David E L Wilcken

Summary

Affiliation: University of New South Wales
Country: Australia

Publications

  1. ncbi request reprint B vitamins and homocysteine in cardiovascular disease and aging
    D E Wilcken
    Department of Cardiovascular Medicine, University of New South Wales, Prince Henry Hospital, Sydney
    Ann N Y Acad Sci 854:361-70. 1998
  2. ncbi request reprint Relationship between homocysteine and superoxide dismutase in homocystinuria: possible relevance to cardiovascular risk
    D E Wilcken
    Department of Cardiovascular Medicine, Prince of Wales Hospital, Sydney, Australia
    Arterioscler Thromb Vasc Biol 20:1199-202. 2000
  3. ncbi request reprint Asymmetric dimethylarginine (ADMA) in vascular, renal and hepatic disease and the regulatory role of L-arginine on its metabolism
    David E L Wilcken
    Department of Cardiovascular Medicine, The University of New South Wales and the Prince of Wales Hospital, Sydney, Australia
    Mol Genet Metab 91:309-17; discussion 308. 2007
  4. ncbi request reprint Obesity, Type II diabetes and the Ala54Thr polymorphism of fatty acid binding protein 2 in the Tongan population
    Natalia L Duarte
    Cardiovascular Genetics Laboratory, Department of Medicine, Prince of Wales Hospital and the University of New South Wales, Sydney, NSW 2031, Australia
    Mol Genet Metab 79:183-8. 2003
  5. ncbi request reprint A 45-bp insertion/deletion polymorphism of uncoupling protein 2 in relation to obesity in Tongans
    Natalia L Duarte
    Cardiovascular Genetics Laboratory, Department of Medicine, Prince of Wales Hospital, University of New South Wales, Sydney, Australia
    Obes Res 11:512-7. 2003
  6. ncbi request reprint Relations between markers of renal function, coronary risk factors and the occurrence and severity of coronary artery disease
    Jun Wang
    Department of Cardiovascular Medicine, University of New South Wales, Prince of Wales Hospital, Sydney, Australia
    Atherosclerosis 197:853-9. 2008
  7. ncbi request reprint Relations between plasma asymmetric dimethylarginine (ADMA) and risk factors for coronary disease
    Jun Wang
    Department of Cardiovascular Medicine, University of New South Wales, Prince of Wales Hospital, Sydney, Australia
    Atherosclerosis 184:383-8. 2006
  8. ncbi request reprint Effect of CYP1A1 MspI polymorphism on cigarette smoking related coronary artery disease and diabetes
    Xing Li Wang
    Cardiovascular Genetics Laboratory, Eastern Heart Clinic, Center of Thrombosis and Vascular Research, University of New South Wales, Sydney, Australia
    Atherosclerosis 162:391-7. 2002
  9. ncbi request reprint Asymmetric dimethylarginine in homocystinuria due to cystathionine beta-synthase deficiency: relevance of renal function
    David E L Wilcken
    University of New South Wales, Sydney, Australia
    J Inherit Metab Dis 29:30-7. 2006
  10. ncbi request reprint Obesity, Type II diabetes and the beta 2 adrenoceptor gene Gln27Glu polymorphism in the Tongan population
    Natalia L Duarte
    Cardiovascular Genetics Laboratory, Department of Medicine, Prince of Wales Hospital and the University of New South Wales, Sydney, New South Wales 2031, Australia
    Clin Sci (Lond) 104:211-5. 2003

Collaborators

Detail Information

Publications14

  1. ncbi request reprint B vitamins and homocysteine in cardiovascular disease and aging
    D E Wilcken
    Department of Cardiovascular Medicine, University of New South Wales, Prince Henry Hospital, Sydney
    Ann N Y Acad Sci 854:361-70. 1998
    ....
  2. ncbi request reprint Relationship between homocysteine and superoxide dismutase in homocystinuria: possible relevance to cardiovascular risk
    D E Wilcken
    Department of Cardiovascular Medicine, Prince of Wales Hospital, Sydney, Australia
    Arterioscler Thromb Vasc Biol 20:1199-202. 2000
    ..EC-SOD levels may be relevant to the pathogenesis of vascular disease in other patient groups...
  3. ncbi request reprint Asymmetric dimethylarginine (ADMA) in vascular, renal and hepatic disease and the regulatory role of L-arginine on its metabolism
    David E L Wilcken
    Department of Cardiovascular Medicine, The University of New South Wales and the Prince of Wales Hospital, Sydney, Australia
    Mol Genet Metab 91:309-17; discussion 308. 2007
    ..This paper also reviews associations between the metabolism of ADMA and insulin resistance, smoking and homocysteine which are all associated with an increased risk of vascular disease...
  4. ncbi request reprint Obesity, Type II diabetes and the Ala54Thr polymorphism of fatty acid binding protein 2 in the Tongan population
    Natalia L Duarte
    Cardiovascular Genetics Laboratory, Department of Medicine, Prince of Wales Hospital and the University of New South Wales, Sydney, NSW 2031, Australia
    Mol Genet Metab 79:183-8. 2003
    ..We conclude that there is a high prevalence of the FABP2 Ala54Thr polymorphism in Tongans. The polymorphism may be involved in lipid metabolism as the Thr allele is associated with low total and LDL cholesterol levels in this population...
  5. ncbi request reprint A 45-bp insertion/deletion polymorphism of uncoupling protein 2 in relation to obesity in Tongans
    Natalia L Duarte
    Cardiovascular Genetics Laboratory, Department of Medicine, Prince of Wales Hospital, University of New South Wales, Sydney, Australia
    Obes Res 11:512-7. 2003
    ..This may be the result of a founder effect and may be relevant to the prevalence of obesity and type 2 diabetes in Tonga...
  6. ncbi request reprint Relations between markers of renal function, coronary risk factors and the occurrence and severity of coronary artery disease
    Jun Wang
    Department of Cardiovascular Medicine, University of New South Wales, Prince of Wales Hospital, Sydney, Australia
    Atherosclerosis 197:853-9. 2008
    ..To explore this we assessed relations between measures of mild impairment of renal function and coronary artery disease (CAD) together with other risk factors...
  7. ncbi request reprint Relations between plasma asymmetric dimethylarginine (ADMA) and risk factors for coronary disease
    Jun Wang
    Department of Cardiovascular Medicine, University of New South Wales, Prince of Wales Hospital, Sydney, Australia
    Atherosclerosis 184:383-8. 2006
    ..Elevated plasma levels of asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide production, are reported to be associated with coronary artery disease (CAD)...
  8. ncbi request reprint Effect of CYP1A1 MspI polymorphism on cigarette smoking related coronary artery disease and diabetes
    Xing Li Wang
    Cardiovascular Genetics Laboratory, Eastern Heart Clinic, Center of Thrombosis and Vascular Research, University of New South Wales, Sydney, Australia
    Atherosclerosis 162:391-7. 2002
    ..The presence of the rare C allele of the CYP1A1 gene in smokers may enhance predisposition to severe CAD and type 2 diabetes. These findings contribute to the understanding of cardiovascular risk and to smoking related vascular disease...
  9. ncbi request reprint Asymmetric dimethylarginine in homocystinuria due to cystathionine beta-synthase deficiency: relevance of renal function
    David E L Wilcken
    University of New South Wales, Sydney, Australia
    J Inherit Metab Dis 29:30-7. 2006
    ..We investigated whether ADMA levels are elevated in CBS patients with and without renal impairment, and whether lowering plasma homocysteine also lowers ADMA...
  10. ncbi request reprint Obesity, Type II diabetes and the beta 2 adrenoceptor gene Gln27Glu polymorphism in the Tongan population
    Natalia L Duarte
    Cardiovascular Genetics Laboratory, Department of Medicine, Prince of Wales Hospital and the University of New South Wales, Sydney, New South Wales 2031, Australia
    Clin Sci (Lond) 104:211-5. 2003
    ....
  11. ncbi request reprint Homocysteine as a risk factor for cognitive impairment in stroke patients
    Perminder S Sachdev
    School of Psychiatry, University of New South Wales, Prince of Wales Hospital, Sydney, Australia
    Dement Geriatr Cogn Disord 15:155-62. 2003
    ..Elevated total homocysteine (tHcy) levels are associated with an increased risk of cerebrovascular disease. It is uncertain whether tHcy is also an independent risk factor for cognitive impairment...
  12. ncbi request reprint Glutathione S-transferase mu1 deficiency, cigarette smoking and coronary artery disease
    Xing Li Wang
    Cardiovascular Genetics Laboratory, Eastern Heart Clinic, and Center of Thrombosis and Vascular Research, University of New South Wales, Sydney, Australia
    J Cardiovasc Risk 9:25-31. 2002
    ..In the present study we explored the hypothesis that GSTM1 deficiency, caused by GSTM1 null allele, may predispose subjects to cigarette smoking related CAD risk...
  13. pmc Diversity of cystathionine beta-synthase haplotypes bearing the most common homocystinuria mutation c.833T>C: a possible role for gene conversion
    Petr Vyletal
    Center for Applied Genomics, Institute of Inherited Metabolic Disorders, Charles University 1st Faculty of Medicine, Prague, Czech Republic
    Hum Mutat 28:255-64. 2007
    ..833C; -] chromosomes may have originated by recurrent gene conversion employing the common nonpathogenic c.[833C; 844_845ins68] chromosomes as templates...
  14. ncbi request reprint The p53Pro72Arg polymorphism is associated with albuminuria among aboriginal Australians
    Stephen P McDonald
    Menzies School of Health Research, Darwin, Australia
    J Am Soc Nephrol 13:677-83. 2002
    ....