Munirul Alam

Summary

Affiliation: International Centre for Diarrhoeal Disease Research
Country: Bangladesh

Publications

  1. ncbi request reprint Phenotypic and molecular characteristics of Escherichia coli isolated from aquatic environment of Bangladesh
    Munirul Alam
    Laboratory of Enteric Microbiology, Laboratory Sciences Division, International Center for Diarrhoeal Disease Research, Bangladesh, Mohakhali, Dhaka 1212, Bangladesh
    Microbiol Immunol 50:359-70. 2006
  2. pmc Viable but nonculturable Vibrio cholerae O1 in biofilms in the aquatic environment and their role in cholera transmission
    Munirul Alam
    International Center for Diarrhoeal Disease Research, Bangladesh, Dhaka 1000, Bangladesh
    Proc Natl Acad Sci U S A 104:17801-6. 2007
  3. doi request reprint Biofilms in water, its role and impact in human disease transmission
    Anwar Huq
    University of Maryland, Maryland Pathogen Research Institute, 3132 Bioscience Research, Building 413, College Park, MD 20742, United States
    Curr Opin Biotechnol 19:244-7. 2008
  4. pmc Diagnostic limitations to accurate diagnosis of cholera
    Munirul Alam
    Enteric and Food Microbiology Laboratory, Laboratory Sciences Division, International Center for Diarrheal Disease Research, Bangladesh, Dhaka, Bangladesh
    J Clin Microbiol 48:3918-22. 2010
  5. pmc Cholera outbreaks (2012) in three districts of Nepal reveal clonal transmission of multi-drug resistant Vibrio cholerae O1
    Sameer M Dixit
    International Centre for Diarrheal Disease Research, GPO Box 128, 1000 Dhaka, Bangladesh
    BMC Infect Dis 14:392. 2014
  6. pmc Gut microbiota of healthy and malnourished children in bangladesh
    Shirajum Monira
    International Center for Diarrhoeal Disease Research Dhaka, Bangladesh
    Front Microbiol 2:228. 2011
  7. ncbi request reprint Proteolytic activation of Vibrio mimicus (Vm) major outer membrane protein haemagglutinin (HA) with Vm-HA/protease: Implication for understanding bacterial adherence
    Munirul Alam
    Laboratory of Enteric Microbiology, International Center for Diarrhoeal Disease Research, Dhaka, Bangladesh
    Microbiol Immunol 50:845-50. 2006
  8. pmc Genetic characteristics of drug-resistant Vibrio cholerae O1 causing endemic cholera in Dhaka, 2006-2011
    Shah M Rashed
    International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    J Med Microbiol 61:1736-45. 2012
  9. pmc Serogroup, virulence, and genetic traits of Vibrio parahaemolyticus in the estuarine ecosystem of Bangladesh
    Munirul Alam
    International Center for Diarrhoeal Disease Research, Bangladesh, Mohakhali, Dhaka 1212, Bangladesh
    Appl Environ Microbiol 75:6268-74. 2009
  10. pmc Vibrio cholerae classical biotype strains reveal distinct signatures in Mexico
    Munirul Alam
    International Center for Diarrheal Disease Research, Bangladesh, Dhaka, Bangladesh
    J Clin Microbiol 50:2212-6. 2012

Collaborators

Detail Information

Publications36

  1. ncbi request reprint Phenotypic and molecular characteristics of Escherichia coli isolated from aquatic environment of Bangladesh
    Munirul Alam
    Laboratory of Enteric Microbiology, Laboratory Sciences Division, International Center for Diarrhoeal Disease Research, Bangladesh, Mohakhali, Dhaka 1212, Bangladesh
    Microbiol Immunol 50:359-70. 2006
    ..Finally, it may be concluded that serotype-based pathotyping may be useful for E. coli strains of clinical origin; however, it is not precise enough for reliably identifying environmental strains as diarrheagenic...
  2. pmc Viable but nonculturable Vibrio cholerae O1 in biofilms in the aquatic environment and their role in cholera transmission
    Munirul Alam
    International Center for Diarrhoeal Disease Research, Bangladesh, Dhaka 1000, Bangladesh
    Proc Natl Acad Sci U S A 104:17801-6. 2007
    ..cholerae cells freshly discharged into the environment are significantly less robust than cells adapted to environmental conditions...
  3. doi request reprint Biofilms in water, its role and impact in human disease transmission
    Anwar Huq
    University of Maryland, Maryland Pathogen Research Institute, 3132 Bioscience Research, Building 413, College Park, MD 20742, United States
    Curr Opin Biotechnol 19:244-7. 2008
    ..For this reason discovery and investigation of this important bacterial ecological niche in the environment were impeded...
  4. pmc Diagnostic limitations to accurate diagnosis of cholera
    Munirul Alam
    Enteric and Food Microbiology Laboratory, Laboratory Sciences Division, International Center for Diarrheal Disease Research, Bangladesh, Dhaka, Bangladesh
    J Clin Microbiol 48:3918-22. 2010
    ..cholerae by in vivo vibriolytic action of the phage and/or nonculturability induced as a host response...
  5. pmc Cholera outbreaks (2012) in three districts of Nepal reveal clonal transmission of multi-drug resistant Vibrio cholerae O1
    Sameer M Dixit
    International Centre for Diarrheal Disease Research, GPO Box 128, 1000 Dhaka, Bangladesh
    BMC Infect Dis 14:392. 2014
    ..This study was designed to understand the drug response patterns, source, and transmission of Vibrio cholerae associated with 2012 cholera outbreaks in Nepal...
  6. pmc Gut microbiota of healthy and malnourished children in bangladesh
    Shirajum Monira
    International Center for Diarrhoeal Disease Research Dhaka, Bangladesh
    Front Microbiol 2:228. 2011
    ..The predominance of potentially pathogenic Proteobacteria and minimal level of Bacteroidetes as commensal microbiota might be associated to the ill health of malnourished children in Bangladesh...
  7. ncbi request reprint Proteolytic activation of Vibrio mimicus (Vm) major outer membrane protein haemagglutinin (HA) with Vm-HA/protease: Implication for understanding bacterial adherence
    Munirul Alam
    Laboratory of Enteric Microbiology, International Center for Diarrhoeal Disease Research, Dhaka, Bangladesh
    Microbiol Immunol 50:845-50. 2006
    ..mimicus strains. Proteolytic activation of OMPHA was also achieved with various proteases from bacterial and eukaryotic sources. These findings may indicate a novel coordination of V. mimicus HAs in the adherence of the bacterium...
  8. pmc Genetic characteristics of drug-resistant Vibrio cholerae O1 causing endemic cholera in Dhaka, 2006-2011
    Shah M Rashed
    International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    J Med Microbiol 61:1736-45. 2012
    ..cholerae strains were clonal, as determined by a PFGE (NotI)-based dendrogram. This study shows 2008-2010 to be the time of transition from ctxB genotype 1 to genotype 7 in V. cholerae ET causing endemic cholera in Dhaka, Bangladesh...
  9. pmc Serogroup, virulence, and genetic traits of Vibrio parahaemolyticus in the estuarine ecosystem of Bangladesh
    Munirul Alam
    International Center for Diarrhoeal Disease Research, Bangladesh, Mohakhali, Dhaka 1212, Bangladesh
    Appl Environ Microbiol 75:6268-74. 2009
    ..The demonstrated prevalence of tdh-positive and diarrheagenic serogroup O8:K21 strains in coastal villages of Bangladesh indicates a significant human health risk for inhabitants...
  10. pmc Vibrio cholerae classical biotype strains reveal distinct signatures in Mexico
    Munirul Alam
    International Center for Diarrheal Disease Research, Bangladesh, Dhaka, Bangladesh
    J Clin Microbiol 50:2212-6. 2012
    ....
  11. pmc Cholera between 1991 and 1997 in Mexico was associated with infection by classical, El Tor, and El Tor variants of Vibrio cholerae
    Munirul Alam
    International Center for Diarrhoeal Disease Research, Bangladesh ICDDR, B, Mohakhali, Dhaka, Bangladesh
    J Clin Microbiol 48:3666-74. 2010
    ..Finally, the CL biotype reservoir in Mexico is unprecedented and must have contributed to the changing epidemiology of global cholera in ways that need to be understood...
  12. pmc Seasonal cholera caused by Vibrio cholerae serogroups O1 and O139 in the coastal aquatic environment of Bangladesh
    Munirul Alam
    International Center for Diarrhoeal Disease Research, Dhaka, Bangladesh
    Appl Environ Microbiol 72:4096-104. 2006
    ..cholerae O139 have been demonstrated. Based on the results of this study, the coastal ecosystem of the Bay of Bengal is concluded to be a significant reservoir for the epidemic serogroups of V. cholerae...
  13. pmc Toxigenic Vibrio cholerae in the aquatic environment of Mathbaria, Bangladesh
    Munirul Alam
    International Center for Diarrhoeal Disease Research Bangladesh, Dhaka, Bangladesh
    Appl Environ Microbiol 72:2849-55. 2006
    ..The biofilm community is concluded to be an additional reservoir of cholera bacteria in the aquatic environment between seasonal epidemics of cholera in Bangladesh...
  14. ncbi request reprint Genetic characteristics of Matlab variants of Vibrio cholerae O1 that are hybrids between classical and El Tor biotypes
    Ashrafus Safa
    Laboratory Sciences Division, Enteric Microbiology Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh ICDDR, B, Centre for Health and Population Research, GPO Box 128, Dhaka 1000, Bangladesh
    J Med Microbiol 55:1563-9. 2006
    ..The genetic relatedness of Matlab variants to the V. cholerae strains recently isolated in Mozambique is another important observation of this study, which underscores the epidemiological significance of Matlab variants...
  15. doi request reprint Changing genotypes of cholera toxin (CT) of Vibrio cholerae O139 in Bangladesh and description of three new CT genotypes
    Nurul A Bhuiyan
    International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    FEMS Immunol Med Microbiol 57:136-41. 2009
    ..This change and the impact that it causes to the epidemiology of cholera caused by O139 should be closely monitored...
  16. pmc Transmission of Infectious Vibrio cholerae through Drinking Water among the Household Contacts of Cholera Patients (CHoBI7 Trial)
    Raisa Rafique
    International Center for Diarrhoeal Disease Research Bangladesh, Dhaka, Bangladesh
    Front Microbiol 7:1635. 2016
    ..cholerae within the household contacts of cholera patients through drinking water underscores the need for safe water to prevent spread of cholera and related deaths in Dhaka city...
  17. pmc Chlorination of Household Drinking Water Among Cholera Patients' Households to Prevent Transmission of Toxigenic Vibrio cholerae in Dhaka, Bangladesh: CHoBI7 Trial
    Mahamud Ur Rashid
    International Centre for Diarrheal Disease Research, Bangladesh ICDDR, B, Dhaka, Bangladesh
    Am J Trop Med Hyg 95:1299-1304. 2016
    ..cholerae...
  18. doi request reprint Rapid dipstick detection of Vibrio cholerae in household stored and municipal water in Dhaka, Bangladesh: CHoBI7 trial
    Mahamud Ur Rashid
    ICDDR, B, Dhaka, Bangladesh
    Trop Med Int Health . 2016
    ..The Crystal VC® dipstick test is a rapid method for detecting V. cholerae in stool and water. However, to date no study has investigated the use of the rapid dipstick test for household surveillance of stored drinking water...
  19. pmc Observed Handwashing with Soap Practices Among Cholera Patients and Accompanying Household Members in a Hospital Setting (CHoBI7 Trial)
    Fatema Zohura
    International Centre for Diarrhoeal Disease Research, Bangladesh ICDDR, B, Dhaka, Bangladesh
    Am J Trop Med Hyg 95:1314-1318. 2016
    ..Observed handwashing with soap at key times among patients and accompanying household members was very low. These findings highlight the urgent need for interventions to target this high-risk population...
  20. pmc Metagenomic profile of gut microbiota in children during cholera and recovery
    Shirajum Monira
    International Center for Diarrhoeal Disease Research, Bangladesh
    Gut Pathog 5:1. 2013
    ..The diverse bacterial communities colonizing the gut (gastrointestinal tract) of infants as commensal flora, which play an important role in nutrient absorption and determining the state of health, are known to alter due to diarrhea...
  21. pmc Phenotypic, genotypic, and antibiotic sensitivity patterns of strains isolated from the cholera epidemic in Zimbabwe
    Mohammad S Islam
    International Centre for Diarrhoeal Disease Research, Bangladesh, 68 Shahid Tajuddin Ahmed, Sarani, Mohakhali, Dhaka 1212, Bangladesh
    J Clin Microbiol 49:2325-7. 2011
    ..All of the strains were susceptible to tetracycline, doxycycline, ciprofloxacin, and azithromycin by disc diffusion, but susceptibility to tetracycline and azithromycin diminished when observed using the MIC method...
  22. pmc Occurrence of Hybrid Escherichia coli Strains Carrying Shiga Toxin and Heat-Stable Toxin in Livestock of Bangladesh
    Fatema Tuz Johura
    International Center for Diarrheal Disease Research, Bangladesh ICDDR, B, Dhaka, Bangladesh
    Front Public Health 4:287. 2016
    ..Multidrug-resistant E. coli STEC-ETEC hybrid strains in domesticated animals pose a public health threat for humans in Bangladesh...
  23. pmc 16S rRNA gene-targeted TTGE in determining diversity of gut microbiota during acute diarrhoea and convalescence
    Shirajum Monira
    ICDDR, B, GPO Box 128, Dhaka 1000, Bangladesh
    J Health Popul Nutr 30:250-6. 2012
    ..9, p<0.01). These results suggest that appropriate therapeutic and post-diarrhoeal nutritional intervention might be beneficial for the early microbial restoration and recovery...
  24. ncbi request reprint Antibacterial activity of Psidium guajava leaf and bark against multidrug-resistant Vibrio cholerae: implication for cholera control
    Niaz Rahim
    International Center for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    Jpn J Infect Dis 63:271-4. 2010
    ..extract/vol. ORS). P. guajava, which is widely distributed in Bangladesh, thus offers great potential for use in indigenous, herbal medicine for controlling epidemics of cholera...
  25. doi request reprint Major tdh(+)Vibrio parahaemolyticus serotype changes temporally in the Bay of Bengal estuary of Bangladesh
    Farhana Akther
    Infectious Diseases Division, International Center for Diarrheal Disease Research, Bangladesh ICDDR, B, Dhaka 1212, Bangladesh
    Infect Genet Evol 41:153-9. 2016
    ..parahaemolyticus infection in Bangladesh. ..
  26. pmc Effect of transport at ambient temperature on detection and isolation of Vibrio cholerae from environmental samples
    Munirul Alam
    International Center for Diarrhoeal Disease Research, Dhaka, Bangladesh
    Appl Environ Microbiol 72:2185-90. 2006
    ..cholerae from freshwater ecosystems can be achieved by holding samples at the ambient temperature, an observation that has significant implications for tracking this pathogen in diverse aquatic environments...
  27. pmc Occurrence in Mexico, 1998-2008, of Vibrio cholerae CTX+ El Tor carrying an additional truncated CTX prophage
    Munirul Alam
    International Center for Diarrheal Disease Research, Bangladesh ICDDR, B, Mohakhali, Dhaka 1212, Bangladesh
    Proc Natl Acad Sci U S A 111:9917-22. 2014
    ..cholerae ET N16961 and V. cholerae ET isolated in Peru. ..
  28. pmc Promotion of Cholera Awareness Among Households of Cholera Patients: A Randomized Controlled Trial of the Cholera-Hospital-Based-Intervention-for-7 Days (CHoBI7) Intervention
    K M Saif-Ur-Rahman
    International Centre for Diarrhoeal Disease Research, Bangladesh ICDDR, B, Dhaka, Bangladesh
    Am J Trop Med Hyg 95:1292-1298. 2016
    ..These findings suggest that the CHoBI7 intervention presents a promising approach to increase cholera awareness among this high-risk population...
  29. pmc Comparison of inferred relatedness based on multilocus variable-number tandem-repeat analysis and whole genome sequencing of Vibrio cholerae O1
    Mahamud Ur Rashid
    School of Medicine, University of Maryland, Baltimore, MD 21201, USA Department of Microbiology, International Centre for Diarrheal Disease Research, Mohakhali, 1212 Dhaka, Bangladesh
    FEMS Microbiol Lett 363:. 2016
    ....
  30. pmc Role of Shrimp Chitin in the Ecology of Toxigenic Vibrio cholerae and Cholera Transmission
    Shamsun Nahar
    Laboratory Sciences Division, Enteric and food Microbiology, International Center for Diarrheal Disease Research Dhaka, Bangladesh
    Front Microbiol 2:260. 2011
    ..It is concluded that the abundance of chitin that occurs during blooms plays an important role in the aquatic life cycle of V. cholerae and, ultimately, in the seasonal transmission of cholera...
  31. pmc Sustained Uptake of a Hospital-Based Handwashing with Soap and Water Treatment Intervention (Cholera-Hospital-Based Intervention for 7 Days [CHoBI7]): A Randomized Controlled Trial
    Christine Marie George
    Johns Hopkins University, Baltimore, Maryland International Centre for Diarrhoeal Disease Research Bangladesh icddr, B, Dhaka, Bangladesh
    Am J Trop Med Hyg 94:428-36. 2016
    ..These findings demonstrate that the hospital-based CHoBI7 intervention can lead to significant increases in handwashing with soap practices and improved stored drinking water quality 6 to 12 months post-intervention. ..
  32. pmc Genomic relatedness of the new Matlab variants of Vibrio cholerae O1 to the classical and El Tor biotypes as determined by pulsed-field gel electrophoresis
    Ashrafus Safa
    Laboratory Sciences Division, ICDDR B, GPO Box 128, Dhaka 1000, Bangladesh
    J Clin Microbiol 43:1401-4. 2005
    ..Strains that clustered with the classical biotype appear to have been derived from the classical strains, which are thought to be extinct...
  33. pmc Seasonal cholera from multiple small outbreaks, rural Bangladesh
    O Colin Stine
    University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Emerg Infect Dis 14:831-3. 2008
    ..The observed minimal overlap in VNTR patterns between the 2 communities was consistent with sequential, small outbreaks from local sources...
  34. pmc Occurrence and expression of luminescence in Vibrio cholerae
    Christopher J Grim
    University of Maryland Institute for Advanced Computer Studies, University of Maryland, College Park, Maryland, USA
    Appl Environ Microbiol 74:708-15. 2008
    ..Luminescence expression patterns of V. cholerae were also investigated, and isolates could be grouped based on expression level. Several strains with defective expression of the lux operon, including natural K variants, were identified...
  35. ncbi request reprint Application of duplex-PCR in rapid and reliable detection of toxigenic Vibrio cholerae in water samples in Thailand
    Chariya Chomvarin
    Department of Microbiology, Faculty of Medicine, Khon Kaen University, Thailand
    J Gen Appl Microbiol 53:229-37. 2007
    ..cholerae in the water sample was detected in duplex PCR. Pre-PCR filtration followed by enrichment for 3 h significantly increase in the efficiency of duplex-PCR detection of toxigenic V. cholerae...