I M MacLeod

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. pmc Exploiting biological priors and sequence variants enhances QTL discovery and genomic prediction of complex traits
    I M MacLeod
    Faculty of Veterinary and Agricultural Science, University of Melbourne, Victoria, 3010, Australia
    BMC Genomics 17:144. 2016
  2. pmc The effects of demography and long-term selection on the accuracy of genomic prediction with sequence data
    Iona M Macleod
    Faculty of Veterinary and Agricultural Science, University of Melbourne, Melbourne, Victoria 3010, Australia Dairy Futures Cooperative Research Centre, La Trobe University, Bundoora, Victoria 3083, Australia
    Genetics 198:1671-84. 2014
  3. pmc Inferring demography from runs of homozygosity in whole-genome sequence, with correction for sequence errors
    Iona M Macleod
    Department of Agriculture and Food Systems, Melbourne School of Land and Environment, University of Melbourne, Victoria, Australia
    Mol Biol Evol 30:2209-23. 2013
  4. doi request reprint A novel predictor of multilocus haplotype homozygosity: comparison with existing predictors
    I M MacLeod
    Melbourne School of Land and Environment, University of Melbourne, VIC 3010, Australia
    Genet Res (Camb) 91:413-26. 2009
  5. doi request reprint Power of a genome scan to detect and locate quantitative trait loci in cattle using dense single nucleotide polymorphisms
    I M MacLeod
    Cooperative Research Centre for Beef Genetic Technologies, Armidale, NSW, Australia
    J Anim Breed Genet 127:133-42. 2010
  6. pmc Genetics of complex traits: prediction of phenotype, identification of causal polymorphisms and genetic architecture
    M E Goddard
    Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Melbourne, Victoria 3010, Australia Department of Economic Development, Jobs, Transport and Resources, AgriBio, La Trobe University, Bundoora, Victoria 3083, Australia
    Proc Biol Sci 283:. 2016

Detail Information

Publications6

  1. pmc Exploiting biological priors and sequence variants enhances QTL discovery and genomic prediction of complex traits
    I M MacLeod
    Faculty of Veterinary and Agricultural Science, University of Melbourne, Victoria, 3010, Australia
    BMC Genomics 17:144. 2016
    ..While this assumption is reasonable for SNP array genotypes, it is less sensible if genotypes are whole-genome sequence variants which should include causal variants...
  2. pmc The effects of demography and long-term selection on the accuracy of genomic prediction with sequence data
    Iona M Macleod
    Faculty of Veterinary and Agricultural Science, University of Melbourne, Melbourne, Victoria 3010, Australia Dairy Futures Cooperative Research Centre, La Trobe University, Bundoora, Victoria 3083, Australia
    Genetics 198:1671-84. 2014
    ..This study demonstrates the joint influence of demography and selection on accuracy of prediction and improves our understanding of how best to exploit sequence for genomic prediction...
  3. pmc Inferring demography from runs of homozygosity in whole-genome sequence, with correction for sequence errors
    Iona M Macleod
    Department of Agriculture and Food Systems, Melbourne School of Land and Environment, University of Melbourne, Victoria, Australia
    Mol Biol Evol 30:2209-23. 2013
    ..Our approach can be applied to whole-genome sequence from any diploid species and can be scaled up to use sequence from multiple individuals. ..
  4. doi request reprint A novel predictor of multilocus haplotype homozygosity: comparison with existing predictors
    I M MacLeod
    Melbourne School of Land and Environment, University of Melbourne, VIC 3010, Australia
    Genet Res (Camb) 91:413-26. 2009
    ..Our method is practical for use with very large numbers of individuals and dense genome wide polymorphic DNA data. It has potential applications in inferring ancestral population history and QTL mapping studies...
  5. doi request reprint Power of a genome scan to detect and locate quantitative trait loci in cattle using dense single nucleotide polymorphisms
    I M MacLeod
    Cooperative Research Centre for Beef Genetic Technologies, Armidale, NSW, Australia
    J Anim Breed Genet 127:133-42. 2010
    ..Selective genotyping also resulted in a significant increase in false positives, even when pedigree structure was accounted for...
  6. pmc Genetics of complex traits: prediction of phenotype, identification of causal polymorphisms and genetic architecture
    M E Goddard
    Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Melbourne, Victoria 3010, Australia Department of Economic Development, Jobs, Transport and Resources, AgriBio, La Trobe University, Bundoora, Victoria 3083, Australia
    Proc Biol Sci 283:. 2016
    ..Methods of predicting future phenotypes, collectively known as genomic selection or genomic prediction, have been widely adopted in livestock and crop breeding, leading to increased rates of genetic improvement. ..