Sébastien Santini

Summary

Affiliation: Gembloux Agricultural University
Country: Belgium

Publications

  1. pmc Structural characterization of CA1462, the Candida albicans thiamine pyrophosphokinase
    Sébastien Santini
    Information Genomique et Structurale, UPR2589, Parc Scientifique de Luminy, 13288, Marseille Cedex 09, France
    BMC Struct Biol 8:33. 2008
  2. pmc The conserved Candida albicans CA3427 gene product defines a new family of proteins exhibiting the generic periplasmic binding protein structural fold
    Sébastien Santini
    Information Génomique et Structurale CNRS UPR2589, Aix Marseille Universite, Mediterranean Institute of Microbiology, Parc Scientifique de Luminy, Marseille, France
    PLoS ONE 6:e18528. 2011
  3. doi Characterization of a novel aphid prenyltransferase displaying dual geranyl/farnesyl diphosphate synthase activity
    Sophie Vandermoten
    Gembloux Agricultural University, Department of Functional and Evolutionary Entomology, Passage des Déportés 2, B 5030 Gembloux, Belgium
    FEBS Lett 582:1928-34. 2008
  4. doi Structural features conferring dual geranyl/farnesyl diphosphate synthase activity to an aphid prenyltransferase
    Sophie Vandermoten
    Gembloux Agricultural University, Department of Functional and Evolutionary Entomology, Passage des Déportés 2, Gembloux, Belgium
    Insect Biochem Mol Biol 39:707-16. 2009
  5. pmc Breaking the 1000-gene barrier for Mimivirus using ultra-deep genome and transcriptome sequencing
    Matthieu Legendre
    Structural and genomic Information Laboratory CNRS, UPR2589, Mediterranean Institute of Microbiology, Aix Marseille Universite, 163 Avenue de Luminy, Case 934, FR 13288 Marseille, France
    Virol J 8:99. 2011
  6. ncbi Pathway complexity of Alzheimer's beta-amyloid Abeta16-22 peptide assembly
    Sébastien Santini
    Information Genomique et Structurale, CNRS UPR 2589, 31 Chemin Joseph Aiguier, 13402 Marseille Cedex 20, France
    Structure 12:1245-55. 2004

Collaborators

Detail Information

Publications6

  1. pmc Structural characterization of CA1462, the Candida albicans thiamine pyrophosphokinase
    Sébastien Santini
    Information Genomique et Structurale, UPR2589, Parc Scientifique de Luminy, 13288, Marseille Cedex 09, France
    BMC Struct Biol 8:33. 2008
    ..Since thiamine pyrophosphate is an essential product involved in a variety of metabolic pathways, proteins responsible for its production satisfied these two criteria...
  2. pmc The conserved Candida albicans CA3427 gene product defines a new family of proteins exhibiting the generic periplasmic binding protein structural fold
    Sébastien Santini
    Information Génomique et Structurale CNRS UPR2589, Aix Marseille Universite, Mediterranean Institute of Microbiology, Parc Scientifique de Luminy, Marseille, France
    PLoS ONE 6:e18528. 2011
    ..It was then lost by the Saccharomycetales which include Saccharomyces cerevisiae...
  3. doi Characterization of a novel aphid prenyltransferase displaying dual geranyl/farnesyl diphosphate synthase activity
    Sophie Vandermoten
    Gembloux Agricultural University, Department of Functional and Evolutionary Entomology, Passage des Déportés 2, B 5030 Gembloux, Belgium
    FEBS Lett 582:1928-34. 2008
    ..Analysis of an MpIPPS homology model pointed to substitutions that could confer GPP/FPP synthase activity to the aphid enzyme...
  4. doi Structural features conferring dual geranyl/farnesyl diphosphate synthase activity to an aphid prenyltransferase
    Sophie Vandermoten
    Gembloux Agricultural University, Department of Functional and Evolutionary Entomology, Passage des Déportés 2, Gembloux, Belgium
    Insect Biochem Mol Biol 39:707-16. 2009
    ..Thus the aphid enzyme apparently evolved to maintain the capacity to produce both GPP and FPP through a balance between these mechanisms...
  5. pmc Breaking the 1000-gene barrier for Mimivirus using ultra-deep genome and transcriptome sequencing
    Matthieu Legendre
    Structural and genomic Information Laboratory CNRS, UPR2589, Mediterranean Institute of Microbiology, Aix Marseille Universite, 163 Avenue de Luminy, Case 934, FR 13288 Marseille, France
    Virol J 8:99. 2011
    ..Its 1.2 Mb-genome was initially predicted to encode 917 genes. A subsequent RNA-Seq analysis precisely mapped many transcript boundaries and identified 75 new genes...
  6. ncbi Pathway complexity of Alzheimer's beta-amyloid Abeta16-22 peptide assembly
    Sébastien Santini
    Information Genomique et Structurale, CNRS UPR 2589, 31 Chemin Joseph Aiguier, 13402 Marseille Cedex 20, France
    Structure 12:1245-55. 2004
    ..This indicates that destabilization of alpha-helical intermediates is unlikely to abolish oligomerization of Abeta peptides...