Raimund Helbok

Summary

Affiliation: Innsbruck Medical University
Country: Austria

Publications

  1. doi request reprint Severe Plasmodium falciparum malaria with peripheral gangrene
    Raimund Helbok
    Clinical Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    Lancet Infect Dis 8:400. 2008
  2. pmc High dose erythropoietin increases brain tissue oxygen tension in severe vasospasm after subarachnoid hemorrhage
    Raimund Helbok
    Neurological Intensive Care Unit, Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    BMC Neurol 12:32. 2012
  3. pmc Early brain injury after aneurysmal subarachnoid hemorrhage: a multimodal neuromonitoring study
    Raimund Helbok
    Neurological Intensive Care Unit, Department of Neurology, Medical University of Innsbruck, Anichstreet 35, 6020, Innsbruck, Austria
    Crit Care 19:75. 2015
  4. doi request reprint Early brain injury after aneurysmal subarachnoid hemorrhage a multimodal neuromonitoring study
    Raimund Helbok
    Neurological Intensive Care Unit, Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    Crit Care 19:809. 2015
  5. doi request reprint Intracranial pressure and cerebral perfusion pressure monitoring in non-TBI patients: special considerations
    Raimund Helbok
    Department of Neurology, Neurocritical Care Unit, Innsbruck Medical University, Anichstr 35, 6020, Innsbruck, Austria
    Neurocrit Care 21:S85-94. 2014
  6. doi request reprint Multimodal invasive monitoring in status epilepticus: what is the evidence it has a place?
    Raimund Helbok
    Department of Neurology, Division of Neurocritical Care, Innsbruck Medical University, Anichstrasse 35, Innsbruck, Austria
    Epilepsia 54:57-60. 2013
  7. doi request reprint Systemic glucose and brain energy metabolism after subarachnoid hemorrhage
    Raimund Helbok
    Division of Critical Care Neurology, Department of Neurology, Columbia University Medical Center, Milstein Hospital 8 Center, 177 Fort Washington Ave, New York, NY 10032, USA
    Neurocrit Care 12:317-23. 2010
  8. doi request reprint Multimodal neuromonitoring in a patient with aneurysmal subarachnoid hemorrhage associated with aortic coarctation
    Raimund Helbok
    Neurological Intensive Care Unit, Clinical Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    Neurocrit Care 14:433-7. 2011
  9. doi request reprint Intracerebral monitoring of silent infarcts after subarachnoid hemorrhage
    Raimund Helbok
    Division of Critical Care Neurology, Department of Neurology, Columbia University Medical Center, Milstein Hospital 8 Center 177 Fort Washington Ave, New York, NY 10032, USA
    Neurocrit Care 14:162-7. 2011
  10. doi request reprint The Lambaréné Organ Dysfunction Score (LODS) is a simple clinical predictor of fatal malaria in African children
    Raimund Helbok
    Medical Research Unit, Albert Schweitzer Hospital, Lambarene, Gabon
    J Infect Dis 200:1834-41. 2009

Detail Information

Publications71

  1. doi request reprint Severe Plasmodium falciparum malaria with peripheral gangrene
    Raimund Helbok
    Clinical Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    Lancet Infect Dis 8:400. 2008
  2. pmc High dose erythropoietin increases brain tissue oxygen tension in severe vasospasm after subarachnoid hemorrhage
    Raimund Helbok
    Neurological Intensive Care Unit, Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    BMC Neurol 12:32. 2012
    ..In this study, the authors aimed to investigate the effect of EPO on cerebral metabolism and brain tissue oxygen tension (PbtO2)...
  3. pmc Early brain injury after aneurysmal subarachnoid hemorrhage: a multimodal neuromonitoring study
    Raimund Helbok
    Neurological Intensive Care Unit, Department of Neurology, Medical University of Innsbruck, Anichstreet 35, 6020, Innsbruck, Austria
    Crit Care 19:75. 2015
    ....
  4. doi request reprint Early brain injury after aneurysmal subarachnoid hemorrhage a multimodal neuromonitoring study
    Raimund Helbok
    Neurological Intensive Care Unit, Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    Crit Care 19:809. 2015
    ....
  5. doi request reprint Intracranial pressure and cerebral perfusion pressure monitoring in non-TBI patients: special considerations
    Raimund Helbok
    Department of Neurology, Neurocritical Care Unit, Innsbruck Medical University, Anichstr 35, 6020, Innsbruck, Austria
    Neurocrit Care 21:S85-94. 2014
    ..Although the influence of ICP-based care on outcome in non-TBI conditions appears less robust than in TBI, monitoring ICP and cerebral perfusion pressure can play a role in guiding therapy in select patients. ..
  6. doi request reprint Multimodal invasive monitoring in status epilepticus: what is the evidence it has a place?
    Raimund Helbok
    Department of Neurology, Division of Neurocritical Care, Innsbruck Medical University, Anichstrasse 35, Innsbruck, Austria
    Epilepsia 54:57-60. 2013
    ..In the future, this information can potentially provide integrated pathophysiologic end points into SE treatment concepts. ..
  7. doi request reprint Systemic glucose and brain energy metabolism after subarachnoid hemorrhage
    Raimund Helbok
    Division of Critical Care Neurology, Department of Neurology, Columbia University Medical Center, Milstein Hospital 8 Center, 177 Fort Washington Ave, New York, NY 10032, USA
    Neurocrit Care 12:317-23. 2010
    ..We sought to determine if MC and LPR elevations after subarachnoid hemorrhage (SAH) are associated with acute reductions in serum glucose...
  8. doi request reprint Multimodal neuromonitoring in a patient with aneurysmal subarachnoid hemorrhage associated with aortic coarctation
    Raimund Helbok
    Neurological Intensive Care Unit, Clinical Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    Neurocrit Care 14:433-7. 2011
    ..Aortic coarctation (AC) rarely remains undiagnosed until adulthood. Intracranial aneurysms and spontaneous subarachnoid hemorrhage (SAH) are more frequent in patients with AC than in the general population...
  9. doi request reprint Intracerebral monitoring of silent infarcts after subarachnoid hemorrhage
    Raimund Helbok
    Division of Critical Care Neurology, Department of Neurology, Columbia University Medical Center, Milstein Hospital 8 Center 177 Fort Washington Ave, New York, NY 10032, USA
    Neurocrit Care 14:162-7. 2011
    ..Silent infarction is common in poor-grade subarachnoid hemorrhage (SAH) patients and associated with poor outcome. Invasive neuromonitoring devices may detect changes in cerebral metabolism and oxygenation...
  10. doi request reprint The Lambaréné Organ Dysfunction Score (LODS) is a simple clinical predictor of fatal malaria in African children
    Raimund Helbok
    Medical Research Unit, Albert Schweitzer Hospital, Lambarene, Gabon
    J Infect Dis 200:1834-41. 2009
    ..Identifying those individuals who are likely to die is crucial. Several factors have been independently associated with death. Because malaria is a systemic disease, a quantitative score combining such risk factors may be superior...
  11. doi request reprint Tuberous sclerosis complex with unilateral perisylvian polymicrogyria and contralateral hippocampal sclerosis - a case report
    R Helbok
    Department of Neurology, Innsbruck Medical University, Anichstrasse 35, A 6020 Innsbruck, Austria
    Seizure 18:303-5. 2009
    ..However, on MRI multiple potentially epileptogenic lesions were identified. The neurobiological background of the coexistence of different types of malformations of cortical development remains enigmatic...
  12. doi request reprint Reduced brain/serum glucose ratios predict cerebral metabolic distress and mortality after severe brain injury
    Pedro Kurtz
    Neurological Intensive Care Unit, Departments of Neurology and Neurosurgery, Columbia University College of Physicians and Surgeons, Milstein Hospital 8 Center, 177 Fort Washington Ave, New York, NY, 10032, USA
    Neurocrit Care 19:311-9. 2013
    ..We sought to evaluate the potential importance of impaired glucose transport by assessing the relationship between brain/serum glucose ratios, cerebral metabolic distress, and mortality after severe brain injury...
  13. doi request reprint Effect of mannitol on brain metabolism and tissue oxygenation in severe haemorrhagic stroke
    Raimund Helbok
    Division of Neurocritical Care, Department of Neurology, Columbia University Medical Center, Milstein Hospital 8 300 Center, New York, NY 10032, USA
    J Neurol Neurosurg Psychiatry 82:378-83. 2011
    ..The authors examined if mannitol treatment of raised intracranial pressure will result in an improvement in brain metabolism together with the expected drop in intracranial pressure (ICP)...
  14. doi request reprint Endovascular cooling and endothelial activation in hemorrhagic stroke patients
    Marlene Fischer
    Department of Neurology, Neurologic Intensive Care Unit, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria
    Neurocrit Care 17:224-30. 2012
    ..This analysis was designed to measure the endothelial markers Angiopoietin-1 (Ang-1) and -2 (Ang-2) in endovascularly based prophylactic normothermia versus conventional temperature management...
  15. doi request reprint Global cerebral edema and brain metabolism after subarachnoid hemorrhage
    Raimund Helbok
    Division of Critical Care Neurology, Department of Neurology, Columbia University Medical Center, New York, NY 10032, USA
    Stroke 42:1534-9. 2011
    ..Global cerebral edema is common among patients with poor-grade subarachnoid hemorrhage and is associated with poor outcome. Currently no targeted therapy exists largely due to an incomplete understanding of the underlying mechanisms...
  16. doi request reprint Soluble endoglin and transforming growth factor-β₁ and the development of vasospasm after spontaneous subarachnoid hemorrhage: a pilot study
    Anelia Dietmann
    Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    Cerebrovasc Dis 33:16-22. 2012
    ..Alteration of vasomotor tone has been postulated as an important factor in the pathogenesis of CVS. Members of the transforming growth factor-β (TGF-β) family and their receptors have been implicated in the regulation of vascular tone...
  17. doi request reprint Endoglin in African children with Plasmodium falciparum malaria: a novel player in severe malaria pathogenesis?
    Anelia Dietmann
    Clinical Department of Neurology, Innsbruck Medical University, 6020 Innsbruck, Austria
    J Infect Dis 200:1842-8. 2009
    ..Transforming growth factor beta (TGF-beta) family members are important regulators of inflammation that influence malaria pathogenesis. The soluble form of the auxiliary receptor endoglin (sEng) may play a role in malaria pathogenesis...
  18. doi request reprint Prophylactic, endovascularly based, long-term normothermia in ICU patients with severe cerebrovascular disease: bicenter prospective, randomized trial
    Gregor Broessner
    Department of Neurology, Neurologic Intensive Care Unit, Innsbruck Medical University, Innsbruck, Austria
    Stroke 40:e657-65. 2009
    ....
  19. pmc Multimodality monitoring for cerebral perfusion pressure optimization in comatose patients with intracerebral hemorrhage
    Sang Bae Ko
    Department of Neurology, Columbia University College of Physicians and Surgeons, 177 Fort Washington Ave, New York, NY 10032, USA
    Stroke 42:3087-92. 2011
    ..We sought to determine the feasibility of brain multimodality monitoring for optimizing CPP and potentially reducing secondary brain injury after intracerebral hemorrhage...
  20. pmc Glatiramer acetate reduces the risk for experimental cerebral malaria: a pilot study
    Peter Lackner
    Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    Malar J 8:36. 2009
    ....
  21. pmc Cerebral perfusion pressure thresholds for brain tissue hypoxia and metabolic crisis after poor-grade subarachnoid hemorrhage
    J Michael Schmidt
    Neurological Intensive Care Unit, Department of Neurology, Columbia University Medical Center, and Milstein Hospital, 177 Fort Washington, 8 300, New York, NY 10032, USA
    Stroke 42:1351-6. 2011
    ..To identify a minimally acceptable cerebral perfusion pressure threshold above which the risks of brain tissue hypoxia (BTH) and oxidative metabolic crisis are reduced for patients with subarachnoid hemorrhage (SAH)...
  22. pmc Opposed circulating plasma levels of endothelin-1 and C-type natriuretic peptide in children with Plasmodium falciparum malaria
    Anelia Dietmann
    Clinical Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    Malar J 7:253. 2008
    ....
  23. pmc Differential regulation of matrix-metalloproteinases and their tissue inhibitors in patients with aneurysmal subarachnoid hemorrhage
    Marlene Fischer
    Department of Neurology, Innsbruck Medical University, Innsbruck, Austria mail
    PLoS ONE 8:e59952. 2013
    ..This study aimed to analyze MMP-3, MMP-9, TIMP-1 and TIMP-3 in patients with SAH and their respective association with cerebral vasospasm (CVS)...
  24. doi request reprint Anemia is associated with metabolic distress and brain tissue hypoxia after subarachnoid hemorrhage
    Pedro Kurtz
    Division of Critical Care Neurology, Department of Neurology, Columbia University, Milstein Hospital 8 Center, New York, NY 10032, USA
    Neurocrit Care 13:10-6. 2010
    ..The objective of this study is to assess whether there is an association between anemia and metabolic distress or brain tissue hypoxia in patients with subarachnoid hemorrhage...
  25. doi request reprint Keep the brain cool--endovascular cooling in patients with severe traumatic brain injury: a case series study
    Marlene Fischer
    Department of Neurology, Neurologic Intensive Care Unit, Innsbruck Medical University, Innsbruck, Austria
    Neurosurgery 68:867-73; discussion 873. 2011
    ..As brain temperature is reported to be extensively higher than core body temperature in traumatic brain injury (TBI) patients, posttraumatic hyperthermia is of particular relevance in the injured brain...
  26. doi request reprint Multimodality neuromonitoring and decompressive hemicraniectomy after subarachnoid hemorrhage
    Robert Morgan Stuart
    Department of Neurological Surgery, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Neurocrit Care 15:146-50. 2011
    ....
  27. doi request reprint Intracortical EEG for the detection of vasospasm in patients with poor-grade subarachnoid hemorrhage
    R Morgan Stuart
    Department of Neurological Surgery, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Neurocrit Care 13:355-8. 2010
    ..To study the feasibility of utilizing intracortical electroencephalography (ICE) including quantitative EEG (qEEG) analysis for the detection of vasospasm in five consecutive poor-grade SAH patients...
  28. doi request reprint Quantitative analysis of hemorrhage volume for predicting delayed cerebral ischemia after subarachnoid hemorrhage
    Sang Bae Ko
    Department of Neurology, Columbia University College of Physicians and Surgeons, Milstein Hospital Building 8 Center, 177 Fort Washington Avenue, New York, NY 10032, USA
    Stroke 42:669-74. 2011
    ..Quantification of hemorrhage on digitized images may be a more accurate method for predicting DCI than qualitative scales...
  29. doi request reprint High-dose intra-arterial verapamil for the treatment of cerebral vasospasm after subarachnoid hemorrhage: prolonged effects on hemodynamic parameters and brain metabolism
    R Morgan Stuart
    Department of Neurological Surgery, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Neurosurgery 68:337-45; discussion 345. 2011
    ....
  30. pmc Angiopoietin-1 is associated with cerebral vasospasm and delayed cerebral ischemia in subarachnoid hemorrhage
    Marlene Fischer
    Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    BMC Neurol 11:59. 2011
    ..Angiopoietins may play an important role in the pathophysiology of cerebral vasospasm (CVS). Ang-1 and Ang-2 have not been investigated in this regard so far...
  31. doi request reprint Influence of prophylactic, endovascularly based normothermia on inflammation in patients with severe cerebrovascular disease: a prospective, randomized trial
    Gregor Broessner
    Department of Neurology, Neurologic Intensive Care Unit, Innsbruck Medical University, Austria
    Stroke 41:2969-72. 2010
    ..We analyzed the impact of long-term endovascularly based prophylactic normothermia versus conventional temperature management on inflammatory parameters in patients with severe cerebrovascular disease...
  32. doi request reprint Intracranial multimodal monitoring for acute brain injury: a single institution review of current practices
    R Morgan Stuart
    Department of Neurological Surgery, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Neurocrit Care 12:188-98. 2010
    ..Here we review our experience in a consecutive series of acutely brain injured patients who underwent multimodality monitoring...
  33. ncbi request reprint Neuroinflammation is Associated with Brain Extracellular TAU-Protein Release after Spontaneous Subarachnoid Hemorrhage
    Alois Josef Schiefecker
    Department of Neurology, Medical University of Innsbruck, Anichstrasse 35, A 6020 Innsbruck
    Curr Drug Targets . 2016
    ..We sought to study the association between brain extracellular interleukin (IL)-6 and TAU-protein levels as a surrogate marker for neuroinflammation and axonal injury in patients with poor grade aSAH...
  34. pmc Neuroglucopenia and Metabolic Distress in Two Patients with Viral Meningoencephalitis: A Microdialysis Study
    Mario Kofler
    Neurological Intensive Care Unit, Department of Neurology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria
    Neurocrit Care 25:273-81. 2016
    ..Underlying pathophysiologic mechanisms are incompletely understood and may be elucidated using invasive multimodal neuromonitoring techniques in humans...
  35. doi request reprint Fluid responsiveness and brain tissue oxygen augmentation after subarachnoid hemorrhage
    Pedro Kurtz
    Division of Critical Care Neurology, Department of Neurology, Columbia University, Milstein Hospital 8 Center, 177 Fort Washington Ave, New York, NY, 10032, USA
    Neurocrit Care 20:247-54. 2014
    ..The objective of this study was to investigate the relationship between cardiac index (CI) response to a fluid challenge and changes in brain tissue oxygen pressure (PbtO(2)) in patients with subarachnoid hemorrhage (SAH)...
  36. pmc Early neurological deterioration after subarachnoid haemorrhage: risk factors and impact on outcome
    Raimund Helbok
    Department of Neurology, Division of Neurocritical Care, Columbia University College of Physicians and Surgeons, New York, NY, USA
    J Neurol Neurosurg Psychiatry 84:266-70. 2013
    ..Early neurological deterioration occurs frequently after subarachnoid haemorrhage (SAH). The impact on hospital course and outcome remains poorly defined...
  37. ncbi request reprint Survival and long-term functional outcome in 1,155 consecutive neurocritical care patients
    Gregor Broessner
    Neurologic Intensive Care Unit, Clinical Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    Crit Care Med 35:2025-30. 2007
    ..To analyze survival, mortality, and long-term functional disability outcome and to determine predictors of unfavorable outcome in critically ill patients admitted to a neurologic intensive care unit (neuro-ICU)...
  38. doi request reprint Cellular microparticles as a marker for cerebral vasospasm in spontaneous subarachnoid hemorrhage
    Peter Lackner
    Department of Neurology, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria
    Stroke 41:2353-7. 2010
    ..We hypothesize that cellular microparticles (MP) play a role in the pathogenesis of CVS and may serve as biomarkers for CVS...
  39. pmc Continuous intra-arterial nimodipine infusion in refractory symptomatic vasospasm after subarachnoid hemorrhage
    Raimund Helbok
    Department of Neurology, Neurological Intensive Care Unit, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria
    Springerplus 5:1807. 2016
    ..The purpose of this report is to describe the successful management of severe refractory vasospasm with continuous intra-arterial nimodipine (IAN) treatment...
  40. doi request reprint Matrix metalloproteinases and their tissue inhibitors (TIMPs) in Plasmodium falciparum malaria: serum levels of TIMP-1 are associated with disease severity
    Anelia Dietmann
    Clinical Department of Neurology, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria
    J Infect Dis 197:1614-20. 2008
    ..The key inhibitors of MMPs are the tissue inhibitors of metalloproteinases (TIMPs)...
  41. doi request reprint Influence of red blood cell transfusion on mortality and long-term functional outcome in 292 patients with spontaneous subarachnoid hemorrhage
    Gregor Broessner
    Neurologic Intensive Care Unit, Innsbruck Medical University, Innsbruck, Austria
    Crit Care Med 37:1886-92. 2009
    ....
  42. doi request reprint Acute granulomatous acanthamoeba encephalitis in an immunocompetent patient
    Peter Lackner
    Department of Neurology, Innsbruck Medical University, 6020 Innsbruck, Anichstrasse 35, Austria, Europe
    Neurocrit Care 12:91-4. 2010
    ..Acanthamoeba sp. are known to cause fatal granulomatous Acanthamoeba encephalitis (GAE) in immunocompromised patients...
  43. doi request reprint Efficacy of silver nanoparticles-impregnated external ventricular drain catheters in patients with acute occlusive hydrocephalus
    Peter Lackner
    Department of Neurology, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria
    Neurocrit Care 8:360-5. 2008
    ..The purpose of this pilot study was to address the efficacy of silver-impregnated EVD catheters in neurological and neurosurgical patients requiring external CSF drainage due to acute occlusive hydrocephalus...
  44. pmc Bi-insular cortical involvement in anti-NMDA-receptor encephalitis - a case report
    Harald Hegen
    Department of Neurology, Medical University of Innsbruck, Anichstrasse 35, A 6020, Innsbruck, Austria
    BMC Neurol 16:130. 2016
    ..Brain MRI is unremarkable in at least 50% of patients and highly variable in the remaining patients with signal abnormalities in different brain regions. Only scarce reports exist on other imaging modalities...
  45. ncbi request reprint Targeted Temperature Management in Spontaneous Intracerebral Hemorrhage: A Systematic Review
    Marlene Fischer
    Department of Neurology, Headache Outpatient Clinic, Medical University of Innsbruck, Austria
    Curr Drug Targets . 2016
    ..Single-center observational studies have shown reduced perihematomal edema under mild hypothermia and an association with favorable outcome. Thus, results from ongoing, prospective randomized-controlled trials are highly anticipated...
  46. doi request reprint Cerebral Taurine Levels are Associated with Brain Edema and Delayed Cerebral Infarction in Patients with Aneurysmal Subarachnoid Hemorrhage
    Mario Kofler
    Neurological Intensive Care Unit, Department of Neurology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria
    Neurocrit Care 23:321-9. 2015
    ..On the other hand, neuroprotective mechanisms of taurine treatment have been described in the experimental setting...
  47. doi request reprint Cooling Activity is Associated with Neurological Outcome in Patients with Severe Cerebrovascular Disease Undergoing Endovascular Temperature Control
    Marlene Fischer
    Neurocritical Care Unit, Department of Neurology, Medical University of Innsbruck, Anichstr 35, 6020, Innsbruck, Austria
    Neurocrit Care 23:205-9. 2015
    ..We analyzed the association between cooling activity expressed as cool bath temperatures and functional neurological outcome...
  48. pmc IgG-index predicts neurological morbidity in patients with infectious central nervous system diseases
    Peter Lackner
    Department of Neurology, Innsbruck Medical University, Austria
    BMC Infect Dis 10:202. 2010
    ..In this retrospective cross-sectional study the prognostic value of basic cerebrospinal fluid (CSF) parameters in patients with bacterial meningitis, viral meningoencephalitis and leptomeningeal metastases were evaluated...
  49. pmc Complement factors C1q, C3 and C5 in brain and serum of mice with cerebral malaria
    Peter Lackner
    Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    Malar J 7:207. 2008
    ..Immune-mediated and ischaemic mechanisms have been implicated. The role of complement factors C1q, C3 and C5 for the pathogenesis of CM were investigated in this study...
  50. doi request reprint Cerebral tau is elevated after aneurysmal subarachnoid haemorrhage and associated with brain metabolic distress and poor functional and cognitive long-term outcome
    Raimund Helbok
    Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    J Neurol Neurosurg Psychiatry 86:79-86. 2015
    ....
  51. doi request reprint Robot-assisted exercise for hand weakness after stroke: a pilot study
    Joel Stein
    Department of Rehabilitation and Regenerative Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Am J Phys Med Rehabil 90:887-94. 2011
    ..Few robotic devices have been available to provide therapy to the fingers and hand. This study was designed to test a new robotic device for hand rehabilitation in stroke survivors...
  52. doi request reprint Outcome prediction and temperature dependency of MR-proANP and Copeptin in comatose resuscitated patients
    Gregor Broessner
    Department of Neurology, Medical University of Innsbruck, Austria Electronic address
    Resuscitation 89:75-80. 2015
    ..To evaluate the prognostic potential of serum C-terminal provasopressin (CT-proAVP or Copeptin) and midregional pro-A-type natriuretic peptide (MR-proANP) to predict neurological outcome following resuscitation from cardiac arrest...
  53. pmc Mortality patterns and site heterogeneity of severe malaria in African children
    Eric Kendjo
    Medical Research Unit, Albert Schweitzer Hospital, Lambarene, Gabon
    PLoS ONE 8:e58686. 2013
    ..In this study we aimed to assess site heterogeneity of early, intermediate, and late mortality prediction in children with severe Plasmodium falciparum malaria in sub-Saharan Africa...
  54. pmc Scanning electron microscopy of the neuropathology of murine cerebral malaria
    Peter Lackner
    Clinical Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    Malar J 5:116. 2006
    ..The present study investigates the neuropathological features of murine CM by applying SEM...
  55. pmc Pharmacokinetics of intravenous linezolid in cerebrospinal fluid and plasma in neurointensive care patients with staphylococcal ventriculitis associated with external ventricular drains
    Ronny Beer
    Innsbruck Medical University, Clinical Department of Neurology, Neurological Intensive Care Unit, Anichstrasse 35, 6020 Innsbruck, Austria
    Antimicrob Agents Chemother 51:379-82. 2007
    ..9 mg x h/liter, with a CSF-to-plasma ratio of 0.8 +/- 0.3. Times above MIC in CSF were 99.8% and 57.2% for pathogens with MICs of 2 mg/liter and 4 mg/liter, respectively...
  56. pmc Nogo-A expression in the brain of mice with cerebral malaria
    Peter Lackner
    Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    PLoS ONE 6:e25728. 2011
    ..In the brain stem of severely affected animals increased Nogo-A expression and ultrastructural changes of the ER were observed. These data indicate a role of Nogo-A in neuronal stress response during experimental CM...
  57. pmc Takotsubo Cardiomyopathy in Traumatic Brain Injury
    Chun Fai Cheah
    Department of Neurology, Neurological Intensive Care Unit, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria
    Neurocrit Care . 2016
    ..Takotsubo cardiomyopathy (TC) is a well-known complication after aneurysmal subarachnoid hemorrhage and has been rarely described in patients with traumatic brain injury (TBI)...
  58. pmc Spreading depolarizations in patients with spontaneous intracerebral hemorrhage: Association with perihematomal edema progression
    Raimund Helbok
    Department of Neurology, Neurocritical Care Unit, Medical University Innsbruck, Austria
    J Cereb Blood Flow Metab . 2016
    ..Whether they may serve as target in the treatment of intracerebral hemorrhage deserves further research...
  59. doi request reprint Cerebral glucose hypometabolism in Tick-Borne Encephalitis, a pilot study in 10 Patients
    Anelia Dietmann
    Department of Neurology, Neurological Intensive Care Unit, Innsbruck Medical University, Innsbruck, Austria Electronic address
    Int J Infect Dis 51:73-77. 2016
    ..Brain metabolic changes related to radiologic and clinical findings have not been described so far...
  60. doi request reprint Can Therapeutic Hypothermia Be Guided by Advanced Neuromonitoring in Neurocritical Care Patients? A Review
    Alois Josef Schiefecker
    Division of Neurocritical Care, Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria
    Ther Hypothermia Temp Manag 5:126-34. 2015
    ..We call for more research using multimodal neuromonitoring techniques in patients undergoing TH to optimize cooling and rewarming strategies. ..
  61. doi request reprint The prognostic value of midregional proatrial natriuretic peptide in patients with hemorrhagic stroke
    Marlene Fischer
    Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    Cerebrovasc Dis 37:128-33. 2014
    ..This study aimed to analyze the prognostic value of MR-proANP in patients with hemorrhagic stroke, i.e. subarachnoid (SAH) and intracerebral hemorrhage (ICH)...
  62. doi request reprint Bedside use of a dual aortic balloon occlusion for the treatment of cerebral vasospasm
    Geoffrey Appelboom
    Department of Interventional Neuroradiology and Neurosurgery, Columbia University Medical Center, New York, NY, USA
    Neurocrit Care 13:385-8. 2010
    ..We report the first case of ultrasound-guided application of the NeuroFlo™ system at bedside in the Neurological Intensive Care Unit...
  63. ncbi request reprint Simplified multi-organ dysfunction score predicts disability in African children with Plasmodium falciparum malaria
    Raimund Helbok
    Clinical Department of Neurology, University of Innsbruck, Innsbruck, Austria
    Am J Trop Med Hyg 75:443-7. 2006
    ..The simplified MODS is a simple and sensitive measure merit of severity of illness in children with P. falciparum malaria and allows early prognostic evaluation...
  64. doi request reprint Rickettsiae, protozoa, and opisthokonta/metazoa
    Erich Schmutzhard
    Department of Neurology, Medical University Hospital Innsbruck, Innsbruck, Austria Electronic address
    Handb Clin Neurol 121:1403-43. 2014
    ....
  65. doi request reprint Chronic meningitis
    Raimund Helbok
    Dept of Neurology, Medical University Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria
    J Neurol 256:168-75. 2009
    ..However, most patients with idiopathic chronic meningitis have a relatively good outcome...
  66. pmc Remote ischemic preconditioning in the prevention of ischemic brain damage during intracranial aneurysm treatment (RIPAT): study protocol for a randomized controlled trial
    Selma Tülü
    Department of Neurosurgery, Medical University of Innsbruck, 35, Anichstrasse, Innsbruck, 6020, Austria
    Trials 16:594. 2015
    ..We hypothesize that pre-interventional remote ischemic preconditioning (RIPC) reduces ischemic cerebral tissue damage in patients undergoing elective intracranial aneurysm treatment...
  67. doi request reprint Breath analysis for in vivo detection of pathogens related to ventilator-associated pneumonia in intensive care patients: a prospective pilot study
    Wojciech Filipiak
    Breath Research Institute of the Leopold Franzens University of Innsbruck, Rathausplatz 4, A 6850 Dornbirn, Austria Innsbruck Medical University, Anichstraße 35, A 6020 Innsbruck, Austria
    J Breath Res 9:016004. 2015
    ....
  68. pmc Severe malaria in children leads to a significant impairment of transitory otoacoustic emissions--a prospective multicenter cohort study
    Joachim Schmutzhard
    Department of Otorhinolaryngology, Medical University Innsbruck, Anichstrasse 35, A 6020, Innsbruck, Austria
    BMC Med 13:125. 2015
    ..An objective method to quickly evaluate the function of the inner ear are the otoacoustic emissions. Negative transient otoacoustic emissions are associated with a threshold shift of 20 dB and above...
  69. doi request reprint A pilot study of robotic-assisted exercise for hand weakness after stroke
    Joel Stein
    Department of Rehabilitation and Regenerative Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA
    IEEE Int Conf Rehabil Robot 2011:5975426. 2011
    ..We conclude that robotic therapy for hand paresis after stroke is safe and feasible, and that further studies of efficacy are justified by these preliminary results...
  70. doi request reprint In-hospital risk estimation in children with malaria--early predictors of morbidity and mortality
    Andrea Sylvia Winkler
    Department of Neurology, University of Ulm, Ulm, Germany
    J Trop Pediatr 54:184-91. 2008
    ..A reliable but easy system for disease severity assessment would help to fast track seriously ill children and provide suitable therapies for different patient groups...