J R Ellis
Affiliation: University of Melbourne
- Relationship between nicotinic receptors and cognitive function in early Alzheimer's disease: a 2-[18F]fluoro-A-85380 PET studyJ R Ellis
Department of Nuclear Medicine and Centre for PET, Austin Hospital, 145 Studley Road, Heidelberg, Victoria 3084, Australia
Neurobiol Learn Mem 90:404-12. 2008..It is possible that while the clinical 2-FA PET method described here may be insensitive in detecting changes in early AD, such changes may be detected in more advanced stages of the illness...
- Galantamine-induced improvements in cognitive function are not related to alterations in alpha(4)beta (2) nicotinic receptors in early Alzheimer's disease as measured in vivo by 2-[18F]fluoro-A-85380 PETJ R Ellis
School of Psychology, Psychiatry, and Psychological Medicine, Monash University, Melbourne, Victoria, Australia
Psychopharmacology (Berl) 202:79-91. 2009..e., galantamine) that potentiate cholinergic neurotransmission improve cognitive function in Alzheimer's disease (AD); however, the relationship between these effects and associated changes in nAChRs are yet to be established in vivo...
- The relationship between nicotinic receptors and cognitive functioning in healthy aging: An in vivo positron emission tomography (PET) study with 2-[(18)F]fluoro-A-85380J R Ellis
Monash University, Victoria, Australia
Synapse 63:752-63. 2009..However, this approach may be appropriate for use in pathologies considered to undergo extensive nAChR loss such as Alzheimer's disease and Parkinson's disease...
- Evidence for synergistic modulation of early information processing by nicotinic and muscarinic receptors in humansF F Erskine
Neuropsychopharmacology Laboratory, Brain Sciences Institute, Swinburne University, Melbourne, Australia
Hum Psychopharmacol 19:503-9. 2004..These findings suggest that functional abnormalities in both nicotinic and muscarinic systems may underlie deficits in early visual information processing seen in disorders such as Alzheimer's disease and schizophrenia...