Mohammad Barzegar-Jalali

Summary

Publications

  1. ncbi request reprint Kinetic analysis of drug release from nanoparticles
    Mohammad Barzegar-Jalali
    Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    J Pharm Pharm Sci 11:167-77. 2008
  2. ncbi request reprint Kinetic analysis of chlorpropamide dissolution from solid dispersions
    Mohammad Barzegar-Jalali
    Department of Pharmaceutics, School of Pharmacy and Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    Drug Dev Ind Pharm 33:63-70. 2007
  3. ncbi request reprint Evaluation of in vitro-in vivo correlation and anticonvulsive effect of carbamazepine after cogrinding with microcrystalline cellulose
    Mohammad Barzegar-Jalali
    Department of Pharmaceutics, Faculty of Pharmacy and Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    J Pharm Pharm Sci 9:307-16. 2006
  4. ncbi request reprint Piroxicam nanoparticles for ocular delivery: physicochemical characterization and implementation in endotoxin-induced uveitis
    Khosro Adibkia
    Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Tabriz, Iran
    J Drug Target 15:407-16. 2007
  5. ncbi request reprint Preparation and characterization of solid dispersions of piroxicam with hydrophilic carriers
    Hadi Valizadeh
    Department of Pharmaceutics, Tabriz University of Medical Sciences, Tabriz, Iran
    Drug Dev Ind Pharm 33:45-56. 2007
  6. ncbi request reprint Reciprocal powered time model for release kinetic analysis of ibuprofen solid dispersions in oleaster powder, microcrystalline cellulose and crospovidone
    Ghobad Mohammadi
    Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    J Pharm Pharm Sci 13:152-61. 2010
  7. ncbi request reprint Inhibition of endotoxin-induced uveitis by methylprednisolone acetate nanosuspension in rabbits
    Khosro Adibkia
    Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Tabriz, Iran
    J Ocul Pharmacol Ther 23:421-32. 2007
  8. ncbi request reprint Predicting human intestinal permeability using single-pass intestinal perfusion in rat
    Parvin Zakeri-Milani
    Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    J Pharm Pharm Sci 10:368-79. 2007
  9. ncbi request reprint Quantitative structure-pharmacokinetic relationship modelling: apparent volume of distribution
    Taravat Ghafourian
    Tabriz University of Medical Sciences, Tabriz 51664, Iran
    J Pharm Pharmacol 56:339-50. 2004
  10. doi request reprint Development of azithromycin-PLGA nanoparticles: physicochemical characterization and antibacterial effect against Salmonella typhi
    Ghobad Mohammadi
    Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Colloids Surf B Biointerfaces 80:34-9. 2010

Collaborators

Detail Information

Publications37

  1. ncbi request reprint Kinetic analysis of drug release from nanoparticles
    Mohammad Barzegar-Jalali
    Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    J Pharm Pharm Sci 11:167-77. 2008
    ..Theoretical justification for the two best general models was also provided for the first time...
  2. ncbi request reprint Kinetic analysis of chlorpropamide dissolution from solid dispersions
    Mohammad Barzegar-Jalali
    Department of Pharmaceutics, School of Pharmacy and Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    Drug Dev Ind Pharm 33:63-70. 2007
    ..There was a quantitative relation between the model parameter and the ratio of carrier to drug which could be of value in dissolution rate prediction...
  3. ncbi request reprint Evaluation of in vitro-in vivo correlation and anticonvulsive effect of carbamazepine after cogrinding with microcrystalline cellulose
    Mohammad Barzegar-Jalali
    Department of Pharmaceutics, Faculty of Pharmacy and Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    J Pharm Pharm Sci 9:307-16. 2006
    ..A cogrinding technique was used to increase the dissolution, serum concentrations and anticonvulsive effect of the drug. A novel deconvolution technique of in vitro in vivo correlation was evaluated...
  4. ncbi request reprint Piroxicam nanoparticles for ocular delivery: physicochemical characterization and implementation in endotoxin-induced uveitis
    Khosro Adibkia
    Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Tabriz, Iran
    J Drug Target 15:407-16. 2007
    ..Upon these findings, we propose that the piroxicam:Eudragit RS100 nanosuspensions may be considered as an improved ocular delivery system for locally inhibition of inflammation...
  5. ncbi request reprint Preparation and characterization of solid dispersions of piroxicam with hydrophilic carriers
    Hadi Valizadeh
    Department of Pharmaceutics, Tabriz University of Medical Sciences, Tabriz, Iran
    Drug Dev Ind Pharm 33:45-56. 2007
    ..Data from the X-ray diffraction and FT-IR spectroscopy showed that piroxicam was amorphous in the solid dispersions prepared with dextrin and Eudragit E100...
  6. ncbi request reprint Reciprocal powered time model for release kinetic analysis of ibuprofen solid dispersions in oleaster powder, microcrystalline cellulose and crospovidone
    Ghobad Mohammadi
    Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    J Pharm Pharm Sci 13:152-61. 2010
    ....
  7. ncbi request reprint Inhibition of endotoxin-induced uveitis by methylprednisolone acetate nanosuspension in rabbits
    Khosro Adibkia
    Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Tabriz, Iran
    J Ocul Pharmacol Ther 23:421-32. 2007
    ....
  8. ncbi request reprint Predicting human intestinal permeability using single-pass intestinal perfusion in rat
    Parvin Zakeri-Milani
    Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    J Pharm Pharm Sci 10:368-79. 2007
    ..The aim of the study was the prediction of human intestinal permeability and fraction absorbed of oral dose using single-pass intestinal perfusion technique (SPIP) in rats...
  9. ncbi request reprint Quantitative structure-pharmacokinetic relationship modelling: apparent volume of distribution
    Taravat Ghafourian
    Tabriz University of Medical Sciences, Tabriz 51664, Iran
    J Pharm Pharmacol 56:339-50. 2004
    ..01 for Vd compared with 2.28 for unbound Vd). Moreover, the separation of the compounds into acids and bases did not reduce the prediction error significantly...
  10. doi request reprint Development of azithromycin-PLGA nanoparticles: physicochemical characterization and antibacterial effect against Salmonella typhi
    Ghobad Mohammadi
    Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Colloids Surf B Biointerfaces 80:34-9. 2010
    ..In conclusion, the azithromycin nanoparticle preparations showed appropriate physicochemical and improved antimicrobial properties which can be useful for oral administration...
  11. doi request reprint Evaluation of physicochemical properties and in vivo efficiency of atorvastatin calcium/ezetimibe solid dispersions
    Azin Jahangiri
    Drug Applied Research Center, and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran Students Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
    Eur J Pharm Sci 82:21-30. 2016
    ..According to the obtained results, ATV/EZT SD with improved physicochemical characteristics, showed favorable effects on the serum lipid levels and liver steatosis. ..
  12. doi request reprint Methylprednisolone acetate-Eudragit® RS100 electrospuns: Preparation and physicochemical characterization
    Nazila Jafari-Aghdam
    a Drug Applied Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Artif Cells Nanomed Biotechnol 44:497-503. 2016
    ..75 indicating the diffusion mechanism of drug release. In conclusion, electrospinning could be considered as a simple and cost effective method for fabricating the drug: polymer nanofibers and nanobeads. ..
  13. doi request reprint Evaluation of drug release kinetics and physico-chemical characteristics of metronidazole floating beads based on calcium silicate and gas-forming agents
    Yousef Javadzadeh
    Faculty of Pharmacy and Drug Applied Research Centre, Tabriz University of Medical Sciences, Tabriz, Iran
    Pharm Dev Technol 15:329-38. 2010
    ..50, 5.30 and 7.76. By and large, these systems can float in the gastric condition and control the drug release from the beads...
  14. doi request reprint Application of Box-Behnken design to prepare gentamicin-loaded calcium carbonate nanoparticles
    Solmaz Maleki Dizaj
    a Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Science, Tabriz, Iran
    Artif Cells Nanomed Biotechnol 44:1475-81. 2016
    ..80%. It was concluded that the chemical precipitation technique, together with the Box-Behnken experimental design methodology, could be successfully used to optimize the formulation of drug-incorporated calcium carbonate nanoparticles. ..
  15. ncbi request reprint Propranolol hydrochloride osmotic capsule with controlled onset of release
    Mohammad Barzegar-Jalali
    Department of Pharmaceutics, School of Pharmacy, and Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    Drug Deliv 14:461-8. 2007
    ..2, 4.8, 5.9, 5.5, 7.5, 5.0, 7.8 and 10.5 hr could be of use for either chronotherapeutic purposes in protection of patients against heart attacks and strokes during early morning hours or reducing daily frequency of dosage...
  16. doi request reprint Biopharmaceutical classification of drugs using intrinsic dissolution rate (IDR) and rat intestinal permeability
    Parvin Zakeri-Milani
    Department of Pharmaceutics, Tabriz University of Medical Sciences, Tabriz, Iran
    Eur J Pharm Biopharm 73:102-6. 2009
    ..7 x 10(-5) (cm/s), IDR<1(mg/min/cm(2)). According to the results obtained and proposed classification of drugs, it is concluded that drugs could be categorized correctly based on their IDR and intestinal permeability values...
  17. doi request reprint Methylprednisolone acetate-loaded hydroxyapatite nanoparticles as a potential drug delivery system for treatment of rheumatoid arthritis: In vitro and in vivo evaluations
    Samira Jafari
    Research Center for Pharmaceutical Nanotechnology and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
    Eur J Pharm Sci 91:225-35. 2016
    ..Interestingly, the in vivo study confirmed that the drug-loaded nanoparticles could considerably decrease the paw volume and normalize the hematological abnormalities in the arthritic rats. ..
  18. doi request reprint Development of amitriptyline buccoadhesive tablets for management of pain in dental procedures
    Sara Movassaghian
    Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Drug Dev Ind Pharm 37:849-54. 2011
    ..It is suggested that applying the topical AM mucoadhesive tablet containing the low amount of drug is a safe and promising alternative to relief the pain in the buccal region...
  19. doi request reprint Hydrogel nanoparticles and nanocomposites for nasal drug/vaccine delivery
    Sara Salatin
    Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Science, Tabriz, Iran
    Arch Pharm Res 39:1181-92. 2016
    ..This update review discusses the possible benefits of using hydrogel polymer-based nanoparticles and hydrogel nanocomposites for drug/vaccine delivery through the intranasal administration. ..
  20. ncbi request reprint Ciprofloxacin HCl-loaded calcium carbonate nanoparticles: preparation, solid state characterization, and evaluation of antimicrobial effect against Staphylococcus aureus
    Solmaz Maleki Dizaj
    a Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Tabriz, Iran
    Artif Cells Nanomed Biotechnol . 2016
    ..The drug-loaded nanoparticles showed similar MICs against S. aureus compared to untreated drug. However, a preserved antimicrobial effect was observed for drug-loaded nanoparticles compared to untreated drug after 2 days of incubation...
  21. ncbi request reprint Physicochemical characterization of atorvastatin calcium/ezetimibe amorphous nano-solid dispersions prepared by electrospraying method
    Azin Jahangiri
    a Drug Applied Research Center, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Artif Cells Nanomed Biotechnol . 2016
    ..Since the electrospraying method benefits from the both amorphization and nanosizing effect, this novel approach seems to be an efficient method for the fabrication of N-SDs of poorly water-soluble drugs...
  22. ncbi request reprint Enhancing dissolution, serum concentrations and hypoglycemic effect of glibenclamide using solvent deposition technique
    Siavoush Dastmalchi
    Department of Medicinal Chemistry, School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    J Pharm Pharm Sci 8:175-81. 2005
    ..Therefore, to enhance the drug dissolution, serum concentrations and its hypoglycemic effects, it was formulated as solid dispersions and evaluated the relevant in vitro and in vivo parameters...
  23. ncbi request reprint QSPR models for the prediction of apparent volume of distribution
    Taravat Ghafourian
    Drug Design and Chemometrics Laboratory, Drug Applied Research Centre and School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Int J Pharm 319:82-97. 2006
    ..The structural descriptors in the model can be interpreted based on the known mechanisms of distribution and the molecular structures of the drugs...
  24. pmc Design of eudragit RL nanoparticles by nanoemulsion method as carriers for ophthalmic drug delivery of ketotifen fumarate
    Saieede Soltani
    Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
    Iran J Basic Med Sci 19:550-60. 2016
    ..Ocular nanoparticles were prepared with the objective of reducing the frequency of administration and obtaining controlled release to improve the anti-inflammatory drug delivery...
  25. doi request reprint Calcium carbonate nanoparticles as cancer drug delivery system
    Solmaz Maleki Dizaj
    a 1 Tabriz University of Medical Sciences, Student Research Committee, Faculty of Pharmacy, Tabriz, Iran
    Expert Opin Drug Deliv 12:1649-60. 2015
    ..Also, due to the slow degradation of CaCO3 matrices, these nanoparticles can be used as sustained release systems to retain drugs in cancer tissues for longer times after administration...
  26. doi request reprint Physicochemical characterization and pharmacological evaluation of ezetimibe-PVP K30 solid dispersions in hyperlipidemic rats
    Azin Jahangiri
    Drug Applied Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran Students Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
    Colloids Surf B Biointerfaces 134:423-30. 2015
    ..In the present study, we demonstrated that the SDs of EZT with improved physicochemical characteristics had favorable effects on liver steatosis, liver index and serum lipid levels in the high fat diet-induced hyperlipidemic rats. ..
  27. doi request reprint Physicochemical characterization and in vivo evaluation of triamcinolone acetonide-loaded hydroxyapatite nanocomposites for treatment of rheumatoid arthritis
    Samira Jafari
    Research Center for Pharmaceutical Nanotechnology and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
    Colloids Surf B Biointerfaces 140:223-32. 2016
    ..Therefore, TA-loaded HAp nanocomposites are potentially suggested for treatment of rheumatoid arthritis after further required evaluations...
  28. doi request reprint Inclusion of piroxicam in mesoporous phosphate glass-ceramic and evaluation of the physiochemical characteristics
    Yousef Javadzadeh
    Drug Applied Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Colloids Surf B Biointerfaces 116:751-6. 2014
    ..4-0.7 signifying the Fickian diffusion of PX from the GC. Accordingly, the GC could be considered as a suitable adsorbent to develop an oral drug delivery system. ..
  29. doi request reprint Effect of solvent type on retardation properties of diltiazem HCl form liquisolid tablets
    Khosro Adibkia
    Drug Applied Research Centre and Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz 51664, Iran Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz 51664, Iran
    Colloids Surf B Biointerfaces 113:10-4. 2014
    ..Amorphous form was obtained during the process of liquisolid formulation. It follows that the optimized new technique can be used to prepare sustained release formulations of water-soluble drugs. ..
  30. pmc Design and evaluation of 1- and 3-layer matrices of verapamil hydrochloride for sustaining its release
    Mohammad Reza Siahi
    Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz 51664, Iran
    AAPS PharmSciTech 6:E626-32. 2005
    ....
  31. pmc Nanovaccine for leishmaniasis: preparation of chitosan nanoparticles containing Leishmania superoxide dismutase and evaluation of its immunogenicity in BALB/c mice
    Mohammad Ali Danesh-Bahreini
    Department of Pharmaceutics, School of Pharmacy, Tabriz University of Medical Science, Tabriz, Iran
    Int J Nanomedicine 6:835-42. 2011
    ..Although several chemotherapeutic agents have been used for treating the disease, long-term therapy, limited efficacy and the development of drug-resistant parasites remain the major limitations...
  32. pmc Comparison of Different Nanosuspensions as Potential Ophthalmic Delivery Systems for Ketotifen Fumarate
    Saieede Soltani
    Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
    Adv Pharm Bull 6:345-352. 2016
    ..b>Conclusion: It is concluded that both NSP and NSE provide a useful dosage form for the ocular drug delivery which can enhance the permeability of KF...
  33. doi request reprint Crystal-liquid Fugacity Ratio as a Surrogate Parameter for Intestinal Permeability
    Parvin Zakeri-Milani
    Liver and Gastrointestinal Diseases Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    J Pharm Pharm Sci 19:312-324. 2016
    ..We assessed the feasibility of using crystal-liquid fugacity ratio (CLFR) as an alternative parameter for intestinal permeability in the biopharmaceutical classification (BCS) of passively absorbed drugs...
  34. doi request reprint Antimicrobial activity of the metals and metal oxide nanoparticles
    Solmaz Maleki Dizaj
    Drug Applied Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Mater Sci Eng C Mater Biol Appl 44:278-84. 2014
    ..However, further studies should be performed to minimize the toxicity of metal and metal oxide nanoparticles to apply as proper alternatives for antibiotics and disinfectants especially in biomedical applications. ..
  35. ncbi request reprint Simultaneous determination of naproxen, ketoprofen and phenol red in samples from rat intestinal permeability studies: HPLC method development and validation
    Parvin Zakeri-Milani
    Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    J Pharm Biomed Anal 39:624-30. 2005
    ..36 and 101.6%. Using the SPIP technique and the suggested HPLC method for sample analysis, the mean values of 1.17e(-4) (+/-0.28) cm/s and 0.97e(-4) (+/-0.2) cm/s were obtained for naproxen and ketoprofen, respectively...
  36. ncbi request reprint The effect of type and concentration of vehicles on the dissolution rate of a poorly soluble drug (indomethacin) from liquisolid compacts
    Ali Nokhodchi
    Department of Pharmacy, School of Health and Life Sciences, King s College London, London, United Kingdom
    J Pharm Pharm Sci 8:18-25. 2005
    ..The object of the present study is to increase dissolution rate of indomethacin using liquisolid compacts...
  37. ncbi request reprint A new solution for a chronic problem; aqueous enteric coating
    Hasan Rafati
    Medicinal Plants and Drugs Research Institute MPDRI, Shahid Beheshti University, Evin 19835 389, Tehran, Iran
    J Pharm Sci 95:2432-7. 2006
    ..The enteric tablets maintain their shapes in acid medium and passed the USP dissolution test for DR ASA tablets...