Elizabeth G Holliday

Summary

Affiliation: University of Newcastle
Country: Australia

Publications

  1. pmc Common variants at 6p21.1 are associated with large artery atherosclerotic stroke
    Elizabeth G Holliday
    Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia
    Nat Genet 44:1147-51. 2012
  2. pmc Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis
    Elizabeth G Holliday
    Centre for Clinical Epidemiology and Biostatistics, and School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia
    PLoS ONE 8:e53830. 2013
  3. pmc Differences in Common Genetic Predisposition to Ischemic Stroke by Age and Sex
    Matthew Traylor
    From the Stroke Research Group, Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom M T, L C A R J, S B, H S M School of Medicine and Public Health E G H School of Nursing and Midwifery J M M, University of Newcastle, Callaghan, Newcastle, Australia Clinical Research Design, IT and Statistical Support Unit, Hunter Medical Research Institute, New Lambton Heights, Newcastle, Australia E G H, C L Institute for Stroke and Dementia Research, Klinikum der Universitat Munchen, Ludwig Maximilians Universitat, Munich, Germany R M, M D Centre for Clinical Brain Sciences and Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom C S Stroke Prevention Research Unit, Nuffield Department of Clinical Neuroscience, University of Oxford, Oxford, United Kingdom P M R Hunter Medical Research Institute, New Lambton Heights, Newcastle, Australia J M M Stroke Research Program, School of Medicine and Adelaide Center for Neuroscience Research, University of Adelaide, Adelaide, South Australia, Australia S A K Department of Cerebrovascular Disease, IRCCS Istituto Neurologico Carlo Besta, Milan, Germany
    Stroke 46:3042-7. 2015
  4. doi request reprint Concordance between direct and imputed APOE genotypes using 1000 Genomes data
    Christopher Oldmeadow
    University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia
    J Alzheimers Dis 42:391-3. 2014
  5. pmc Polygenic overlap between kidney function and large artery atherosclerotic stroke
    Elizabeth G Holliday
    From the School of Medicine and Public Health E G H, J S, M M, J A and School of Nursing and Midwifery J M, University of Newcastle, Australia Clinical Research Design, IT and Statistical Support Unit E G H, C O, J A, Hunter Medical Research Institute J M, R J S, C L, Newcastle, Australia Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK M T, S B, H S M Institute for Stroke and Dementia Research, Klinikum der Universitat Munchen, Ludwig Maximilians Universitat, Munich, Germany R M, M D Stroke Research Program, School of Medicine and Adelaide Center for Neuroscience Research, University of Adelaide, Australia S A K Neurology Department, Gosford Hospital, Australia J S School of Medicine and Pharmacology, The University of Western Australia, Perth, Australia G J H Neurology Department, Sir Charles Gairdner Hospital, Perth, Australia G J H Division of Clinical Neurosciences, University of Edinburgh, UK C S Stroke Prevention Research Unit
    Stroke 45:3508-13. 2014
  6. pmc Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer
    Tracy A O'Mara
    Department of Genetics and Computational Biology QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, Queensland 4006, Australia Wellcome Trust Centre for Human Genetics University of Oxford, Oxford OX3 7BN, UK Department of Public Health and Primary Care Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK Hunter Medical Research Institute John Hunter Hospital, Newcastle, New South Wales 2305, Australia School of Medicine and Public Health Centre for Clinical Epidemiology and Biostatistics, University of Newcastle, Newcastle, New South Wales 2305, Australia Hunter Area Pathology Service John Hunter Hospital, Newcastle, New South Wales 2305, Australia Centre for Information Based Medicine School of Biomedical Sciences and Pharmacy School of Medicine and Public Health University of Newcastle, Newcastle, New South Wales 2308, Australia Department of Oncology Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK Department of Clinical Genetics St George s, University of London, London SW17 0RE, UK Division of Hematology Oncology Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095, USA Department of Gynecology and Obstetrics University Hospital Erlangen, Friedrich Alexander University Erlangen Nuremberg, Erlangen 91054, Germany Institute of Human Genetics University Hospital Erlangen, Friedrich Alexander University Erlangen Nuremberg, Second Xiangya Hospital
    Endocr Relat Cancer 22:851-61. 2015
  7. pmc Genetic overlap between diagnostic subtypes of ischemic stroke
    Elizabeth G Holliday
    From the School of Medicine and Public Health E G H, J A, School of Biomedical Sciences and Pharmacy L F L, R J S, and School of Nursing and Midwifery J M M, University of Newcastle, Australia Clinical Research Design, IT and Statistical Support Unit, Public Health Research Program, Hunter Medical Research Institute, Newcastle, Australia E G H, C O, J A Department of Clinical Neurosciences, University of Cambridge, UK M T, S B, H S M Institute for Stroke and Dementia Research, Klinikum der Universität Mün chen, Ludwig Maximilians Universitat, Munich, Germany R M, M D Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA G F, J R Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA G F, J R Clinical Trial Service Unit and Epidemiological Studies Unit J C H, R C and Stroke Prevention Research Unit, Nuffield Department of Clinical Neuroscience P M R, University of Oxford, UK Department of Medicine Y C C, B D M and Department of Neurology J W C
    Stroke 46:615-9. 2015
  8. pmc Confirmation of childhood acute lymphoblastic leukemia variants, ARID5B and IKZF1, and interaction with parental environmental exposures
    Tiffany Jane Evans
    Centre for Bioinformatics, Biomarker Discovery and Information Based Medicine, Hunter Medical Research Institute, Newcastle, New South Wales, Australia School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia
    PLoS ONE 9:e110255. 2014
  9. pmc STaRRRT: a table of short tandem repeats in regulatory regions of the human genome
    Katherine A Bolton
    Centre for Information Based Medicine, Hunter Medical Research Institute, Newcastle, NSW, Australia
    BMC Genomics 14:795. 2013
  10. pmc Continuing difficulties in interpreting CNV data: lessons from a genome-wide CNV association study of Australian HNPCC/lynch syndrome patients
    Bente A Talseth-Palmer
    School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, NSW, Australia
    BMC Med Genomics 6:10. 2013

Detail Information

Publications14

  1. pmc Common variants at 6p21.1 are associated with large artery atherosclerotic stroke
    Elizabeth G Holliday
    Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia
    Nat Genet 44:1147-51. 2012
    ..15, P=3.9×10(-4); discovery and replication combined OR=1.21, P=4.7×10(-8)). This study identifies a genetic risk locus for LAA and shows how analyzing etiological subtypes may better identify genetic risk alleles for ischemic stroke...
  2. pmc Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis
    Elizabeth G Holliday
    Centre for Clinical Epidemiology and Biostatistics, and School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia
    PLoS ONE 8:e53830. 2013
    ....
  3. pmc Differences in Common Genetic Predisposition to Ischemic Stroke by Age and Sex
    Matthew Traylor
    From the Stroke Research Group, Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom M T, L C A R J, S B, H S M School of Medicine and Public Health E G H School of Nursing and Midwifery J M M, University of Newcastle, Callaghan, Newcastle, Australia Clinical Research Design, IT and Statistical Support Unit, Hunter Medical Research Institute, New Lambton Heights, Newcastle, Australia E G H, C L Institute for Stroke and Dementia Research, Klinikum der Universitat Munchen, Ludwig Maximilians Universitat, Munich, Germany R M, M D Centre for Clinical Brain Sciences and Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom C S Stroke Prevention Research Unit, Nuffield Department of Clinical Neuroscience, University of Oxford, Oxford, United Kingdom P M R Hunter Medical Research Institute, New Lambton Heights, Newcastle, Australia J M M Stroke Research Program, School of Medicine and Adelaide Center for Neuroscience Research, University of Adelaide, Adelaide, South Australia, Australia S A K Department of Cerebrovascular Disease, IRCCS Istituto Neurologico Carlo Besta, Milan, Germany
    Stroke 46:3042-7. 2015
    ..Whether these arise because of different genetic influences remained untested. Here, we use data from 4 genome-wide association data sets to study the relationship between genetic influence on stroke with both age and sex...
  4. doi request reprint Concordance between direct and imputed APOE genotypes using 1000 Genomes data
    Christopher Oldmeadow
    University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia
    J Alzheimers Dis 42:391-3. 2014
    ..81 and 0.84, respectively. More stringent thresholds around allele number estimates can increase this agreement to 90-97% and kappas of 0.90-0.93...
  5. pmc Polygenic overlap between kidney function and large artery atherosclerotic stroke
    Elizabeth G Holliday
    From the School of Medicine and Public Health E G H, J S, M M, J A and School of Nursing and Midwifery J M, University of Newcastle, Australia Clinical Research Design, IT and Statistical Support Unit E G H, C O, J A, Hunter Medical Research Institute J M, R J S, C L, Newcastle, Australia Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK M T, S B, H S M Institute for Stroke and Dementia Research, Klinikum der Universitat Munchen, Ludwig Maximilians Universitat, Munich, Germany R M, M D Stroke Research Program, School of Medicine and Adelaide Center for Neuroscience Research, University of Adelaide, Australia S A K Neurology Department, Gosford Hospital, Australia J S School of Medicine and Pharmacology, The University of Western Australia, Perth, Australia G J H Neurology Department, Sir Charles Gairdner Hospital, Perth, Australia G J H Division of Clinical Neurosciences, University of Edinburgh, UK C S Stroke Prevention Research Unit
    Stroke 45:3508-13. 2014
    ..We investigated whether these associations may reflect shared heritability because of a common polygenic basis and whether this differed for IS subtypes...
  6. pmc Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer
    Tracy A O'Mara
    Department of Genetics and Computational Biology QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, Queensland 4006, Australia Wellcome Trust Centre for Human Genetics University of Oxford, Oxford OX3 7BN, UK Department of Public Health and Primary Care Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK Hunter Medical Research Institute John Hunter Hospital, Newcastle, New South Wales 2305, Australia School of Medicine and Public Health Centre for Clinical Epidemiology and Biostatistics, University of Newcastle, Newcastle, New South Wales 2305, Australia Hunter Area Pathology Service John Hunter Hospital, Newcastle, New South Wales 2305, Australia Centre for Information Based Medicine School of Biomedical Sciences and Pharmacy School of Medicine and Public Health University of Newcastle, Newcastle, New South Wales 2308, Australia Department of Oncology Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK Department of Clinical Genetics St George s, University of London, London SW17 0RE, UK Division of Hematology Oncology Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095, USA Department of Gynecology and Obstetrics University Hospital Erlangen, Friedrich Alexander University Erlangen Nuremberg, Erlangen 91054, Germany Institute of Human Genetics University Hospital Erlangen, Friedrich Alexander University Erlangen Nuremberg, Second Xiangya Hospital
    Endocr Relat Cancer 22:851-61. 2015
    ....
  7. pmc Genetic overlap between diagnostic subtypes of ischemic stroke
    Elizabeth G Holliday
    From the School of Medicine and Public Health E G H, J A, School of Biomedical Sciences and Pharmacy L F L, R J S, and School of Nursing and Midwifery J M M, University of Newcastle, Australia Clinical Research Design, IT and Statistical Support Unit, Public Health Research Program, Hunter Medical Research Institute, Newcastle, Australia E G H, C O, J A Department of Clinical Neurosciences, University of Cambridge, UK M T, S B, H S M Institute for Stroke and Dementia Research, Klinikum der Universität Mün chen, Ludwig Maximilians Universitat, Munich, Germany R M, M D Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA G F, J R Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA G F, J R Clinical Trial Service Unit and Epidemiological Studies Unit J C H, R C and Stroke Prevention Research Unit, Nuffield Department of Clinical Neuroscience P M R, University of Oxford, UK Department of Medicine Y C C, B D M and Department of Neurology J W C
    Stroke 46:615-9. 2015
    ..We assessed evidence for a shared genetic basis among the 3 major subtypes: large artery atherosclerosis (LAA), cardioembolism, and small vessel disease (SVD), to inform potential cross-subtype analyses...
  8. pmc Confirmation of childhood acute lymphoblastic leukemia variants, ARID5B and IKZF1, and interaction with parental environmental exposures
    Tiffany Jane Evans
    Centre for Bioinformatics, Biomarker Discovery and Information Based Medicine, Hunter Medical Research Institute, Newcastle, New South Wales, Australia School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia
    PLoS ONE 9:e110255. 2014
    ..If interaction of folic acid supplementation and IKZF1 variants holds, it may be useful to quantify folate levels prior to initiating use of folic acid supplements...
  9. pmc STaRRRT: a table of short tandem repeats in regulatory regions of the human genome
    Katherine A Bolton
    Centre for Information Based Medicine, Hunter Medical Research Institute, Newcastle, NSW, Australia
    BMC Genomics 14:795. 2013
    ..To study STRs located in regulatory regions, we have performed genome-wide analysis to identify all STRs present in a region that is 2 kilobases upstream and 1 kilobase downstream of the transcription start sites of genes...
  10. pmc Continuing difficulties in interpreting CNV data: lessons from a genome-wide CNV association study of Australian HNPCC/lynch syndrome patients
    Bente A Talseth-Palmer
    School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, NSW, Australia
    BMC Med Genomics 6:10. 2013
    ..The aim of the current study was to use SNP-array technology to identify genomic aberrations which could contribute to the increased risk of cancer in HNPCC/LS patients...
  11. pmc Identification of sialyltransferase 8B as a generalized susceptibility gene for psychotic and mood disorders on chromosome 15q25-26
    Erica Z McAuley
    Psychiatric Genetics, Neuroscience Research Australia, Sydney, New South Wales, Australia
    PLoS ONE 7:e38172. 2012
    ....
  12. doi request reprint Sifting the wheat from the chaff: prioritizing GWAS results by identifying consistency across analytical methods
    Christopher Oldmeadow
    School of Medicine and Public Health, University of Newcastle, Newcastle upon Tyne, United Kingdom
    Genet Epidemiol 35:745-54. 2011
    ..We propose that consistency between different analysis methods may be an alternative to increasingly larger sample sizes in sifting true signals from noise in GWAS...
  13. pmc Short sleep duration is associated with risk of future diabetes but not cardiovascular disease: a prospective study and meta-analysis
    Elizabeth G Holliday
    Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health and Hunter Medical Research Institute, University of Newcastle, Newcastle, New South Wales, Australia
    PLoS ONE 8:e82305. 2013
    ..33 [1.20-1.48]). Obtaining less than 6 hours of sleep each night (compared to 7 hours) may increase type 2 diabetes risk by approximately 30%...