Soheyl Bahrami

Summary

Country: Austria

Publications

  1. doi request reprint Circulating NT-proCNP predicts sepsis in multiple-traumatized patients without traumatic brain injury
    Soheyl Bahrami
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Research Centre of AUVA, Vienna, Austria
    Crit Care Med 38:161-6. 2010
  2. doi request reprint Xylazine-/diazepam-ketamine and isoflurane differentially affect hemodynamics and organ injury under hemorrhagic/traumatic shock and resuscitation in rats
    Soheyl Bahrami
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology in the Research Center of AUVA, Vienna, Austria
    Shock 35:573-8. 2011
  3. ncbi request reprint Release and hemodynamic influence of nitro-glycerine-derived nitric oxide in endotoxemic rats
    Andrey V Kozlov
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Donaueschingenstr 13, A 1200 Vienna, Austria
    Vascul Pharmacol 43:411-4. 2005
  4. pmc Relationship between age/gender-induced survival changes and the magnitude of inflammatory activation and organ dysfunction in post-traumatic sepsis
    Susanne Drechsler
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology in the Trauma Research Center of Allgemeine Unfallversicherungsanstalt, Vienna, Austria
    PLoS ONE 7:e51457. 2012
  5. ncbi request reprint Different effects of endotoxic shock on the respiratory function of liver and heart mitochondria in rats
    Andrey V Kozlov
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Donaueschingenstrasse 13, A 1200 Vienna, Austria
    Am J Physiol Gastrointest Liver Physiol 290:G543-9. 2006
  6. ncbi request reprint Skeletal muscles, heart, and lung are the main sources of oxygen radicals in old rats
    Andrey V Kozlov
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria
    Biochim Biophys Acta 1740:382-9. 2005
  7. doi request reprint Peritoneal inflammation in pigs is associated with early mitochondrial dysfunction in liver and kidney
    Andrey V Kozlov
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, AUVA Research Center, 1200, Vienna, Austria
    Inflammation 33:295-305. 2010
  8. ncbi request reprint Epr analysis reveals three tissues responding to endotoxin by increased formation of reactive oxygen and nitrogen species
    Andrey V Kozlov
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria
    Free Radic Biol Med 34:1555-62. 2003
  9. pmc A non-lethal traumatic/hemorrhagic insult strongly modulates the compartment-specific PAI-1 response in the subsequent polymicrobial sepsis
    Pierre Raeven
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Trauma Research Center of Allgemeine Unfallversicherungsanstalt, Vienna, Austria
    PLoS ONE 8:e55467. 2013
  10. ncbi request reprint Neuron-specific-enolase is increased in plasma after hemorrhagic shock and after bilateral femur fracture without traumatic brain injury in the rat
    Linda E Pelinka
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology and Research Center of the Worker s Compensation Board AUVA, Vienna, Austria
    Shock 22:88-91. 2004

Collaborators

Detail Information

Publications32

  1. doi request reprint Circulating NT-proCNP predicts sepsis in multiple-traumatized patients without traumatic brain injury
    Soheyl Bahrami
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Research Centre of AUVA, Vienna, Austria
    Crit Care Med 38:161-6. 2010
    ....
  2. doi request reprint Xylazine-/diazepam-ketamine and isoflurane differentially affect hemodynamics and organ injury under hemorrhagic/traumatic shock and resuscitation in rats
    Soheyl Bahrami
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology in the Research Center of AUVA, Vienna, Austria
    Shock 35:573-8. 2011
    ..Anesthetics differentially affect HTS-induced hemodynamic alterations and organ injury. Thus, when interpreting data from HTS models, the individual effect of anesthetics should be considered...
  3. ncbi request reprint Release and hemodynamic influence of nitro-glycerine-derived nitric oxide in endotoxemic rats
    Andrey V Kozlov
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Donaueschingenstr 13, A 1200 Vienna, Austria
    Vascul Pharmacol 43:411-4. 2005
    ....
  4. pmc Relationship between age/gender-induced survival changes and the magnitude of inflammatory activation and organ dysfunction in post-traumatic sepsis
    Susanne Drechsler
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology in the Trauma Research Center of Allgemeine Unfallversicherungsanstalt, Vienna, Austria
    PLoS ONE 7:e51457. 2012
    ....
  5. ncbi request reprint Different effects of endotoxic shock on the respiratory function of liver and heart mitochondria in rats
    Andrey V Kozlov
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Donaueschingenstrasse 13, A 1200 Vienna, Austria
    Am J Physiol Gastrointest Liver Physiol 290:G543-9. 2006
    ....
  6. ncbi request reprint Skeletal muscles, heart, and lung are the main sources of oxygen radicals in old rats
    Andrey V Kozlov
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria
    Biochim Biophys Acta 1740:382-9. 2005
    ..This study identifies heart, lung, and skeletal muscle as the tissues with increased RONS formation as a function of age...
  7. doi request reprint Peritoneal inflammation in pigs is associated with early mitochondrial dysfunction in liver and kidney
    Andrey V Kozlov
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, AUVA Research Center, 1200, Vienna, Austria
    Inflammation 33:295-305. 2010
    ..We did not find proof that mitochondrial dysfunction was due to increased levels of either nitric oxide (NO) or products of HO, but it was accompanied by increased levels of oxidative stress markers...
  8. ncbi request reprint Epr analysis reveals three tissues responding to endotoxin by increased formation of reactive oxygen and nitrogen species
    Andrey V Kozlov
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria
    Free Radic Biol Med 34:1555-62. 2003
    ..In summary, low-temperature EPR combined with CP-H infusion allowed detection of local RONS formation in tissues. Increased formation of RONS in response to endotoxin challenge is organ specific...
  9. pmc A non-lethal traumatic/hemorrhagic insult strongly modulates the compartment-specific PAI-1 response in the subsequent polymicrobial sepsis
    Pierre Raeven
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Trauma Research Center of Allgemeine Unfallversicherungsanstalt, Vienna, Austria
    PLoS ONE 8:e55467. 2013
    ..We examined how trauma-hemorrhage (TH) modulates PAI-1 responses in subsequent cecal ligation and puncture (CLP)-induced sepsis, and the association of PAI-1 with septic outcomes...
  10. ncbi request reprint Neuron-specific-enolase is increased in plasma after hemorrhagic shock and after bilateral femur fracture without traumatic brain injury in the rat
    Linda E Pelinka
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology and Research Center of the Worker s Compensation Board AUVA, Vienna, Austria
    Shock 22:88-91. 2004
    ..From a clinical point of view, these findings indicate that NSE cannot be considered a reliable marker of traumatic brain injury early after trauma in cases associated with hemorrhagic shock and/or femur fracture...
  11. ncbi request reprint Nonspecific increase of systemic neuron-specific enolase after trauma: clinical and experimental findings
    Linda E Pelinka
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology at the Research Centre of the Allgemeine Unfallversicherungsanstalt, A 1200, Vienna, Austria
    Shock 24:119-23. 2005
    ..005), and kidney (P < 0.0005). Our data show that systemic NSE increases to similar degrees with and without TBI. Therefore, NSE is not a useful early marker of TBI in multiple trauma...
  12. ncbi request reprint Release of S100B differs during ischemia and reperfusion of the liver, the gut, and the kidney in rats
    Linda E Pelinka
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology and Research Center of the Allgemeine Unfallversicherungsanstalt AUVA, Vienna, Austria
    Shock 21:72-6. 2004
    ....
  13. doi request reprint Rons formation under restrictive reperfusion does not affect organ dysfunction early after hemorrhage and trauma
    Clara Zifko
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology in AUVA Research Center, Vienna, Austria
    Shock 34:384-9. 2010
    ..Moreover, scavenging of RONS does not affect the early organ dysfunction manifested at the end of a phase of restrictive reperfusion...
  14. doi request reprint Thromboelastometric (ROTEM) findings in patients suffering from isolated severe traumatic brain injury
    Herbert Schöchl
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology and AUVA Research Centre, Vienna, Austria
    J Neurotrauma 28:2033-41. 2011
    ..ROTEM testing appeared to offer an early signal of severe life-threatening sTBI. Further studies are warranted to confirm these results and to investigate the role of ROTEM in guiding coagulation therapy...
  15. ncbi request reprint Hemorrhage- and resuscitation-related alterations in gastrointestinal circulation: effect of a low dose of L-NMMA
    Babak Sobhian
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology Donaueschingenstrasse 13, A 1200, Vienna, Austria
    Shock 23:243-7. 2005
    ....
  16. doi request reprint Transient increase of free iron in rat livers following hemorrhagic-traumatic shock and reperfusion is independent of heme oxygenase 1 upregulation
    Astrid Postl
    Department of Biomedical Sciences, University of Veterinary Medicine, Veterinaerplatz 1, Vienna, Austria
    Shock 36:501-9. 2011
    ..Thus, upregulation of HO activity by hemin does not increase Fe2+ levels following HTS and reperfusion...
  17. doi request reprint Compartment-specific expression of plasminogen activator inhibitor-1 correlates with severity/outcome of murine polymicrobial sepsis
    Pierre Raeven
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology in the Trauma Research Center of the AUVA, Vienna, Austria
    Thromb Res 129:e238-45. 2012
    ..We aimed to characterize spatiotemporal PAI-1 gene/protein changes occurring in acute sepsis and tested whether PAI-1 fluctuations correlate with sepsis severity and early outcome...
  18. doi request reprint Similarities in thromboelastometric (ROTEM®) findings between humans and baboons
    Herbert Schöchl
    Ludwig Boltzmann Institute of Experimental and Clinical Traumatology, Vienna, Austria
    Thromb Res 130:e107-12. 2012
    ..Interest in visco-elastic testing in different clinical scenarios has increased but few data are available on thromboelastometric findings in primates...
  19. doi request reprint Nitric oxide-supplemented resuscitation improves early gastrointestinal blood flow in rats subjected to hemorrhagic shock without late consequences
    Babak Sobhian
    Ludwig Boltzmann Institute of Experimental and Clinical Traumatology and Research Center of the Allgemeine Unfallversicherungsanstalt, Donaueschingenstr 13, A 1200, Vienna, Austria
    Am J Surg 201:100-10. 2011
    ..This study aimed to determine the effect of nitric oxide (NO) supplemented resuscitation on the mean arterial blood pressure (MAP), GI-BF, and outcome after hemorrhagic shock...
  20. pmc Thromboelastometry (TEM) findings in disseminated intravascular coagulation in a pig model of endotoxinemia
    Herbert Schöchl
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria
    Mol Med 17:266-72. 2011
    ..Further investigations are necessary to establish the clinical relevance of these findings...
  21. ncbi request reprint Small-volume fluid resuscitation with hypertonic saline prevents inflammation but not mortality in a rat model of hemorrhagic shock
    Soheyl Bahrami
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Donaueschingenstrasse 13, A 1200, Vienna, Austria
    Shock 25:283-9. 2006
    ..63%, respectively). In summary, hypotensive resuscitation with hypertonic fluids reduces the inflammatory response but not lung tissue damage or mortality after severe hemorrhagic shock...
  22. ncbi request reprint Large animal models: baboons for trauma, shock, and sepsis studies
    Heinz Redl
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, A 1200 Vienna, Austria
    Shock 24:88-93. 2005
    ....
  23. doi request reprint Repetitive low-volume blood sampling method as a feasible monitoring tool in a mouse model of sepsis
    Katrin M Weixelbaumer
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology in the Trauma Research Center of AUVA, Vienna, Austria
    Shock 34:420-6. 2010
    ..9; slope, ≥0.9), except lymphocytes (r > 0.5; slope, >0.5). This method provides a feasible and safe translation of clinically relevant daily immunomonitoring to the mouse sepsis model...
  24. doi request reprint The matricellular "cysteine-rich protein 61" is released from activated platelets and increased in the circulation during experimentally induced sepsis
    Claus Vinter B Hviid
    Institute for Surgical Research, Oslo University Hospital HF Rikshospitalet Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway and Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria
    Shock 41:233-40. 2014
    ..It provides evidence that CCN1 is released from activated platelets, suggesting that platelets constitute a novel source for CCN1 release to the circulation during sepsis. ..
  25. doi request reprint Mouse model of posttraumatic abdominal sepsis: survival advantage of females over males does not depend on the cecum size
    Paul Wehrenpfennig
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, AUVA Research Center, Vienna, Austria
    Eur Surg Res 52:83-9. 2014
    ..Comparing two ligation approaches, we investigated whether cecum size influences gender-specific outcome differences...
  26. doi request reprint Estrus cycle status defined by vaginal cytology does not correspond to fluctuations of circulating estrogens in female mice
    Katrin M Weixelbaumer
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology in AUVA Research Center Department of Biomedical Sciences, Bioinformatics and Biostatistics Platform and Department of Biomedical Sciences, Institute of Medical Biochemistry University of Veterinary Medicine, Vienna, Austria
    Shock 41:145-53. 2014
    ..The flaws and advantages of the examined monitoring methods should be considered in the design of future shock studies. ..
  27. doi request reprint Increased circulating D-lactate levels predict risk of mortality after hemorrhage and surgical trauma in baboons
    Babak Sobhian
    Ludwig Boltzmann Institute of Experimental and Clinical Traumatology, Research Center of the AUVA, Vienna, Austria
    Shock 37:473-7. 2012
    ..34 μg/mL produced sensitivity of 73% to 99% and specificity of 50% to 83%. Our data suggest that elevation of plasma D-lactate after 24 h predicts an increased risk of mortality after hemorrhage and trauma...
  28. ncbi request reprint Lipopolysaccharide dose response in baboons
    Sandra B Haudek
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria
    Shock 20:431-6. 2003
    ....
  29. pmc Mitochondrial dysfunction and biogenesis: do ICU patients die from mitochondrial failure?
    Andrey V Kozlov
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, AUVA Research Center, A 1200 Vienna, Austria
    Ann Intensive Care 1:41. 2011
    ..Collectively the data discussed in this review suggest that appropriate diagnosis and specific treatment of mitochondrial dysfunction in ICU patients may significantly improve the clinical outcome...
  30. ncbi request reprint Nitric oxide synthase inhibitors affect nitric oxide synthesis in normoxic but not in ischemic organs during intestinal ischemia and early reperfusion
    Andrey V Kozlov
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, University of Veterinary Medicine, Vienna, Austria
    J Lab Clin Med 140:303-11. 2002
    ..The protective effect of L-arginine supplementation during I/R(i) is probably related to increasing intravascular NO formation...
  31. ncbi request reprint A 4-amino analogue of tetrahydrobiopterin attenuates endotoxin-induced hemodynamic alterations and organ injury in rats
    Florian Fitzal
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria
    Shock 18:158-62. 2002
    ..This may, at least in part, account for the previously observed protection of rats by 4-ABH4 against endotoxin-induced mortality in the same endotoxic shock model...
  32. ncbi request reprint Hemorrhagic shock induces an S 100 B increase associated with shock severity
    Linda E Pelinka
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology and Research Center of the Allgemeine Unfallversicherungsanstalt, Vienna, Austria
    Shock 19:422-6. 2003
    ..The data presented demonstrate for the first time that the S 100 B increase is induced by hemorrhagic shock and is associated with the severity of shock...