Robert Brasseur

Summary

Country: Belgium

Publications

  1. pmc A new in-silico method for determination of helical transmembrane domains based on the PepLook scan: application to IL-2Rβ and IL-2Rγc receptor chains
    Yan Charlois
    Centre de Biophysique Moleculaire Numerique, Gembloux Agro Bio Tech, 5030 Gembloux, Belgium
    BMC Struct Biol 11:26. 2011
  2. doi request reprint Standardized evaluation of protein stability
    Annick Thomas
    CBMN, Gembloux AgroBiotech, ULg, 5030 Gembloux, Belgium
    Biochim Biophys Acta 1804:1265-71. 2010
  3. doi request reprint Realistic modeling approaches of structure-function properties of CPPs in non-covalent complexes
    Annick Thomas
    Gembloux AgroBiotech, ULg, 2 passage des déportés 5030 Gembloux, Belgium
    Biochim Biophys Acta 1798:2217-22. 2010
  4. pmc Analysis of accessible surface of residues in proteins
    Laurence Lins
    Centre de Biophysique Moleculaire Numerique, Faculté des sciences agronomiques de Gembloux, Passage des Déportés 2, 5030 Gembloux, Belgium
    Protein Sci 12:1406-17. 2003
  5. ncbi request reprint Aromatic side-chain interactions in proteins: near- and far-sequence Tyr-X pairs
    Rita Meurisse
    Centre de Biophysique Moleculaire Numerique, Faculté Scientifique Agronomique de Gembloux, Gembloux, Belgium
    Proteins 54:478-90. 2004
  6. ncbi request reprint Mode of membrane interaction and fusogenic properties of a de novo transmembrane model peptide depend on the length of the hydrophobic core
    Aurélien Lorin
    Gembloux Agricultural University, Centre de Biophysique Moleculaire Numerique, B 5030 Gembloux, Belgium
    J Biol Chem 282:18388-96. 2007
  7. ncbi request reprint The minimal fusion peptide of simian immunodeficiency virus corresponds to the 11 first residues of gp32
    Aurélien Lorin
    Gembloux Agricultural University, Centre de Biophysique Moleculaire Numerique, 2 Passage des Deportes, B 5030 Gembloux, Belgium
    J Pept Sci 14:423-8. 2008
  8. doi request reprint Impacts of the carbonyl group location of ester bond on interfacial properties of sugar-based surfactants: experimental and computational evidences
    Hary Razafindralambo
    Unite de Technologie des Industries Agro Alimentaires, Centre de Biophysique Moleculaire Numerique, Faculte Universitaire des Sciences Agronomiques de Gembloux, 2 Passage des Deportes, B 5030 Gembloux, Belgium
    J Phys Chem B 113:8872-7. 2009

Collaborators

  • Rita Meurisse
  • Annick Thomas
  • Laurence Lins
  • Aurélien Lorin
  • Yan Charlois
  • Hary Razafindralambo
  • Benoit Charloteaux
  • Jean Marc Crowet
  • Claude Deroanne
  • Christophe Blecker
  • Samir Mezdour
  • Michel Paquot
  • Vincent Stroobant
  • Yael Fridmann-Sirkis
  • Yechiel Shai

Detail Information

Publications8

  1. pmc A new in-silico method for determination of helical transmembrane domains based on the PepLook scan: application to IL-2Rβ and IL-2Rγc receptor chains
    Yan Charlois
    Centre de Biophysique Moleculaire Numerique, Gembloux Agro Bio Tech, 5030 Gembloux, Belgium
    BMC Struct Biol 11:26. 2011
    ..To solve this problem, we developed a new modeling procedure using the PepLook method. We scanned the sequences by modeling peptides from the target sequence with a window of 19 residues...
  2. doi request reprint Standardized evaluation of protein stability
    Annick Thomas
    CBMN, Gembloux AgroBiotech, ULg, 5030 Gembloux, Belgium
    Biochim Biophys Acta 1804:1265-71. 2010
    ..The approach opens to possibilities of evaluating any 3D model and of detecting functional residues and should help in conducting mutation assays...
  3. doi request reprint Realistic modeling approaches of structure-function properties of CPPs in non-covalent complexes
    Annick Thomas
    Gembloux AgroBiotech, ULg, 2 passage des déportés 5030 Gembloux, Belgium
    Biochim Biophys Acta 1798:2217-22. 2010
    ..We here discuss bases of realistic in silico molecular modeling approaches of the formation of non-covalent complexes considering CPPs and cargo diversities...
  4. pmc Analysis of accessible surface of residues in proteins
    Laurence Lins
    Centre de Biophysique Moleculaire Numerique, Faculté des sciences agronomiques de Gembloux, Passage des Déportés 2, 5030 Gembloux, Belgium
    Protein Sci 12:1406-17. 2003
    ..This results in a patchwork surface of hydrophobic and hydrophilic areas, which could be important for protein interactions and/or activity...
  5. ncbi request reprint Aromatic side-chain interactions in proteins: near- and far-sequence Tyr-X pairs
    Rita Meurisse
    Centre de Biophysique Moleculaire Numerique, Faculté Scientifique Agronomique de Gembloux, Gembloux, Belgium
    Proteins 54:478-90. 2004
    ..Unlike the His-X pairs, the interactions of the hetroatom in Tyr-X pairs are only favored with a sequence position +4 and over, owing to the spatial accessibility of the heteroatom...
  6. ncbi request reprint Mode of membrane interaction and fusogenic properties of a de novo transmembrane model peptide depend on the length of the hydrophobic core
    Aurélien Lorin
    Gembloux Agricultural University, Centre de Biophysique Moleculaire Numerique, B 5030 Gembloux, Belgium
    J Biol Chem 282:18388-96. 2007
    ..We propose that fusogenicity depends not only on peptide insertion but also on the ability of peptides to destabilize the two leaflets of the liposome membrane...
  7. ncbi request reprint The minimal fusion peptide of simian immunodeficiency virus corresponds to the 11 first residues of gp32
    Aurélien Lorin
    Gembloux Agricultural University, Centre de Biophysique Moleculaire Numerique, 2 Passage des Deportes, B 5030 Gembloux, Belgium
    J Pept Sci 14:423-8. 2008
    ..These results are another piece of evidence that the tilted properties of FPs are important for the fusion process and that our method can be used to predict the minimal FPs of other viruses...
  8. doi request reprint Impacts of the carbonyl group location of ester bond on interfacial properties of sugar-based surfactants: experimental and computational evidences
    Hary Razafindralambo
    Unite de Technologie des Industries Agro Alimentaires, Centre de Biophysique Moleculaire Numerique, Faculte Universitaire des Sciences Agronomiques de Gembloux, 2 Passage des Deportes, B 5030 Gembloux, Belgium
    J Phys Chem B 113:8872-7. 2009
    ..All of the results are supported by the minimum cross-sectional area values per molecule determined by both experimental and computational approaches...