Izuru Matsumoto

Summary

Affiliation: University of Sydney
Country: Australia

Publications

  1. doi request reprint Proteomics approach in the study of the pathophysiology of alcohol-related brain damage
    Izuru Matsumoto
    Discipline of Pathology, University of Sydney, NSW, Australia
    Alcohol Alcohol 44:171-6. 2009
  2. ncbi request reprint CNS proteomes in alcohol and drug abuse and dependence
    Izuru Matsumoto
    University of Sydney, Discipline of Pathology, NSW, Australia
    Expert Rev Proteomics 4:539-52. 2007
  3. ncbi request reprint 5-HT2A and muscarinic receptors in schizophrenia: a postmortem study
    Izuru Matsumoto
    Department of Pathology, University of Sydney, NSW 2006, Australia
    Neurosci Lett 379:164-8. 2005
  4. doi request reprint Antipsychotic induced alteration of growth and proteome of rat neural stem cells
    Eakhlas Uddin Ahmed
    Psychopharmacology Laboratory, School of Psychology, University of Sydney, Sydney, NSW 2006, Australia
    Neurochem Res 37:1649-59. 2012
  5. doi request reprint Comparative proteomics in the corpus callosal sub-regions of postmortem human brain
    Mohammed A Kashem
    University of Sydney, NSW, Australia
    Neurochem Int 55:483-90. 2009
  6. ncbi request reprint Protein expression profile in the striatum of rats with methamphetamine-induced behavioral sensitization
    Takeshi Iwazaki
    Discipline of Pathology, University of Sydney, NSW, Australia
    Proteomics 7:1131-9. 2007
  7. doi request reprint Protein expression profile in the amygdala of rats with methamphetamine-induced behavioral sensitization
    Takeshi Iwazaki
    Discipline of Pathology, Department of Psychology, The University of Sydney, NSW 2006, Australia
    Neurosci Lett 435:113-9. 2008
  8. doi request reprint Effects of typical (haloperidol) and atypical (risperidone) antipsychotic agents on protein expression in rat neural stem cells
    Mohammed A Kashem
    University of Sydney, NSW, Australia
    Neurochem Int 55:558-65. 2009
  9. doi request reprint Differential protein expression in the corpus callosum (body) of human alcoholic brain
    Mohammed Abul Kashem
    University of Sydney, New South Wales, Australia
    J Neurochem 110:486-95. 2009
  10. ncbi request reprint Cerebellar vermis proteome of chronic alcoholic individuals
    Kimberley Alexander-Kaufman
    Discipline of Pathology, Faculty of Medicine, The University of Sydney, New South Wales, Australia
    Alcohol Clin Exp Res 31:1286-96. 2007

Collaborators

Detail Information

Publications36

  1. doi request reprint Proteomics approach in the study of the pathophysiology of alcohol-related brain damage
    Izuru Matsumoto
    Discipline of Pathology, University of Sydney, NSW, Australia
    Alcohol Alcohol 44:171-6. 2009
    ....
  2. ncbi request reprint CNS proteomes in alcohol and drug abuse and dependence
    Izuru Matsumoto
    University of Sydney, Discipline of Pathology, NSW, Australia
    Expert Rev Proteomics 4:539-52. 2007
    ..Focusing on CNS proteomics, we aim to review and update current knowledge in this rapidly advancing area...
  3. ncbi request reprint 5-HT2A and muscarinic receptors in schizophrenia: a postmortem study
    Izuru Matsumoto
    Department of Pathology, University of Sydney, NSW 2006, Australia
    Neurosci Lett 379:164-8. 2005
    ..No significant changes in the density of M1/M4 receptors was observed in these three regions between the two groups. These findings support a possible involvement of the serotonergic system in the pathology of schizophrenia...
  4. doi request reprint Antipsychotic induced alteration of growth and proteome of rat neural stem cells
    Eakhlas Uddin Ahmed
    Psychopharmacology Laboratory, School of Psychology, University of Sydney, Sydney, NSW 2006, Australia
    Neurochem Res 37:1649-59. 2012
    ..These results may explain RS induced repairing of neural damage caused by a wide variety of neural diseases including schizophrenia...
  5. doi request reprint Comparative proteomics in the corpus callosal sub-regions of postmortem human brain
    Mohammed A Kashem
    University of Sydney, NSW, Australia
    Neurochem Int 55:483-90. 2009
    ..Protein expression maps of these regions can be used as a reference source for future studies to investigate the molecular basis of functional differences and degree of pathogenesis of various neurodegenerative diseases of the CC...
  6. ncbi request reprint Protein expression profile in the striatum of rats with methamphetamine-induced behavioral sensitization
    Takeshi Iwazaki
    Discipline of Pathology, University of Sydney, NSW, Australia
    Proteomics 7:1131-9. 2007
    ..These proteins can be related to underlying mechanisms of MAP-induced behavioral sensitization, indicating cytoskeletal modification, and altered synaptic function...
  7. doi request reprint Protein expression profile in the amygdala of rats with methamphetamine-induced behavioral sensitization
    Takeshi Iwazaki
    Discipline of Pathology, Department of Psychology, The University of Sydney, NSW 2006, Australia
    Neurosci Lett 435:113-9. 2008
    ..Changes of these protein expressions in the AMG could be associated with the mechanism underlying behavioral sensitization...
  8. doi request reprint Effects of typical (haloperidol) and atypical (risperidone) antipsychotic agents on protein expression in rat neural stem cells
    Mohammed A Kashem
    University of Sydney, NSW, Australia
    Neurochem Int 55:558-65. 2009
    ..Identified proteins in this experiment may be useful in future studies of NSCs differentiation and/or understanding in molecular mechanisms of different neural diseases including schizophenia...
  9. doi request reprint Differential protein expression in the corpus callosum (body) of human alcoholic brain
    Mohammed Abul Kashem
    University of Sydney, New South Wales, Australia
    J Neurochem 110:486-95. 2009
    ..Therefore, alcohol-induced microstructural damage detected by image analysis in the CC, possibly involves multiple biochemical mechanisms...
  10. ncbi request reprint Cerebellar vermis proteome of chronic alcoholic individuals
    Kimberley Alexander-Kaufman
    Discipline of Pathology, Faculty of Medicine, The University of Sydney, New South Wales, Australia
    Alcohol Clin Exp Res 31:1286-96. 2007
    ....
  11. doi request reprint A long hangover from party drugs: residual proteomic changes in the hippocampus of rats 8 weeks after γ-hydroxybutyrate (GHB), 3,4-methylenedioxymethamphetamine (MDMA) or their combination
    Petra S van Nieuwenhuijzen
    School of Psychology, University of Sydney, Camperdown, Sydney, NSW 2006, Australia
    Neurochem Int 56:871-7. 2010
    ..These results provide some insight into the molecular pathways possibly underlying the lasting cognitive deficits arising from GHB and/or MDMA use...
  12. doi request reprint Anterior hippocampus in schizophrenia pathogenesis: molecular evidence from a proteome study
    Maryam Nesvaderani
    Discipline of Pathology, University of Sydney, New South Wales, Australia
    Aust N Z J Psychiatry 43:310-22. 2009
    ..The purpose of the present study was to identify differentially expressed proteins in the anterior and posterior hippocampus of brains of schizophrenia patients compared to neurologically healthy controls...
  13. doi request reprint Differential protein expression in the corpus callosum (genu) of human alcoholics
    Mohammed Abul Kashem
    Discipline of Pathology, University of Sydney, Sydney, NSW 2006, Australia
    Neurochem Int 53:1-11. 2008
    ..It is therefore suggested that both hepatic and nutritious factors might be underlying the mechanisms of microstructural damage detected by DTI...
  14. ncbi request reprint Adolescent rats find repeated Delta(9)-THC less aversive than adult rats but display greater residual cognitive deficits and changes in hippocampal protein expression following exposure
    Heidi R Quinn
    School of Psychology, University of Sydney, Sydney, NSW, Australia
    Neuropsychopharmacology 33:1113-26. 2008
    ....
  15. ncbi request reprint Differential protein expression in the corpus callosum (splenium) of human alcoholics: a proteomics study
    Mohammed Abul Kashem
    Discipline of Pathology, University of Sydney, Blackburn Building D06, NSW 2006, Australia
    Neurochem Int 50:450-9. 2007
    ..Our data also indicate the importance of other pathways including oxidative stress, lipid peroxidation and apoptosis as potential causes of alcohol-induced brain damage...
  16. doi request reprint Alcoholism: protein expression profiles in a human hippocampal model
    Haruka Matsumoto
    The University of Sydney, Discipline of Pathology, NSW 2006, Australia
    Expert Rev Proteomics 5:321-31. 2008
    ..g., Alzheimer's disease, alcoholism and schizophrenia) are still sparse, and further investigation is warranted to understand the underlying mechanisms...
  17. doi request reprint Intermittent hypercapnic hypoxia induced protein changes in the piglet hippocampus identified by MALDI-TOF-MS
    Samantha Tang
    Discipline of Pediatrics and Child Health, University of Sydney, Sydney, NSW 2006, Australia
    Neurochem Res 34:2215-25. 2009
    ....
  18. doi request reprint Proteomic analysis of protein expression in the eutopic endometrium of women with endometriosis
    Sara Ten Have
    Department of Obstetrics and Gynaecology, Queen Elizabeth II Research Institute for Mothers and Infants, University of Sydney, Sydney, NSW, Australia
    Proteomics Clin Appl 1:1243-51. 2007
    ..The differences seen in this pilot study show the potential of proteomic applications in endometriosis research for determining diagnostics and pathogenesis characterisation, as well as the future development of targeted drug treatments...
  19. doi request reprint Viruses and the immune system: their roles in seizure cascade development
    Daniel R Getts
    The Discipline of Pathology, School of Medical Sciences, The University of Sydney, Sydney, New South Wales, Australia
    J Neurochem 104:1167-76. 2008
    ....
  20. ncbi request reprint How important are brain banks for alcohol research?
    Clive Harper
    University of Sydney and Royal Prince Alfred Hospital, New South Wales, Australia
    Alcohol Clin Exp Res 27:310-23. 2003
    ..at the 2002 RSA/ISBRA Meeting in San Francisco, organized and chaired by Clive Harper and co-chaired by Izuru Matsumoto. The presentations were (1) Introduction, by Clive Harper; (2) The quality of tissue-a critical issue, by ..
  21. doi request reprint A proteome analysis of the dorsolateral prefrontal cortex in human alcoholic patients
    Kimberley Alexander-Kaufman
    Discipline of Pathology, Faculty of Medicine, The University of Sydney, NSW, Sydney, Australia
    Proteomics Clin Appl 1:62-72. 2007
    ....
  22. doi request reprint Abnormal pathways in the genu of the corpus callosum in schizophrenia pathogenesis: a proteome study
    Sinthuja Sivagnanasundaram
    Schizophrenia Research Institute, Sydney, Australia Discipline of Pathology, University of Sydney, Sydney, Australia
    Proteomics Clin Appl 1:1291-305. 2007
    ..This initial pool of protein candidates and abnormal functional pathways opens up avenues for further investigation of molecular mechanisms involving the CC in schizophrenia pathogenesis and symptoms...
  23. ncbi request reprint Ethanol and brain damage
    Clive Harper
    Department of Pathology, University of Sydney, New South Wales, Australia 2006
    Curr Opin Pharmacol 5:73-8. 2005
    ..The development of high-throughput, non-hypothesis-driven approaches using DNA microarrays and proteomics might also provide clues to this important problem...
  24. ncbi request reprint Protein expression profile in the striatum of acute methamphetamine-treated rats
    Takeshi Iwazaki
    Discipline of Pathology, The University of Sydney, NSW 2006, Australia
    Brain Res 1097:19-25. 2006
    ..In the present study, we aim to identify protein expression profiles in the striatum (ST) of acute low dose MAP (1 mg/kg)-treated rats using 2-DE proteomics...
  25. ncbi request reprint Effects of chronic risperidone treatment on the striatal protein profiles in rats
    Elizabeth O'Brien
    Discipline of Pathology, Blackburn Building, D06, The University of Sydney, NSW, 2006, Australia
    Brain Res 1113:24-32. 2006
    ..These results suggest that possible mechanisms involved in APD-induced EPS include metabolic dysfunction and oxidative stress...
  26. doi request reprint Altered proteins of the anterior cingulate cortex white matter proteome in schizophrenia
    Danielle Clark
    Department of Pathology, The University of Sydney, Sydney, Australia
    Proteomics Clin Appl 1:157-66. 2007
    ..These proteomic data suggest that the brain circuitry involving the ACC white matter tracts is altered in schizophrenia, possibly caused by depleted glucose metabolism and altered structural components of this region...
  27. ncbi request reprint Behavioural effects of chronic haloperidol and risperidone treatment in rats
    Tim Karl
    Neuroscience Institute of Schizophrenia and Allied Disorders NISAD, Darlinghurst, Sydney, NSW, Australia
    Behav Brain Res 171:286-94. 2006
    ..Differences in the behavioural profile of haloperidol and risperidone, which were revealed by a comprehensive phenotyping strategy, are likely due to the unique receptor activation profiles of these APDs...
  28. ncbi request reprint Selective reduction of chromogranin A-like immunoreactivities in the prefrontal cortex of schizophrenic subjects: a postmortem study
    Takeshi Iwazaki
    Department of Neuropsychiatry, School of Medicine, Fukushima Medical University, Hikarigaoka 1 960 1295, Japan
    Neurosci Lett 367:293-7. 2004
    ....
  29. ncbi request reprint [Current status and problems associated with studies of the postmortem brain obtained from schizophrenic patients]
    Shinichi Niwa
    Seishin Shinkeigaku Zasshi 106:958-68. 2004
  30. ncbi request reprint Expression of human neuronal protein 22, a novel cytoskeleton-associated protein, was decreased in the anterior cingulate cortex of schizophrenia
    Masayuki Ito
    Department of Pathology, School of Medicine, Fukushima Medical University, Fukushima, Hikarigaoka 1 960 1295, Japan
    Neurosci Lett 378:125-30. 2005
    ..These results suggest that altered expression of hNP22 may be associated with modifications in neuronal cytoarchitecture leading to dysregulation of neural signal transduction in the anterior cingulate cortex of the schizophrenia brain...
  31. ncbi request reprint Genome-wide expression analysis detects eight genes with robust alterations specific to bipolar I disorder: relevance to neuronal network perturbation
    Noriaki Nakatani
    Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Saitama, Japan
    Hum Mol Genet 15:1949-62. 2006
    ..Finally, gene network analysis using the currently obtained expression data highlighted cellular growth and nervous system development pathways as potential targets in the molecular pathophysiology of bipolar disorder...
  32. ncbi request reprint Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics
    Traute Flatscher-Bader
    Department of Biochemistry and Molecular Biology, School of Molecular and Microbial Sciences, The University of Queensland, Queensland, Australia
    J Neurochem 93:359-70. 2005
    ....
  33. ncbi request reprint Expression of hNP22 is altered in the frontal cortex and hippocampus of the alcoholic human brain
    Iris Depaz
    Department of Biochemistry and Molecular Biology, School of Molecular and Microbial Sciences, University of Queensland, St Lucia, Brisbane, Australia
    Alcohol Clin Exp Res 27:1481-8. 2003
    ..hNP22 has high homology with a rat protein (rNP22). These proteins also share homology with a number of cytoskeleton-interacting proteins...
  34. pmc Protein expression in the nucleus accumbens of rats exposed to developmental vitamin D deficiency
    John McGrath
    Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Richlands, Australia
    PLoS ONE 3:e2383. 2008
    ..Because the nucleus accumbens has been implicated in neuropsychiatric disorders, in the current study we examined protein expression in this region in adult rats exposed to DVD deficiency..
  35. ncbi request reprint Failure to support a genetic contribution of AKT1 polymorphisms and altered AKT signaling in schizophrenia
    Masayuki Ide
    Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Saitama, Japan
    J Neurochem 99:277-87. 2006
    ..Collectively, this study failed to support reduced signaling of the AKT-GSK3beta molecular cascade in schizophrenia...
  36. ncbi request reprint Role of IFN-gamma in an experimental murine model of West Nile virus-induced seizures
    Daniel R Getts
    The Discipline of Pathology, The University of Sydney, Sydney, New South Wales, Australia
    J Neurochem 103:1019-30. 2007
    ..Our data show that IFN-gamma plays an important role in the development of the excitatory seizure pathways in the brain and that these cascades become pathogenic in encephalitic WNV infection...