R J Vandenberg

Summary

Affiliation: University of Sydney
Country: Australia

Publications

  1. ncbi request reprint How and why are channels in transporters?
    Robert J Vandenberg
    Department of Pharmacology, Institute for Biomedical Research, University of Sydney, Sydney, NSW, 2006 Australia
    Sci STKE 2005:pe17. 2005
  2. ncbi request reprint Allosteric modulation of neurotransmitter transporters at excitatory synapses
    Robert J Vandenberg
    Department of Pharmacology, Institute for Biomedical Research, University of Sydney, Sydney 2006, NSW, Australia
    Eur J Pharm Sci 23:1-11. 2004
  3. ncbi request reprint Slips, leaks and channels in glutamate transporters
    Robert J Vandenberg
    Discipline of Pharmacology, School of Medical Sciences, Bosch Institute, University of Sydney, Sydney, Australia
    Channels (Austin) 2:51-8. 2008
  4. ncbi request reprint Mutational analysis of glutamate transporters
    R J Vandenberg
    Department of Pharmacology, Institute for Biomedical Research, University of Sydney, 2006 New South Wales, Australia
    Handb Exp Pharmacol . 2006
  5. ncbi request reprint Contrasting modes of action of methylglutamate derivatives on the excitatory amino acid transporters, EAAT1 and EAAT2
    R J Vandenberg
    Department of Pharmacology, University of Sydney, New South Wales, Australia
    Mol Pharmacol 51:809-15. 1997
  6. ncbi request reprint Molecular basis for differential inhibition of glutamate transporter subtypes by zinc ions
    R J Vandenberg
    Department of Pharmacology, The University of Sydney, Sydney, New South Wales 2006, Australia
    Mol Pharmacol 54:189-96. 1998
  7. ncbi request reprint Zn(2+) inhibits the anion conductance of the glutamate transporter EEAT4
    A D Mitrovic
    Department of Pharmacology, University of Sydney, New South Wales, 2006, Australia
    J Biol Chem 276:26071-6. 2001
  8. pmc N[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine (NFPS) is a selective persistent inhibitor of glycine transport
    K R Aubrey
    Department of Pharmacology, University of Sydney, NSW, 2006, Australia
    Br J Pharmacol 134:1429-36. 2001
  9. pmc Oleoyl-L-carnitine inhibits glycine transport by GlyT2
    J E Carland
    Discipline of Pharmacology, School of Medical Sciences, Bosch Institute, Sydney Medical School, University of Sydney, Sydney, NSW, Australia
    Br J Pharmacol 168:891-902. 2013
  10. pmc Analogues of gamma-aminobutyric acid (GABA) and trans-4-aminocrotonic acid (TACA) substituted in the 2 position as GABAC receptor antagonists
    M Chebib
    Adrien Albert Laboratory of Medicinal Chemistry, Department of Pharmacology, University of Sydney, NSW, Australia
    Br J Pharmacol 122:1551-60. 1997

Collaborators

Detail Information

Publications13

  1. ncbi request reprint How and why are channels in transporters?
    Robert J Vandenberg
    Department of Pharmacology, Institute for Biomedical Research, University of Sydney, Sydney, NSW, 2006 Australia
    Sci STKE 2005:pe17. 2005
    ..However, neurotransmitter transporters can be both. Vandenberg and Ryan discuss recent developments in understanding how and why these transporters contain ion channels...
  2. ncbi request reprint Allosteric modulation of neurotransmitter transporters at excitatory synapses
    Robert J Vandenberg
    Department of Pharmacology, Institute for Biomedical Research, University of Sydney, Sydney 2006, NSW, Australia
    Eur J Pharm Sci 23:1-11. 2004
    ..We shall discuss how the activity of one such compound may be expected to influence excitatory neurotransmission...
  3. ncbi request reprint Slips, leaks and channels in glutamate transporters
    Robert J Vandenberg
    Discipline of Pharmacology, School of Medical Sciences, Bosch Institute, University of Sydney, Sydney, Australia
    Channels (Austin) 2:51-8. 2008
    ..We will also discuss some of the alternate conducting states of glutamate transporters and provide definitions of the various states...
  4. ncbi request reprint Mutational analysis of glutamate transporters
    R J Vandenberg
    Department of Pharmacology, Institute for Biomedical Research, University of Sydney, 2006 New South Wales, Australia
    Handb Exp Pharmacol . 2006
    ....
  5. ncbi request reprint Contrasting modes of action of methylglutamate derivatives on the excitatory amino acid transporters, EAAT1 and EAAT2
    R J Vandenberg
    Department of Pharmacology, University of Sydney, New South Wales, Australia
    Mol Pharmacol 51:809-15. 1997
    ....
  6. ncbi request reprint Molecular basis for differential inhibition of glutamate transporter subtypes by zinc ions
    R J Vandenberg
    Department of Pharmacology, The University of Sydney, Sydney, New South Wales 2006, Australia
    Mol Pharmacol 54:189-96. 1998
    ..Mutation of this glycine residue in EAAT2 to histidine generates a Zn2+ sensitive transporter, further confirming the role of this residue in conferring differential Zn2+ sensitivity...
  7. ncbi request reprint Zn(2+) inhibits the anion conductance of the glutamate transporter EEAT4
    A D Mitrovic
    Department of Pharmacology, University of Sydney, New South Wales, 2006, Australia
    J Biol Chem 276:26071-6. 2001
    ..Two histidine residues in the extracellular loop between transmembrane domains three and four of EAAT4 appear to confer Zn(2+) inhibition of the anion conductance...
  8. pmc N[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine (NFPS) is a selective persistent inhibitor of glycine transport
    K R Aubrey
    Department of Pharmacology, University of Sydney, NSW, 2006, Australia
    Br J Pharmacol 134:1429-36. 2001
    ..NFPS inhibition of glycine transport is time and concentration dependent and inhibition of transport by NFPS persists after washout of NFPS from the bath solution, which suggests that inhibition by NFPS is long lasting...
  9. pmc Oleoyl-L-carnitine inhibits glycine transport by GlyT2
    J E Carland
    Discipline of Pharmacology, School of Medical Sciences, Bosch Institute, Sydney Medical School, University of Sydney, Sydney, NSW, Australia
    Br J Pharmacol 168:891-902. 2013
    ..We have assessed a series of endogenous lipids as inhibitors of GlyT1 and GlyT2...
  10. pmc Analogues of gamma-aminobutyric acid (GABA) and trans-4-aminocrotonic acid (TACA) substituted in the 2 position as GABAC receptor antagonists
    M Chebib
    Adrien Albert Laboratory of Medicinal Chemistry, Department of Pharmacology, University of Sydney, NSW, Australia
    Br J Pharmacol 122:1551-60. 1997
    ..It is suggested that only compounds that can attain relatively flat conformations may bind to the GABAC receptor agonist/competitive antagonist binding site...
  11. ncbi request reprint Unsaturated phosphinic analogues of gamma-aminobutyric acid as GABA(C) receptor antagonists
    M Chebib
    Department of Pharmacology, The University of Sydney, NSW, Australia
    Eur J Pharmacol 329:223-9. 1997
    ..This order of potency differs from that reported for these compounds as GABA(B) receptor agonists, where the phosphinic acids are more potent than the corresponding methylphosphinic acids...
  12. pmc Niflumic acid modulates uncoupled substrate-gated conductances in the human glutamate transporter EAAT4
    M V Poulsen
    Department of Pharmacology D06, University of Sydney, Sydney, NSW 2006, Australia
    J Physiol 534:159-67. 2001
    ....
  13. ncbi request reprint Molecular pharmacology and physiology of glutamate transporters in the central nervous system
    R J Vandenberg
    Department of Pharmacology, University of Sydney, New South Wales, Australia
    Clin Exp Pharmacol Physiol 25:393-400. 1998
    ....