A Deplano

Summary

Country: Belgium

Publications

  1. pmc High interlaboratory reproducibility of DNA sequence-based typing of bacteria in a multicenter study
    M Aires-de-Sousa
    Department of Periodontology, University Hospital Munster, Waldeyerstrasse 30, D 48149 Munster, Germany
    J Clin Microbiol 44:619-21. 2006
  2. ncbi request reprint Outbreak of hospital-adapted clonal complex-17 vancomycin-resistant Enterococcus faecium strain in a haematology unit: role of rapid typing for early control
    A Deplano
    Department of Microbiology, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    J Antimicrob Chemother 60:849-54. 2007
  3. pmc Controlled performance evaluation of the DiversiLab repetitive-sequence-based genotyping system for typing multidrug-resistant health care-associated bacterial pathogens
    Ariane Deplano
    Microbiology Laboratory, Hôpital Erasme Université Libre de Bruxelles, Route de Lennik 808, 1070 Brussels, Belgium
    J Clin Microbiol 49:3616-20. 2011
  4. pmc Molecular characterization of an epidemic clone of panantibiotic-resistant Pseudomonas aeruginosa
    A Deplano
    Department of Microbiology, Hopital Erasme, 808 Route de Lennik, 1070 Brussels, Belgium
    J Clin Microbiol 43:1198-204. 2005
  5. pmc External quality assessment of molecular typing of Staphylococcus aureus isolates by a network of laboratories
    A Deplano
    Laboratoire de Référence MRSA Staphylocoques, Universite Libre de Bruxelles, Service de Microbiologie, Hopital Erasme, 808, Route de Lennik, 1070 Brussels, Belgium
    J Clin Microbiol 44:3236-44. 2006
  6. ncbi request reprint Clonal dissemination of epidemic methicillin-resistant Staphylococcus aureus in Belgium and neighboring countries
    A Deplano
    Laboratoire de Référence MRSA Staphylocoques, Department of Microbiology, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium
    Clin Microbiol Infect 6:239-45. 2000
  7. ncbi request reprint In vivo deletion of the methicillin resistance mec region from the chromosome of Staphylococcus aureus strains
    A Deplano
    Department of Microbiology, Erasme Hospital, Universite Libre de Bruxelles, Route de Lennik 808, B 1070 Brussels, Belgium
    J Antimicrob Chemother 46:617-20. 2000
  8. doi request reprint Evolutionary relationships between sporadic and epidemic strains of healthcare-associated methicillin-resistant Staphylococcus aureus
    M Hallin
    Laboratoire de Référence MRSA Staphylocoques, Department of Microbiology, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium
    Clin Microbiol Infect 14:659-69. 2008
  9. doi request reprint Community-acquired methicillin-resistant Staphylococcus aureus clones circulating in Belgium from 2005 to 2009: changing epidemiology
    J Brauner
    Laboratoire de Référence MRSA Staphylocoques, Service de Microbiologie, Université Libre de Bruxelles ULB Hôpital Erasme, Brussels, Belgium
    Eur J Clin Microbiol Infect Dis 32:613-20. 2013
  10. doi request reprint Previous healthcare exposure is the main antecedent for methicillin-resistant Staphylococcus aureus carriage on hospital admission in Belgium
    S Vandendriessche
    Laboratoire de Référence MRSA Staphylocoques, Department of Microbiology, Hopital Erasme, Universite Libre de Bruxelles, Route de Lennik 808, 1070, Brussels, Belgium
    Eur J Clin Microbiol Infect Dis 31:2283-92. 2012

Collaborators

Detail Information

Publications36

  1. pmc High interlaboratory reproducibility of DNA sequence-based typing of bacteria in a multicenter study
    M Aires-de-Sousa
    Department of Periodontology, University Hospital Munster, Waldeyerstrasse 30, D 48149 Munster, Germany
    J Clin Microbiol 44:619-21. 2006
    ..aureus DNA samples sent to 10 laboratories. Specialized software for automated sequence analysis ensured a common typing nomenclature...
  2. ncbi request reprint Outbreak of hospital-adapted clonal complex-17 vancomycin-resistant Enterococcus faecium strain in a haematology unit: role of rapid typing for early control
    A Deplano
    Department of Microbiology, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    J Antimicrob Chemother 60:849-54. 2007
    ..To describe the investigation and molecular characterization of a vancomycin-resistant Enterococcus faecium (VREF) strain responsible for a nosocomial outbreak in the haematology unit of a tertiary-care university hospital...
  3. pmc Controlled performance evaluation of the DiversiLab repetitive-sequence-based genotyping system for typing multidrug-resistant health care-associated bacterial pathogens
    Ariane Deplano
    Microbiology Laboratory, Hôpital Erasme Université Libre de Bruxelles, Route de Lennik 808, 1070 Brussels, Belgium
    J Clin Microbiol 49:3616-20. 2011
    ..For E. coli and P. aeruginosa, MLST cannot be reliably inferred from DL type due to phylogenetic group violation or discordance...
  4. pmc Molecular characterization of an epidemic clone of panantibiotic-resistant Pseudomonas aeruginosa
    A Deplano
    Department of Microbiology, Hopital Erasme, 808 Route de Lennik, 1070 Brussels, Belgium
    J Clin Microbiol 43:1198-204. 2005
    ..This study illustrates the ability of multiresistant P. aeruginosa to cause an outbreak with significant morbidity and mortality and underscores the need to identify clonal outbreaks, which require targeted infection control measures...
  5. pmc External quality assessment of molecular typing of Staphylococcus aureus isolates by a network of laboratories
    A Deplano
    Laboratoire de Référence MRSA Staphylocoques, Universite Libre de Bruxelles, Service de Microbiologie, Hopital Erasme, 808, Route de Lennik, 1070 Brussels, Belgium
    J Clin Microbiol 44:3236-44. 2006
    ..Our findings indicate that surveys of lab proficiency are useful for validation and optimization of molecular typing services to local hospital infection control programs...
  6. ncbi request reprint Clonal dissemination of epidemic methicillin-resistant Staphylococcus aureus in Belgium and neighboring countries
    A Deplano
    Laboratoire de Référence MRSA Staphylocoques, Department of Microbiology, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium
    Clin Microbiol Infect 6:239-45. 2000
    ..To determine the diversity of pulsed-field gel electrophoresis (PFGE) types among epidemic strains of methicillin-resistant Staphylococcus aureus (MRSA) recovered in Belgium, France, Germany and The Netherlands over the period 1981-94...
  7. ncbi request reprint In vivo deletion of the methicillin resistance mec region from the chromosome of Staphylococcus aureus strains
    A Deplano
    Department of Microbiology, Erasme Hospital, Universite Libre de Bruxelles, Route de Lennik 808, B 1070 Brussels, Belgium
    J Antimicrob Chemother 46:617-20. 2000
    ..The mecA sequence present in the MRSA was absent in the MSSA variant. Therefore, in vivo deletion of the mec region may occur in some lineages of S. aureus more frequently than previously thought...
  8. doi request reprint Evolutionary relationships between sporadic and epidemic strains of healthcare-associated methicillin-resistant Staphylococcus aureus
    M Hallin
    Laboratoire de Référence MRSA Staphylocoques, Department of Microbiology, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium
    Clin Microbiol Infect 14:659-69. 2008
    ..These findings suggest that the SCCmec type and insertion/deletion of other mobile genetic elements may be involved in modulating the epidemic behaviour of MRSA strains of similar genetic background, independently of fitness cost...
  9. doi request reprint Community-acquired methicillin-resistant Staphylococcus aureus clones circulating in Belgium from 2005 to 2009: changing epidemiology
    J Brauner
    Laboratoire de Référence MRSA Staphylocoques, Service de Microbiologie, Université Libre de Bruxelles ULB Hôpital Erasme, Brussels, Belgium
    Eur J Clin Microbiol Infect Dis 32:613-20. 2013
    ..The epidemiology of CA-MRSA in Belgium is changing, as the rapid diffusion of the USA300 clone seems to occur, together with a clonal diversification...
  10. doi request reprint Previous healthcare exposure is the main antecedent for methicillin-resistant Staphylococcus aureus carriage on hospital admission in Belgium
    S Vandendriessche
    Laboratoire de Référence MRSA Staphylocoques, Department of Microbiology, Hopital Erasme, Universite Libre de Bruxelles, Route de Lennik 808, 1070, Brussels, Belgium
    Eur J Clin Microbiol Infect Dis 31:2283-92. 2012
    ..The extra-hospital MRSA reservoir in Belgium mainly consists of persons with previous healthcare exposure. PVL-positive CA-MRSA and LA-MRSA strains remained infrequent among hospitalized patients...
  11. doi request reprint Intensive care unit outbreak of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae controlled by cohorting patients and reinforcing infection control measures
    C Laurent
    Department of Infection Control and Epidemiology, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium
    Infect Control Hosp Epidemiol 29:517-24. 2008
    ....
  12. ncbi request reprint Polyclonal emergence and importation of community-acquired methicillin-resistant Staphylococcus aureus strains harbouring Panton-Valentine leucocidin genes in Belgium
    O Denis
    Laboratoire de Référence MRSA Staphylocoques, Department of Microbiology, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium
    J Antimicrob Chemother 56:1103-6. 2005
    ..The objective of this study was to describe the molecular characteristics of the first PVL-positive MRSA strains isolated in Belgium...
  13. doi request reprint Dynamic pattern and genotypic diversity of Staphylococcus aureus nasopharyngeal carriage in healthy pre-school children
    S Blumental
    Paediatric Infectious Diseases Department, Hopital Universitaire des Enfants Reine Fabiola, Brussels, Belgium
    J Antimicrob Chemother 68:1517-23. 2013
    ..The objectives of this study were to assess the S. aureus temporal carriage pattern among a healthy community of pre-school children, with concomitant description of genotype diversity, toxin-encoding genes and antibiotic resistance...
  14. doi request reprint Heterogeneity of disease and clones of community-onset methicillin-resistant Staphylococcus aureus in children attending a paediatric hospital in Belgium
    A Vergison
    Paediatric Infectious Diseases Unit, Hopital Universitaire des Enfants Reine Fabiola, Universite Libre de Bruxelles, Brussels, Belgium
    Clin Microbiol Infect 18:769-77. 2012
    ..aureus infections. Monitoring of MRSA rates in S. aureus CO infections remains mandatory, and further investigation is warranted to establish the source of colonization in young infants...
  15. pmc Pseudo-outbreak of extremely drug-resistant pseudomonas aeruginosa urinary tract infections due to contamination of an automated urine analyzer
    M Hallin
    Department of Microbiology, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    J Clin Microbiol 50:580-2. 2012
    ..Users of such analyzers should be aware that contamination can occur and should always perform culture either before the processing of the urine sample on the analyzer or on a distinct sample tube...
  16. ncbi request reprint Comparative and library epidemiological typing systems: outbreak investigations versus surveillance systems
    M J Struelens
    Universite Libre de Bruxelles, Belgium
    Infect Control Hosp Epidemiol 19:565-9. 1998
    ..However, interpretation and nomenclature of typing results for large-scale surveillance purposes still require a better understanding of population structure and microevolution of most microbial pathogens...
  17. pmc Validation of pulsed-field gel electrophoresis and spa typing for long-term, nationwide epidemiological surveillance studies of Staphylococcus aureus infections
    M Hallin
    Department of Microbiology, Hopital Erasme, 1070 Brussels, Belgium
    J Clin Microbiol 45:127-33. 2007
    ..We suggest that spa typing, which is a single-locus-based method, should preferably be used in combination with additional markers, such as staphylococcal cassette chromosome mec typing or resistance or virulence gene detection...
  18. pmc Comparative epidemiology of Staphylococcus epidermidis isolates from patients with catheter-related bacteremia and from healthy volunteers
    S Cherifi
    Infection Control Unit, Brugmann University Hospital, Brussels, Belgium
    J Clin Microbiol 51:1541-7. 2013
    ..epidermidis isolates, which were genetically heterogeneous and susceptible to the majority of antibiotics tested. Clinically severe CRBSIs were due to isolates belonging to two closely related MLST types, ST2 and ST54...
  19. ncbi request reprint National survey of molecular epidemiology of Staphylococcus aureus colonization in Belgian cystic fibrosis patients
    A Vergison
    Department of Pediatric Infectious Diseases, Hospital Epidemiology and Infection Control Unit, Universite Libre de Bruxelles, Hôpital des Enfants Reine Fabiola, Brussels, Belgium
    J Antimicrob Chemother 59:893-9. 2007
    ..We conducted a multicentre survey to determine the prevalence of S. aureus and MRSA colonization in Belgian CF patients and characterize the phenotype and clonal distribution of their staphylococcal strains...
  20. ncbi request reprint International dissemination of a high virulence rabbit Staphylococcus aureus clone
    D Vancraeynest
    Department of Pathology, Bacteriology and Poultry Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, and Laboratoire de Microbiologie, Hôpital de Erasme, Brussels, Belgium
    J Vet Med B Infect Dis Vet Public Health 53:418-22. 2006
    ..Furthermore, the results of MLST and spa typing form a basis for international epidemiology of rabbit S. aureus strains, as these DNA sequence-based typing techniques can easily be used for intercentre comparisons...
  21. doi request reprint Positive predictive value of the Xpert MRSA assay diagnostic for universal patient screening at hospital admission: influence of the local ecology
    S Roisin
    Department of Clinical Microbiology and National MRSA Reference Laboratory, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Eur J Clin Microbiol Infect Dis 31:873-80. 2012
    ..The emergence of new SCCmec variants and the presence of MSSA harboring cross-reactive SCCmec-like elements may challenge the successful implementation of such detection systems...
  22. ncbi request reprint Emergence and dissemination of multidrug resistant clones of Pseudomonas aeruginosa producing VIM-2 metallo-beta-lactamase in Belgium
    A Deplano
    Department of Microbiology, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Euro Surveill 12:E070118.2. 2007
  23. ncbi request reprint New phage type among methicillin-resistant Staphylococcus aureus associated with a local outbreak in Belgium during 2002
    C Wildemauwe
    National Phage Typing Reference Centre, Pasteur Institute, Brussels, Belgium
    Clin Microbiol Infect 12:1036-8. 2006
    ..Molecular typing revealed that they belonged to the multiresistant clonal pulsed-field gel electrophoresis (PFGE) type D8. PFGE group D, characterised as genotype ST228-MRSA-I, has been present in Belgian hospitals since 1999...
  24. doi request reprint Trends in production of extended-spectrum beta-lactamases among Enterobacteriaceae of clinical interest: results of a nationwide survey in Belgian hospitals
    H Rodriguez-Villalobos
    Laboratoire de Microbiologie, Hopital Universitaire Erasme, Universite Libre de Bruxelles, B 1070 Brussels, Belgium
    J Antimicrob Chemother 66:37-47. 2011
    ..to assess the frequency and diversity of extended-spectrum β-lactamases (ESBLs) in Enterobacteriaceae isolates in Belgium...
  25. ncbi request reprint Genetic relatedness between methicillin-susceptible and methicillin-resistant Staphylococcus aureus: results of a national survey
    M Hallin
    Laboratoire de Référence MRSA Staphylocoques, Service de Microbiologie, Universite Libre de Bruxelles, Hopital Erasme, 1070 Brussels, Belgium
    J Antimicrob Chemother 59:465-72. 2007
    ..Whether these clones have been imported from abroad or else have arisen locally via staphylococcal cassette chromosome mec (SCCmec) acquisition by successful methicillin-susceptible S. aureus (MSSA) clones is unknown...
  26. doi request reprint Epidemiological investigation of a nosocomial outbreak of multidrug-resistant Corynebacterium striatum at one Belgian university hospital
    A Verroken
    Department of Clinical Microbiology, UCL Saint Luc University Hospital, Brussels, Belgium
    Clin Microbiol Infect 20:44-50. 2014
    ....
  27. doi request reprint Low occurrence of the new species Staphylococcus argenteus in a Staphylococcus aureus collection of human isolates from Belgium
    M A Argudín
    National Reference Centre Staphylococcus aureus, Department of Microbiology, Hopital Erasme, Universite Libre de Bruxelles, Route de Lennik 808, 1070, Brussels, Belgium
    Eur J Clin Microbiol Infect Dis 35:1017-22. 2016
    ..This first Belgian nationwide analysis showed a low occurrence of S. argenteus. Further studies should be conducted to identify the distribution range and the clinical impact of this new species. ..
  28. ncbi request reprint In vitro activity of ceftaroline against clinical Staphylococcus aureus isolates collected during a national survey conducted in Belgian hospitals
    M Angeles Argudín
    National Reference Centre Staphylococcus aureus, Department of Microbiology, Hopital Erasme, Universite Libre de Bruxelles, Route de Lennik 808, 1070 Brussels, Belgium
    J Antimicrob Chemother . 2016
    ..Ceftaroline-resistant isolates were further investigated for their resistance mechanisms...
  29. ncbi request reprint Sequence-based typing of Legionella pneumophila serogroup 1 clinical isolates from Belgium between 2000 and 2010
    E Vekens
    National Reference Centre for Legionella pneumophila, Department of Microbiology and Infection Control, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel VUB, Brussels, Belgium
    Euro Surveill 17:20302. 2012
    ..Two STs, ST880 and ST881, were new to the EWGLI database. In conclusion, we characterised L. pneumophila sg1 isolates with the SBT method, and created a Belgian profile database that will be useful for future epidemiological studies...
  30. ncbi request reprint Polyclonal Staphylococcal endocarditis caused by genetic variability
    J Van Eldere
    Department of Microbiology, Infectious Diseases Research Group, Rega Institute, Katholieke Universiteit Leuven, B 3000 Leuven, Belgium
    Clin Infect Dis 31:24-30. 2000
    ..Therefore, in cases of foreign device-related infections due to coagulase-negative staphylococci, the possibility of polyclonal infection has to be taken into account, particularly as regards differences in antibiotic susceptibility...
  31. doi request reprint Characterisation of Staphylococcus aureus isolates from bloodstream infections, Democratic Republic of the Congo
    S Vandendriessche
    National Reference Centre for Staphylococcus aureus, Laboratory of Microbiology, Universite Libre de Bruxelles ULB, Brussels, Belgium
    Eur J Clin Microbiol Infect Dis . 2017
    ..5% of isolates (88/108, equally represented among MSSA and MRSA). The present study confirms the occurrence of MRSA with high levels of multidrug co-resistance and PVL-positive MSSA among invasive S. aureus isolates in Central Africa...
  32. ncbi request reprint Management of long-term catheter-related Brevibacterium bacteraemia
    I Beukinga
    Department of Microbiology, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Clin Microbiol Infect 10:465-7. 2004
    ..Molecular typing results demonstrated that the recurrent bacteraemia was caused by the same strain. Implanted-device removal may be necessary, in addition to appropriate antibiotics, for successful management of such infections...
  33. ncbi request reprint Staphylococcus aureus carriage among participants at the 13th European Congress of Clinical Microbiology and Infectious Diseases
    E Nulens
    Department of Medical Microbiology, Nijmegen University Centre for Infectious Diseases, University Medical Centre St Radboud, 440 MMB, P O Box 9101, 6500 Nijmegen, The Netherlands
    Eur J Clin Microbiol Infect Dis 24:145-8. 2005
    ..Surprisingly, the rate of methicillin-susceptible Staphylococcus aureus carriage was significantly higher among participants from countries with a low prevalence of MRSA...
  34. pmc Emergence and dissemination of BEL-1-producing Pseudomonas aeruginosa isolates in Belgium
    Pierre Bogaerts
    Antimicrob Agents Chemother 51:1584-5. 2007
  35. ncbi request reprint Prospective evaluation of imipenem/EDTA combined disc and Etest for detection of metallo-beta-lactamase-producing Pseudomonas aeruginosa
    L Berges
    J Antimicrob Chemother 59:812-3. 2007
  36. doi request reprint A novel PSEN2 mutation associated with a peculiar phenotype
    P Piscopo
    Istituto Superiore di Sanita, 00161 Rome, Italy
    Neurology 70:1549-54. 2008
    ..Mutations of presenilin 2 gene are a rare cause of familial Alzheimer disease (AD). We describe an Italian family with hereditary dementia associated with a novel mutation in the presenilin 2 gene...