Allison R Pettit

Summary

Affiliation: University of Queensland
Country: Australia

Publications

  1. doi request reprint Osteal macrophages: a new twist on coupling during bone dynamics
    Allison R Pettit
    The University of Queensland, Institute for Molecular Bioscience, Cooperative Research Centre for Chronic Inflammatory Diseases, Brisbane, QLD 4072, Australia
    Bone 43:976-82. 2008
  2. doi request reprint Osteal macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model
    Kylie A Alexander
    The University of Queensland, UQ Centre for Clinical Research, Herston, Australia
    J Bone Miner Res 26:1517-32. 2011
  3. doi request reprint Absence of B cells does not compromise intramembranous bone formation during healing in a tibial injury model
    Liza J Raggatt
    University of Queensland Centre for Clinical Research, The University of Queensland, Herston, Brisbane, Australia
    Am J Pathol 182:1501-8. 2013
  4. ncbi request reprint Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and in vivo
    Ming K Chang
    Institute for Molecular Bioscience, Cooperative Research Centre for Chronic Inflammatory Diseases, University of Queensland, Brisbane, Queensland, Australia
    J Immunol 181:1232-44. 2008
  5. doi request reprint Soluble lymphotoxin is an important effector molecule in GVHD and GVL
    Kate A Markey
    Queensland Institute of Medical Research, Brisbane, Australia
    Blood 115:122-32. 2010
  6. doi request reprint An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation
    Kelli P A MacDonald
    Queensland Institute of Medical Research, Brisbane, Australia
    Blood 116:3955-63. 2010
  7. ncbi request reprint Regulation of bone biology by prostaglandin endoperoxide H synthases (PGHS): a rose by any other name
    Li Li
    School of Biomedical Sciences, The University of Queensland, Brisbane 4072, Australia
    Cytokine Growth Factor Rev 17:203-16. 2006
  8. doi request reprint Fracture healing via periosteal callus formation requires macrophages for both initiation and progression of early endochondral ossification
    Liza J Raggatt
    Bone and Immunology Laboratory, Mater Research Institute UQ, Translational Research Institute, The University of Queensland, Woolloongabba, Queensland, Australia UQ Centre for Clinical Research, Faculty of Health Sciences, The University of Queensland, Herston, Queensland, Australia
    Am J Pathol 184:3192-204. 2014
  9. doi request reprint Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB
    Vera M Ripoll
    Institute for Molecular Biosciences, Co operative Research Centre for Chronic Inflammatory Diseases, The University of Queensland, St Lucia, QLD 4072, Australia
    Gene 413:32-41. 2008
  10. pmc Intrauterine Bone Marrow Transplantation in Osteogenesis Imperfecta Mice Yields Donor Osteoclasts and Osteomacs but Not Osteoblasts
    Susan M Millard
    UQ Centre for Clinical Research, The University of Queensland, Herston, QLD 4029, Australia Mater Research Institute, The University of Queensland, Translational Research Institute, Woolloongabba, QLD 4102, Australia Electronic address
    Stem Cell Reports 5:682-9. 2015

Collaborators

Detail Information

Publications13

  1. doi request reprint Osteal macrophages: a new twist on coupling during bone dynamics
    Allison R Pettit
    The University of Queensland, Institute for Molecular Bioscience, Cooperative Research Centre for Chronic Inflammatory Diseases, Brisbane, QLD 4072, Australia
    Bone 43:976-82. 2008
    ..This review discusses the wider impact of macrophages in bone homeostasis and disease and proposes novel roles for OsteoMacs in bone modelling and remodelling...
  2. doi request reprint Osteal macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model
    Kylie A Alexander
    The University of Queensland, UQ Centre for Clinical Research, Herston, Australia
    J Bone Miner Res 26:1517-32. 2011
    ..This study establishes osteomacs as participants in intramembranous bone healing and as targets for primary anabolic bone therapies...
  3. doi request reprint Absence of B cells does not compromise intramembranous bone formation during healing in a tibial injury model
    Liza J Raggatt
    University of Queensland Centre for Clinical Research, The University of Queensland, Herston, Brisbane, Australia
    Am J Pathol 182:1501-8. 2013
    ..These observations support that in vivo, these lymphoid cells have minimal influence, or at most, make redundant contributions to osteoblast function during anabolic bone modeling via intramembranous mechanisms...
  4. ncbi request reprint Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and in vivo
    Ming K Chang
    Institute for Molecular Bioscience, Cooperative Research Centre for Chronic Inflammatory Diseases, University of Queensland, Brisbane, Queensland, Australia
    J Immunol 181:1232-44. 2008
    ..These observations implicate OsteoMacs, in addition to osteoclasts and osteoblasts, as principal participants in bone dynamics...
  5. doi request reprint Soluble lymphotoxin is an important effector molecule in GVHD and GVL
    Kate A Markey
    Queensland Institute of Medical Research, Brisbane, Australia
    Blood 115:122-32. 2010
    ..These data suggest that antagonists neutralizing both TNF and LTalpha3 may be effective for treatment of GVHD, particularly if residual leukemia lacks the p55 TNFR...
  6. doi request reprint An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation
    Kelli P A MacDonald
    Queensland Institute of Medical Research, Brisbane, Australia
    Blood 116:3955-63. 2010
    ..The data indicate that CSF1R signaling is required only for the maturation and replacement of resident-type monocytes and tissue macrophages, and is not required for monocyte production or inflammatory function...
  7. ncbi request reprint Regulation of bone biology by prostaglandin endoperoxide H synthases (PGHS): a rose by any other name
    Li Li
    School of Biomedical Sciences, The University of Queensland, Brisbane 4072, Australia
    Cytokine Growth Factor Rev 17:203-16. 2006
    ..The goal of this review is to summarize the current state of our knowledge of PGHS regulation of bone metabolism and to identify some of the key unresolved challenges and questions that require further study...
  8. doi request reprint Fracture healing via periosteal callus formation requires macrophages for both initiation and progression of early endochondral ossification
    Liza J Raggatt
    Bone and Immunology Laboratory, Mater Research Institute UQ, Translational Research Institute, The University of Queensland, Woolloongabba, Queensland, Australia UQ Centre for Clinical Research, Faculty of Health Sciences, The University of Queensland, Herston, Queensland, Australia
    Am J Pathol 184:3192-204. 2014
    ..Thus, macrophages represent a viable target for the development of pro-anabolic fracture treatments with a potentially broad therapeutic window...
  9. doi request reprint Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB
    Vera M Ripoll
    Institute for Molecular Biosciences, Co operative Research Centre for Chronic Inflammatory Diseases, The University of Queensland, St Lucia, QLD 4072, Australia
    Gene 413:32-41. 2008
    ..The inclusion of gpnmb in the MITF regulon suggests a role for GPNMB in mature osteoclast function...
  10. pmc Intrauterine Bone Marrow Transplantation in Osteogenesis Imperfecta Mice Yields Donor Osteoclasts and Osteomacs but Not Osteoblasts
    Susan M Millard
    UQ Centre for Clinical Research, The University of Queensland, Herston, QLD 4029, Australia Mater Research Institute, The University of Queensland, Translational Research Institute, Woolloongabba, QLD 4102, Australia Electronic address
    Stem Cell Reports 5:682-9. 2015
    ..Bone-associated donor cells were not bone-forming osteoblasts, but osteoclasts (bone resorbing cells of the hematopoietic lineage) and osteal macrophages (bone regulatory cells of the hematopoietic lineage). ..
  11. pmc Smg1 haploinsufficiency predisposes to tumor formation and inflammation
    Tara L Roberts
    Queensland Institute of Medical Research, Brisbane, QLD 4029, Australia
    Proc Natl Acad Sci U S A 110:E285-94. 2013
    ..These data suggest that the inflammation observed in Smg1 haploinsufficiency contributes to susceptibility to cancer and that Smg1-deficient animals represent a model of inflammation-enhanced cancer development...
  12. doi request reprint Conventional dendritic cells are the critical donor APC presenting alloantigen after experimental bone marrow transplantation
    Kate A Markey
    Bone Marrow Transplantation Laboratory, Queensland Institute of Medical Research, Brisbane, Australia
    Blood 113:5644-9. 2009
    ..These data have major implications for the design of therapeutic strategies post-BMT, and suggest that cDC depletion and the promotion of B-cell reconstitution may be beneficial tools for the control of alloreactivity...
  13. ncbi request reprint Vegfb gene knockout mice display reduced pathology and synovial angiogenesis in both antigen-induced and collagen-induced models of arthritis
    Arne W Mould
    QCF Transgenic Laboratory, The Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    Arthritis Rheum 48:2660-9. 2003
    ..To determine the role of vascular endothelial growth factor B (VEGF-B) in 2 mouse models of arthritis, antigen-induced arthritis (AIA) and collagen-induced arthritis (CIA)...