Youssef Gali

Summary

Affiliation: Institute of Tropical Medicine
Country: Belgium

Publications

  1. pmc Transcriptome analysis of monocyte-HIV interactions
    Rafael Van den Bergh
    Department of Molecular and Cellular Interactions, VIB, Brussels, Belgium
    Retrovirology 7:53. 2010
  2. pmc Analysis of infectious virus clones from two HIV-1 superinfection cases suggests that the primary strains have lower fitness
    Antoinette C van der Kuyl
    Laboratory of Experimental Virology, Department of Medical Microbiology, Centre for Infection and Immunity Amsterdam CINIMA, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Retrovirology 7:60. 2010
  3. ncbi Survey of the temporal changes in HIV-1 replicative fitness in the Amsterdam Cohort
    Youssef Gali
    Department of Microbiology, Virology Unit, Institute of Tropical Medicine, Nationalestraat 155, B 2000 Antwerp, Belgium
    Virology 364:140-6. 2007
  4. doi Development of an in vitro dual-chamber model of the female genital tract as a screening tool for epithelial toxicity
    Youssef Gali
    Virology Unit, Department of Microbiology, Institute of Tropical Medicine, B 2000 Antwerpen, Belgium
    J Virol Methods 165:186-97. 2010
  5. pmc In vitro evaluation of viability, integrity, and inflammation in genital epithelia upon exposure to pharmaceutical excipients and candidate microbicides
    Youssef Gali
    Department of Microbiology, Virology Unit, Institute of Tropical Medicine, Nationalestraat 155, B 2000 Antwerp, Belgium
    Antimicrob Agents Chemother 54:5105-14. 2010
  6. pmc The predominance of Human Immunodeficiency Virus type 1 (HIV-1) circulating recombinant form 02 (CRF02_AG) in West Central Africa may be related to its replicative fitness
    Harr F Njai
    HIV and Retrovirology Research Unit, Department of Microbiology, Institute of Tropical Medicine, 155 Nationalestraat, B 2000 Antwerp, Belgium
    Retrovirology 3:40. 2006
  7. ncbi Replicative fitness of historical and recent HIV-1 isolates suggests HIV-1 attenuation over time
    Kevin K Ariën
    Department of Microbiology, HIV and Retrovirology Research Unit, Institute of Tropical Medicine, Antwerp, Belgium
    AIDS 19:1555-64. 2005
  8. doi A dual-chamber model of the female genital tract to evaluate epithelial toxicity of candidate anti-HIV microbicides
    Kevin K Ariën
    Virology Unit, Department of Microbiology, Institute of Tropical Medicine, Antwerp, Belgium
    Curr Protoc Cell Biol . 2011
  9. ncbi Replicative fitness of CCR5-using and CXCR4-using human immunodeficiency virus type 1 biological clones
    Kevin K Ariën
    HIV and Retrovirology Research Unit, Department of Microbiology, Institute for Tropical Medicine, Nationalestraat 155, B 2000 Antwerpen, Belgium
    Virology 347:65-74. 2006

Collaborators

Detail Information

Publications9

  1. pmc Transcriptome analysis of monocyte-HIV interactions
    Rafael Van den Bergh
    Department of Molecular and Cellular Interactions, VIB, Brussels, Belgium
    Retrovirology 7:53. 2010
    ..We therefore applied a parallel approach of genome-wide microarray analysis and focused gene expression profiling on monocytes from patients in different stages of HIV infection and/or ART to further characterise these dysfunctions...
  2. pmc Analysis of infectious virus clones from two HIV-1 superinfection cases suggests that the primary strains have lower fitness
    Antoinette C van der Kuyl
    Laboratory of Experimental Virology, Department of Medical Microbiology, Centre for Infection and Immunity Amsterdam CINIMA, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Retrovirology 7:60. 2010
    ..The use of isolate-specific primer sets indicated that the primary and secondary strains co-exist in plasma at all time points after the moment of superinfection...
  3. ncbi Survey of the temporal changes in HIV-1 replicative fitness in the Amsterdam Cohort
    Youssef Gali
    Department of Microbiology, Virology Unit, Institute of Tropical Medicine, Nationalestraat 155, B 2000 Antwerp, Belgium
    Virology 364:140-6. 2007
    ..Apparently, the bottleneck, occurring with each transmission event, does not completely reset the fitness increase acquired during disease progression...
  4. doi Development of an in vitro dual-chamber model of the female genital tract as a screening tool for epithelial toxicity
    Youssef Gali
    Virology Unit, Department of Microbiology, Institute of Tropical Medicine, B 2000 Antwerpen, Belgium
    J Virol Methods 165:186-97. 2010
    ..In conclusion, this model is a useful tool to (1) study HIV-1 transmission mechanisms and (2) evaluate epithelial toxicity of candidate microbicides...
  5. pmc In vitro evaluation of viability, integrity, and inflammation in genital epithelia upon exposure to pharmaceutical excipients and candidate microbicides
    Youssef Gali
    Department of Microbiology, Virology Unit, Institute of Tropical Medicine, Nationalestraat 155, B 2000 Antwerp, Belgium
    Antimicrob Agents Chemother 54:5105-14. 2010
    ..In conclusion, identification of safety issues concerning the use of pharmaceutical excipients could help to formulate less toxic vaginal microbicide preparations...
  6. pmc The predominance of Human Immunodeficiency Virus type 1 (HIV-1) circulating recombinant form 02 (CRF02_AG) in West Central Africa may be related to its replicative fitness
    Harr F Njai
    HIV and Retrovirology Research Unit, Department of Microbiology, Institute of Tropical Medicine, 155 Nationalestraat, B 2000 Antwerp, Belgium
    Retrovirology 3:40. 2006
    ..Growth competition experiments were carried out at equal multiplicity of infection in activated T cells and monocyte-derived dendritic cells (MO-DC) in parallel...
  7. ncbi Replicative fitness of historical and recent HIV-1 isolates suggests HIV-1 attenuation over time
    Kevin K Ariën
    Department of Microbiology, HIV and Retrovirology Research Unit, Institute of Tropical Medicine, Antwerp, Belgium
    AIDS 19:1555-64. 2005
    ..Here we used primary human cells to study the replicative fitness of primary HIV-1 isolates from untreated patients, comparing historical (1986-1989) and recent samples (2002-2003)...
  8. doi A dual-chamber model of the female genital tract to evaluate epithelial toxicity of candidate anti-HIV microbicides
    Kevin K Ariën
    Virology Unit, Department of Microbiology, Institute of Tropical Medicine, Antwerp, Belgium
    Curr Protoc Cell Biol . 2011
    ..Here we describe how this in vitro model can be used to assess the cellular toxicity and anti-HIV activity of antiretrovirals and formulations thereof that are intended to be used as microbicides...
  9. ncbi Replicative fitness of CCR5-using and CXCR4-using human immunodeficiency virus type 1 biological clones
    Kevin K Ariën
    HIV and Retrovirology Research Unit, Department of Microbiology, Institute for Tropical Medicine, Nationalestraat 155, B 2000 Antwerpen, Belgium
    Virology 347:65-74. 2006
    ..These observations suggest that interaction between X4 viruses, DC and T cells might contribute to the preferential outgrowth of X4 viruses in AIDS patients...