Z Khalil

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. ncbi Sympathetic modulation of sensory nerve activity with age: human and rodent skin models
    Z Khalil
    National Ageing Research Institute, North West Hospital, Parkville, Victoria, Australia
    Clin Exp Pharmacol Physiol 24:883-6. 1997
  2. ncbi Free radicals contribute to the reduction in peripheral vascular responses and the maintenance of thermal hyperalgesia in rats with chronic constriction injury
    Z Khalil
    National Ageing Research Institute, University of Melbourne, Parkville, Victoria, Australia
    Pain 79:31-7. 1999
  3. ncbi Modulation of peripheral inflammation by locally administered endomorphin-1
    Z Khalil
    National Ageing Research Institute, University of Melbourne, Parkville, Victoria, Australia
    Inflamm Res 48:550-6. 1999
  4. ncbi Differential involvement of conotoxin-sensitive mechanisms in neurogenic vasodilatation responses: effects of age
    Z Khalil
    National Ageing Research Institute, University of Melbourne, Poplar Road, Parkville, Victoria, Australia 3052
    J Gerontol A Biol Sci Med Sci 56:B356-63. 2001
  5. ncbi A role for free radicals and nitric oxide in delayed recovery in aged rats with chronic constriction nerve injury
    Z Khalil
    National Ageing Research Institute, University of Melbourne, Melbourne, Victoria, Australia
    Free Radic Biol Med 31:430-9. 2001
  6. ncbi Mitochondrial DNA deletions parallel age-linked decline in rat sensory nerve function
    P Nagley
    Department of Biochemistry and Molecular Biology, Monash University, 3800, Clayton, Victoria, Australia
    Neurobiol Aging 22:635-43. 2001
  7. pmc Nitric oxide and sensory nerves are involved in the vasodilator response to acetylcholine but not calcitonin gene-related peptide in rat skin microvasculature
    V Ralevic
    National Research Institute of Gerontology and Geriatric Medicine, North West Hospital Mount Royal Campus, Parkville, Australia
    Br J Pharmacol 106:650-5. 1992
  8. ncbi Modulation of inflammation by reactive oxygen species: implications for aging and tissue repair
    B Khodr
    National Aging Research Institute, University of Melbourne, Parkville, Victoria, Australia
    Free Radic Biol Med 30:1-8. 2001
  9. ncbi Effects of aging on neurogenic vasodilator responses evoked by transcutaneous electrical nerve stimulation: relevance to wound healing
    Z Khalil
    National Ageing Research Institute, University of Melbourne, Victoria, Australia
    J Gerontol A Biol Sci Med Sci 55:B257-63. 2000
  10. ncbi cis-Urocanic acid stimulates neuropeptide release from peripheral sensory nerves
    Z Khalil
    National Ageing Research Institute, University of Melbourne, Parkville, Victoria, Australia
    J Invest Dermatol 117:886-91. 2001

Detail Information

Publications14

  1. ncbi Sympathetic modulation of sensory nerve activity with age: human and rodent skin models
    Z Khalil
    National Ageing Research Institute, North West Hospital, Parkville, Victoria, Australia
    Clin Exp Pharmacol Physiol 24:883-6. 1997
    ....
  2. ncbi Free radicals contribute to the reduction in peripheral vascular responses and the maintenance of thermal hyperalgesia in rats with chronic constriction injury
    Z Khalil
    National Ageing Research Institute, University of Melbourne, Parkville, Victoria, Australia
    Pain 79:31-7. 1999
    ..We raise the possibility that common mechanisms may govern the changes in neuropathic pain and in the peripheral neurogenic vascular responses in tissues innervated by the injured nerve...
  3. ncbi Modulation of peripheral inflammation by locally administered endomorphin-1
    Z Khalil
    National Ageing Research Institute, University of Melbourne, Parkville, Victoria, Australia
    Inflamm Res 48:550-6. 1999
    ..The aim of this study was to examine the ability of endomorphin-1 (EM-1) to modulate the inflammatory response under different injury conditions...
  4. ncbi Differential involvement of conotoxin-sensitive mechanisms in neurogenic vasodilatation responses: effects of age
    Z Khalil
    National Ageing Research Institute, University of Melbourne, Poplar Road, Parkville, Victoria, Australia 3052
    J Gerontol A Biol Sci Med Sci 56:B356-63. 2001
    ..The current results have important practical implications for improving tissue repair in the aged...
  5. ncbi A role for free radicals and nitric oxide in delayed recovery in aged rats with chronic constriction nerve injury
    Z Khalil
    National Ageing Research Institute, University of Melbourne, Melbourne, Victoria, Australia
    Free Radic Biol Med 31:430-9. 2001
    ..Ironically, this study also reveals a positive role for free radicals in tissue repair and raises the notion that early intervention with antioxidants could exert a negative effect on repair of injured nerves...
  6. ncbi Mitochondrial DNA deletions parallel age-linked decline in rat sensory nerve function
    P Nagley
    Department of Biochemistry and Molecular Biology, Monash University, 3800, Clayton, Victoria, Australia
    Neurobiol Aging 22:635-43. 2001
    ..Alternatively, loss of mitochondrial DNA integrity and physiological decline may be consequences of the same factor, such as oxidative stress...
  7. pmc Nitric oxide and sensory nerves are involved in the vasodilator response to acetylcholine but not calcitonin gene-related peptide in rat skin microvasculature
    V Ralevic
    National Research Institute of Gerontology and Geriatric Medicine, North West Hospital Mount Royal Campus, Parkville, Australia
    Br J Pharmacol 106:650-5. 1992
    ..The vasodilator mediator(s) released by ACh from sensory nerves acts largely independently of NO.7. The vasodilator response to CGRP is independent of a prejunctional action on sensory nerves and of NO...
  8. ncbi Modulation of inflammation by reactive oxygen species: implications for aging and tissue repair
    B Khodr
    National Aging Research Institute, University of Melbourne, Parkville, Victoria, Australia
    Free Radic Biol Med 30:1-8. 2001
    ..We contend that the role of ROS in modulating inflammation should be considered when designing treatment protocols to accelerate tissue repair...
  9. ncbi Effects of aging on neurogenic vasodilator responses evoked by transcutaneous electrical nerve stimulation: relevance to wound healing
    Z Khalil
    National Ageing Research Institute, University of Melbourne, Victoria, Australia
    J Gerontol A Biol Sci Med Sci 55:B257-63. 2000
    ..We contend that low-frequency TENS can improve the vascular response of old rats. In addition, wound healing in aged rats can be accelerated by peripheral activation of sensory nerves at low-frequency electrical stimulation parameters...
  10. ncbi cis-Urocanic acid stimulates neuropeptide release from peripheral sensory nerves
    Z Khalil
    National Ageing Research Institute, University of Melbourne, Parkville, Victoria, Australia
    J Invest Dermatol 117:886-91. 2001
    ..cis-Urocanic-acid-induced neuropeptides may also contribute to ultraviolet-B-induced cutaneous inflammation and alterations to Langerhans cell activity...
  11. ncbi The relationship between propagated contractions and pseudoaffective changes in blood pressure in response to intestinal distension
    A Timar-Peregrin
    Department of Anatomy and Cell Biology and Centre for Neuroscience, The University of Melbourne, Victoria, Australia
    Neurogastroenterol Motil 13:575-84. 2001
    ....
  12. ncbi Impaired peripheral endothelial microvascular responsiveness in Alzheimer's disease
    Z Khalil
    Department of Biochemistry and Molecular Biology, University of Melbourne, Melbourne Victoria, Australia
    J Alzheimers Dis 11:25-32. 2007
    ..The concept that the neurotoxicity of amyloid beta protein could partly result from vascular effects that may be detected in peripheral microcirculation is new...
  13. ncbi B1 and B2 antagonists and bradykinin-induced blood flow in rat skin inflammation
    T Cao
    Centre for Cardiovascular Biology and Medicine, King s College, London, UK
    Inflamm Res 51:295-9. 2002
    ..The aim of the present study was to examine the contribution of the two kinin receptors B1 and B2 to the increased blood flow observed in response to bradykinin (BK) in a blister model under different injury conditions...
  14. ncbi Neurovascular changes after four-layer compression bandaging in people with chronic venous leg ulcers
    R Ogrin
    Austin Health, Endocrinology Centre of Excellence, Heidelberg Repatriation Hospital, Heidelberg, Australia
    Phlebology 22:49-55. 2007
    ....