Affiliation: University of Vienna
- NGC: lossless and lossy compression of aligned high-throughput sequencing dataNiko Popitsch
Center for Integrative Bioinformatics Vienna, Max F Perutz Laboratories, University of Vienna, Medical University of Vienna, Dr Bohr Gasse 9, Vienna A 1030, Austria
Nucleic Acids Res 41:e27. 2013..By applying two popular variant and genotype prediction tools to the decompressed data, we could show that the lossy compression modes preserve >99% of all called variants while outperforming comparable methods in some configurations...