Lukas P Staub
Affiliation: University of Sydney
- Linking the evidence: intermediate outcomes in medical test assessmentsLukas P Staub
The University of Sydney
Int J Technol Assess Health Care 28:52-8. 2012..The aim of this study is to review how health technology assessments (HTA) of medical tests incorporate intermediate outcomes in conclusions about the effectiveness of tests on improving health outcomes...
- Using patient management as a surrogate for patient health outcomes in diagnostic test evaluationLukas P Staub
NHMRC Clinical Trials Centre, The University of Sydney, Sydney, Australia
BMC Med Res Methodol 12:12. 2012..There is a lack of guidance on the interpretation of this evidence, and patient management studies often neglect a discussion of the limitations of measuring patient management as a surrogate for health outcomes...
- Does point of care prothrombin time measurement reduce the transfusion of fresh frozen plasma in patients undergoing major surgery? The POC-OP randomized-controlled trialNatalie Urwyler
University Department of Anesthesiology and Pain Therapy, University Hospital of Bern, Inselspital, 3010 Bern, Switzerland
Trials 10:107. 2009..It is fast, easy to perform, inexpensive and may enable physicians to rationally determine the need for FFP...
- Clinical validation study to measure the performance of the Nerve Root Sedimentation Sign for the diagnosis of lumbar spinal stenosisLukas P Staub
NHMRC Clinical Trials Centre, University of Sydney, Camperdown NSW 1450, Australia
Contemp Clin Trials 32:470-4. 2011..The observed proportion of discordant test results will help inform the design of future randomised controlled trials of the Sedimentation Sign...