Luc Leybaert

Summary

Affiliation: Ghent University
Country: Belgium

Publications

  1. doi request reprint Ca(2+) regulation of connexin 43 hemichannels in C6 glioma and glial cells
    Elke De Vuyst
    Department of Basic Medical Sciences, Ghent University, Belgium
    Cell Calcium 46:176-87. 2009
  2. pmc Intercellular Ca(2+) waves: mechanisms and function
    Luc Leybaert
    Department of Basic Medical Sciences, Physiology Group, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium
    Physiol Rev 92:1359-92. 2012
  3. ncbi request reprint A simple and practical method to acquire geometrically correct images with resonant scanning-based line scanning in a custom-built video-rate laser scanning microscope
    L Leybaert
    Department Physiology and Pathophysiology, Faculty of Medicine and Health Sciences, Ghent University, De Pintelaan 185, B 9000 Ghent, Belgium
    J Microsc 219:133-40. 2005
  4. ncbi request reprint IP3, still on the move but now in the slow lane
    Luc Leybaert
    Physiology Group, Department of Basic Medical Sciences, Faculty of Medicine and Health Sciences, Ghent University, De Pintelaan 185, 9000 Ghent, Belgium
    Sci Signal 9:fs17. 2016
  5. ncbi request reprint Calcium signal communication between glial and vascular brain cells
    Luc Leybaert
    Department of Physiology and Pathophysiology, Ghent University, B 9000 Ghent, Belgium
    Acta Neurol Belg 104:51-6. 2004
  6. ncbi request reprint Neurobarrier coupling in the brain: adjusting glucose entry with demand
    Luc Leybaert
    Department of Physiology and Pathophysiology, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium
    J Neurosci Res 85:3213-20. 2007
  7. ncbi request reprint Connexin channels, connexin mimetic peptides and ATP release
    Luc Leybaert
    Department of Physiology and Pathophysiology, Ghent University, Ghent, Belgium
    Cell Commun Adhes 10:251-7. 2003
  8. ncbi request reprint Neurobarrier coupling in the brain: a partner of neurovascular and neurometabolic coupling?
    Luc Leybaert
    Department of Physiology and Pathophysiology, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium
    J Cereb Blood Flow Metab 25:2-16. 2005
  9. doi request reprint Low extracellular Ca2+ conditions induce an increase in brain endothelial permeability that involves intercellular Ca2+ waves
    Marijke De Bock
    Department of Basic Medical Sciences, Physiology Group, Ghent University, De Pintelaan 185, Building B, 9000 Ghent, Belgium
    Brain Res 1487:78-87. 2012
  10. doi request reprint Endothelial calcium dynamics, connexin channels and blood-brain barrier function
    Marijke De Bock
    Dept of Basic Medical Sciences, Ghent University, Ghent, Belgium
    Prog Neurobiol 108:1-20. 2013

Collaborators

Detail Information

Publications54

  1. doi request reprint Ca(2+) regulation of connexin 43 hemichannels in C6 glioma and glial cells
    Elke De Vuyst
    Department of Basic Medical Sciences, Ghent University, Belgium
    Cell Calcium 46:176-87. 2009
    ....
  2. pmc Intercellular Ca(2+) waves: mechanisms and function
    Luc Leybaert
    Department of Basic Medical Sciences, Physiology Group, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium
    Physiol Rev 92:1359-92. 2012
    ..We review here the mechanisms of initiation and propagation of ICWs, the key intra- and extracellular messengers (inositol 1,4,5-trisphosphate and ATP) mediating ICWs, and the proposed physiological functions of ICWs...
  3. ncbi request reprint A simple and practical method to acquire geometrically correct images with resonant scanning-based line scanning in a custom-built video-rate laser scanning microscope
    L Leybaert
    Department Physiology and Pathophysiology, Faculty of Medicine and Health Sciences, Ghent University, De Pintelaan 185, B 9000 Ghent, Belgium
    J Microsc 219:133-40. 2005
    ..Finally, we demonstrate that the microscope can be used to resolve calcium puffs triggered by photolytically increasing the intracellular concentration of inositol trisphosphate...
  4. ncbi request reprint IP3, still on the move but now in the slow lane
    Luc Leybaert
    Physiology Group, Department of Basic Medical Sciences, Faculty of Medicine and Health Sciences, Ghent University, De Pintelaan 185, 9000 Ghent, Belgium
    Sci Signal 9:fs17. 2016
    ..These findings have implications for the understanding of the mechanisms of Ca2+ wave propagation, especially long-range, cell-to-cell propagating Ca2+ waves...
  5. ncbi request reprint Calcium signal communication between glial and vascular brain cells
    Luc Leybaert
    Department of Physiology and Pathophysiology, Ghent University, B 9000 Ghent, Belgium
    Acta Neurol Belg 104:51-6. 2004
    ....
  6. ncbi request reprint Neurobarrier coupling in the brain: adjusting glucose entry with demand
    Luc Leybaert
    Department of Physiology and Pathophysiology, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium
    J Neurosci Res 85:3213-20. 2007
    ..Further work is needed to demonstrate NBC effects following physiological brain activation in vivo and to identify the signals that lead to NBC in in vitro experiments...
  7. ncbi request reprint Connexin channels, connexin mimetic peptides and ATP release
    Luc Leybaert
    Department of Physiology and Pathophysiology, Ghent University, Ghent, Belgium
    Cell Commun Adhes 10:251-7. 2003
    ..Work performed up to now with these peptides should be re-interpreted in terms of these new findings...
  8. ncbi request reprint Neurobarrier coupling in the brain: a partner of neurovascular and neurometabolic coupling?
    Luc Leybaert
    Department of Physiology and Pathophysiology, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium
    J Cereb Blood Flow Metab 25:2-16. 2005
    ..This review presents neurobarrier coupling within the current knowledge on neurovascular and neurometabolic coupling, and considers arguments and evidence in support of this hypothesis...
  9. doi request reprint Low extracellular Ca2+ conditions induce an increase in brain endothelial permeability that involves intercellular Ca2+ waves
    Marijke De Bock
    Department of Basic Medical Sciences, Physiology Group, Ghent University, De Pintelaan 185, Building B, 9000 Ghent, Belgium
    Brain Res 1487:78-87. 2012
    ..This article is part of a Special Issue entitled Electrical Synapses...
  10. doi request reprint Endothelial calcium dynamics, connexin channels and blood-brain barrier function
    Marijke De Bock
    Dept of Basic Medical Sciences, Ghent University, Ghent, Belgium
    Prog Neurobiol 108:1-20. 2013
    ..The effect of Ca(2+) oscillations/waves on BBB function is largely unknown and we here review current evidence on how [Ca(2+)]i dynamics influence BBB permeability. ..
  11. pmc Connexin 43 hemichannels contribute to cytoplasmic Ca2+ oscillations by providing a bimodal Ca2+-dependent Ca2+ entry pathway
    Marijke De Bock
    Department of Basic Medical Sciences, Physiology Group, Ghent University 9000 Ghent, Belgium
    J Biol Chem 287:12250-66. 2012
    ..Hemichannels were not sufficient to ignite oscillations by themselves; however, their contribution was crucial as hemichannel inhibition stopped the oscillations...
  12. pmc Paracrine signaling through plasma membrane hemichannels
    Nan Wang
    Department of Basic Medical Sciences, Ghent University, Ghent, Belgium
    Biochim Biophys Acta 1828:35-50. 2013
    ..This article is part of a Special Issue entitled: The Communicating junctions, roles and dysfunctions...
  13. pmc Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury
    Nan Wang
    Faculty of Medicine and Health Sciences, Physiology Group, Department of Basic Medical Sciences, Ghent University, Ghent, Belgium
    Basic Res Cardiol 108:309. 2013
    ..We conclude that preventing Cx43 hemichannel opening with Gap19 confers limited protective effects against myocardial ischemia/reperfusion injury...
  14. doi request reprint Calcium and connexin-based intercellular communication, a deadly catch?
    Elke Decrock
    Department of Basic Medical Sciences Physiology group, Faculty of Medicine and Health Sciences, Ghent University, B 9000 Ghent, Belgium
    Cell Calcium 50:310-21. 2011
    ..This review provides a cutting edge overview of the current knowledge and underscores the intimate connection between intercellular communication, Ca(2+) signalling and cell death...
  15. pmc Connexin mimetic peptides inhibit Cx43 hemichannel opening triggered by voltage and intracellular Ca2+ elevation
    Nan Wang
    Physiology Group, Department of Basic Medical Sciences, Faculty of Medicine and Health Sciences, Ghent University, Belgium
    Basic Res Cardiol 107:304. 2012
    ..Our results indicate that under pathological conditions, when [Ca(2+)](i) is elevated, Cx43 HC opening is promoted in cardiomyocytes and CxMPs counteract this effect...
  16. ncbi request reprint Photoliberating inositol-1,4,5-trisphosphate triggers ATP release that is blocked by the connexin mimetic peptide gap 26
    Katleen Braet
    Department of Physiology and Pathophysiology, Ghent University, De Pintelaan 185, Block B, Room 306, Ghent B 9000, Belgium
    Cell Calcium 33:37-48. 2003
    ..Photoliberating calcium did not trigger intercellular calcium waves or ATP release. We conclude that InsP(3)-triggered ATP release through connexin hemichannels contributes to the intercellular propagation of calcium signals...
  17. pmc Connexin channels provide a target to manipulate brain endothelial calcium dynamics and blood-brain barrier permeability
    Marijke De Bock
    Department of Basic Medical Sciences, Physiology Group, Ghent University, Ghent, Belgium
    J Cereb Blood Flow Metab 31:1942-57. 2011
    ..We conclude that interfering with endothelial connexin hemichannels is a novel approach to limiting BBB-permeability alterations...
  18. pmc Intracellular calcium changes trigger connexin 32 hemichannel opening
    Elke De Vuyst
    Department of Physiology and Pathophysiology, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium
    EMBO J 25:34-44. 2006
    ..Our results indicate that [Ca2+]i elevation triggers hemichannel opening, and suggest that these channels are under physiological control...
  19. ncbi request reprint Pharmacological sensitivity of ATP release triggered by photoliberation of inositol-1,4,5-trisphosphate and zero extracellular calcium in brain endothelial cells
    Katleen Braet
    Department of Physiology and Pathophysiology, Ghent University, De Pintelaan, Ghent, Belgium
    J Cell Physiol 197:205-13. 2003
    ....
  20. doi request reprint Connexin targeting peptides as inhibitors of voltage- and intracellular Ca2+-triggered Cx43 hemichannel opening
    Nan Wang
    Department of Basic Medical Sciences, Physiology Group, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium
    Neuropharmacology 75:506-16. 2013
    ..This article is part of the Special Issue Section entitled 'Current Pharmacology of Gap Junction Channels and Hemichannels'...
  21. doi request reprint IP3, a small molecule with a powerful message
    Elke Decrock
    Department of Basic Medical Sciences, Ghent University, Ghent, Belgium
    Biochim Biophys Acta 1833:1772-86. 2013
    ..Finally, we highlight several pathological conditions in which anomalous intercellular IP3/Ca(2+) signaling might play a role. This article is part of a Special Issue entitled:12th European Symposium on Calcium...
  22. pmc In situ bipolar electroporation for localized cell loading with reporter dyes and investigating gap junctional coupling
    Elke De Vuyst
    Department of Physiology and Pathophysiology, Faculty of Medicine and Health Sciences, Ghent University, B 9000 Ghent, Belgium
    Biophys J 94:469-79. 2008
    ..We conclude that electroporation loading and dye transfer is a robust technique to investigate gap-junctional coupling that combines minimal cell damage with accurate probing of the degree of cell-cell communication...
  23. pmc Connexin hemichannels and gap junction channels are differentially influenced by lipopolysaccharide and basic fibroblast growth factor
    Elke De Vuyst
    Department of Physiology and Pathophysiology, Faculty of Medicine and Health Sciences, Ghent University, B 9000 Ghent, Belgium
    Mol Biol Cell 18:34-46. 2007
    ....
  24. ncbi request reprint Tumour necrosis factor alpha inhibits purinergic calcium signalling in blood-brain barrier endothelial cells
    Wouter Vandamme
    Department of Physiology and Pathophysiology, Ghent University, Ghent, Belgium
    J Neurochem 88:411-21. 2004
    ..The cytokine thus inhibits connexin-related communication pathways like gap junctions and connexin hemichannels...
  25. doi request reprint L-beta-ODAP alters mitochondrial Ca2+ handling as an early event in excitotoxicity
    Marijke Van Moorhem
    Department of Basic Medical Sciences Physiology group, Faculty of Medicine and Health Sciences, De Pintelaan 185 block B, 3th floor, Ghent University, B 9000 Ghent, Belgium
    Cell Calcium 47:287-96. 2010
    ..We conclude that L-beta-ODAP disturbs the ER-mitochondrial Ca2+ signaling axis and thereby renders the cells more vulnerable to its excitotoxic effects that ultimately will lead to cell death...
  26. doi request reprint (18)F-fluoromethylcholine (FCho), (18)F-fluoroethyltyrosine (FET), and (18)F-fluorodeoxyglucose (FDG) for the discrimination between high-grade glioma and radiation necrosis in rats: a PET study
    Julie Bolcaen
    Department of Nuclear Medicine, Ghent University Hospital, Ghent, Belgium
    Nucl Med Biol 42:38-45. 2015
    ....
  27. ncbi request reprint Electroporation loading and photoactivation of caged InsP3: tools to investigate the relation between cellular ATP release in response to intracellular InsP3 elevation
    Katleen Braet
    Physiology and Pathophysiology, Ghent University, De Pintelaan 185 block B, B 9000 Ghent, Belgium
    J Neurosci Methods 132:81-9. 2004
    ..Our data indicate the involvement of low affinity InsP(3) receptor sites in the pathway leading to triggered ATP release, with activation of these receptors causing the release of 1-2% of the total cellular ATP pool...
  28. ncbi request reprint At the cross-point of connexins, calcium and ATP: blocking hemichannels inhibits vasoconstriction of rat small mesenteric arteries
    Mélissa Bol
    Physiology Group, Dept Basic Medical Sciences, Faculty of Medicine and Health Sciences, Ghent University, 9000 Ghent, Belgium
    Cardiovasc Res . 2016
    ..We applied several peptide modulators of hemichannel function and inhibitors of Ca2+ and ATP signaling to investigate their influence on SMC Ca2+ dynamics and vessel contractility...
  29. doi request reprint Flow cytometric calcium flux assay: evaluation of cytoplasmic calcium kinetics in whole blood leukocytes
    Eva Schepers
    Renal Division, Department of Internal Medicine, University Hospital Gent, De Pintelaan 185, 9000 Gent, Belgium
    J Immunol Methods 348:74-82. 2009
    ..The approach allows to evaluate the effect of various agonists on [Ca(2+)](i) changes in leukocytes, with physiological, patho-physiological or therapeutic purposes...
  30. doi request reprint The dual face of connexin-based astroglial Ca(2+) communication: a key player in brain physiology and a prime target in pathology
    Marijke De Bock
    Department of Basic Medical Sciences, Physiology Group, Faculty of Medicine and Health Sciences, Ghent University, B 9000 Ghent, Belgium
    Biochim Biophys Acta 1843:2211-32. 2014
    ..This article is part of a Special Issue entitled: Calcium signaling in health and disease. Guest Editors: Geert Bultynck, Jacques Haiech, Claus W. Heizmann, Joachim Krebs, and Marc Moreau. ..
  31. ncbi request reprint Calcium signal communication in the central nervous system
    Katleen Braet
    Department of Physiology and Pathophysiology, Ghent University, De Pintelaan 185, B 9000 Ghent, Belgium
    Biol Cell 96:79-91. 2004
    ....
  32. doi request reprint Quantifying hemodynamic refractory bold effects in normal subjects at the single-subject level using an inverse logit fitting procedure
    Benedicte Descamps
    Department of Radiology and Nuclear Medicine, Ghent University, Ghent, Belgium
    J Magn Reson Imaging 35:723-30. 2012
    ..To evaluate whether hemodynamic refractory effects provoked by repeated visual stimulation can be detected and quantified at the single-subject level using a recently described hemodynamic response function (HRF) fitting algorithm...
  33. doi request reprint Connexin and pannexin signaling pathways, an architectural blueprint for CNS physiology and pathology?
    Elke Decrock
    Physiology Group, Department of Basic Medical Sciences, Ghent University, De Pintelaan 185 block B, 3rd Floor, 9000, Ghent, Belgium
    Cell Mol Life Sci 72:2823-51. 2015
    ..By highlighting both physiological and pathological conditions, it becomes evident that Cxs and Panxs can play a dual role in the CNS and that an accurate fine-tuning of each signaling mechanism is crucial for normal CNS physiology...
  34. doi request reprint Electroporation loading and flash photolysis to investigate intra- and intercellular Ca2+ signaling
    Elke Decrock
    Department of Basic Medical Sciences, Physiology Group, Ghent University, 9000 Ghent, Belgium
    Cold Spring Harb Protoc 2015:239-49. 2015
    ..Moreover, the electroporation method allows loading of membrane-impermeable agents that interfere with IP3 and Ca(2+) signaling. ..
  35. doi request reprint Flash photolysis of caged IP3 to trigger intercellular Ca2+ waves
    Elke Decrock
    Department of Basic Medical Sciences, Physiology Group, Ghent University, 9000 Ghent, Belgium
    Cold Spring Harb Protoc 2015:289-92. 2015
    ..This protocol describes cell loading with membrane impermeable caged IP3 and the UV flash illumination procedure. ..
  36. doi request reprint Electroporation loading of membrane-impermeable molecules to investigate intra- and intercellular Ca2+ signaling
    Elke Decrock
    Department of Basic Medical Sciences, Physiology Group, Ghent University, 9000 Ghent, Belgium
    Cold Spring Harb Protoc 2015:284-8. 2015
    ..Here, we describe the detailed procedure of electroporation loading. ..
  37. doi request reprint A new angle on blood-CNS interfaces: a role for connexins?
    Marijke De Bock
    Department of Basic Medical Sciences, Physiology Group, Ghent University, Ghent, Belgium
    FEBS Lett 588:1259-70. 2014
    ..Here, we review current knowledge on the role of Cxs in the BBB, BCSFB and other interfaces that subside within the CNS. We conclude that Cxs are a rather unexplored but promising target for influencing CNS barrier function. ..
  38. ncbi request reprint L-β-N-oxalyl-α,β-diaminopropionic acid toxicity in motor neurons
    Marijke Van Moorhem
    Department of Basic Medical Sciences, Physiology Group, Faculty of Medicine and Health Sciences, Ghent University, Gent, Belgium
    Neuroreport 22:131-5. 2011
    ..Methionine and cysteine were also protective against neuronal cell death. We conclude that deregulation of [Ca2+]i homeostasis and oxidative stress contribute to motor neuron cell death in neurolathyrism...
  39. doi request reprint Into rather unexplored terrain-transcellular transport across the blood-brain barrier
    Marijke De Bock
    Physiology Group, Department of Basic Medical Sciences, Ghent University, Ghent, Belgium
    Glia 64:1097-123. 2016
    ..We conclude that transcytotic events at the BBB, despite being less acknowledged, cannot be simply dismissed as done in the past, but actively contribute to BBB leakage in many different pathologies. GLIA 2016;64:1097-1123. ..
  40. pmc Intracellular Cleavage of the Cx43 C-Terminal Domain by Matrix-Metalloproteases: A Novel Contributor to Inflammation?
    Marijke De Bock
    Physiology Group, Department of Basic Medical Sciences, Ghent University, 9000 Ghent, Belgium
    Mediators Inflamm 2015:257471. 2015
    ..Finally, we set out how aberrant channel function resulting from cleavage can contribute to the acute inflammatory response during tissue injury. ..
  41. doi request reprint MRI-guided 3D conformal arc micro-irradiation of a F98 glioblastoma rat model using the Small Animal Radiation Research Platform (SARRP)
    Julie Bolcaen
    Department of Nuclear Medicine, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium
    J Neurooncol 120:257-66. 2014
    ..H2AX results confirmed the accuracy of dose delivery. This model, which is quite similar to the approach in the clinic, is valid for combined RT and chemotherapy of GB in rats...
  42. pmc Pharmacological modulation of connexin-formed channels in cardiac pathophysiology
    Elke De Vuyst
    Department of Basic Medical Sciences Physiology group, Faculty of Medicine and Health Sciences, Ghent University, Belgium
    Br J Pharmacol 163:469-83. 2011
    ..These agents show an excellent promise for treatment of arrhythmias in patients with ischaemic cardiomyopathy...
  43. doi request reprint Electroporation Loading and Dye Transfer: A Safe and Robust Method to Probe Gap Junctional Coupling
    Elke Decrock
    Physiology Group, Department of Basic Medical Sciences, Ghent University, De Pintelaan 185, Ghent, 9000, Belgium
    Methods Mol Biol 1437:155-69. 2016
    ..Dynamic and quantitative information on gap junctional communication can subsequently be extracted by tracing the intercellular movement of the dye via time-lapse microscopy. ..
  44. ncbi request reprint Technical note: the design of a stereotactic frame for direct MRI-anatomical correlation of the brachial plexus
    Tom Van Hoof
    Department of Human Anatomy, Embryology, Histology and Medical Physics, Faculty of Medicine and Health Sciences, University Ghent, Godshuizenlaan 4, 9000, Ghent, Belgium
    Surg Radiol Anat 27:548-56. 2005
    ..The present study shows that the method is suited for direct MRI-anatomic comparison of the brachial plexus and is also proposed for application to other topographical regions...
  45. ncbi request reprint Gap junctional communication and connexin43 expression in relation to apoptotic cell death and survival of granulosa cells
    Dmitri V Krysko
    Department of Human Anatomy, Embryology, Histology and Medical Physics, Faculty of Medicine, Ghent University, Godshuizenlaan 4, B 9000 Ghent, Belgium
    J Histochem Cytochem 52:1199-207. 2004
    ..Our study supports the hypothesis that gap junctional coupling plays a role in propagating a cell death message and suggests a role for Cx43 expression per se in granulosa cell survival...
  46. ncbi request reprint Method to measure force required to remove Pediculus humanus capitis (Phthiraptera: Pediculidae) eggs from human hair
    Hilde Lapeere
    Department of Dermatology, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    J Med Entomol 42:89-93. 2005
    ..A negative correlation was found between the maximum force exerted and the distance of the nit from the scalp. The method described in this report can be used to determine the in vitro efficacy of various products to remove nits...
  47. doi request reprint Influence of methanandamide and CGRP on potassium currents in smooth muscle cells of small mesenteric arteries
    Mélissa Bol
    Physiology Group, Department of Basic Medical Sciences, Ghent University, UZ blok B, De Pintelaan 185, 9000, Ghent, Belgium
    Pflugers Arch 463:669-77. 2012
    ..Collectively, these data indicate that methanandamide relaxes and hyperpolarizes intact mesenteric vessels by releasing CGRP from perivascular nerves...
  48. doi request reprint Peroxisome proliferator-activated receptor gamma activation alleviates postoperative ileus in mice by inhibition of Egr-1 expression and its downstream target genes
    Ole De Backer
    Heymans Institute of Pharmacology, Ghent University, B 9000 Ghent, Belgium
    J Pharmacol Exp Ther 331:496-503. 2009
    ....
  49. ncbi request reprint High frequency deep brain stimulation in the hippocampus modifies seizure characteristics in kindled rats
    Tine Wyckhuys
    Laboratory for Clinical and Experimental Neurophysiology, Department of Neurology, Ghent University Hospital, De Pintelaan 185, B 9000 Ghent, Belgium
    Epilepsia 48:1543-50. 2007
    ..The target for HFS is the hippocampus, as this structure is often presumed to be the seizure focus in human TLE...
  50. doi request reprint Absence of haemodynamic refractory effects in patients with migraine without aura: an interictal fMRI study
    Benedicte Descamps
    Ghent University, Belgium
    Cephalalgia 31:1220-31. 2011
    ..We hypothesize that there may be interictal haemodynamic abnormalities in migraineurs...
  51. pmc The gap junction cellular internet: connexin hemichannels enter the signalling limelight
    W Howard Evans
    Department of Medical Biochemistry and Immunology and the Wales Heart Research Institute, Cardiff University Medical School, Cardiff CF14 4XN, Wales, UK
    Biochem J 397:1-14. 2006
    ....
  52. doi request reprint Mimetic peptides as blockers of connexin channel-facilitated intercellular communication
    W Howard Evans
    Department of Medical Biochemistry and Immunology, Wales Heart Research Institute Cardiff University Medical School, Heath Park, Cardiff, UK
    Cell Commun Adhes 14:265-73. 2007
    ..A mechanism is proposed to help explain the dual action of connexin mimetic peptides on connexin hemichannels and gap-junctional coupling...
  53. ncbi request reprint Calcium dynamics: spatio-temporal organization from the subcellular to the organ level
    Geneviève Dupont
    Theoretical Chronobiology Unit, Universite Libre de Bruxelles, Faculte des Sciences, 1050 Brussels, Belgium
    Int Rev Cytol 261:193-245. 2007
    ....