Stephane De Wit

Summary

Affiliation: CHU Saint-Pierre
Country: Belgium

Publications

  1. pmc Non-AIDS defining cancers in the D:A:D Study--time trends and predictors of survival: a cohort study
    Signe W Worm
    Research Department of Infection and Population Health, University College London, Royal Free Campus, Rowland Hill Street, London NW3 2PF, UK
    BMC Infect Dis 13:471. 2013
  2. pmc Limited cross-border infections in patients newly diagnosed with HIV in Europe
    Dineke Frentz
    Department of Virology, Erasmus Medical Center, Rotterdam, The Netherlands
    Retrovirology 10:36. 2013
  3. pmc HIV-1 V3 envelope deep sequencing for clinical plasma specimens failing in phenotypic tropism assays
    Ina Vandenbroucke
    Tibotec Virco Virology BVBA, Mechelen, Belgium
    AIDS Res Ther 7:4. 2010
  4. pmc Incidence and risk factors for new-onset diabetes in HIV-infected patients: the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) study
    Stephane De Wit
    Centre Hospitalier Universitaire Saint Pierre, Brussels, Belgium
    Diabetes Care 31:1224-9. 2008
  5. doi request reprint High-risk human papillomavirus genotypes distribution in a cohort of HIV-positive women living in Europe: epidemiological implication for vaccination against human papillomavirus
    Deborah Konopnicki
    aDepartment of Infectious Diseases and AIDS Reference CentrebDepartment of Gynaecology, Saint Pierre University HospitalcMolecular Biology LaboratorydDepartment of Pathology, Institut Jules Bordet, Universite Libre de Bruxelles, Brussels, Belgium
    AIDS 30:425-33. 2016
  6. doi request reprint Prolonged antiretroviral therapy is associated with fewer anal high-grade squamous intraepithelial lesions in HIV-positive MSM in a cross-sectional study
    Agnes Libois
    Department of Infectious Diseases, University Saint Pierre Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Sex Transm Infect . 2016
  7. pmc High-risk human papillomavirus infection in HIV-positive African women living in Europe
    Deborah Konopnicki
    Department of Infectious Diseases, Saint Pierre University Hospital, Brussels Free University, Brussels, Belgium
    J Int AIDS Soc 16:18023. 2013
  8. doi request reprint Improvements over time in short-term mortality following myocardial infarction in HIV-positive individuals
    Camilla Ingrid Hatleberg
    aCHIP, Department of Infectious Diseases, section 2100, Rigshospitalet, University of Copenhagen, Copenhagen, DenmarkbICAP Columbia University and Harlem Hospital, New York, USAcResearch Department of Infection and Population Health, UCL, London, UKdDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, SwitzerlandeAcademic Medical Center, Department of Global Health and Division of Infectious Diseases, University of Amsterdam, and HIV Monitoring Foundation, Amsterdam, The NetherlandsfDepartment of Public Health, Nice University Hospital, NicegUniversité de Bordeaux, ISPED, Centre INSERM U897 Epidemiologie Biostatistique, Bordeaux, FrancehThe Kirby Institute, UNSW Australia, Sydney, AustraliaiDipartimento di Scienze della Salute, Clinica di Malattie Infettive e Tropicali, Azienda Ospedaliera Polo Universitario San Paolo, Milan, ItalyjDivision of Infectious Diseases, Saint Pierre University Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    AIDS 30:1583-96. 2016
  9. pmc HIV-Helicobacter pylori Co-Infection: Antibiotic Resistance, Prevalence, and Risk Factors
    Marcel Nkuize
    Department of Gastroenterology and Hepatology, CHU Saint Pierre, Universite Libre de Bruxelles, Brussels, Belgium
    PLoS ONE 10:e0145119. 2015
  10. doi request reprint The role of upper gastrointestinal endoscopy in the era of modern antiretroviral therapy
    Marcel Nkuize
    Departments of aHepatogastroenterology bInfectious Diseases, CHU Saint Pierre, Universite Libre de Bruxelles, Brussels, Belgium
    Eur J Gastroenterol Hepatol 27:1459-65. 2015

Detail Information

Publications25

  1. pmc Non-AIDS defining cancers in the D:A:D Study--time trends and predictors of survival: a cohort study
    Signe W Worm
    Research Department of Infection and Population Health, University College London, Royal Free Campus, Rowland Hill Street, London NW3 2PF, UK
    BMC Infect Dis 13:471. 2013
    ..Using data from a large international cohort of HIV-positive individuals, we described the incidence of NADC from 2004-2010, and described subsequent mortality and predictors of these...
  2. pmc Limited cross-border infections in patients newly diagnosed with HIV in Europe
    Dineke Frentz
    Department of Virology, Erasmus Medical Center, Rotterdam, The Netherlands
    Retrovirology 10:36. 2013
    ..In this study, phylogenetic associations among HIV of newly diagnosed patients were determined across Europe...
  3. pmc HIV-1 V3 envelope deep sequencing for clinical plasma specimens failing in phenotypic tropism assays
    Ina Vandenbroucke
    Tibotec Virco Virology BVBA, Mechelen, Belgium
    AIDS Res Ther 7:4. 2010
    ..The samples were submitted to massive parallel sequencing and to confirmatory recombinant phenotyping using a fraction of the gp120 domain...
  4. pmc Incidence and risk factors for new-onset diabetes in HIV-infected patients: the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) study
    Stephane De Wit
    Centre Hospitalier Universitaire Saint Pierre, Brussels, Belgium
    Diabetes Care 31:1224-9. 2008
    ....
  5. doi request reprint High-risk human papillomavirus genotypes distribution in a cohort of HIV-positive women living in Europe: epidemiological implication for vaccination against human papillomavirus
    Deborah Konopnicki
    aDepartment of Infectious Diseases and AIDS Reference CentrebDepartment of Gynaecology, Saint Pierre University HospitalcMolecular Biology LaboratorydDepartment of Pathology, Institut Jules Bordet, Universite Libre de Bruxelles, Brussels, Belgium
    AIDS 30:425-33. 2016
    ..We aimed to analyse the HRHPV genotype distribution in a cohort of HIV-positive women and to estimate the potential protection offered by the different HPV vaccines...
  6. doi request reprint Prolonged antiretroviral therapy is associated with fewer anal high-grade squamous intraepithelial lesions in HIV-positive MSM in a cross-sectional study
    Agnes Libois
    Department of Infectious Diseases, University Saint Pierre Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Sex Transm Infect . 2016
    ..HIV-positive men who have sex with men (MSM) are at increased risk of anal cancer. We evaluate the risk factors for anal high-grade squamous intraepithelial lesion (HSIL) (the precursor of anal cancer) in HIV-positive MSM...
  7. pmc High-risk human papillomavirus infection in HIV-positive African women living in Europe
    Deborah Konopnicki
    Department of Infectious Diseases, Saint Pierre University Hospital, Brussels Free University, Brussels, Belgium
    J Int AIDS Soc 16:18023. 2013
    ..Cervical infection with high-risk human papillomavirus (HRHPV) induces cervical cancer and is present in 14% of women in Europe. We assessed the prevalence and incidence of cervical HRHPV in a cohort of HIV-positive women living in Belgium...
  8. doi request reprint Improvements over time in short-term mortality following myocardial infarction in HIV-positive individuals
    Camilla Ingrid Hatleberg
    aCHIP, Department of Infectious Diseases, section 2100, Rigshospitalet, University of Copenhagen, Copenhagen, DenmarkbICAP Columbia University and Harlem Hospital, New York, USAcResearch Department of Infection and Population Health, UCL, London, UKdDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, SwitzerlandeAcademic Medical Center, Department of Global Health and Division of Infectious Diseases, University of Amsterdam, and HIV Monitoring Foundation, Amsterdam, The NetherlandsfDepartment of Public Health, Nice University Hospital, NicegUniversité de Bordeaux, ISPED, Centre INSERM U897 Epidemiologie Biostatistique, Bordeaux, FrancehThe Kirby Institute, UNSW Australia, Sydney, AustraliaiDipartimento di Scienze della Salute, Clinica di Malattie Infettive e Tropicali, Azienda Ospedaliera Polo Universitario San Paolo, Milan, ItalyjDivision of Infectious Diseases, Saint Pierre University Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    AIDS 30:1583-96. 2016
    ..This study evaluated changes in short-term mortality after MI in HIV-positive individuals in the D:A:D Study, and investigated possible reasons for any changes seen...
  9. pmc HIV-Helicobacter pylori Co-Infection: Antibiotic Resistance, Prevalence, and Risk Factors
    Marcel Nkuize
    Department of Gastroenterology and Hepatology, CHU Saint Pierre, Universite Libre de Bruxelles, Brussels, Belgium
    PLoS ONE 10:e0145119. 2015
    ..However, prescription of antibiotics to treat or prevent infections in these patients may increase the likelihood of co-infection with antibiotic-resistant species...
  10. doi request reprint The role of upper gastrointestinal endoscopy in the era of modern antiretroviral therapy
    Marcel Nkuize
    Departments of aHepatogastroenterology bInfectious Diseases, CHU Saint Pierre, Universite Libre de Bruxelles, Brussels, Belgium
    Eur J Gastroenterol Hepatol 27:1459-65. 2015
    ..The primary aim of this study was to determine whether lymphocyte T CD4 cell counts were correlated with indications for endoscopy in these patients and with endoscopic diagnosis...
  11. ncbi request reprint Viral load and CD4 cell response to protease inhibitor-containing regimens in subtype B versus non-B treatment-naive HIV-1 patients
    Stephane De Wit
    St Pierre University Hospital, Brussels, Belgium
    AIDS 18:2330-1. 2004
    ..However, there was a significant difference in the median CD4 cell increase at month 24. Whether this is caused by viral or immune factors warrants further investigation...
  12. doi request reprint Downregulation of CD38 activation markers by atorvastatin in HIV patients with undetectable viral load
    Stephane De Wit
    Division of Infectious Diseases, Saint Pierre University Hospital, Brussels, Belgium
    AIDS 25:1332-3. 2011
    ..controls, with no difference in high-sensitivity C-reactive protein (hsCRP) and CD4. These results suggest that atorvastatin reduces the level of immune activation in patients with undetectable viral load...
  13. ncbi request reprint Is systematic screening and treatment for latent tuberculosis infection in HIV patients useful in a low endemic setting?
    Ula Maniewski
    a Division of Infectious Diseases, St Pierre Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Acta Clin Belg . 2016
    ..Our objectives are to evaluate whether a same decline of incidence was seen in our Belgian tertiary center and to evaluate whether systematic screening and prophylaxis of tuberculosis should remain part of routine practice...
  14. pmc Hyponatremia is a marker of disease severity in HIV-infected patients: a retrospective cohort study
    Philippe Braconnier
    Department of Infectious Diseases, AIDS Reference Center, Saint Pierre University Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    BMC Infect Dis 17:98. 2017
    ..Several studies have demonstrated that patients with hyponatremia are at an increased risk of death. We aimed to investigate the prevalence of hyponatremia in the recent cART-era and evaluate its association with mortality...
  15. pmc Cardiovascular risk evaluation of HIV-positive patients in a case-control study: comparison of the D:A:D and Framingham equations
    Samuel Markowicz
    Infectious Diseases, CHU Saint Pierre, Brussels, Belgium
    J Int AIDS Soc 17:19515. 2014
    ..Prevention of CVD is essential as it remains the most common serious non-AIDS event and contributes significantly to all-cause mortality. A cardiovascular risk-assessment model tailored to HIV population is thus essential...
  16. doi request reprint Comparison of demographic characteristics and upper gastrointestinal endoscopy findings in HIV-positive, antiretroviral-treated patients with and without Helicobacter pylori coinfection
    Marcel Nkuize
    Clinic of Hepato gastroenterology, ULB, Brussels, Belgium
    Helicobacter 17:153-9. 2012
    ..Pylori coinfection...
  17. pmc Characteristics of non-AIDS-defining malignancies in the HAART era: a clinico-epidemiological study
    Nicolas Dauby
    Division of Infectious Diseases, CHU St Pierre, Universite Libre de Bruxelles, Brussels, Belgium
    J Int AIDS Soc 14:16. 2011
    ..Non-AIDS-defining malignancies (NADM) are becoming a major cause of mortality in the era of highly active antiretroviral therapy. We wished to investigate the incidence, risks factors and outcome of NADM in an urban cohort...
  18. ncbi request reprint Combination antiretroviral therapy and the risk of myocardial infarction
    Nina Friis-Møller
    N Engl J Med 349:1993-2003. 2003
    ..It remains controversial whether exposure to combination antiretroviral treatment increases the risk of myocardial infarction...
  19. doi request reprint Response to combination antiretroviral therapy: variation by age
    Caroline A Sabin
    AIDS 22:1463-73. 2008
    ..To provide information on responses to combination antiretroviral therapy in children, adolescents and older HIV-infected persons...
  20. pmc Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients enrolled in the D:A:D study: a multi-cohort collaboration
    Caroline A Sabin
    Lancet 371:1417-26. 2008
    ..Our aim was to explore whether exposure to such drugs was associated with an excess risk of myocardial infarction in a large, prospective observational cohort of HIV-infected patients...
  21. ncbi request reprint Class of antiretroviral drugs and the risk of myocardial infarction
    Nina Friis-Møller
    University of Copenhagen, Copenhagen, Denmark
    N Engl J Med 356:1723-35. 2007
    ..We conducted a study to investigate the association of cumulative exposure to protease inhibitors and nonnucleoside reverse-transcriptase inhibitors with the risk of myocardial infarction...
  22. ncbi request reprint Liver-related deaths in persons infected with the human immunodeficiency virus: the D:A:D study
    Rainer Weber
    Division of Infectious Diseases and Hospital Epidemiology, University Hospital, CH 809a Zurich, Switzerland
    Arch Intern Med 166:1632-41. 2006
    ..An increasing proportion of deaths among human immunodeficiency virus (HIV)-infected persons with access to combination antiretroviral therapy (cART) are due to complications of liver diseases...
  23. ncbi request reprint Predictors of hypertension and changes of blood pressure in HIV-infected patients
    Rodolphe Thiebaut
    INSERM E0338 epsilont U593, ISPED, Universite Victor Segalen Bordeaux 2, Bordeaux, France
    Antivir Ther 10:811-23. 2005
    ..We assessed predictors of changes in systolic (SBP) and diastolic (DBP) blood pressure during follow-up and of the development of hypertension in HIV-infected individuals...
  24. ncbi request reprint Is there evidence for an increase in the death rate from liver-related disease in patients with HIV?
    Amanda Mocroft
    Royal Free Centre for HIV Medicine and Dept Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    AIDS 19:2117-25. 2005
    ..Increases in deaths due to liver-related disease (LRD) among HIV-infected individuals have been reported although the influence of combination antiretroviral therapy (cART) on LRD is controversial...
  25. doi request reprint Prevalence and epidemiology of HIV type 1 drug resistance among newly diagnosed therapy-naive patients in Belgium from 2003 to 2006
    Jurgen Vercauteren
    Rega Institute for Medical Research and University Hospitals, Katholieke Universiteit Leuven, Leuven, Belgium
    AIDS Res Hum Retroviruses 24:355-62. 2008
    ..e., zidovudine, lamivudine, and efavirenz. Our results support the implementation of genotypic resistance testing as a standard of care in all treatment-naive patients in Belgium...