Harald Noedl

Summary

Affiliation: University of Vienna
Country: Austria

Publications

  1. pmc Simple histidine-rich protein 2 double-site sandwich enzyme-linked immunosorbent assay for use in malaria drug sensitivity testing
    Harald Noedl
    Department of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Kinderspitalgasse 15, A 1095 Vienna, Austria
    Antimicrob Agents Chemother 49:3575-7. 2005
  2. ncbi request reprint Malaria drug-susceptibility testing. HRP2-based assays: current data, future perspectives
    Harald Noedl
    Department of Specific Prophylaxis and Tropical Medicine, Institute of Pathophysiology, University of Vienna, Vienna, Austria
    Wien Klin Wochenschr 115:23-7. 2003
  3. pmc Nonisotopic, semiautomated plasmodium falciparum bioassay for measurement of antimalarial drug levels in serum or plasma
    Harald Noedl
    Department of Specific Prophylaxis and Tropical Medicine, Institute of Pathophysiology, University of Vienna, Kinderspitalgasse 15, A 1095 Vienna, Austria
    Antimicrob Agents Chemother 48:4485-7. 2004
  4. ncbi request reprint Plasmodium falciparum: effect of anti-malarial drugs on the production and secretion characteristics of histidine-rich protein II
    Harald Noedl
    Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences USAMC AFRIMS, Bangkok Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Exp Parasitol 102:157-63. 2002
  5. ncbi request reprint Malaria drug-sensitivity testing: new assays, new perspectives
    Harald Noedl
    Dept of Specific Prophylaxis and Tropical Medicine, Institute of Pathophysiology, University of Vienna, Kinderspitalgasse 15, A 1095, Vienna, Austria
    Trends Parasitol 19:175-81. 2003
  6. ncbi request reprint Predictive role of laboratory and clinical treatment response parameters and glucose-6-phosphate dehydrogenase status in the therapy of falciparum malaria
    Harald Noedl
    Department of Specific Prophylaxis and Tropical Medicine, Institute of Pathophysiology, University of Vienna, Austria
    Wien Klin Wochenschr 114:158-63. 2002
  7. pmc Histidine-rich protein II: a novel approach to malaria drug sensitivity testing
    Harald Noedl
    Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences USAMC AFRIMS, Bangkok, Thailand
    Antimicrob Agents Chemother 46:1658-64. 2002
  8. ncbi request reprint A histidine-rich protein 2-based malaria drug sensitivity assay for field use
    Harald Noedl
    Department of Immunology and Medicine, United States Army Medical Component, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Am J Trop Med Hyg 71:711-4. 2004
  9. pmc In vitro antimalarial activity of azithromycin, artesunate, and quinine in combination and correlation with clinical outcome
    Harald Noedl
    Department of Specific Prophylaxis and Tropical Medicine, Center for Physiology and Pathophysiology, Medical University of Vienna, Austria, and Hospital for Tropical Diseases, Bangkok, Thailand
    Antimicrob Agents Chemother 51:651-6. 2007
  10. ncbi request reprint [In vitro interaction studies of azithromycin and dihydroartemisinin in Plasmodium falciparum isolates from Bangladesh]
    Matthias G Vossen
    Department of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Austria
    Wien Klin Wochenschr 119:71-5. 2007

Detail Information

Publications52

  1. pmc Simple histidine-rich protein 2 double-site sandwich enzyme-linked immunosorbent assay for use in malaria drug sensitivity testing
    Harald Noedl
    Department of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Kinderspitalgasse 15, A 1095 Vienna, Austria
    Antimicrob Agents Chemother 49:3575-7. 2005
    ..The sensitivity is comparable and the drug sensitivity results very closely match those obtained with the commercial ELISA kits (R(2) = 0.979; P < 0.001; mean log difference at the 50% inhibitory concentration = 0.07)...
  2. ncbi request reprint Malaria drug-susceptibility testing. HRP2-based assays: current data, future perspectives
    Harald Noedl
    Department of Specific Prophylaxis and Tropical Medicine, Institute of Pathophysiology, University of Vienna, Vienna, Austria
    Wien Klin Wochenschr 115:23-7. 2003
    ..It has proved to be a valuable tool for a wide range of applications, from epidemiological field studies to the screening of new drugs, and may therefore have the potential to replace traditional in-vitro drug-sensitivity techniques...
  3. pmc Nonisotopic, semiautomated plasmodium falciparum bioassay for measurement of antimalarial drug levels in serum or plasma
    Harald Noedl
    Department of Specific Prophylaxis and Tropical Medicine, Institute of Pathophysiology, University of Vienna, Kinderspitalgasse 15, A 1095 Vienna, Austria
    Antimicrob Agents Chemother 48:4485-7. 2004
    ..The results closely paralleled those obtained with isotopic bioassays (R = 0.988, P < 0.001) and high-performance liquid chromatography-electrochemical detection (R = 0.978, P < 0.001)...
  4. ncbi request reprint Plasmodium falciparum: effect of anti-malarial drugs on the production and secretion characteristics of histidine-rich protein II
    Harald Noedl
    Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences USAMC AFRIMS, Bangkok Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Exp Parasitol 102:157-63. 2002
    ..HRP2 therefore allows for a very accurate estimation of parasite development and its inhibition and may therefore be ideally suited for use in drug sensitivity or bioassays...
  5. ncbi request reprint Malaria drug-sensitivity testing: new assays, new perspectives
    Harald Noedl
    Dept of Specific Prophylaxis and Tropical Medicine, Institute of Pathophysiology, University of Vienna, Kinderspitalgasse 15, A 1095, Vienna, Austria
    Trends Parasitol 19:175-81. 2003
    ..This review examines the various new approaches to the in vitro assessment of malaria drug sensitivity and their limitations...
  6. ncbi request reprint Predictive role of laboratory and clinical treatment response parameters and glucose-6-phosphate dehydrogenase status in the therapy of falciparum malaria
    Harald Noedl
    Department of Specific Prophylaxis and Tropical Medicine, Institute of Pathophysiology, University of Vienna, Austria
    Wien Klin Wochenschr 114:158-63. 2002
    ..Several parasitological and haematological parameters, such as G6PD level and parasitaemia, were identified as reliable predictors of the expected duration of clinical disease in malaria...
  7. pmc Histidine-rich protein II: a novel approach to malaria drug sensitivity testing
    Harald Noedl
    Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences USAMC AFRIMS, Bangkok, Thailand
    Antimicrob Agents Chemother 46:1658-64. 2002
    ..Standard operating procedures, updated information, and analytical software are available from http://malaria.farch.net...
  8. ncbi request reprint A histidine-rich protein 2-based malaria drug sensitivity assay for field use
    Harald Noedl
    Department of Immunology and Medicine, United States Army Medical Component, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Am J Trop Med Hyg 71:711-4. 2004
    ..43, 61.89, 326.75, and 185.31 nM, respectively). Results very closely matched those obtained with a modified World Health Organization schizont maturation assay (R2 = 0.96, P < 0.001; mean log difference at IC50 = 0.054)...
  9. pmc In vitro antimalarial activity of azithromycin, artesunate, and quinine in combination and correlation with clinical outcome
    Harald Noedl
    Department of Specific Prophylaxis and Tropical Medicine, Center for Physiology and Pathophysiology, Medical University of Vienna, Austria, and Hospital for Tropical Diseases, Bangkok, Thailand
    Antimicrob Agents Chemother 51:651-6. 2007
    ....
  10. ncbi request reprint [In vitro interaction studies of azithromycin and dihydroartemisinin in Plasmodium falciparum isolates from Bangladesh]
    Matthias G Vossen
    Department of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Austria
    Wien Klin Wochenschr 119:71-5. 2007
    ..A trend towards lower SFICs was observed with rising inhibitory concentrations (i.e. at IC90 and IC95). Correlation analysis suggests a different mode of action for azithromycin as compared to traditional antimalarials...
  11. doi request reprint Azithromycin combination therapy for the treatment of uncomplicated falciparum malaria in Bangladesh: an open-label randomized, controlled clinical trial
    Kamala Thriemer
    Department of Specific Prophylaxes and Tropical Medicine, Medical University of Vienna, Austria
    J Infect Dis 202:392-8. 2010
    ..In recent studies, the combination of azithromycin and artesunate has proven to be a promising alternative for the treatment of uncomplicated falciparum malaria...
  12. ncbi request reprint In vitro interaction of dihydroartemisin and lumefantrine in clinical field isolates from Bangladesh
    Kamala Thriemer
    Department of Specific Prophylaxis and Tropical Medicine, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria
    Wien Klin Wochenschr 119:67-70. 2007
    ..Although activity correlations between DHA and lumefantrine were significant, indicating possible cross sensitivity patterns, our data confirm that artemether-lumefantrine is a highly synergistic drug combination...
  13. doi request reprint High prevalence and genetic diversity of Plasmodium malariae and no evidence of Plasmodium knowlesi in Bangladesh
    Hans Peter Fuehrer
    Institute of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Kinderspitalgasse 15, 1090, Vienna, Austria
    Parasitol Res 113:1537-43. 2014
    ..knowlesi was found. We conclude that the role of P. malariae is highly underestimated in rural Bangladesh with major implications for malaria control and elimination strategies...
  14. pmc Optimizing the HRP-2 in vitro malaria drug susceptibility assay using a reference clone to improve comparisons of Plasmodium falciparum field isolates
    Wiriya Rutvisuttinunt
    Department of Immunology and Medicine, US Army Medical Corps, Armed Forces Research Institute of Medical Sciences USAMC AFRIMS, Bangkok, Thailand
    Malar J 11:325. 2012
    ..Although in vitro anti-malarial susceptibility tests are widely used, uncertainties remain regarding interpretation of P. falciparum field isolate values...
  15. pmc Ex vivo drug sensitivity profiles of Plasmodium falciparum field isolates from Cambodia and Thailand, 2005 to 2010, determined by a histidine-rich protein-2 assay
    Stuart D Tyner
    Department of Immunology and Medicine, US Army Medical Corps, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Malar J 11:198. 2012
    ....
  16. ncbi request reprint Drug sensitivity of Plasmodium falciparum along the Thai-Myanmar border using the new field-deployable HRP2 in vitro assay
    Bernhard Attlmayr
    Department of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Vienna, Austria
    Wien Klin Wochenschr 117:35-8. 2005
    ..The HRP2 field test was found to be highly sensitive and simple enough to be entirely performed in the field...
  17. doi request reprint Artemisinin resistance in Cambodia: a clinical trial designed to address an emerging problem in Southeast Asia
    Harald Noedl
    Institute of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Vienna, Austria
    Clin Infect Dis 51:e82-9. 2010
    ..This article provides additional data from a clinical trial that has been published in The New England Journal of Medicine...
  18. ncbi request reprint Sensitivity and specificity of an antigen detection ELISA for malaria diagnosis
    Harald Noedl
    Department of Immunology and Medicine, USAMC AFRIMS, Bangkok, Thailand
    Am J Trop Med Hyg 75:1205-8. 2006
    ..We conclude that ELISA serves as an excellent tool to augment microscopy as the gold standard for P. falciparum diagnosis in research settings and should be further evaluated for screening in blood banks...
  19. ncbi request reprint [In vitro antimalarial drug resistance in Southeastern Bangladesh]
    Bernhard Attlmayr
    Department of Specific Prophylaxis and Tropical Medicine, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria
    Wien Klin Wochenschr 118:58-61. 2006
    ..48 microM, 95% CI: 120.78-249.17) and pyrimethamine (IC50 = 1.7 microM, 95% CI: 1.25-2.3; IC90 = 4.83 microM, 95% CI: 3.17-7.37) with quinine proved to be an interesting option for treating uncomplicated falciparum malaria in Bangladesh...
  20. pmc Evidence of a major reservoir of non-malarial febrile diseases in malaria-endemic regions of Bangladesh
    Paul Swoboda
    Institute of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Vienna, Austria MARIB, Malaria Research Initiative Bandarban, Bandarban, Bangladesh Institute of Parasitology, Department of Pathobiology, University of Veterinary Medicine Vienna ICDDR, B, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    Am J Trop Med Hyg 90:377-82. 2014
    ..In an area with point prevalences of more than 40% for malaria among fever cases, even higher seroprevalence rates of leptospirosis and typhoid fever provide evidence of a major persistent reservoir of these pathogens...
  21. doi request reprint Endoparasites of rodents from the Chittagong Hill Tracts in Southeastern Bangladesh
    Hans Peter Fuehrer
    Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria
    Wien Klin Wochenschr 124:27-30. 2012
    ..n = 2) and Trichuris sp. (n = 1)-and acanthocephalans (Moniliformis moniliformis; n = 2). Several of the examined parasites are of zoonotic importance via direct or indirect transmission (e.g. C. hepatica) and may affect humans...
  22. pmc Current status of artemisinin-resistant falciparum malaria in South Asia: a randomized controlled artesunate monotherapy trial in Bangladesh
    Peter Starzengruber
    Institute of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Vienna, Austria
    PLoS ONE 7:e52236. 2012
    ..The main objective of this trial was to track the potential emergence of artemisinin resistance in Bangladesh, which in terms of drug resistance forms a gateway to the Indian subcontinent...
  23. pmc Pharmacokinetics and pharmacodynamics of oral artesunate monotherapy in patients with uncomplicated Plasmodium falciparum malaria in western Cambodia
    David Saunders
    Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences AFRIMS, Bangkok, Thailand
    Antimicrob Agents Chemother 56:5484-93. 2012
    ..While direct concentration-effect relationships were not found, it remains possible that a population PK modeling approach that allows modeling of greater dose separation might discern more-subtle relationships...
  24. doi request reprint Plasmodium ovale in Bangladesh: genetic diversity and the first known evidence of the sympatric distribution of Plasmodium ovale curtisi and Plasmodium ovale wallikeri in southern Asia
    Hans Peter Fuehrer
    Institute of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Kinderspitalgasse 15, 1090 Vienna, Austria
    Int J Parasitol 42:693-9. 2012
    ..High rates of mixed infections, the emergence of "new" human malaria parasite species and the evidence of zoonotic capability call for optimised diagnostic strategies for a new era of eradication...
  25. doi request reprint Antiplasmodial activity of flavonol quercetin and its analogues in Plasmodium falciparum: evidence from clinical isolates in Bangladesh and standardized parasite clones
    Deepa Ganesh
    Institute of Medical Chemistry, Department of Biochemistry and Genetics, Medical University of Vienna, Waehringer Strasse 10, Vienna, 1090, Austria
    Parasitol Res 110:2289-95. 2012
    ..Thus, our results provide important evidence of the antimalarial activity of flavonoids in traditional use and thus warrant further investigation of these compounds as potential antiplasmodial agents...
  26. ncbi request reprint Synergistic interaction between monodesbutyl-benflumetol and retinol in Plasmodium falciparum
    Maria Parizek
    Institute of Specific Prophylaxis and Tropical Medicine, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria
    Wien Klin Wochenschr 119:53-9. 2007
    ..00 nM and 13.74 nM, respectively, indicating significant synergistic interaction between DBB and retinol. The degree of synergism increases with the retinol concentration in the combination and is highest at the EC(99) level for DBB...
  27. ncbi request reprint Azithromycin combination therapy with artesunate or quinine for the treatment of uncomplicated Plasmodium falciparum malaria in adults: a randomized, phase 2 clinical trial in Thailand
    Harald Noedl
    1Department of Immunology and Medicine, USAMC AFRIMS, Bangkok, Thailand
    Clin Infect Dis 43:1264-71. 2006
    ..Azithromycin is a macrolide antibiotic that is particularly attractive as an antimalarial because of its safety in children and the extensive experience with its use during pregnancy...
  28. pmc Mirincamycin, an old candidate for malaria combination treatment and prophylaxis in the 21st century: in vitro interaction profiles with potential partner drugs in continuous culture and field isolates
    Peter Starzengruber
    Institute of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Vienna, Austria
    Malar J 13:228. 2014
    ..Spreading resistance of Plasmodium falciparum to existing drugs calls for the search for novel anti-malarial drugs and combinations for the treatment of falciparum malaria...
  29. pmc High prevalence of asymptomatic malaria in south-eastern Bangladesh
    Peter Starzengruber
    Institute of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Kinderspitalgasse 15, Vienna 1090, Austria
    Malar J 13:16. 2014
    ..surveillance and epidemiological data on malaria from the CHT are limited; existing data report Plasmodium falciparum and Plasmodium vivax as the dominant species...
  30. doi request reprint Indigenous Dirofilaria immitis in Bangladesh
    Hans Peter Fuehrer
    Department of Pathobiology, Institute of Parasitology, University of Veterinary Medicine, Veterinarplatz 1, 1210, Vienna, Austria
    Parasitol Res 112:2393-5. 2013
    ..immitis via nocturnal mosquito vectors, which may lead to high prevalences of this pathogen in the canine population and thus increase the risk of human infections with this neglected parasitic disease...
  31. ncbi request reprint The need for new antimalarial drugs less prone to resistance
    Harald Noedl
    Institute of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Vienna, Austria
    Curr Pharm Des 19:266-9. 2013
    ....
  32. pmc Two techniques for simultaneous identification of Plasmodium ovale curtisi and Plasmodium ovale wallikeri by use of the small-subunit rRNA gene
    Hans Peter Fuehrer
    Institute of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Vienna, Austria
    J Clin Microbiol 50:4100-2. 2012
    ..We describe a simple, cost- and time-efficient multiplex nested PCR and a nested PCR using a novel set of primers for the simultaneous detection of P. ovale curtisi and P. ovale wallikeri...
  33. pmc Plasmodium falciparum gametocyte carriage is associated with subsequent Plasmodium vivax relapse after treatment
    Jessica T Lin
    Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    PLoS ONE 6:e18716. 2011
    ..vivax coinfection and subsequent relapse. These patients may benefit from empiric treatment with an 8-aminoquinolone such as primaquine...
  34. pmc Indigenous Plasmodium ovale malaria in Bangladesh
    Hans Peter Fuehrer
    Department of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Vienna, Austria
    Am J Trop Med Hyg 83:75-8. 2010
    ..3% (61.3-74.5%), followed by P. vivax (15.3%; 10.9-21.2%), P. malariae (1.6%; 0.5-4.6%), P. ovale (1.6%; 0.5-4.6%), and mixed infections (13.2%; 9.1-18.8%). We found no evidence of P. knowlesi in this region...
  35. pmc The SYBR Green I malaria drug sensitivity assay: performance in low parasitemia samples
    Matthias G Vossen
    Institute of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Kinderspitalgasse 15, A 1090 Vienna, Austria
    Am J Trop Med Hyg 82:398-401. 2010
    ..However, because of its lack of sensitivity in whole blood samples its usefulness for testing clinical samples may be limited...
  36. ncbi request reprint In vitro activity of tafenoquine alone and in combination with artemisinin against Plasmodium falciparum
    Michael Ramharter
    Department of Specific Prophylaxis and Tropical Medicine, Institute of Pathophysiology, University of Vienna, Austria
    Am J Trop Med Hyg 67:39-43. 2002
    ..9 nmol/L and 84.3 nmol/L. The combination was synergistic. Tafenoquine appears to be a promising candidate for treating multidrug-resistant falciparum malaria, especially in combination with artemisinin derivatives...
  37. ncbi request reprint Characterization of a novel class of antimalarials and its applicability to plasmodial target identification
    Oumaporn Tasanor
    Institute of Medical Chemistry, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria
    Wien Klin Wochenschr 119:83-7. 2007
    ..falciparum. The lead compound propafenone is a registered drug and this compound class might therefore have a major potential as an antimalarial drug, either alone, or in combination with conventional antimalarials...
  38. pmc Novel nested direct PCR technique for malaria diagnosis using filter paper samples
    Hans Peter Fuehrer
    Department of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Kinderspitalgasse 15, A 1090 Vienna, Austria
    J Clin Microbiol 49:1628-30. 2011
    ..Direct PCR provides a rapid, highly sensitive, and cost-effective alternative to diagnosing malaria using filter paper samples and standard nested PCR...
  39. ncbi request reprint Molecular markers for drug resistance in malaria: use in treatment, diagnosis and epidemiology
    Walther Helmut Wernsdorfer
    Department of Specific Prophylaxis and Tropical Medicine, Institute of Pathophysiology, University of Vienna, Austria
    Curr Opin Infect Dis 16:553-8. 2003
    ..The identification and implications of molecular markers for antimalarial drug resistance - the subject of this review - are key issues in elucidating and eventually controlling resistance...
  40. ncbi request reprint Unexpected frequency, duration and spectrum of adverse events after therapeutic dose of mefloquine in healthy adults
    Pamela Rendi-Wagner
    Department of Specific Prophylaxis and Tropical Medicine, Institute of Pathophysiology, University of Vienna, Kinderspitalgasse 15, A 1095 Vienna, Austria
    Acta Trop 81:167-73. 2002
    ....
  41. ncbi request reprint An in vitro system for assessing the sensitivity of Plasmodium vivax to chloroquine
    Oumaporn Tasanor
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Acta Trop 83:49-61. 2002
    ..3 nM, as compared to 49.7 nM with 42 h of incubation. The geometric mean cut-off concentration of parasite development was 488 nM with 30 h of incubation as against 470 nM with 42 h of incubation...
  42. ncbi request reprint Apparent relapse of imported Plasmodium ovale malaria in a pregnant woman
    Rodney L Coldren
    Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Am J Trop Med Hyg 77:992-4. 2007
    ..She delivered a healthy term infant and received radical cure with primaquine after cessation of breastfeeding. This case shows challenging issues in detection and management of imported P. ovale malaria...
  43. ncbi request reprint Ectoparasites of livestock, dogs, and wild rodents in the Chittagong Hill Tracts in southeastern Bangladesh
    Hans Peter Fuehrer
    Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria
    Parasitol Res 111:1867-70. 2012
    ..Several zoonotic diseases can be transmitted by ectoparasites in this area, where the majority of the population live in basic housing conditions and in direct contact with livestock, dogs, and rodents...
  44. doi request reprint ABC - antibiotics-based combinations for the treatment of severe malaria?
    Harald Noedl
    Medical University of Vienna, Kinderspitalgasse 15, A 1090 Vienna, Austria
    Trends Parasitol 25:540-4. 2009
    ....
  45. pmc Performance of BinaxNOW G6PD deficiency point-of-care diagnostic in P. vivax-infected subjects
    Lyda Osorio
    Epidemiology and Population Health Research Group GESP, School of Public Health, Universidad del Valle, Cali, Colombia Clinical Research and Development Fellowship, World Health Organization Special Program for Research and Training in Tropical Diseases WHO TDR at GlaxoSmithKline GSK, Uxbridge, Middlesex, United Kingdom GlaxoSmithKline Research and Development, Uxbridge, Middlesex, United Kingdom Department of Medicine, Sri Ramchandra Medical College and Research Institute, Porur, Chennai, Tamil Nadu, India Shoklo Malaria Research Unit, Mae Sot, Thailand MV Hospital and Research Centre, Lucknow, Uttar Pradesh, India Institute of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Vienna, Austria Sardar Patel Medical College, Bikaner, Rajasthan, India Department of Medicine, Rajasthan University of Health Sciences Medical College, Jaipur, India Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, Amazonas, Brazil Instituto de Medicina Tropical, Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Chirurgische Klinik Innenstadt
    Am J Trop Med Hyg 92:22-7. 2015
    ..Ensuring safe use of 8-aminoquinolines depends on additional development of simple, highly sensitive G6PD deficiency diagnostic tests suitable for routine use in malaria-endemic areas. ..
  46. pmc Recent advances in detection of Plasmodium ovale: implications of separation into the two species Plasmodium ovale wallikeri and Plasmodium ovale curtisi
    Hans Peter Fuehrer
    Institute of Parasitology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria
    J Clin Microbiol 52:387-91. 2014
    ..ovale wallikeri and P. ovale curtisi as well as tools for the simultaneous detection of P. ovale sp. An update for the widely used NP-1993 to NP-2005 (SSU rRNA) protocols for all human malaria parasites is discussed. ..
  47. doi request reprint Recent Advances in Detection of Plasmodium ovale: Implications of Separation into the Two Species Plasmodium ovale wallikeri and Plasmodium ovale curtisi
    Hans Peter Fuehrer
    Institute of Parasitology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria
    J Clin Microbiol 52:387-91. 2014
    ..ovale wallikeri and P. ovale curtisi as well as tools for the simultaneous detection of P. ovale sp. An update for the widely used NP-1993 to NP-2005 (SSU rRNA) protocols for all human malaria parasites is discussed. ..
  48. ncbi request reprint Evaluation of a new rapid immunochromatographic assay for serodiagnosis of acute hepatitis E infection
    Khin S A Myint
    U S Army Medical Component Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Am J Trop Med Hyg 73:942-6. 2005
    ..5% (95% CI = 97.1-100%) and 95.8% (95% CI = 93.1-97.7%), respectively. These results suggest that this assay is a sensitive and specific tool for the rapid diagnosis of acute HEV infection...
  49. ncbi request reprint Artemisinin resistance: how can we find it?
    Harald Noedl
    Trends Parasitol 21:404-5. 2005
  50. ncbi request reprint Therapeutic efficacy of quinine plus sulfadoxine-pyremethamine for the treatment of uncomplicated falciparum malaria in Bangladesh
    Kamala Thriemer
    International Centre for Diarrhoeal Disease Research, Bangladesh, Bangladesh
    Am J Trop Med Hyg 75:645-9. 2006
    ..These data suggest that the combination of 3 days of quinine with a single dose of sulfadoxine/pyrimethamine is an interesting and affordable alternative as long as or whenever ACT is not available...
  51. ncbi request reprint Improving surveillance for antimalarial drug resistance
    Jean Paul Chretien
    US Department of Defense Global Emerging Infections Surveillance and Response System, Silver Spring, MD 20910, USA
    JAMA 297:2278-81. 2007
  52. ncbi request reprint Therapeutic efficacy of artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Bangladesh
    Rashidul Haque
    Centre for Health and Population Research, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    Am J Trop Med Hyg 76:39-41. 2007
    ..82 +/- 12.14 hours) and parasite (30.36 +/- 19.43 hours) clearance. These data suggest that artemether-lumefantrine is a highly efficacious and well-tolerated treatment for uncomplicated P. falciparum malaria in Bangladesh...