Michael R Reithofer

Summary

Affiliation: University of Vienna
Country: Austria

Publications

  1. doi request reprint Novel bis(carboxylato)dichlorido(ethane-1,2-diamine)platinum(IV) complexes with exceptionally high cytotoxicity
    Michael R Reithofer
    University of Vienna, Institute of Inorganic Chemistry, Waehringer Strasse 42, A 1090 Vienna, Austria
    J Inorg Biochem 102:2072-7. 2008
  2. doi request reprint Novel endothall-containing platinum(IV) complexes: synthesis, characterization, and cytotoxic activity
    Michael R Reithofer
    University of Vienna, Institute of Inorganic Chemistry, Wahringer Strasse 42, A 1090 Vienna
    Chem Biodivers 5:2160-70. 2008
  3. doi request reprint Tuning of lipophilicity and cytotoxic potency by structural variation of anticancer platinum(IV) complexes
    Michael R Reithofer
    University of Vienna, Institute of Inorganic Chemistry, Waehringer Str 42, A 1090 Vienna, Austria
    J Inorg Biochem 105:46-51. 2011
  4. ncbi request reprint Novel di- and tetracarboxylatoplatinum(IV) complexes. Synthesis, characterization, cytotoxic activity, and DNA platination
    Michael R Reithofer
    Institute of Inorganic Chemistry, University of Vienna, Austria
    J Med Chem 50:6692-9. 2007
  5. pmc The first example of MEEKC-ICP-MS coupling and its application for the analysis of anticancer platinum complexes
    Anna K Bytzek
    Institute of Inorganic Chemistry, University of Vienna, Vienna, Austria
    Electrophoresis 31:1144-50. 2010

Detail Information

Publications5

  1. doi request reprint Novel bis(carboxylato)dichlorido(ethane-1,2-diamine)platinum(IV) complexes with exceptionally high cytotoxicity
    Michael R Reithofer
    University of Vienna, Institute of Inorganic Chemistry, Waehringer Strasse 42, A 1090 Vienna, Austria
    J Inorg Biochem 102:2072-7. 2008
    ..Structure-activity relationships showed that the cytotoxicity increased with increasing lipophilicity of the alcoholate moiety yielding IC50 values in the low micromolar or even low nanomolar range...
  2. doi request reprint Novel endothall-containing platinum(IV) complexes: synthesis, characterization, and cytotoxic activity
    Michael R Reithofer
    University of Vienna, Institute of Inorganic Chemistry, Wahringer Strasse 42, A 1090 Vienna
    Chem Biodivers 5:2160-70. 2008
    ....
  3. doi request reprint Tuning of lipophilicity and cytotoxic potency by structural variation of anticancer platinum(IV) complexes
    Michael R Reithofer
    University of Vienna, Institute of Inorganic Chemistry, Waehringer Str 42, A 1090 Vienna, Austria
    J Inorg Biochem 105:46-51. 2011
    ..Only minor effects for complexes featuring polar end groups were detected...
  4. ncbi request reprint Novel di- and tetracarboxylatoplatinum(IV) complexes. Synthesis, characterization, cytotoxic activity, and DNA platination
    Michael R Reithofer
    Institute of Inorganic Chemistry, University of Vienna, Austria
    J Med Chem 50:6692-9. 2007
    ..DNA platination studies of selected complexes revealed a high DNA platination capacity in parallel to a high cytotoxic potential and vice versa...
  5. pmc The first example of MEEKC-ICP-MS coupling and its application for the analysis of anticancer platinum complexes
    Anna K Bytzek
    Institute of Inorganic Chemistry, University of Vienna, Vienna, Austria
    Electrophoresis 31:1144-50. 2010
    ..The migration behavior of the Pt(II) and Pt(IV) compounds under investigation is correlated to their different chemical structures...