Department, St Luc University Hospital, Universite Catholique de Louvain, Brussels, Belgium 9Department of Medicine, Brown University, Providence, RI 10Worldwide Medical Services Department, PAREXEL International, Durham, NC 11AstraZeneca, Alderley Park, India
    Crit Care Med 42:504-11. 2014
    ..This trial compared the efficacy/safety of two IV doses of AZD9773, a polyclonal antibody to tumor necrosis factor-α, in adult patients with severe sepsis/septic shock...
  23. ncbi request reprint Re-use of a liver allograft; an exceptional opportunity to enlarge the organ donor pool
    Raphaël Rubay
    Department of Digestive Surgery, Cliniques Universitaires St Luc 1400, Universite Catholique de Louvain UCL, Av Hippocrate 10, 1200, Brussels, Belgium
    Transpl Int 16:497-9. 2003
    ..5 h later into a patient with post-viral C cirrhosis and solitary hepatocarcinoma. Both donor and recipient operations were technically successful; liver function after the second use of the graft was normal...
  24. pmc Teamwork enables high level of early mobilization in critically ill patients
    Cheryl Elizabeth Hickmann
    Intensive Care Unit, Cliniques Universitaires Saint Luc, Universite Catholique de Louvain UCL, Avenue Hippocrate 10, 1200, Brussels, Belgium
    Ann Intensive Care 6:80. 2016
    ..This study sought to demonstrate that early mobilization performed within the first 24 h of ICU admission proves to be feasible and well tolerated in the vast majority of critically ill patients...
  25. ncbi request reprint SPECT-CT Comparison of Lung Deposition using a System combining a Vibrating-mesh Nebulizer with a Valved Holding Chamber and a Conventional Jet Nebulizer: a Randomized Cross-over Study
    Jonathan Dugernier
    Institut de Recherche Expérimentale et Clinique IREC, Pneumologie, ORL and Dermatologie, Cliniques Universitaires Saint Luc, Avenue Hippocrate 10, 1200, Brussels, Belgium
    Pharm Res . 2016
    ....
  26. ncbi request reprint Lipopolysaccharide-binding protein serum levels in patients with severe sepsis due to gram-positive and fungal infections
    Laurent Blairon
    Department of Clinical Biology, St Luc University Hospital, Brussels, Belgium
    J Infect Dis 187:287-91. 2003
    ..Furthermore, in patients with multiple episodes of sepsis, LBP response seems to be of lesser magnitude after each subsequent episode of severe sepsis...
  27. ncbi request reprint A pilot-controlled study of a polymyxin B-immobilized hemoperfusion cartridge in patients with severe sepsis secondary to intra-abdominal infection
    Jean Louis Vincent
    Department of Intensive Care, Erasme Hospital, Free University of Brussels, Brussels, Belgium
    Shock 23:400-5. 2005
    ..Treatment using the PMX cartridge is safe and may improve cardiac and renal dysfunction due to sepsis or septic shock. Further studies are needed to prove this effectiveness...
  28. doi request reprint Influence of inspiratory flow pattern and nebulizer position on aerosol delivery with a vibrating-mesh nebulizer during invasive mechanical ventilation: an in vitro analysis
    Jonathan Dugernier
    1Intensive Care Unit, University Hospital Saint Luc, Brussels, Belgium
    J Aerosol Med Pulm Drug Deliv 28:229-36. 2015
    ....
  29. doi request reprint CT-proAVP IS NOT A GOOD PREDICTOR OF VASOPRESSOR NEED IN SEPTIC SHOCK
    Said Laribi
    APHP, Saint Louis Lariboisière Hospitals, Emergency Department INSERM U942, biomarkers in cardioneurovascular diseases, Paris, France Department of Critical Care Medicine, Cliniques Universitaires Saint Luc, Saint Luc University Hospital, Universite Catholique de Louvain, Brussels, Belgium
    Shock 44:330-5. 2015
    ..Another objective was to explore if plasma CT-proAVP (C terminal part of preprovasopressin) measured within 24 h of sepsis onset could predict patient severity...
  30. doi request reprint Connection between cardiac vascular permeability, myocardial edema, and inflammation during sepsis: role of the α1AMP-activated protein kinase isoform
    Diego Castanares-Zapatero
    1Pôle de Recherche Cardiovasculaire, Institut de Recherche Expérimentale et Clinique, Universite Catholique de Louvain, Brussels, Belgium 2Division of Intensive Care, Cliniques Universitaires Saint Luc, Brussels, Belgium 3Center for Interdisciplinary Research in Biology, INSERM U1050, CNRS UMR7241, College de France, Paris, France 4Division of Cardiology, Cliniques Universitaires Saint Luc, Brussels, Belgium 5Laboratory of Thrombosis and Hemostasis, GIGA Cardiovascular Sciences, University of Liege, Liege, Belgium 6Institute of Interdisciplinary Research in Human and Molecular Biology, Universite Libre de Bruxelles, Brussels, Belgium 7INSERM U1016, Institut Cochin, Paris, France 8CNRS, UMR8104, Paris, France 9Université Paris Descartes, Sorbonne Paris Cité, France
    Crit Care Med 41:e411-22. 2013
    ....
  31. ncbi request reprint Compartmentalization of the inflammatory response during acute pancreatitis: correlation with local and systemic complications
    Thierry L Dugernier
    Department of Intensive Care and Emergency Medicine, St Luc University Hospital, Hippocrate Avenue, 10 B 1200 Brussels, Belgium
    Am J Respir Crit Care Med 168:148-57. 2003
    ....
  32. pmc Beyond antibiotics in severe community-acquired pneumonia: the role and rationale for tissue factor pathway inhibition
    Pierre Francois Laterre
    St Luc University Hospital, Universite Catholique de Louvain, UCL, 1200 Brussels, Belgium
    Crit Care 12:S4. 2008
    ....
  33. doi request reprint Electrical vagus nerve stimulation and nicotine effects in peritonitis-induced acute lung injury in rats
    Claire Boland
    Department of Critical Care Medicine, Saint Luc University Hospital, Universite Catholique de Louvain, Brussels, Belgium
    Inflammation 34:29-35. 2011
    ..Nicotine-induced bacterial clearance impairment and nicotine systemic effects may explain these observations...
  34. pmc Early hyperlactatemia predicts pancreatic fistula after surgery
    Nicolas De Schryver
    Department of Critical Care Medicine, Cliniques Universitaires Saint Luc, Universite Catholique de Louvain UCL, Avenue Hippocrate 10, B 1200, Brussels, Belgium
    BMC Anesthesiol 15:109. 2015
    ..We aimed to determine in a retrospective high-volume center's cohort whether postoperative hyperlactatemia could predict POPF occurrence...
  35. doi request reprint Temocillin (6 g daily) in critically ill patients: continuous infusion versus three times daily administration
    Pierre Francois Laterre
    Department of Critical Care Medicine, St Luc University Hospital, Universite Catholique de Louvain, Brussels, Belgium
    J Antimicrob Chemother 70:891-8. 2015
    ....
  36. doi request reprint Energy expenditure in the critically ill performing early physical therapy
    Cheryl E Hickmann
    Department of Critical Care Medicine, Cliniques Universitaires Saint Luc, Saint Luc University Hospital, Universite Catholique de Louvain UCL, 10, Avenue Hippocrate, 1200, Brussels, Belgium
    Intensive Care Med 40:548-55. 2014
    ..We conducted an observational study to determine the impact of early exercise on energy requirements to adjust caloric intake accordingly in critically ill patients...
  37. ncbi request reprint Electrocardiographic changes after head trauma
    Xavier Wittebole
    Department of Intensive Care, University Hosital Saint Luc, Catholic University of Louvain, Brussels 1200, Belgium
    J Electrocardiol 38:77-81. 2005
    ..This kind of traumatic brain injury thus may be responsible for a pseudo-acute myocardial ischemic syndrome...
  38. ncbi request reprint Compartmentalization of the protease-antiprotease balance in early severe acute pancreatitis
    Thierry Dugernier
    Department of Intensive Care, St Luc University Hospital, Brussels, Belgium
    Pancreas 31:168-73. 2005
    ..To assess the balance between trypsin and protease inhibitors simultaneously in the systemic circulation and in the thoracic lymph and peritoneal exudate...
  39. doi request reprint Population pharmacokinetic modeling and optimal sampling strategy for Bayesian estimation of amikacin exposure in critically ill septic patients
    Isabelle K Delattre
    Louvain Centre for Toxicology and applied Pharmacology, Universite Catholique de Louvain, Brussels, Belgium
    Ther Drug Monit 32:749-56. 2010
    ..Based on the population estimates, an optimal sampling strategy suitable for Bayesian estimation of the drug PK parameters was developed, meeting the need of clinical practice...
  40. ncbi request reprint Traumatic injuries: imaging and intervention in post-traumatic complications (delayed intervention)
    Pierre P Goffette
    Department of Medical Imaging, Saint Luc University Hospital Louvain Medical School, 10, Avenue Hippocrate, 1200 Brussels, Belgium
    Eur Radiol 12:994-1021. 2002
    ..Treatment modalities of less common complications, such as bowel stricture or perforation, mesenteric vascular injuries and renal trauma-induced hypertension, are reviewed...
  41. ncbi request reprint Recurrent seizure and sustained encephalopathy associated with dimethylsulfoxide-preserved stem cell infusion
    Deborah Bauwens
    Department of Intensive Care, Cliniques St Luc, Universite Catholique de Louvain, Brussels, Belgium
    Leuk Lymphoma 46:1671-4. 2005
    ..Severe but reversible neurological complications may occur with the infusion of PBPCs cryopreserved with DMSO...
  42. ncbi request reprint Cavocaval adult liver transplantation and retransplantation without venovenous bypass and without portocaval shunting: a prospective feasibility study in adult liver transplantation
    Jan Lerut
    Department of Digestive Surgery, Liver Transplant Program, Cliniques Universitaires Saint Luc, Universite Catholique de Louvain, Brussels, Belgium
    Transplantation 75:1740-5. 2003
    ..Refinements in technique permit transplantation to be done with IVC preservation and without VVB use...
  43. ncbi request reprint Ruptured hydatid cyst in a patient with shock
    Diego Castanares-Zapatero
    Cliniques Universitaires Saint Luc, Universite Catholique de Louvain UCL, Department of Critical Care Medicine, Avenue Hippocrate, 10, 1200 Brussels, Belgium
    Hepatobiliary Pancreat Dis Int 8:638-9. 2009
    ..Moreover, we emphasize the need for a radical surgical approach to avoid widespread dissemination...