Frank Buntinx

Summary

Affiliation: Katholieke Universiteit Leuven
Country: Belgium

Publications

  1. pmc Serious infections in children: an incidence study in family practice
    Ann Van den Bruel
    Academisch Centrum voor Huisartsgeneeskunde, Katholieke Universiteit Leuven, Leuven, Belgium
    BMC Fam Pract 7:23. 2006
  2. pmc Conducting systematic reviews of diagnostic studies: didactic guidelines
    Walter L Deville
    Institute for Research in Extramural Medicine EMGO Institute, VU University Medical Centre, Amsterdam, The Netherlands
    BMC Med Res Methodol 2:9. 2002
  3. ncbi request reprint Evaluation of Charlson's comorbidity index in elderly living in nursing homes
    F Buntinx
    Department of General Practice KUL, Kapucijnenvoer 33, Blok J, B 3000 Leuven, Belgium
    J Clin Epidemiol 55:1144-7. 2002
  4. ncbi request reprint Geographical differences in cancer incidence in the Belgian province of Limburg
    F Buntinx
    Limburg Cancer Registry LIKAR, Limburgse Kankerstichting, Stadsomvaart 9, 3500, Hasselt, Belgium
    Eur J Cancer 39:2058-72. 2003
  5. pmc Is herpes zoster a marker for occult or subsequent malignancy?
    Frank Buntinx
    Department of General Practice, University of Leuven, Leuven, Belgium
    Br J Gen Pract 55:102-7. 2005
  6. pmc The incidence of stroke and transient ischaemic attacks is falling: a report from the Belgian sentinel stations
    Frank Buntinx
    Department of General Practice, Catholic University of Leuven, Belgium
    Br J Gen Pract 52:813-7. 2002
  7. ncbi request reprint Why does the general practitioner refer patients with chest pain not-urgently to the specialist or urgently to the emergency department? Influence of the certainty of the initial diagnosis
    Rudi Bruyninckx
    Department of General Practice, Katholieke Universiteit Leuven, Belgium
    Acta Cardiol 64:259-65. 2009
  8. pmc Dietary intake of micronutrients and the risk of developing bladder cancer: results from the Belgian case-control study on bladder cancer risk
    Maree T Brinkman
    Department of General Practice, Katholieke Universiteit Leuven, Comprehensive Cancer Institute Limburg LIKAS, Leuven, Belgium
    Cancer Causes Control 22:469-78. 2011
  9. ncbi request reprint Does occupational exposure to PAHs, diesel and aromatic amines interact with smoking and metabolic genetic polymorphisms to increase the risk on bladder cancer?; The Belgian case control study on bladder cancer risk
    Eliane Kellen
    Department of General Practice, Katholieke Universiteit Leuven, Comprehensive Cancer Institute Limburg, Belgium
    Cancer Lett 245:51-60. 2007
  10. pmc What is the role of the general practitioner towards the family caregiver of a community-dwelling demented relative? A systematic literature review
    Birgitte Schoenmakers
    Catholic University Leuven, Academic Centre of General Practice, Kapucijnenvoer 33, Leuven, Belgium
    Scand J Prim Health Care 27:31-40. 2009

Detail Information

Publications126 found, 100 shown here

  1. pmc Serious infections in children: an incidence study in family practice
    Ann Van den Bruel
    Academisch Centrum voor Huisartsgeneeskunde, Katholieke Universiteit Leuven, Leuven, Belgium
    BMC Fam Pract 7:23. 2006
    ..We therefore estimated the incidence of serious infections in general practice in Belgium...
  2. pmc Conducting systematic reviews of diagnostic studies: didactic guidelines
    Walter L Deville
    Institute for Research in Extramural Medicine EMGO Institute, VU University Medical Centre, Amsterdam, The Netherlands
    BMC Med Res Methodol 2:9. 2002
    ..Although guidelines for critical appraisal of diagnostic research and meta-analyses have already been published, these may be difficult to understand for clinical researchers or do not provide enough detailed information...
  3. ncbi request reprint Evaluation of Charlson's comorbidity index in elderly living in nursing homes
    F Buntinx
    Department of General Practice KUL, Kapucijnenvoer 33, Blok J, B 3000 Leuven, Belgium
    J Clin Epidemiol 55:1144-7. 2002
    ..These results support its use as a measure for introducing comorbidity as a covariable in longitudinal studies with a geriatric population...
  4. ncbi request reprint Geographical differences in cancer incidence in the Belgian province of Limburg
    F Buntinx
    Limburg Cancer Registry LIKAR, Limburgse Kankerstichting, Stadsomvaart 9, 3500, Hasselt, Belgium
    Eur J Cancer 39:2058-72. 2003
    ..A pre-emptive analysis of possible cancer incidence clustering on the municipality level proved to be feasible...
  5. pmc Is herpes zoster a marker for occult or subsequent malignancy?
    Frank Buntinx
    Department of General Practice, University of Leuven, Leuven, Belgium
    Br J Gen Pract 55:102-7. 2005
    ..It has been suggested that herpes zoster may be a marker for occult malignancy...
  6. pmc The incidence of stroke and transient ischaemic attacks is falling: a report from the Belgian sentinel stations
    Frank Buntinx
    Department of General Practice, Catholic University of Leuven, Belgium
    Br J Gen Pract 52:813-7. 2002
    ..Increasing as well as decreasing trends in stroke incidence have been described...
  7. ncbi request reprint Why does the general practitioner refer patients with chest pain not-urgently to the specialist or urgently to the emergency department? Influence of the certainty of the initial diagnosis
    Rudi Bruyninckx
    Department of General Practice, Katholieke Universiteit Leuven, Belgium
    Acta Cardiol 64:259-65. 2009
    ..Chest pain is an initial symptom for several minor diseases but acute myocardial infarction (AMI) should not be missed...
  8. pmc Dietary intake of micronutrients and the risk of developing bladder cancer: results from the Belgian case-control study on bladder cancer risk
    Maree T Brinkman
    Department of General Practice, Katholieke Universiteit Leuven, Comprehensive Cancer Institute Limburg LIKAS, Leuven, Belgium
    Cancer Causes Control 22:469-78. 2011
    ..We aimed to investigate the effect of dietary intake of micronutrients that are metabolized and excreted via the urinary tract on bladder cancer risk...
  9. ncbi request reprint Does occupational exposure to PAHs, diesel and aromatic amines interact with smoking and metabolic genetic polymorphisms to increase the risk on bladder cancer?; The Belgian case control study on bladder cancer risk
    Eliane Kellen
    Department of General Practice, Katholieke Universiteit Leuven, Comprehensive Cancer Institute Limburg, Belgium
    Cancer Lett 245:51-60. 2007
    ..We confirm that occupational exposure to aromatic amines is associated with an increase in bladder cancer risk...
  10. pmc What is the role of the general practitioner towards the family caregiver of a community-dwelling demented relative? A systematic literature review
    Birgitte Schoenmakers
    Catholic University Leuven, Academic Centre of General Practice, Kapucijnenvoer 33, Leuven, Belgium
    Scand J Prim Health Care 27:31-40. 2009
    ..To identify the attitudes and perspectives of the family physician towards the caregivers of demented relatives and to describe the caregivers' satisfaction...
  11. pmc Computerized general practice based networks yield comparable performance with sentinel data in monitoring epidemiological time-course of influenza-like illness and acute respiratory illness
    Carla Truyers
    Department of General Practice, Katholieke Universiteit Leuven, Leuven, Belgium
    BMC Fam Pract 11:24. 2010
    ..Computerized morbidity registration networks might serve as early warning systems in a time where natural epidemics such as the H1N1 flu can easily spread from one region to another...
  12. ncbi request reprint Quality assessment of oral anticoagulation in Belgium, as practiced by a group of general practitioners
    Neree Claes
    Department of General Practice, Catholic University Leuven, Belgium
    Acta Cardiol 60:247-52. 2005
    ..This study aims to evaluate the quality of management of oral anticoagulation by Belgian GPs and to verify the relation between time in range and a set of potentially influencing co-variables...
  13. doi request reprint Reduction in hormone replacement therapy use and declining breast cancer incidence in the Belgian province of Limburg
    Patrik Vankrunkelsven
    Department of General Practice, Katholieke Universiteit Leuven, Leuven, Belgium
    Breast Cancer Res Treat 118:425-32. 2009
    ..This suggests that HRT stimulates the growth of pre-existing, clinically latent tumours that may not otherwise become clinically apparent...
  14. doi request reprint Half of the patients with chest pain that are urgently referred are transported in unsafe conditions
    Rudi Bruyninckx
    Department of General Practice, ACHG KULeuven, Leuven, Belgium
    Eur J Emerg Med 15:330-3. 2008
    ..Owing to the risks of ventricular fibrillation and pulseless ventricular tachycardia, urgent transport should be organized under safe conditions, that is, with a defibrillator at hand...
  15. ncbi request reprint Blood cadmium may be associated with bladder carcinogenesis: the Belgian case-control study on bladder cancer
    Eliane Kellen
    Department of General Practice, Katholieke Universiteit Leuven, Comprehensive Cancer Institute Limburg, Belgium
    Cancer Detect Prev 31:77-82. 2007
    ..The aim of this study was to assess the relationship between exposure to cadmium and bladder cancer risk...
  16. pmc Signs and symptoms for diagnosis of serious infections in children: a prospective study in primary care
    Ann Van den Bruel
    Department of General Practice, Katholieke Universiteit and CEBAM, Belgian Centre for Evidence Based Medicine, Leuven, Belgium
    Br J Gen Pract 57:538-46. 2007
    ..In children with an acute illness, the primary care physician uses signs and symptoms to assess the probability of a serious infection and decide on further management...
  17. pmc Validation of the flemish CARES, a quality of life and needs assessment tool for cancer care
    Bojoura Schouten
    Faculty of Medicine and Life Sciences, Hasselt University, Martelarenlaan 42, 3500, Hasselt, Belgium
    BMC Cancer 16:696. 2016
    ..Since November 2012 the copyright and user fee were abolished and the instrument became publicly available the present study aims to reinvestigate the psychometric properties of the CARES for the Flemish population in Belgium...
  18. doi request reprint Phase III randomised chemoprevention study with selenium on the recurrence of non-invasive urothelial carcinoma. The SELEnium and BLAdder cancer Trial
    Maria E Goossens
    Department of General Practice, University of Leuven, ACHG KU Leuven, Kapucijnenvoer 33, Blok J, Bus 7001, 3000, Leuven, Belgium Electronic address
    Eur J Cancer 69:9-18. 2016
    ..Previous epidemiological studies have consistently reported that selenium concentrations were inversely associated with the risk of BC. We therefore hypothesised that selenium may be suitable for chemoprevention of recurrence of BC...
  19. doi request reprint Loneliness in patients with cancer: the first year after cancer diagnosis
    Laura Deckx
    Department of General Practice, KU Leuven, Leuven, Belgium
    Psychooncology 24:1521-8. 2015
    ..We evaluated if changes in common cancer-related and ageing-related problems such as fatigue, cognitive functioning and functional status contributed to the occurrence of loneliness...
  20. ncbi request reprint Occurrence of both bladder and prostate cancer in five cancer registries in Belgium, The Netherlands and the United Kingdom
    Eliane Kellen
    Department of General Practice, Katholieke Universiteit Leuven Comprehensive Cancer Institute Limburg, Belgium
    Eur J Cancer 43:1694-700. 2007
    ..To assess the occurrence of both bladder and prostate tumours in five well defined cancer registries...
  21. ncbi request reprint Tasks performance by registered nurses and care assistants in nursing homes: a quantitative comparison of survey data
    Louis Paquay
    Department of General Practice, Katholieke Universiteit Leuven, Leuven, Belgium
    Int J Nurs Stud 44:1459-67. 2007
    ....
  22. doi request reprint Qualitative research on the Belgian Cancer Rehabilitation Evaluation System (CARES): An evaluation of the content validity and feasibility
    Bojoura Schouten
    Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium
    J Eval Clin Pract . 2017
    ..This article describes Belgian patients' view on the content validity and feasibility of the CARES for use in current cancer care...
  23. pmc How well do clinical prediction rules perform in identifying serious infections in acutely ill children across an international network of ambulatory care datasets?
    Jan Y Verbakel
    Department of General Practice, KU Leuven, Kapucijnenvoer 33 Blok J, 3000 Leuven, Belgium
    BMC Med 11:10. 2013
    ..We aimed to examine the diagnostic accuracy of these rules in multiple ambulatory care populations in Europe...
  24. pmc Designing the selenium and bladder cancer trial (SELEBLAT), a phase lll randomized chemoprevention study with selenium on recurrence of bladder cancer in Belgium
    Maria E Goossens
    Department of General Practice, University of Leuven, ACHG KU Leuven, Kapucijnenvoer 33, Blok J, Bus 7001, 3000 Leuven, Belgium
    BMC Urol 12:8. 2012
    ..8%). Previous epidemiological studies have consistently reported that selenium concentrations were inversely associated with the risk of bladder cancer. This suggests that selenium may also be suitable for chemoprevention of recurrence...
  25. pmc Incident somatic comorbidity after psychosis: results from a retrospective cohort study based on Flemish general practice data
    Carla Truyers
    Department of General Practice, Katholieke Universiteit Leuven, Leuven, Belgium
    BMC Fam Pract 12:132. 2011
    ..Many studies are performed in specialized settings with a strong focus on schizophrenia. Somatic comorbidity after psychosis is studied, using a general practice comorbidity registration network...
  26. ncbi request reprint Comparison of the diagnostic accuracy of the Cognitive Performance Scale (Minimum Data Set) and the Mini-Mental State Exam for the detection of cognitive impairment in nursing home residents
    Louis Paquay
    Department of General Practice, KULeuven, Belgium
    Int J Geriatr Psychiatry 22:286-93. 2007
    ..The Cambridge Examination for Mental Disorders of the Elderly--Revised (CAMDEX-R) was used as the reference standard...
  27. doi request reprint The process of definitive institutionalization of community dwelling demented vs non demented elderly: data obtained from a network of sentinel general practitioners
    Birgitte Schoenmakers
    Catholic University Leuven, Academic Centre of General Practice, Leuven, Belgium
    Int J Geriatr Psychiatry 24:523-31. 2009
    ..The aim of the present study was to investigate the differences between characteristics of community dwelling demented and non demented elderly and their caregivers at the moment of definitive institutionalization...
  28. doi request reprint The relation between care giving and the mental health of caregivers of demented relatives: a cross-sectional study
    Birgitte Schoenmakers
    Academic Centre of General Practice, Department of Public Health, Catholic University Leuven, Leuven, Belgium
    Eur J Gen Pract 15:99-106. 2009
    ..Since the most common cause of failure of a home-care situation appears to be caregiver burnout, detecting critical, negative changes in the wellbeing of the caregiver is important...
  29. doi request reprint Diagnostic value of clinical features at presentation to identify serious infection in children in developed countries: a systematic review
    Ann Van den Bruel
    Department of General Practice, Katholieke Universiteit Leuven, Leuven, Belgium
    Lancet 375:834-45. 2010
    ..Our aim was to identify which clinical features have value in confirming or excluding the possibility of serious infection in children presenting to ambulatory care settings in developed countries...
  30. pmc Excess of mortality in patients with chest pain peaks in the first 3 days period after the incident and normalizes after 1 month
    Rudi Bruyninckx
    Department of General Practice, Katholieke Universiteit Leuven, Leuven, Belgium
    Fam Pract 27:604-8. 2010
    ..These patients are at risk of mortality and should be recognized and referred to secondary care. Aim. To determine the relationship between referral type and mortality in patients with chest pain...
  31. ncbi request reprint Chest pain in general practice or in the hospital emergency department: is it the same?
    F Buntinx
    Department of General Practice, Katholieke Universiteit Leuven, Belgium
    Fam Pract 18:586-9. 2001
    ..The aim of the present study was to provide a description of the impact of setting on the diagnostic case mix that is identified in consecutive patients presenting with chest pain...
  32. ncbi request reprint Epidemiology and comorbidity of erysipelas in primary care
    Stefaan Bartholomeeusen
    Department of General Practice, Katholieke Universiteit Leuven, Belgium
    Dermatology 215:118-22. 2007
    ..Most studies on the epidemiology of erysipelas are done in hospitals, resulting in patient selection. The aim of this study is to determine epidemiological characteristics and comorbidity of erysipelas based on primary care data...
  33. doi request reprint Rate of accidental falls in institutionalised older people with and without cognitive impairment halved as a result of a staff-oriented intervention
    Anne Bouwen
    Department of Katholieke Universiteit, Leuven, Belgium
    Age Ageing 37:306-10. 2008
    ..to evaluate the impact of a staff-oriented intervention on the number of accidental falls in residents with and without cognitive impairment...
  34. pmc Trends in total cholesterol screening and in prescribing lipid-lowering drugs in general practice in the period 1994-2003
    Stefaan Bartholomeeusen
    Department of General Practice, Katholieke Universiteit Leuven, Kapucijnenvoer 33, Leuven, Belgium
    BMC Fam Pract 9:39. 2008
    ..Guidelines for treatment have been adopted. We investigated the consequences on the practice of GPs screening cholesterol levels and on the timing of starting statin prescription...
  35. ncbi request reprint Infections in residents of nursing homes
    Catharina Matheï
    Department of General Practice, KU Leuven, Kapucijnenvoer 33 Blok J, 3000 Leuven, Belgium
    Infect Dis Clin North Am 21:761-72, ix. 2007
    ..Infection control measures should be based upon the particularities of the specific setting of a nursing home and its residents...
  36. ncbi request reprint Selenium is inversely associated with bladder cancer risk: a report from the Belgian case-control study on bladder cancer
    Eliane Kellen
    Department of General Practice, Katholieke Universiteit Leuven, Comprehensive Cancer Institute Limburg, Belgium
    Int J Urol 13:1180-4. 2006
    ..Selenium is an essential trace element with suspected anticarcinogenic properties in humans. To date, eight epidemiological studies have examined the association between serum selenium concentration and bladder cancer risk...
  37. ncbi request reprint The epidemiology of hepatitis C among injecting drug users in Belgium
    C Mathei
    Department of General Practice, Katholieke Universiteit Leuven, Leuven, Belgium
    Acta Gastroenterol Belg 68:50-4. 2005
    ....
  38. pmc A cohort study on the evolution of psychosocial problems in older patients with breast or colorectal cancer: comparison with younger cancer patients and older primary care patients without cancer
    Laura Deckx
    Department of General Practice, KU Leuven, Kapucijnenvoer 33, Bus 7001, 3000, Leuven, Belgium
    BMC Geriatr 15:79. 2015
    ..The evolution of depression, cognitive functioning, and fatigue was evaluated in a group of older cancer patients in comparison with a group of younger cancer patients and older persons without cancer...
  39. pmc Geriatric screening tools are of limited value to predict decline in functional status and quality of life: results of a cohort study
    Laura Deckx
    Department of General Practice, KU Leuven, Kapucijnenvoer 33, Bus 7001, 3000, Leuven, Belgium
    BMC Fam Pract 16:30. 2015
    ....
  40. pmc Time trends in the incidence of peptic ulcers and oesophagitis between 1994 and 2003
    Stefaan Bartholomeeusen
    Department of General Practice, Katholieke Universiteit Leuven, Belgium
    Br J Gen Pract 57:497-9. 2007
    ..In 10 years the proportion of patients taking proton-pump inhibitors rose sixfold while the proportion taking H(2) antagonists remained stable...
  41. ncbi request reprint Insufficient lighting in nursing homes
    Jan De Lepeleire
    Katholieke Universiteit Leuven, Department General Practice, Leuven, Belgium
    J Am Med Dir Assoc 8:314-7. 2007
    ..The objective of this study was to measure the level of lighting in nursing homes in a variety of areas to determine its adequacy in meeting the visual needs of elderly residents...
  42. doi request reprint Factors determining the impact of care-giving on caregivers of elderly patients with dementia. A systematic literature review
    Birgitte Schoenmakers
    Academic Centre of General Practice, Catholic University Leuven, Leuven, Belgium
    Maturitas 66:191-200. 2010
    ..Others, depression in caregivers remains the main cause of a premature or acute ending of home care...
  43. doi request reprint Can pharmacological treatment of behavioural disturbances in elderly patients with dementia lower the burden of their family caregiver?
    Birgitte Schoenmakers
    Department of Public Health, Academic Centre of General Practice, Catholic University of Leuven, Kapucijnenvoer 33, Blok J, Box 7001, Leuven 3000, Belgium
    Fam Pract 26:279-86. 2009
    ....
  44. pmc GPs' reasons for referral of patients with chest pain: a qualitative study
    Rudi Bruyninckx
    Department of General Practice, Katholieke Universiteit Leuven, Leuven, Belgium
    BMC Fam Pract 10:55. 2009
    ..The aim of our study was to identify GPs' reasons for referring or not referring patients presenting with chest pain...
  45. ncbi request reprint Examining the co-occurrence of bladder and prostate cancer: a worthwhile investigation?
    Eliane Kellen
    Universitaire Ziekenhuizen Leuven LUCK, Kapucijnenvoer 33, B 3000 Leuven, Belgium
    Future Oncol 3:515-9. 2007
    ..The prognosis after a diagnosis of both bladder and prostate cancer seems to depend mainly on the prognosis of the bladder tumor...
  46. ncbi request reprint Molecular epidemiology of hepatitis C among drug users in Flanders, Belgium: association of genotype with clinical parameters and with sex- and drug-related risk behaviours
    C Mathei
    Department of General Practice, Katholieke Universiteit Leuven, Kapucijnenvoer 33 Blok J, 3000, Leuven, Belgium
    Eur J Clin Microbiol Infect Dis 24:514-22. 2005
    ..Finally, the results suggest that tattooing practices play a role in the spread of HCV among drug users...
  47. pmc Prevalence of hepatitis C in drug users in Flanders: determinants and geographic differences
    C Mathei
    Department of General Practice, Katholieke Universiteit Leuven, Leuven, Belgium
    Epidemiol Infect 133:127-36. 2005
    ..This was explained not only by variations in drug-related risk behaviour, but also by differences in sexual risk behaviour and socio-economic status...
  48. ncbi request reprint Evidence for a substantial role of sharing of injecting paraphernalia other than syringes/needles to the spread of hepatitis C among injecting drug users
    C Mathei
    Department of General Practice, Katholieke Universiteit Leuven, Leuven, Belgium
    J Viral Hepat 13:560-70. 2006
    ..It was found that sharing of materials other than syringes/needles indeed seemed to contribute substantially to the spread of hepatitis C among injecting drug users...
  49. pmc Incidence and outcome of first syncope in primary care: A retrospective cohort study
    Peter Vanbrabant
    Emergency Department, University Hospitals Leuven, Herestraat 49, B 3000 Leuven, Belgium
    BMC Fam Pract 12:102. 2011
    ..Compared to a control group, syncope on itself is an independent risk factor for serious outcome (adjusted for age, gender, CV comorbidity and risk factors)...
  50. pmc Influence of metformin intake on the risk of bladder cancer in type 2 diabetes patients
    Maria E Goossens
    Department of General Practice, KU Leuven, Leuven, Belgium
    Br J Clin Pharmacol 80:1464-72. 2015
    ..The aim of this study was to look at the influence of metformin intake and duration, on urinary bladder cancer (UBC) risk, with sulfonylurea (SU) only users as control using a new user design (inception cohort)...
  51. pmc The correlation between blood pressure and kidney function decline in older people: a registry-based cohort study
    Bert Vaes
    Department of General Practice, Universiteit Leuven KU Leuven, Leuven, Belgium Institute of Health and Society, Universite Catholique de Louvain UCL, Brussels, Belgium
    BMJ Open 5:e007571. 2015
    ..To examine the relation between static and dynamic blood pressure (BP) measurements and the evolution of kidney function in older people, adjusted for the presence of multimorbidity...
  52. pmc Association between atrial fibrillation, anticoagulation, risk of cerebrovascular events and multimorbidity in general practice: a registry-based study
    Vigdis Vanbeselaere
    Department of General Practice, KU Leuven KUL, Kapucijnenvoer 33, blok j bus 7001, 3000, Leuven, Belgium
    BMC Cardiovasc Disord 16:61. 2016
    ..In addition, the correlation between multimorbidity and the use of anticoagulants and the risk of cerebrovascular events considering multimorbidity was explored in AF patients...
  53. pmc Signs and symptoms in children with a serious infection: a qualitative study
    Ann Van den Bruel
    Department of General Practice, Katholieke Universiteit Leuven, Belgium
    BMC Fam Pract 6:36. 2005
    ..Little is known which signs and symptoms are important in general practice. With this qualitative study, we aimed to identify possible new important diagnostic variables...
  54. ncbi request reprint Pooled analysis and meta-analysis of the glutathione S-transferase P1 Ile 105Val polymorphism and bladder cancer: a HuGE-GSEC review
    Eliane Kellen
    Department of General Practice, Katholieke Universiteit Leuven, Comprehensive Cancer Institute Limburg, Limburg, Belgium
    Am J Epidemiol 165:1221-30. 2007
    ..Case-only analyses did not detect an interaction between the GSTP1 genotype and smoking status (never/ever). GSTP1 Ile 105Val appears to be associated with a modest increase in the risk of bladder cancer...
  55. pmc Dealing with low-incidence serious diseases in general practice
    Frank Buntinx
    Department of General Practice, Catholic University of Leuven, Belgium
    Br J Gen Pract 61:43-6. 2011
    ..However, this construction of an evidence base requires very large-scale studies, and the global primary care research community remains small. The challenge therefore needs to be met by urgent and effective international collaboration...
  56. ncbi request reprint The denominator in general practice, a new approach from the Intego database
    Stefaan Bartholomeeusen
    Department of General Practice, Katholieke Universiteit Leuven, B 3000 Leuven, Belgium
    Fam Pract 22:442-7. 2005
    ..To determine the denominator or the 'population at risk' is a problem which has long been encountered in general practice-based epidemiological research. It is important for calculating epidemiological figures...
  57. pmc Diagnosing dementia: no easy job
    Frank Buntinx
    Katholieke Universiteit Leuven, Department of General Practice, Kapucijnenvoer 33, Blok J, B 3000 Leuven, Belgium
    BMC Fam Pract 12:60. 2011
    ..From both clinical experience and research we learned that in complex progressive disorders such as dementia, diagnosis includes multiple steps, each with their own clinical and research characteristics...
  58. ncbi request reprint Use of selenium in chemoprevention of bladder cancer
    Maree Brinkman
    Department of General Practice, Katholieke University of Leuven, Leuven, Belgium
    Lancet Oncol 7:766-74. 2006
    ..Future studies should assess the best dose and form of selenium, and whether the protective effect of selenium differs between the sexes...
  59. doi request reprint The use of human tissue in epidemiological research; ethical and legal considerations in two biobanks in Belgium
    Carla Truyers
    Department of General Practice, Katholieke Universiteit Leuven, Kapucijnenvoer 33, Blok J, Bus 7001, 3000, Leuven, Belgium
    Med Health Care Philos 13:169-75. 2010
    ..We will address the principle of consent (broad versus specific) and the type of data recorded (anonymous, encoded and identifiable) for both biobanks...
  60. ncbi request reprint Cardiovascular risk in white-coat and sustained hypertensive patients
    Hilde Celis
    Study Coordinating Centre, Hypertension and Cardiovascular Rehabilitation Unit, Department of Molecular and Cardiovascular Research, University of Leuven, Leuven, Belgium
    Blood Press 11:352-6. 2002
    ..Although white-coat hypertension was less frequently associated with antihypertensive drug treatment during follow-up, it carried a significantly better prognosis than sustained hypertension...
  61. doi request reprint Identifying an accurate pre-screening tool in geriatric oncology
    Eliane Kellen
    Leuven Centre of Cancer Prevention, University Hospitals Leuven, Belgium
    Crit Rev Oncol Hematol 75:243-8. 2010
    ..14% had two or more impairments of the CGA or were cognitively impaired. The physical and disability questions are useful, but all other screening instruments miss too many cases...
  62. ncbi request reprint The relation between alcohol abuse or dependence and academic performance in first-year college students
    Bert Aertgeerts
    Department of General Practice, Clinical Epidemiology Unit, Katholieke Universiteit, Leuven, Belgium
    J Adolesc Health 31:223-5. 2002
    ..6%) were alcohol-dependent. Of the students who met criteria of alcohol dependence, 62.5% failed in their first year, compared to 50% among students who did not report these drinking problems...
  63. ncbi request reprint A combination of tests for the diagnosis of dementia had a significant diagnostic value
    J De Lepeleire
    Department of General Practice, ACHG, Katholieke Universiteit Leuven, Kapucijnenvoer 33, Blok J, 3000 Leuven, Belgium
    J Clin Epidemiol 58:217-25. 2005
    ..To study the diagnostic parameters of a number of instruments for a diagnosis of dementia in general practice and the added diagnostic value of these tests...
  64. ncbi request reprint The value of the CAGE in screening for alcohol abuse and alcohol dependence in general clinical populations: a diagnostic meta-analysis
    B Aertgeerts
    Department of General Practice, Clinical Epidemiology Unit, Katholicke Universiteit Leuven, Kapucijnenvoer 33, Blok J, B 3000 Leuven, Belgium
    J Clin Epidemiol 57:30-9. 2004
    ..To perform a meta-analysis to assess diagnostic characteristics of the CAGE in screening for alcohol abuse or dependence in a general clinical population and to test a new method for pooling of ROC curves...
  65. ncbi request reprint Seroprevalence of hepatitis C markers among intravenous drug users in western European countries: a systematic review
    Catharina Matheï
    Department of General Practice, Katholieke Universiteit Leuven, Belgium
    J Viral Hepat 9:157-73. 2002
    ..We found no conclusive explanation for this variability. Further research investigating the dynamics of the hepatitis C epidemic in IVDUs is necessary...
  66. ncbi request reprint CUGE: a screening instrument for alcohol abuse and dependence in students
    A Van Den Bruel
    Department of General Practice, Katholieke Universiteit Leuven, Belgium
    Alcohol Alcohol 39:439-44. 2004
    ..In order to determine the diagnostic value of this new questionnaire, we set up a validation study in a new and independent population of freshmen...
  67. ncbi request reprint Interval cancers in the beginning years of the breast cancer screening programme in the Belgian province of Limburg
    E Kellen
    Leuven University Centre for Cancer Prevention LUCK, Leuven, Belgium
    Acta Clin Belg 63:179-84. 2008
    ..Interval cancers are tumours that are being diagnosed before the next scheduled screening round and are related to the sensitivity and the screening interval...
  68. ncbi request reprint Measuring the body temperature: how accurate is the Tempa Dot?
    A Van Den Bruel
    Katholieke Universiteit Leuven, Kapucijnenvoer 33 Blok J, 3000 Leuven, Belgium
    Technol Health Care 13:97-106. 2005
    ..We evaluated the accuracy of a disposable, sterile thermometer that is practical in use and holds no risk of cross-infections...
  69. ncbi request reprint [The investigation of gene-environment interaction using case-control comparisons]
    E Kellen
    Katholieke Universiteit, Academisch Centrum voor Huisartsgenees kunde, Kapucijnenvoer 33, Blok J, B 3000 Leuven, Belgie
    Ned Tijdschr Geneeskd 149:977-82. 2005
    ..Both the case-parents and the case-only designs assume independence between genotype and environmental factors in the control group...
  70. ncbi request reprint Questionnaires are better than laboratory tests to screen for current alcohol abuse or dependence in a male inpatient population
    B Aertgeerts
    Department of General Practice, Clinical Epidemiology Unit, Katholieke Universiteit Leuven
    Acta Clin Belg 57:241-9. 2002
    ..To assess the diagnostic performance of the CAGE and AUDIT (Alcohol Use Disorder Identification Test) and its derivatives, and laboratory tests for screening alcohol abuse or dependence in a male medical hospital population...
  71. ncbi request reprint Antihypertensive treatment based on conventional or ambulatory blood pressure measurement. A randomized controlled trial. Ambulatory Blood Pressure Monitoring and Treatment of Hypertension Investigators
    J A Staessen
    Hypertensie en Cardiovasculaire Revalidatie Eenheid, Departement voor Moleculair en Cardiovasculaire Onderzoek, Katholieke Universiteit Leuven, Belgium
    JAMA 278:1065-72. 1997
    ..Ambulatory blood pressure (ABP) monitoring is used increasingly in clinical practice, but how it affects treatment of blood pressure has not been determined...
  72. ncbi request reprint Disclosing the diagnosis of dementia: the performance of Flemish general practitioners
    J De Lepeleire
    Katholieke Universiteit Leuven, Belgium
    Int Psychogeriatr 16:421-8. 2004
    ..Recent data confirm that the patient is told of the diagnosis in only 40 to 55% of cases. We therefore studied the performance of Flemish general practitioners (GPs) in this area...
  73. ncbi request reprint [Evidence-based medicine: a discussion of the most frequently occurring criticisms]
    K Hannes
    Belgisch Centrum voor Evidence Based Medicine Belgische tak van het Nederlandse Cochrane Centre, Kapucijnenvoer 33, Blok J, 3000 Leuven, Belgie
    Ned Tijdschr Geneeskd 149:1983-8. 2005
    ..EBM is just one of the weapons in the armoury of the caregiver in the battle for the optimal provision...
  74. ncbi request reprint [Prevalence of alcohol abuse and alcohol dependence according to DSM-IV criteria in first year university students]
    B Aertgeerts
    afd Huisartsgeneeskunde, Katholieke Universiteit, Kapucijnenvoer 33, Leuven
    Ned Tijdschr Geneeskd 143:2621-4. 1999
    ..To determine the prevalence of alcohol problems in first-year college students...
  75. ncbi request reprint The value of CAGE, CUGE, and AUDIT in screening for alcohol abuse and dependence among college freshmen
    B Aertgeerts
    Department of General Practice, University Hospital Gasthuisberg, Catholic University of Leuven, Belgium
    Alcohol Clin Exp Res 24:53-7. 2000
    ....
  76. ncbi request reprint Is there a difference between CAGE interviews and written CAGE questionnaires?
    B Aertgeerts
    Department of General Practice, Katholieke Universiteit Leuven, Belgium
    Alcohol Clin Exp Res 24:733-6. 2000
    ....
  77. ncbi request reprint [Systemic validation of clinical practice guidelines: the AGREE network]
    K Hannes
    Centre Belge d Evidence Based Medicine CEBAM
    Rev Med Liege 60:949-56. 2005
    ..There is a growing need for the developement of a set of criteria to ensure that potential biases inherent in guideline development have been properly addressed and that the recommendations for practice are valid and reliable...
  78. pmc Screening properties of questionnaires and laboratory tests for the detection of alcohol abuse or dependence in a general practice population
    B Aertgeerts
    Department of General Practice, Clinical Epidemiology Unit, University Hospital Gasthuisberg, Catholic University of Leuven, Belgium
    Br J Gen Pract 51:206-17. 2001
    ..Early identification of alcohol abuse or dependence is important in general practice because many diseases are influenced by alcohol. General practitioners, however, fail to recognise most patients with alcohol problems...
  79. doi request reprint Care trajectories are associated with quality improvement in the treatment of patients with uncontrolled type 2 diabetes: A registry based cohort study
    Geert Goderis
    Department of General Practice, Katholieke Universiteit Leuven, Leuven, Belgium Electronic address
    Prim Care Diabetes 9:354-61. 2015
    ..Introduced in 2009 in Belgium, CTs target patients with type 2 diabetes mellitus (T2DM), in need for or with PHT...
  80. doi request reprint How do general practitioners use 'safety netting' in acutely ill children?
    Karen Bertheloot
    a Department of General Practice, KU Leuven, Leuven, Belgium
    Eur J Gen Pract 22:3-8. 2016
    ..It informs patients on 'red flag' features and when and how to seek further help. There is, however, insufficient evidence to support useful choices regarding 'safety netting' procedures...
  81. ncbi request reprint Can the heartscan be used for diagnosis and monitoring of emergencies in general practice?
    Walter Renier
    Dept of General Practice, Katholieke Universiteit Leuven, Leuven, Belgium
    Acta Cardiol 67:525-31. 2012
    ..We presumed the heartscan, a handheld wireless device, to be of value to a GP in emergency situations. We therefore studied inter- and intra-observer variability and the accuracy of the screen readings...
  82. pmc Signs and symptoms in diagnosing acute myocardial infarction and acute coronary syndrome: a diagnostic meta-analysis
    Rudi Bruyninckx
    Department of General Practice, Katholieke Universiteit Leuven, Belgium
    Br J Gen Pract 58:105-11. 2008
    ..Prompt diagnosis of acute myocardial infarction or acute coronary syndrome is very important...
  83. ncbi request reprint The Belgian Improvement Study on Oral Anticoagulation Therapy: a randomized clinical trial
    Neree Claes
    Department of General Practice, Catholic University Leuven, Kapucijnenvoer, 33 Blok J, B 3000 Leuven, Leuven, Belgium
    Eur Heart J 26:2159-65. 2005
    ..To improve the quality of oral anticoagulation management by GPs and to compare different models and interventions, a randomized clinical trial was performed...
  84. doi request reprint Consumption of animal products, olive oil and dietary fat and results from the Belgian case-control study on bladder cancer risk
    Maree T Brinkman
    Department of General Practice, Katholieke Universiteit Leuven, Comprehensive Cancer Institute Limburg, LIKAS, Leuven, Belgium
    Eur J Cancer 47:436-42. 2011
    ..Therefore, we investigated the effect of intake of animal products, olive oil and other major dietary fats on bladder cancer risk...
  85. ncbi request reprint Results of diagnostic accuracy studies are not always validated
    Ann Van den Bruel
    Department of General Practice ACHG, Katholieke Universiteit Leuven, Kapucijnenvoer 33, Blok J, 3000 Leuven, Belgium
    J Clin Epidemiol 59:559-66. 2006
    ..Here we describe whether diagnostic research is validated, which technique is used, and to what extent the validation study results differ from the original...
  86. doi request reprint A quasi-randomized trial on the effectiveness of an invitation letter to improve participation in a setting of opportunistic screening for cervical cancer
    Eric De Jonge
    Limburgs Cancer Registar, Limburgse Kanker Stichting, Stadsomvaart 9, B 3500 Hassett, Belgium
    Eur J Cancer Prev 17:238-42. 2008
    ....
  87. doi request reprint The epidemic history of hepatitis C among injecting drug users in Flanders, Belgium
    C Mathei
    Department of General Practice, Katholieke Universiteit Leuven, Leuven, Belgium
    J Viral Hepat 15:399-408. 2008
    ..Moreover, results suggested that the hepatitis C subtype 3a epidemic has reached a steady state, while the hepatitis C 1a epidemic has not, which therefore might become the predominant subtype among IDUs...
  88. ncbi request reprint The frequency and outcome of acute dyspnoea in primary care: An observational study
    Karin von Winckelmann
    a Department of General Practice, Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium
    Eur J Gen Pract . 2016
    ..Little is known about the occurrence of acute dyspnoea in primary care and its underlying causes...
  89. pmc Risk of bladder cancer in patients with diabetes: a retrospective cohort study
    Maria E Goossens
    Department of General Practice, KU Leuven, Leuven, Belgium
    BMJ Open 5:e007470. 2015
    ..The objective of this study was to examine the association between diabetes, and both urinary bladder cancer (UBC) risk and mortality...
  90. doi request reprint Risk factors for loneliness in patients with cancer: a systematic literature review and meta-analysis
    Laura Deckx
    Department of General Practice, KU Leuven, Kapucijnenvoer 33, Bus 7001, 3000 Leuven, Belgium Electronic address
    Eur J Oncol Nurs 18:466-77. 2014
    ..To systematically review the literature on the severity and risk factors for loneliness in adult cancer patients...
  91. pmc Diagnosing serious infections in acutely ill children in ambulatory care (ERNIE 2 study protocol, part A): diagnostic accuracy of a clinical decision tree and added value of a point-of-care C-reactive protein test and oxygen saturation
    Jan Y Verbakel
    Department of General Practice, KU Leuven, Kapucijnenvoer 33, 3000 Leuven, Belgium
    BMC Pediatr 14:207. 2014
    ..To reduce the number of false positives, point-of-care tests might be useful, providing an immediate result at bedside. The most probable candidate is C-reactive protein, as well as a pulse oximetry...
  92. pmc Chronic Diseases among Older Cancer Survivors
    Laura Deckx
    Department of General Practice, Katholieke Universiteit Leuven, Kapucijnenvoer 33, Bus 7001, 3000 Leuven, Belgium
    J Cancer Epidemiol 2012:206414. 2012
    ..However, apart from COPD and venous thrombosis, the incidence of chronic diseases in older cancer patients is similar compared to non-cancer patients of the same age, sex, and practice...
  93. pmc Study protocol of KLIMOP: a cohort study on the wellbeing of older cancer patients in Belgium and the Netherlands
    Laura Deckx
    Department of General Practice, Katholieke Universiteit Leuven, Kapucijnenvoer 33, Bus 7001, 3000 Leuven, Belgium
    BMC Public Health 11:825. 2011
    ..Therefore, this study will focus on the impact of cancer, ageing, and their interaction on the long-term wellbeing of older cancer patients...
  94. pmc Supporting family carers of community-dwelling elder with cognitive decline: a randomized controlled trial
    Birgitte Schoenmakers
    Academic Centre of General Practice, Catholic University Leuven, Kapucijnenvoer 33, Blok J, Box 7001, 3000 Leuven, Belgium
    Int J Family Med 2010:184152. 2010
    ..Conclusion. Carers do not always need to be surrounded with more professionals, but they want to feel more supported. In terms of policy, this could have some important implications...
  95. ncbi request reprint Frequency of the CCR5-Delta32 mutant allele is not increased in Belgian hepatitis C virus-infected patients
    Inge Thoelen
    Laboratory of Clinical and Epidemiological Virology, Department of Microbiology and Immunology, Rega Institute for Medical Research, University of Leuven, Minderbroedersstraat 10, B 3000 Leuven, Belgium
    Viral Immunol 18:232-5. 2005
    ..Moreover, genotype distributions in both populations were in agreement with Hardy-Weinberg equilibrium. Our results do not support the hypothesis that the CCR5-Delta32 mutant allele is a risk factor for hepatitis C virus infection...
  96. ncbi request reprint Fruit consumption reduces the effect of smoking on bladder cancer risk. The Belgian case control study on bladder cancer
    Eliane Kellen
    Department of General Practice, Comprehensive Cancer Institute Limburg, Katholieke Universiteit Leuven, Belgium
    Int J Cancer 118:2572-8. 2006
    ..Antioxidants, found in fruit, may protect against the damage caused by free radicals found in cigarette smoke. Metabolic polymorphisms appear not to modify this relation...
  97. ncbi request reprint Molecular epidemiology of methicillin-resistant Staphylococcus aureus in nursing homes: a cross-sectional study
    Annette Hoefnagels-Schuermans
    Infection Control and Hospital Epidemiology, The University Hospitals, Leuven, Belgium
    Infect Control Hosp Epidemiol 23:546-9. 2002
    ..9%. The three clones identified by genetic analysis were identical to those in the acute care facilities; only their relative prevalence differed. Clone 2 took epidemic proportions in five of these nursing homes...
  98. ncbi request reprint Diagnosing depression: what's in a name?
    Frank Buntinx
    Department of Gneral Practice, University of Leuven, B 3000 Leuven, Belgium
    Eur J Gen Pract 10:162-5, 168. 2004
    ..We tried to identify possible explanations for these differences...
  99. ncbi request reprint Prostate-specific antigen screening coverage and prostate cancer incidence rates in the Belgian province of Limburg in 1996-1998
    D Lousbergh
    Department of General Practice Clinical Epidemiology Unit, University of Leuven, Belgium
    Eur J Cancer Prev 11:547-9. 2002
    ..This could result from no such relationship existing or from low statistical power...
  100. doi request reprint Social and behavioural risk factors for HIV infection among the wives of labour migrants in Nepal
    Subash Thapa
    Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium
    Int J STD AIDS 25:793-9. 2014
    ....
  101. pmc The Intego database: background, methods and basic results of a Flemish general practice-based continuous morbidity registration project
    Carla Truyers
    Department of General Practice, Kapucijnenvoer 33 blok j bus 7001 te B 3000 Leuven, Katholieke Universiteit Leuven, Leuven, Belgium
    BMC Med Inform Decis Mak 14:48. 2014
    ..Intego collects data from over 90 general practitioners. All the information is routinely collected in the electronic health record during daily practice...