Heinrich Schima

Summary

Affiliation: Medical University of Vienna
Country: Austria

Publications

  1. doi Extended in vivo evaluation of a miniaturized axial flow pump with a novel inflow cannula for a minimal invasive implantation procedure
    Heinrich Schima
    Center for Medical Physics and Biomedical Engineering Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria Ludwig Boltzmann Cluster for Cardiovascular Research, Vienna, Austria Electronic address
    J Heart Lung Transplant 33:422-8. 2014
  2. doi Importance of linguistic details in alarm messages of ventricular assist devices
    Heinrich Schima
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria
    Int J Artif Organs 36:406-9. 2013
  3. ncbi First clinical experience with an automatic control system for rotary blood pumps during ergometry and right-heart catheterization
    Heinrich Schima
    Department of Cardiothoracic Surgery and Ludwig Boltzmann Institute for Cardiosurgical Research, Medical University of Vienna, Vienna, Austria
    J Heart Lung Transplant 25:167-73. 2006
  4. ncbi Development of a reliable automatic speed control system for rotary blood pumps
    Michael Vollkron
    Department of Cardiothoracic Surgery and Ludwig Boltzmann Institute for Cardiosurgical Research, Medical University of Vienna, Vienna, Austria
    J Heart Lung Transplant 24:1878-85. 2005
  5. doi Investigation of hemodynamics in the assisted isolated porcine heart
    Marcus Granegger
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna Austria and Ludwig Boltzmann Cluster for Cardiovascular Research, Vienna Austria
    Int J Artif Organs 36:878-86. 2013
  6. doi Continuous assessment of cardiac function during rotary blood pump support: a contractility index derived from pump flow
    Phornphop Naiyanetr
    Department of Biomedical Engineering and Physics, Medical University of Vienna, Vienna, Austria
    J Heart Lung Transplant 29:37-44. 2010
  7. doi Healing characteristics of electrospun polyurethane grafts with various porosities
    Helga Bergmeister
    Division of Biomedical Research, Medical University Vienna, Vienna, Austria
    Acta Biomater 9:6032-40. 2013
  8. ncbi Advanced suction detection for an axial flow pump
    Michael Vollkron
    Ludwig Boltzmann Institute for Cardiosurgical Research, Medical University of Vienna, Vienna, Austria
    Artif Organs 30:665-70. 2006
  9. doi Renal function and outcome after continuous flow left ventricular assist device implantation
    Sigrid E Sandner
    Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria
    Ann Thorac Surg 87:1072-8. 2009
  10. doi Electrospun small-diameter polyurethane vascular grafts: ingrowth and differentiation of vascular-specific host cells
    Helga Bergmeister
    Division of Biomedical Research, Medical University of Vienna, AKH, Waehringer Guertel 18 20, 1090 Wien, Austria
    Artif Organs 36:54-61. 2012

Collaborators

Detail Information

Publications74

  1. doi Extended in vivo evaluation of a miniaturized axial flow pump with a novel inflow cannula for a minimal invasive implantation procedure
    Heinrich Schima
    Center for Medical Physics and Biomedical Engineering Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria Ludwig Boltzmann Cluster for Cardiovascular Research, Vienna, Austria Electronic address
    J Heart Lung Transplant 33:422-8. 2014
    ..This is particularly challenging for full-flow support. In this study, a minimally invasive implantation technique was developed for a microaxial rotary pump. The system was evaluated in a chronic sheep model...
  2. doi Importance of linguistic details in alarm messages of ventricular assist devices
    Heinrich Schima
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria
    Int J Artif Organs 36:406-9. 2013
    ..It has been proven that displaying messages can significantly improve proper reactions. However, in the case we report, an accidental pump cable disconnection could not be solved without the assistance of the VAD coordinator.
..
  3. ncbi First clinical experience with an automatic control system for rotary blood pumps during ergometry and right-heart catheterization
    Heinrich Schima
    Department of Cardiothoracic Surgery and Ludwig Boltzmann Institute for Cardiosurgical Research, Medical University of Vienna, Vienna, Austria
    J Heart Lung Transplant 25:167-73. 2006
    ..The data provided in this paper, based on hemodynamic and spirometric data during exercise in which a pre-load-sensitive control was used, lend quantitative support to this assumption...
  4. ncbi Development of a reliable automatic speed control system for rotary blood pumps
    Michael Vollkron
    Department of Cardiothoracic Surgery and Ludwig Boltzmann Institute for Cardiosurgical Research, Medical University of Vienna, Vienna, Austria
    J Heart Lung Transplant 24:1878-85. 2005
    ..To provide for these adjustments we developed an algorithm for demand-responsive pump control based on a reliable suction detection system...
  5. doi Investigation of hemodynamics in the assisted isolated porcine heart
    Marcus Granegger
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna Austria and Ludwig Boltzmann Cluster for Cardiovascular Research, Vienna Austria
    Int J Artif Organs 36:878-86. 2013
    ..Isolated and defined changes in hemodynamic parameters are unattainable in animal models, while the heart-pump interaction in its whole complexity cannot be modeled in vitro or in silico...
  6. doi Continuous assessment of cardiac function during rotary blood pump support: a contractility index derived from pump flow
    Phornphop Naiyanetr
    Department of Biomedical Engineering and Physics, Medical University of Vienna, Vienna, Austria
    J Heart Lung Transplant 29:37-44. 2010
    ..This study reports a method to determine contractility that uses readily measured variables of the RBP...
  7. doi Healing characteristics of electrospun polyurethane grafts with various porosities
    Helga Bergmeister
    Division of Biomedical Research, Medical University Vienna, Vienna, Austria
    Acta Biomater 9:6032-40. 2013
    ..Increased porosity improves host cell ingrowth and survival in electrospun conduits. These conduits show successful natural host vessel reconstitution without limitation of biomechanical properties...
  8. ncbi Advanced suction detection for an axial flow pump
    Michael Vollkron
    Ludwig Boltzmann Institute for Cardiosurgical Research, Medical University of Vienna, Vienna, Austria
    Artif Organs 30:665-70. 2006
    ..5%). By application of the clinical experience from the first clinical trial of a physiologic control system it became possible to optimize the sensitivity and specificity of the suction detection system to unprecedented accuracy...
  9. doi Renal function and outcome after continuous flow left ventricular assist device implantation
    Sigrid E Sandner
    Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria
    Ann Thorac Surg 87:1072-8. 2009
    ..Renal dysfunction as a risk factor with the use of left ventricular assist devices (LVAD) is controversial. We determined the effect of renal function on outcomes after continuous flow LVAD implantation...
  10. doi Electrospun small-diameter polyurethane vascular grafts: ingrowth and differentiation of vascular-specific host cells
    Helga Bergmeister
    Division of Biomedical Research, Medical University of Vienna, AKH, Waehringer Guertel 18 20, 1090 Wien, Austria
    Artif Organs 36:54-61. 2012
    ..Besides biomechanical benefits, electrospun polyurethane grafts exhibit excellent biocompatibility in vivo. Cell immigration and differentiation seems to be promoted by the nanostructured artificial matrix...
  11. doi Use of continuous flow ventricular assist devices in patients with heart failure and a normal ejection fraction: a computer-simulation study
    Francesco Moscato
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria
    J Thorac Cardiovasc Surg 145:1352-8. 2013
    ..In the present study, the possible hemodynamic consequences of continuous flow left ventricular assist devices use for these patients were investigated...
  12. doi Development of a pump flow estimator for rotary blood pumps to enhance monitoring of ventricular function
    Marcus Granegger
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringer Guertel 18 20, Vienna, Austria
    Artif Organs 36:691-9. 2012
    ..In conclusion, a flow estimator with sufficient frequency bandwidth and accuracy to allow determination of changes in ventricular contractility even in the case of improving heart function was developed...
  13. doi Age and outcome after continuous-flow left ventricular assist device implantation as bridge to transplantation
    Sigrid E Sandner
    Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria
    J Heart Lung Transplant 28:367-72. 2009
    ..The effect of age on outcomes after continuous-flow left ventricular assist device (LVAD) implantation as a bridge to transplantation (BTT) was determined...
  14. ncbi Development of a suction detection system for axial blood pumps
    Michael Vollkron
    Department of Cardiothoracic Surgery and Ludwig Boltzmann Institute for Cardiosurgical Research, Vienna, Austria
    Artif Organs 28:709-16. 2004
    ..This system will be integrated into an automatic pump speed control system to provide adequate perfusion for the LVAD recipient, without excessive unloading of the ventricle...
  15. doi Off-pump HeartWare ventricular assist device implantation with outflow graft anastomosis to the left subclavian artery
    Julia Riebandt
    Department of Cardiac Surgery, Medical University Vienna, Vienna, Austria
    Ann Thorac Surg 97:2214-6. 2014
    ..This technique is especially appealing in redo cases as well as in patients with significant calcifications of the ascending aorta or in destination-therapy patients. ..
  16. doi Renal function after implantation of continuous versus pulsatile flow left ventricular assist devices
    Sigrid E Sandner
    Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria
    J Heart Lung Transplant 27:469-73. 2008
    ..This study was designed to determine the effect of continuous vs pulsatile flow devices on renal function after left ventricular assist device (LVAD) implantation...
  17. doi A passive magnetically and hydrodynamically suspended rotary blood pump
    Martin Stoiber
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Waehringer Guertel 18 20, Vienna, Austria
    Artif Organs 33:250-7. 2009
    ..Further study is needed to optimize the magnetic drive unit and to ascertain its ability to withstand inertial loads imposed by sudden movements and external shock...
  18. doi Preoperative patient optimization using extracorporeal life support improves outcomes of INTERMACS Level I patients receiving a permanent ventricular assist device
    Julia Riebandt
    Department of Cardiac Surgery, Medical University Vienna, Vienna, Austria
    Eur J Cardiothorac Surg 46:486-92; discussion 492. 2014
    ..We report our experience with a bridge-to-bridge concept consisting of initial veno-arterial extracorporeal life support (ECLS) and deferral of VAD implantation to recovery of end-organ function in INTERMACS Level I patients...
  19. doi Usability and safety of ventricular assist devices: human factors and design aspects
    Lorenz Geidl
    Center of Biomedical Engineering and Physics, Medical University of Vienna, Vienna, Austria
    Artif Organs 33:691-5. 2009
    ..No correlation between the assessed manual skills and the number of adverse events was found. To conclude, this preliminary study revealed considerable potential for improvements in the usability of ventricular assist systems...
  20. doi Low-molecular-weight heparin for anti-coagulation after left ventricular assist device implantation
    Sigrid E Sandner
    Division of Cardiac Surgery, Medical University of Vienna, Vienna, Austria Electronic address
    J Heart Lung Transplant 33:88-93. 2014
    ..We evaluated the feasibility of low-molecular-weight heparin (LMWH) for initiation of anti-coagulation and transitioning to oral anti-coagulation after LVAD implantation...
  21. doi Left ventricle afterload impedance control by an axial flow ventricular assist device: a potential tool for ventricular recovery
    Francesco Moscato
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria
    Artif Organs 34:736-44. 2010
    ..This, in turn, may represent a potential additional tool to increase the number of patients showing recovery...
  22. doi Coronary hemodynamics and myocardial oxygen consumption during support with rotary blood pumps
    Peter Voitl
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Vienna, Austria
    Artif Organs 33:77-80. 2009
    ..These results show that blood flow in the coronary arteries is not affected by flow changes imposed by rotary blood pumps. An undiminished coronary perfusion at falling oxygen consumption might contribute to cardiac recovery...
  23. doi Low molecular weight heparin as an alternative to unfractionated heparin in the immediate postoperative period after left ventricular assist device implantation
    Sigrid E Sandner
    Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria
    Artif Organs 32:819-22. 2008
    ..In two patients, pump thrombosis was suspected. There were two ischemic and no hemorrhagic strokes. The use of LMWH may provide a new anticoagulation treatment option in the immediate postoperative period after LVAD implantation...
  24. ncbi Dynamic modeling and identification of an axial flow ventricular assist device
    Francesco Moscato
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Vienna, Austria
    Int J Artif Organs 32:336-43. 2009
    ..For a particular pump, a reliable mathematical model was identified that correctly reproduced the relationship between instantaneous VAD flow, head and impeller speed...
  25. doi Viennese approach to minimize the invasiveness of ventricular assist device implantation†
    Thomas Haberl
    Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria
    Eur J Cardiothorac Surg 46:991-6; discussion 996. 2014
    ..We present the surgical techniques and the initial clinical experience...
  26. doi Fixation and mounting of porcine aortic valves for use in mock circuits
    Thomas Schlöglhofer
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna Austria and Department of Cardiac Surgery, Medical University of Vienna, Vienna Austria and Ludwig Boltzmann Cluster for Cardiovascular Research, Vienna Austria
    Int J Artif Organs 36:738-41. 2013
    ..Therefore, we developed a cheap, fast, alternative method to mount valves obtained from the slaughterhouse in mock circuits...
  27. ncbi Suction events during left ventricular support and ventricular arrhythmias
    Michael Vollkron
    Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria
    J Heart Lung Transplant 26:819-25. 2007
    ..In this study we report severe ventricular arrhythmias closely related to suction events in rotary blood pumps, a phenomenon that has not been described previously...
  28. ncbi The DuraHeart VAD, a magnetically levitated centrifugal pump: the University of Vienna bridge-to-transplant experience
    Tomohiro Nishinaka
    Department of Cardiothoracic Surgery, Medical University of Vienna, A 1090 Vienna, Austria
    Circ J 70:1421-5. 2006
    ..The clinical application of the DuraHeart (Terumo Heart Inc, USA) has begun in Europe as a clinical trial of a third-generation implantable centrifugal blood pump. Four successful clinical implants are presented...
  29. doi Interaction of a Transapical Miniaturized Ventricular Assist Device With the Left Ventricle: Hemodynamic Evaluation and Visualization in an Isolated Heart Setup
    Marcus Granegger
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna
    Artif Organs 40:1113-1120. 2016
    ..The isolated heart is a simple, accessible evaluation platform unaffected by complex reactions within a whole, living animal. This platform allowed detection and visualization of potential hazards...
  30. doi High-Intensity Transient Signals in the Outflow Graft and Thrombosis of a HeartWare Left Ventricular Assist Device
    Kamen Dimitrov
    Division of Cardiac Surgery, Medical University of Vienna, Vienna, Austria
    Ann Thorac Surg 101:e83-5. 2016
    ..In this case it was a specific sign associated with device thrombosis that resolved after successful treatment with systemic thrombolysis. ..
  31. doi Rapid induction of mild therapeutic hypothermia by extracorporeal veno-venous blood cooling in humans
    Christoph Testori
    Department of Emergency Medicine, Medical University of Vienna, Austria
    Resuscitation 84:1051-5. 2013
    ..The aim of this study was to evaluate the efficacy and safety of extracorporeal veno-venous blood cooling in humans successfully resuscitated from cardiac arrest...
  32. doi Repair of left ventricular assist device driveline damage directly at the transcutaneous exit site
    Heinrich Schima
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria Ludwig Boltzmann Cluster for Cardiovascular Research, Vienna, Austria
    Artif Organs 38:422-5. 2014
    ..In conclusion, this method allows a quick stabilization and repair of damaged driveline isolations even near the exit site, resulting in a biocompatible surface and consistent flexibility of the cable. ..
  33. ncbi Emergency reinforcement of cracked paracorporeal blood pumps
    Heinrich Schima
    Department of Biomedical Engineering and Physics, Medical University of Vienna, Vienna, Austria
    ASAIO J 50:621-3. 2004
    ..It is concluded that a carefully selected gluing procedure (caveats: with previously tested glue, a validated procedure, and as a last resort only) may bring less risk in such rare cases of pump cracks than a pump exchange...
  34. doi Sternal force distribution during median sternotomy retraction
    Philipp Aigner
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria Ludwig Boltzmann Cluster for Cardiovascular Research, Vienna, Austria Electronic address
    J Thorac Cardiovasc Surg 146:1381-6. 2013
    ..The aim of this study was to determine the effects of retractor shape on local force distribution to obtain criteria for retractor design...
  35. doi An alternative method to create highly transparent hollow models for flow visualization
    Martin Stoiber
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna Austria
    Int J Artif Organs 36:131-4. 2013
    ..In this work an alternative method is presented using chocolate as the fluid-space molding material...
  36. doi Evaluation of left ventricular relaxation in rotary blood pump recipients using the pump flow waveform: a simulation study
    Francesco Moscato
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, AKH 4L, Waehringer Guertel18 20, 1090 Vienna, Austria
    Artif Organs 36:470-8. 2012
    ..In conclusion, at least in simulation, relaxation can be derived from pump data. This noninvasively accessible information could contribute to a continuous estimation of the remaining cardiac function and its eventual recovery...
  37. doi Experimental acute type B aortic dissection: different sites of primary entry tears cause different ways of propagation
    Tomasz Dziodzio
    Center for Medical Physics and Biomedical Engineering, Medical University Vienna Ludwig Boltzmann Cluster for Cardiovascular Research, and Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria
    Ann Thorac Surg 91:724-7. 2011
    ..The aim of the study was to evaluate different sites of primary entry tears and the propagation of the dissecting membrane, antegrade and retrograde, in an experimental model of acute type B aortic dissection...
  38. doi Intuitive use and usability of ventricular assist device peripheral components in simulated emergency conditions
    Lorenz Geidl
    Department of Medical Physics and Biomedical Engineering, Medical University of Vienna Ludwig Boltzmann Cluster for Cardiovascular Research, Vienna, Austria
    Artif Organs 35:773-80. 2011
    ....
  39. ncbi Automatic system for noninvasive blood pressure determination in rotary pump recipients
    Heinrich Schima
    Department of Cardiothoracic Surgery and LBI of Cardiosurgical Research, University of Vienna, Vienna, Austria
    Artif Organs 28:451-7. 2004
    ..By development of a wristwatch sensor and an automatic control system a robust method for daily use could be developed...
  40. ncbi Physiology of continuous blood flow in recipients of rotary cardiac assist devices
    Markus Thalmann
    Department of Cardio Thoracic Surgery, and LBI for Cardio Surgical Research, University of Vienna, Vienna, Austria
    J Heart Lung Transplant 24:237-45. 2005
    ..Therefore, this review summarizes the observed clinical consequences of continuous blood flow in patients supported by rotary blood pumps and relates these consequences to underlying experimental studies...
  41. doi Daily life activity in patients with left ventricular assist devices
    Marcus Granegger
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna Austria
    Int J Artif Organs 39:22-7. 2016
    ..The aim of this study was to assess the postoperative activity of LVAD patients using actigraphy and to compare these patients to a healthy and a heart-transplanted (HTx) population...
  42. ncbi Myocardial recovery in peripartum cardiomyopathy after hyperprolactinemia treatment on BIVAD
    Dominik Wiedemann
    Department for Cardiac Surgery, Medical University of Vienna, Austria Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria Ludwig Boltzmann Cluster for Cardiovascular Research, Vienna, Austria, Department for Cardiovascular Anaesthesia, Medical University of Vienna, Austria
    ASAIO J . 2016
    ..Implantation of a biventricular ventricular assist device was performed, additonally the patient's hyperprolactinemia was treated with Cabergoline resulting in a fast complete restoration of ventricular function...
  43. doi The influence of bicuspid aortic valves on the dynamic pressure distribution in the ascending aorta: a porcine ex vivo model
    Andrzej Juraszek
    Center for Medical Physics and Biomedical Engineering, Vienna, Austria Ludwig Boltzmann Cluster for Cardiovascular Research, Vienna, Austria Department of Cardiac Surgery and Transplantation, The Cardinal Stefan Wyszyński Institute of Cardiology, Warsaw, Poland
    Eur J Cardiothorac Surg 46:349-55; discussion 355. 2014
    ..The aim of the study was to simulate the effect of different bicuspid aortic valve configurations on the dynamic pressure distribution in the ascending aorta...
  44. ncbi Left ventricular pressure-volume loop analysis during continuous cardiac assist in acute animal trials
    Francesco Moscato
    Department of Biomedical Engineering and Physics, Medical University of Vienna, Vienna, Austria
    Artif Organs 31:369-76. 2007
    ..SVI becomes slightly dependent on EDVI, which may be due to autoregulatory mechanisms...
  45. doi Systemic pressure does not directly affect pressure gradient and valve area estimates in aortic stenosis in vitro
    Julia Mascherbauer
    Department of Cardiology, Medical University of Vienna, Vienna General Hospital, Vienna, Austria
    Eur Heart J 29:2049-57. 2008
    ..Hypertension is a frequent finding in patients with aortic stenosis (AS). However, controversial data about the influence of systemic blood pressure on the quantification of AS have been published...
  46. doi Electrospun polyurethane vascular grafts: in vitro mechanical behavior and endothelial adhesion molecule expression
    Christian Grasl
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Vienna, Austria
    J Biomed Mater Res A 93:716-23. 2010
    ..The synthetic graft surface neither impaired the endothelial response toward IL-1beta stimulation nor did it adversely affect the regulation of expression of endothelial adhesion molecules...
  47. ncbi Choroidal microcirculation in patients with rotary cardiac assist device
    Elzbieta Polska
    Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria
    J Heart Lung Transplant 26:572-8. 2007
    ..With these pumps, the pulsatility of arterial blood flow and arterial pressure pulse is considerably reduced. Effects on end-organ perfusion, particularly microcirculation, have been assessed...
  48. ncbi Endocrine function is not impaired in patients with a continuous MicroMed-DeBakey axial flow pump
    Georg M Wieselthaler
    Department of Cardiothoracic Surgery, University of Vienna, Vienna, Austria
    J Thorac Cardiovasc Surg 133:2-6. 2007
    ..Patients with implanted MicroMed-DeBakey axial pumps show nonphysiologic low-pulsatile blood flow profiles, and therefore it appeared to be of interest to evaluate their possible effect on the endocrine system...
  49. doi Mesh fixation in laparoscopic incisional hernia repair: glue fixation provides attachment strength similar to absorbable tacks but differs substantially in different meshes
    Erwin Rieder
    Department of General Surgery, Medical of University Vienna, Austria
    J Am Coll Surg 212:80-6. 2011
    ..It was hypothesized that particular mesh structures would substantially influence detachment force...
  50. pmc Biocompatibility Assessment of a New Biodegradable Vascular Graft via In Vitro Co-culture Approaches and In Vivo Model
    Marjan Enayati
    Division of Biomedical Research, Medical University of Vienna, Vienna, Austria
    Ann Biomed Eng 44:3319-3334. 2016
    ..This study established an exciting approach developing a co-culture model as a tool for biocompatibility evaluation of degradable biomaterials...
  51. doi Biodegradable, thermoplastic polyurethane grafts for small diameter vascular replacements
    Helga Bergmeister
    Division of Biomedical Research, Medical University of Vienna, Austria Ludwig Boltzmann Cluster for Cardiovascular Research, Vienna, Austria Electronic address
    Acta Biomater 11:104-13. 2015
    ..Degradable grafts showed equivalent long-term performance characteristics compared to the clinically used, non-degradable material with improvements in intimal hyperplasia and ingrowth of host cells...
  52. doi Assessment of aortic valve opening during rotary blood pump support using pump signals
    Marcus Granegger
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria Ludwig Boltzmann Cluster for Cardiovascular Research, Vienna, Austria
    Artif Organs 38:290-7. 2014
    ..This algorithm makes the evaluation of the state of the AV possible from pump data only, allowing pump speed adjustment for a frequent opening of the AV and providing information about the interaction of the native heart with the RBP. ..
  53. doi Continuous monitoring of cardiac rhythms in left ventricular assist device patients
    Francesco Moscato
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria Ludwig Boltzmann Cluster for Cardiovascular Research, Vienna, Austria
    Artif Organs 38:191-8. 2014
    ..3 ± 1.0%. Continuous monitoring of cardiac rhythms from available pump data is possible. It has the potential to reduce the out-of-hospital diagnostic burden and to permit a more efficient adjustment of the level of mechanical support...
  54. ncbi Interaction of the cardiovascular system with an implanted rotary assist device: simulation study with a refined computer model
    Michael Vollkron
    Department of Cardiothoracic Surgery and Ludwig Boltzmann Institute for Cardiosurgical Research, Vienna, Austria
    Artif Organs 26:349-59. 2002
    ..It can be used for the investigation of various clinical and control questions in normal and pathological conditions of the left ventricular assist device recipient...
  55. doi Minimally invasive thoratec Heartmate II implantation in the setting of severe thoracic aortic calcification
    Julia Riebandt
    Department of Cardiac Surgery, Medical University Vienna, Vienna, Austria
    Ann Thorac Surg 96:1094-6. 2013
    ..This technique is especially appealing in patients with generalized aortic calcification undergoing LVAD implantation. ..
  56. doi Debate: creating adequate pulse with a continuous flow ventricular assist device: can it be done and should it be done? Probably not, it may cause more problems than benefits!
    Heinrich Schima
    aDepartment of Cardiac Surgery, Clinic of Surgery bCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna cLudwig Boltzmann Cluster for Cardiovascular Research, Vienna, Austria
    Curr Opin Cardiol 31:337-42. 2016
    ..This review discusses recent technical and clinical findings to answer whether such intervention should be implemented in the standard patient management...
  57. ncbi Evaluation of the HeartWare ventricular assist device Lavare cycle in a particle image velocimetry model and in clinical practice
    Daniel Zimpfer
    Department of Surgery, Division of Cardiac Surgery, Medical University of Vienna, Vienna, Austria
    Eur J Cardiothorac Surg 50:839-848. 2016
    ..Here, we report in vitro and clinical findings on the effects of the Lavare cycle...
  58. pmc Electrospinning of aligned fibers with adjustable orientation using auxiliary electrodes
    Matthias M L Arras
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, 1090 Vienna, Austria Institute for Material Science and Technology, Friedrich Schiller University, 07743 Jena, Germany
    Sci Technol Adv Mater 13:035008. 2012
    ..This study comprehensively documents the feasibility of directed fiber deposition and offers an easy upgrade to existing electrospinning setups...
  59. doi Acquired von Willebrand factor deficiency caused by LVAD is ADAMTS-13 and platelet dependent
    Petra Jilma-Stohlawetz
    Department of Laboratory Medicine, Division of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, Austria
    Thromb Res 137:196-201. 2016
    ..We hypothesised that an ex vivo model could be established to study whether mechanical shear stress alone causes aVWD or whether this process depends also on the VWF cleavage protein ADAMTS-13 and on platelets...
  60. doi Usability of ventricular assist devices in daily experience: a multicenter study
    Heinrich Schima
    Center for Medical Physics and Biomedical Engineering, Department of Cardiac Surgery, Ludwig Boltzmann Cluster for Cardiovascular Research, Medical University of Vienna, Vienna, Austria
    Artif Organs 38:751-60. 2014
    ..This first multicenter study on VAD usability reveals considerable differences among devices and centers. The comparative assessment aims to help optimize device design, patient management, and training. ..
  61. doi Activated Schwann Cell-Like Cells on Aligned Fibrin-Poly(Lactic-Co-Glycolic Acid) Structures: A Novel Construct for Application in Peripheral Nerve Regeneration
    Christina M A P Schuh
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, AUVA Research Center, Vienna, Austria
    Cells Tissues Organs 200:287-99. 2014
    ..Aligned electrospun fibrin-PLGA fibers promoted the formation of Büngner-like structures in SCLs, which also rolled the fibrin-PLGA matrix into a tubular scaffold. These in vitro findings favor further in vivo testing. ..
  62. doi Semi-invasive measurement of cardiac output based on pulse contour: a review and analysis
    Thomas Schlöglhofer
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, AKH 4L, Waehringer Guertel 18 20, 1090, Vienna, Austria
    Can J Anaesth 61:452-79. 2014
    ..The five investigated systems are FloTrac/Vigileo(®), PiCCO(®), LiDCO/PulseCO(®), PRAM/MostCare(®), and Modelflow...
  63. ncbi Special considerations on the implantation technique for the MicroMed-DeBakey ventricular assist device axial pump
    Georg M Wieselthaler
    Department of Cardiothoracic Surgery and Ludwig Boltzmann Institute for Cardiosurgical Research, University of Vienna, Vienna, Austria
    Ann Thorac Surg 76:2109-11. 2003
    ..3 +/- 0.6 to 6.7 +/- 0.3 L/min), and to facilitate the subsequent transplantation...
  64. doi Biomechanical properties of decellularized porcine pulmonary valve conduits
    Gernot Seebacher
    Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria
    Artif Organs 32:28-35. 2008
    ..01) and transverse (decellularized: +126%, P < 0.001; decellularized + cryopreserved: +118%, P < 0.001) direction. Again, cryopreservation did not influence the biomechanical properties of the decellularized porcine matrix...
  65. ncbi Value and limitations of aortic valve resistance with particular consideration of low flow-low gradient aortic stenosis: an in vitro study
    Julia Mascherbauer
    Department of Bioengineering, Vienna General Hospital, University of Vienna, Vienna, Austria
    Eur Heart J 25:787-93. 2004
    ..Even more importantly, valve resistance has been reported to distinguish between truly severe and "pseudosevere" AS in patients with low cardiac output. However, the diagnostic value of valve resistance remains controversial...
  66. ncbi Enhanced endothelial cell retention on shear-stressed synthetic vascular grafts precoated with RGD-cross-linked fibrin
    Johann G Meinhart
    First Department of Surgery, Hospital Lainz, Vienna, Austria
    Tissue Eng 11:887-95. 2005
    ..The failure of higher RGD concentrations to enhance endothelial cell attachment may be explained by competitive binding of endothelial cells to non-cross-linked RGD...
  67. ncbi Fluid dynamics, wall mechanics, and oxygen transfer in peripheral bypass anastomoses
    Karl Perktold
    Institute of Mathematics, Graz University of Technology, Austria
    Ann Biomed Eng 30:447-60. 2002
    ....
  68. ncbi Building a computer model of the Haemobear blood pump
    Thomas Grönsfelder
    Department of Mechatronics and Machine Acoustics, Darmstadt University of Technology, Darmstadt, Germany
    Artif Organs 27:931-4. 2003
    ..The output of these codes has to be postprocessed to get the desired values for Simulink. This article will give an overview of how to implement arbitrary physical influences on the rotor in a computational model of the complete pump...
  69. ncbi Effect of continuous arterial blood flow in patients with rotary cardiac assist device on the washout of a stenosis wake in the carotid bifurcation: a computer simulation study
    Martin Prosi
    MOX, Department of Mathematics, Politecnico di Milano, Milan, Italy
    J Biomech 40:2236-43. 2007
    ..Therefore, from the point of macroscopic flow field analysis, continuous flow should not enhance the thromboembolic risk in ventricular assist device recipients...
  70. ncbi Doppler assessment of mechanical aortic valve prostheses: effect of valve design and size of the aorta
    Julia Mascherbauer
    Department of Cardiology, University of Vienna, Vienna General Hospital, Austria
    J Heart Valve Dis 13:823-30. 2004
    ..Variable results have been reported for tilting-disc prostheses. In addition, the effect of aortic size on the Doppler-catheter gradient relationship remains unclear...
  71. ncbi Weaning of rotary blood pump recipients after myocardial recovery: a computer study of changes in cardiac energetics
    Heinrich Schima
    Department of Cardio Thoracic Surgery and LBI of Cardio Surgical Research, University of Vienna, Austria
    J Thorac Cardiovasc Surg 127:1743-50. 2004
    ..Rotary pumps offer training advantages when support flow is reduced, even to nearly zero. We report a computer analysis that evaluates the work required of the heart during partial unloading and removal of rotary pumps...
  72. ncbi Numerical study of hemodynamics and wall mechanics in distal end-to-side anastomoses of bypass grafts
    Armin Leuprecht
    Institute of Mathematics, Technical University Graz, Steyrergasse 30 3, A 8010 Graz, Austria
    J Biomech 35:225-36. 2002
    ..The wall mechanical studies show that increased compliance mismatch leads to increased intramural stresses, and thus, may have a proliferative influence on suture line hyperplasia, as it is observed in the in vivo study...
  73. ncbi Extensive coagulation monitoring in patients after implantation of the MicroMed Debakey continuous flow axial pump
    Nikolaos Bonaros
    Department of Cardiothoracic Surgery, University of Vienna, Austria
    ASAIO J 50:424-31. 2004
    ..Aspirin and dipyridamole therapy in addition to oral anticoagulation using phenprocoumon may contribute to platelet function and clot mechanics restoration and is, therefore, recommended for patients after VAD implantation...
  74. ncbi Comparison of the autoregulatory mechanisms between middle cerebral artery and ophthalmic artery after thigh cuff deflation in healthy subjects
    Julia Kolodjaschna
    Department of Clinical Pharmacology, Medical Univerity of Vienna, A 1090 Vienna, Austria
    Invest Ophthalmol Vis Sci 46:636-40. 2005
    ..To compare dynamic autoregulation in the middle cerebral artery (MCA) and the ophthalmic artery (OA) after a step decrease in systemic blood pressure...