Graeme J O'Keefe

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. pmc Pharmacodynamic analysis of tumour perfusion assessed by 15O-water-PET imaging during treatment with sunitinib malate in patients with advanced malignancies
    Andrew M Scott
    Centre for PET, Ludwig Institute for Cancer Research and Ludwig Oncology Unit, Austin Hospital, Studley Road, Heidelberg, Victoria, 3084, Australia
    EJNMMI Res 2:31. 2012
  2. doi request reprint Radiation dosimetry of beta-amyloid tracers 11C-PiB and 18F-BAY94-9172
    Graeme J O'Keefe
    Centre for Positron Emission Tomography, Austin Hospital, Heidelberg, Victoria, Australia
    J Nucl Med 50:309-15. 2009
  3. doi request reprint Independent contribution of temporal beta-amyloid deposition to memory decline in the pre-dementia phase of Alzheimer's disease
    Gael Chetelat
    Department of Nuclear Medicine and Centre for PET, Austin Health, 145 Studley Road, Heidelberg, VIC 3084, Australia
    Brain 134:798-807. 2011
  4. ncbi request reprint Correlation of hypoxic cell fraction and angiogenesis with glucose metabolic rate in gliomas using 18F-fluoromisonidazole, 18F-FDG PET, and immunohistochemical studies
    Lawrence M Cher
    Centre for PET, Austin Hospital, Heidelberg, Victoria, Australia
    J Nucl Med 47:410-8. 2006
  5. doi request reprint L-Tyrosine Confers Residualizing Properties to a d-Amino Acid-Rich Residualizing Peptide for Radioiodination of Internalizing Antibodies
    Fook T Lee
    Tumour Targeting Program, Ludwig Institute for Cancer Research and Olivia Newton John Cancer Research Institute, Heidelberg, Victoria, Australia
    Mol Imaging 15:. 2016
  6. doi request reprint Relationship between atrophy and beta-amyloid deposition in Alzheimer disease
    Gael Chetelat
    Department of Nuclear Medicine and Center for PET, Austin Health, 145 Studley Road, Heidelberg, Victoria 3084, Australia
    Ann Neurol 67:317-24. 2010
  7. doi request reprint Toward hypoxia-selective rhenium and technetium tricarbonyl complexes
    Andrea J North
    Ludwig Institute for Cancer Research, Melbourne Austin Branch, 145 Studley Road, Heidelberg, Victoria 3084, Australia
    Inorg Chem 54:9594-610. 2015
  8. ncbi request reprint Radiation dose to PET technologists and strategies to lower occupational exposure
    Fiona O Roberts
    Department of Nuclear Medicine and Centre for PET, Austin Hospital, Melbourne, Australia
    J Nucl Med Technol 33:44-7. 2005
  9. ncbi request reprint Lack of correlation of hypoxic cell fraction and angiogenesis with glucose metabolic rate in non-small cell lung cancer assessed by 18F-Fluoromisonidazole and 18F-FDG PET
    Martin H Cherk
    Centre for PET, Austin Hospital, Heidelberg, Victoria, Australia
    J Nucl Med 47:1921-6. 2006
  10. doi request reprint Immuno-PET quantitation of de2-7 epidermal growth factor receptor expression in glioma using 124I-IMP-R4-labeled antibody ch806
    Fook T Lee
    Ludwig Institute for Cancer Research, Heidelberg, Victoria, Australia
    J Nucl Med 51:967-72. 2010

Collaborators

Detail Information

Publications11

  1. pmc Pharmacodynamic analysis of tumour perfusion assessed by 15O-water-PET imaging during treatment with sunitinib malate in patients with advanced malignancies
    Andrew M Scott
    Centre for PET, Ludwig Institute for Cancer Research and Ludwig Oncology Unit, Austin Hospital, Studley Road, Heidelberg, Victoria, 3084, Australia
    EJNMMI Res 2:31. 2012
    ..We evaluated pharmacodynamic changes in tumour perfusion using positron emission tomography (PET) imaging with 15O-water to assess biological response to sunitinib, a multitargeted tyrosine kinase inhibitor...
  2. doi request reprint Radiation dosimetry of beta-amyloid tracers 11C-PiB and 18F-BAY94-9172
    Graeme J O'Keefe
    Centre for Positron Emission Tomography, Austin Hospital, Heidelberg, Victoria, Australia
    J Nucl Med 50:309-15. 2009
    ..The radiation dosimetry of Abeta radioligands may influence their application; therefore, we calculated and compared the effective doses (EDs) of 11C-PiB and a new 18F-labeled ligand, 18F-BAY94-9172...
  3. doi request reprint Independent contribution of temporal beta-amyloid deposition to memory decline in the pre-dementia phase of Alzheimer's disease
    Gael Chetelat
    Department of Nuclear Medicine and Centre for PET, Austin Health, 145 Studley Road, Heidelberg, VIC 3084, Australia
    Brain 134:798-807. 2011
    ....
  4. ncbi request reprint Correlation of hypoxic cell fraction and angiogenesis with glucose metabolic rate in gliomas using 18F-fluoromisonidazole, 18F-FDG PET, and immunohistochemical studies
    Lawrence M Cher
    Centre for PET, Austin Hospital, Heidelberg, Victoria, Australia
    J Nucl Med 47:410-8. 2006
    ....
  5. doi request reprint L-Tyrosine Confers Residualizing Properties to a d-Amino Acid-Rich Residualizing Peptide for Radioiodination of Internalizing Antibodies
    Fook T Lee
    Tumour Targeting Program, Ludwig Institute for Cancer Research and Olivia Newton John Cancer Research Institute, Heidelberg, Victoria, Australia
    Mol Imaging 15:. 2016
    ..The aims of the study were to develop and evaluate a novel residualizing peptide for labeling internalizing antibodies with (124)I to support clinical development using immuno-positron emission tomography (PET)...
  6. doi request reprint Relationship between atrophy and beta-amyloid deposition in Alzheimer disease
    Gael Chetelat
    Department of Nuclear Medicine and Center for PET, Austin Health, 145 Studley Road, Heidelberg, Victoria 3084, Australia
    Ann Neurol 67:317-24. 2010
    ..The present study aims to assess this relationship...
  7. doi request reprint Toward hypoxia-selective rhenium and technetium tricarbonyl complexes
    Andrea J North
    Ludwig Institute for Cancer Research, Melbourne Austin Branch, 145 Studley Road, Heidelberg, Victoria 3084, Australia
    Inorg Chem 54:9594-610. 2015
    ..A (99m)Tc tricarbonyl complex with a dipyridylamine ligand bearing a nitroimidazole functional group is stable in human serum and was shown to localize in a human renal cell carcinoma (RCC; SK-RC-52) tumor in a mouse. ..
  8. ncbi request reprint Radiation dose to PET technologists and strategies to lower occupational exposure
    Fiona O Roberts
    Department of Nuclear Medicine and Centre for PET, Austin Hospital, Melbourne, Australia
    J Nucl Med Technol 33:44-7. 2005
    ..The use of PET in Australia has grown rapidly. We conducted a prospective study of the radiation exposure of technologists working in PET and evaluated the occupational radiation dose after implementation of strategies to lower exposure...
  9. ncbi request reprint Lack of correlation of hypoxic cell fraction and angiogenesis with glucose metabolic rate in non-small cell lung cancer assessed by 18F-Fluoromisonidazole and 18F-FDG PET
    Martin H Cherk
    Centre for PET, Austin Hospital, Heidelberg, Victoria, Australia
    J Nucl Med 47:1921-6. 2006
    ....
  10. doi request reprint Immuno-PET quantitation of de2-7 epidermal growth factor receptor expression in glioma using 124I-IMP-R4-labeled antibody ch806
    Fook T Lee
    Ludwig Institute for Cancer Research, Heidelberg, Victoria, Australia
    J Nucl Med 51:967-72. 2010
    ..The aim of this study was to develop a PET-based method for detecting the constitutively active mutant de2-7 EGFR, which is associated with disease progression and resistance to chemotherapy and radiotherapy in glioma...
  11. doi request reprint High striatal amyloid beta-peptide deposition across different autosomal Alzheimer disease mutation types
    Victor L Villemagne
    Department of Nuclear Medicine, Centre for Positron Emission Tomography, Austin Health, Heidelberg, Australia
    Arch Neurol 66:1537-44. 2009
    ..Mutations in the amyloid precursor protein (APP), presenilin 1 (PSEN1), and presenilin 2 (PSEN2) genes lead to increased Abeta levels before symptoms arise...