Peter R Ebeling

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. ncbi request reprint Building healthy bones throughout life: an evidence-informed strategy to prevent osteoporosis in Australia
    Peter R Ebeling
    NorthWest Academic Centre, University of Melbourne, and Western Health, Melbourne, Vic, Australia
    Med J Aust 199:S1. 2013
  2. pmc Associations between socioeconomic status and primary total knee joint replacements performed for osteoarthritis across Australia 2003-10: data from the Australian Orthopaedic Association National Joint Replacement Registry
    Sharon L Brennan
    School of Medicine, Deakin University, Geelong, Australia
    BMC Musculoskelet Disord 15:356. 2014
  3. doi request reprint Osteoporosis in men
    Peter R Ebeling
    Department of Endocrinology, Australian Institute of Musculoskeletal Science, North West Academic Centre, University of Melbourne, Western Health, Victoria, Australia
    Curr Opin Rheumatol 25:542-52. 2013
  4. pmc Efficacy and safety of vertebroplasty for treatment of painful osteoporotic vertebral fractures: a randomised controlled trial [ACTRN012605000079640]
    Rachelle Buchbinder
    Monash Department of Clinical Epidemiology, Cabrini Hospital, 183 Wattletree Rd, Malvern Victoria, Australia
    BMC Musculoskelet Disord 9:156. 2008
  5. pmc What is the clinical and ethical importance of incidental abnormalities found by knee MRI?
    Rebecca Grainger
    Department of Medicine, Wellington School of Medicine, University of Otago, 23A Mein St, Newtown, Wellington South 6021, New Zealand
    Arthritis Res Ther 10:R18. 2008
  6. doi request reprint Approach to the patient with transplantation-related bone loss
    Peter R Ebeling
    Department of Medicine Royal Melbourne Hospital Western Hospital and Endocrinology, The University of Melbourne, Western Hospital, Gordon Street, Footscray 3011, Victoria, Australia
    J Clin Endocrinol Metab 94:1483-90. 2009
  7. ncbi request reprint Routine screening for vitamin D deficiency in early pregnancy: past its due date?
    Peter R Ebeling
    Med J Aust 194:332-3. 2011
  8. doi request reprint Clinical practice. Osteoporosis in men
    Peter R Ebeling
    Department of Medicine, Royal Melbourne Hospital Western Hospital, and University of Melbourne, Western Hospital, Melbourne, Victoria, Australia
    N Engl J Med 358:1474-82. 2008
  9. doi request reprint Androgens and osteoporosis
    Peter R Ebeling
    Department of Medicine RMH WH, The University of Melbourne, Western Hospital, Footscray, Victoria, Australia
    Curr Opin Endocrinol Diabetes Obes 17:284-92. 2010
  10. ncbi request reprint Transplantation osteoporosis
    Peter R Ebeling
    Department of Medicine RMH WH, University of Melbourne, Western Hospital, Footscray Vic 3011, Australia
    Curr Osteoporos Rep 5:29-37. 2007

Detail Information

Publications87

  1. ncbi request reprint Building healthy bones throughout life: an evidence-informed strategy to prevent osteoporosis in Australia
    Peter R Ebeling
    NorthWest Academic Centre, University of Melbourne, and Western Health, Melbourne, Vic, Australia
    Med J Aust 199:S1. 2013
    ....
  2. pmc Associations between socioeconomic status and primary total knee joint replacements performed for osteoarthritis across Australia 2003-10: data from the Australian Orthopaedic Association National Joint Replacement Registry
    Sharon L Brennan
    School of Medicine, Deakin University, Geelong, Australia
    BMC Musculoskelet Disord 15:356. 2014
    ..We examine associations between socioeconomic status (SES) and TKR performed for diagnosed osteoarthritis 2003-10 for all Australian males and females aged ≥ 30 yr...
  3. doi request reprint Osteoporosis in men
    Peter R Ebeling
    Department of Endocrinology, Australian Institute of Musculoskeletal Science, North West Academic Centre, University of Melbourne, Western Health, Victoria, Australia
    Curr Opin Rheumatol 25:542-52. 2013
    ..Timely diagnosis and treatment of osteoporosis in men are therefore critical. Secondary causes for osteoporosis are common and need to be excluded. Absolute fracture risk assessment guides selection of men for anti-osteoporotic therapy...
  4. pmc Efficacy and safety of vertebroplasty for treatment of painful osteoporotic vertebral fractures: a randomised controlled trial [ACTRN012605000079640]
    Rachelle Buchbinder
    Monash Department of Clinical Epidemiology, Cabrini Hospital, 183 Wattletree Rd, Malvern Victoria, Australia
    BMC Musculoskelet Disord 9:156. 2008
    ....
  5. pmc What is the clinical and ethical importance of incidental abnormalities found by knee MRI?
    Rebecca Grainger
    Department of Medicine, Wellington School of Medicine, University of Otago, 23A Mein St, Newtown, Wellington South 6021, New Zealand
    Arthritis Res Ther 10:R18. 2008
    ..The prevalence of incidental, potentially clinically significant abnormalities identified by MRI and their clinical significance in a population undergoing knee MRI in research studies are unknown...
  6. doi request reprint Approach to the patient with transplantation-related bone loss
    Peter R Ebeling
    Department of Medicine Royal Melbourne Hospital Western Hospital and Endocrinology, The University of Melbourne, Western Hospital, Gordon Street, Footscray 3011, Victoria, Australia
    J Clin Endocrinol Metab 94:1483-90. 2009
    ..Active vitamin D metabolites may have additional benefits in reducing hyperparathyroidism, particularly after kidney transplantation...
  7. ncbi request reprint Routine screening for vitamin D deficiency in early pregnancy: past its due date?
    Peter R Ebeling
    Med J Aust 194:332-3. 2011
  8. doi request reprint Clinical practice. Osteoporosis in men
    Peter R Ebeling
    Department of Medicine, Royal Melbourne Hospital Western Hospital, and University of Melbourne, Western Hospital, Melbourne, Victoria, Australia
    N Engl J Med 358:1474-82. 2008
  9. doi request reprint Androgens and osteoporosis
    Peter R Ebeling
    Department of Medicine RMH WH, The University of Melbourne, Western Hospital, Footscray, Victoria, Australia
    Curr Opin Endocrinol Diabetes Obes 17:284-92. 2010
    ..Osteoporosis in men is an important public health problem. An improved understanding of the role of androgens in the pathophysiology of bone loss will lead to new treatments...
  10. ncbi request reprint Transplantation osteoporosis
    Peter R Ebeling
    Department of Medicine RMH WH, University of Melbourne, Western Hospital, Footscray Vic 3011, Australia
    Curr Osteoporos Rep 5:29-37. 2007
    ..Large, multicenter treatment trials with oral or parenteral bisphosphonates and calcitriol are recommended...
  11. ncbi request reprint Idiopathic or hypogonadal osteoporosis in men: current and future treatment options
    Peter R Ebeling
    Department of Diabetes and Endocrinology, The University of Melbourne, The Royal Melbourne Hospital, Parkville, Victoria 3050, Australia
    Treat Endocrinol 3:381-91. 2004
    ..In the future, selective androgen receptor modulating drugs may be useful in the prevention and treatment of osteoporosis, and in increasing lean body mass in men, without having adverse effects on prostate and breast tissue...
  12. doi request reprint Serum 25-hydroxyvitamin D deficiency and the 5-year incidence of CKD
    Matthew J Damasiewicz
    Department of Nephrology, Monash Medical Centre, Melbourne, Australia
    Am J Kidney Dis 62:58-66. 2013
    ..Low serum 25-hydroxyvitamin D (25[OH]D) levels have been associated with chronic kidney disease in cross-sectional studies. However, this association has not been studied prospectively in a large general population-based cohort...
  13. pmc 25-Hydroxyvitamin D levels and chronic kidney disease in the AusDiab (Australian Diabetes, Obesity and Lifestyle) study
    Matthew J Damasiewicz
    Department of Nephrology, Monash Medical Centre, 246 Clayton Road, Clayton, 3168, Victoria, Australia
    BMC Nephrol 13:55. 2012
    ..We explored the relationship between 25(OH)D levels and prevalent chronic kidney disease (CKD), albuminuria and impaired GFR, in a national, population-based cohort of Australian adults (AusDiab Study)...
  14. doi request reprint Prevalence of vitamin D deficiency and its determinants in Australian adults aged 25 years and older: a national, population-based study
    Robin M Daly
    Centre for Physical Activity and Nutrition Research, School of Exercise and Nutrition Sciences, Deakin University, Melbourne, Australia
    Clin Endocrinol (Oxf) 77:26-35. 2012
    ..This study evaluated the vitamin D status of Australian adults aged ≥25 years and risk factors associated with vitamin D deficiency in this population...
  15. ncbi request reprint 25-Hydroxyvitamin D concentration and all-cause mortality: the Melbourne Collaborative Cohort Study
    Alicia K Heath
    1Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Level 3, 207 Bouverie Street, Melbourne, Victoria 3010, Australia
    Public Health Nutr . 2016
    ..To investigate relationships between mortality and circulating 25-hydroxyvitamin D (25(OH)D), 25-hydroxycholecalciferol (25(OH)D3) and 25-hydroxyergocalciferol (25(OH)D2)...
  16. ncbi request reprint Adiposity assessed by anthropometric measures has a similar or greater predictive ability than dual-energy X-ray absorptiometry measures for abdominal aortic calcification in community-dwelling older adults
    Xianwen Shang
    Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Melbourne Medical School Western Campus, Level 3, 176 Furlong Road, St Albans, Melbourne, Vic, 3021, Australia
    Int J Cardiovasc Imaging 32:1451-1460. 2016
    ..Our findings add to existing evidence that relatively inexpensive and easily obtained anthropometric measures can be clinically useful indicators of atherosclerosis risk...
  17. doi request reprint Frequent walking, but not total physical activity, is associated with increased fracture incidence: a 5-year follow-up of an Australian population-based prospective study (AusDiab)
    Riku Nikander
    Department of Medicine, NorthWest Academic Centre, University of Melbourne, Western Hospital, Melbourne, Australia
    J Bone Miner Res 26:1638-47. 2011
    ..In conclusion, older adults who adhered to the current PA guidelines were not protected against fragility fractures, but more frequent walking was associated with an increased fracture risk...
  18. pmc A Single Dose of Prednisolone as a Modulator of Undercarboxylated Osteocalcin and Insulin Sensitivity Post-Exercise in Healthy Young Men: A Study Protocol
    Itamar Levinger
    Clinical Exercise Science Research Program, Institute of Sport, Exercise and Active Living ISEAL, Victoria University, Melbourne, Australia
    JMIR Res Protoc 5:e78. 2016
    ..In humans, data are supportive, but the studies are mostly cross-sectional. Exercise increases whole-body insulin sensitivity, in part via ucOC, while acute glucocorticoid treatment suppresses ucOC in humans and mice...
  19. doi request reprint Association of Polymorphisms in MACRO Domain Containing 2 With Thyroid-Associated Orbitopathy
    Jwu Jin Khong
    Melbourne Clinical School Western Campus Department of Medicine, University of Melbourne, Sunshine Hospital, St Albans, Victoria, Australia 2Orbital, Plastics and Lacrimal Unit, The Royal Victorian Eye and Ear Hospital, Victoria, Australia 3Department of
    Invest Ophthalmol Vis Sci 57:3129-37. 2016
    ..This study aimed to identify loci associated with TO in individuals with Graves' disease, using a genome-wide association scan (GWAS) for the first time to our knowledge in TO...
  20. doi request reprint Proportion of Undercarboxylated Osteocalcin and Serum P1NP Predict Incidence of Myocardial Infarction in Older Men
    Bu B Yeap
    School of Medicine and Pharmacology B B Y, S A P C, C S, G J H, L F, University of Western Australia, Perth, Western Australia, Australia Department of Endocrinology and Diabetes B B Y, Fiona Stanley Hospital, Perth, Western Australia, Australia School of Public Health H A, Curtin University, Perth, Western Australia, Australia PathWest Laboratory Medicine S A P C, E B, J P B, Fiona Stanley, Royal Perth and Sir Charles Gairdner Hospitals, Perth, Western Australia, Australia Department of Medicine P R E, School for Clinical Sciences, Monash University, Melbourne, Victoria, Australia Monash Institute of Medical Research C A A, Prince Henry s Research Institute, Melbourne, Victoria, Australia Department of Cardiology C S, Royal Perth Hospital, Perth, Western Australia, Australia Vascular Biology Unit J G, Queensland Research Centre for Peripheral Vascular Disease, School of Medicine, James Cook University, Queensland, Johannes Gutenberg University Hospital
    J Clin Endocrinol Metab 100:3934-42. 2015
    ..The influence of ucOC distinct from other markers of bone turnover on incidence of cardiovascular events is unclear...
  21. doi request reprint Effects of a targeted multimodal exercise program incorporating high-speed power training on falls and fracture risk factors in older adults: a community-based randomized controlled trial
    Jenny Gianoudis
    NorthWest Academic Centre, University of Melbourne, Western Health, Melbourne, Australia Centre for Physical Activity and Nutrition Research, School of Exercise and Nutrition Sciences, Deakin University, Melbourne, Australia
    J Bone Miner Res 29:182-91. 2014
    ..Although this did not translate into a reduction in the rate of falls, further large-scale trials are needed to evaluate the efficacy of this multimodal approach on reducing falls and fracture...
  22. ncbi request reprint The relative effect of endogenous estradiol and androgens on menopausal bone loss: a longitudinal study
    Janet R Guthrie
    Office for Gender and Health, Department of Psychiatry, University of Melbourne, Royal Melbourne Hospital, Charles Connibere Building, Melbourne, Victoria, Australia
    Osteoporos Int 15:881-6. 2004
    ..The aim of this study was to assess the relative strength of the association of endogenous estradiol and androgens with bone loss at the lumbar spine and femoral neck during the menopausal transition...
  23. ncbi request reprint Dietary protein intake and risk of type 2 diabetes: results from the Melbourne Collaborative Cohort Study and a meta-analysis of prospective studies
    Xianwen Shang
    Australian Institute for Musculoskeletal Science, Melbourne, Australia
    Am J Clin Nutr 104:1352-1365. 2016
    ..Reported associations between protein intake from different sources and type 2 diabetes (T2D) have been inconsistent...
  24. doi request reprint Low Relative Lean Mass is Associated with Increased Likelihood of Abdominal Aortic Calcification in Community-Dwelling Older Australians
    Alexander J Rodríguez
    Bone and Muscle Health Research Group, Department of Medicine, School of Clinical Sciences at Monash Health, Faculty of Medicine, Nursing and Health Sciences, Monash University, Monash Medical Centre, 246 Clayton Road, Clayton, Vic, Australia
    Calcif Tissue Int 99:340-9. 2016
    ..AAC is more prevalent and severe in community-dwelling older adults with low relative muscle mass. Maintaining muscle mass could form part of a broader primary prevention strategy in reducing AAC. ..
  25. doi request reprint Dietary protein from different food sources, incident metabolic syndrome and changes in its components: An 11-year longitudinal study in healthy community-dwelling adults
    Xianwen Shang
    Faculty of Medicine, Dentistry and Health Sciences, Melbourne Medical School Western Precinct, The University of Melbourne, Melbourne, Australia Australian Institute for Musculoskeletal Science, Melbourne, Australia Electronic address
    Clin Nutr . 2016
    ..We aimed to prospectively examine the relationships of protein intakes from animal, plant and major food groups with incident MetS and changes in its components...
  26. pmc Glucose-loading reduces bone remodeling in women and osteoblast function in vitro
    Itamar Levinger
    Clinical Exercise Science Program, Institute of Sport, Exercise and Active Living ISEAL, Victoria University, Melbourne, Australia
    Physiol Rep 4:. 2016
    ..The suppressive effect of glucose on BRMs may be due to impaired osteoblast work and longevity. Whether glucose influences material composition and microstructure remains to be determined. ..
  27. pmc Osteo-cise: strong bones for life: protocol for a community-based randomised controlled trial of a multi-modal exercise and osteoporosis education program for older adults at risk of falls and fractures
    Jenny Gianoudis
    NorthWest Academic Centre, Department of Medicine, University of Melbourne, Western Health, Melbourne, Australia
    BMC Musculoskelet Disord 13:78. 2012
    ..Thus, there is a need to develop evidence-based, safe and acceptable prevention strategies at the population level that target multiple risk factors for fragility fractures to reduce the health and economic burden of the condition...
  28. doi request reprint Higher Dietary Calcium Intakes Are Associated With Reduced Risks of Fractures, Cardiovascular Events, and Mortality: A Prospective Cohort Study of Older Men and Women
    Belal Khan
    NorthWest Academic Centre, The University of Melbourne, Western Health, St Albans, Australia
    J Bone Miner Res 30:1758-66. 2015
    ..70 (95% CI 0.54-0.92, p(trend)  = 0.004). In summary, for older men and women, calcium intakes of up to 1348 (316) mg/d from food were associated with decreased risks for fracture, non-fatal CVD, stroke, and all-cause mortality...
  29. doi request reprint Lack of sustained response to teriparatide in a patient with adult hypophosphatasia
    Claudia Gagnon
    Department of Medicine, University of Melbourne, Western Hospital, Footscray Vic 3011, Australia
    J Clin Endocrinol Metab 95:1007-12. 2010
    ..Experience with teriparatide in HPP is limited...
  30. doi request reprint Environmental, personal, and genetic determinants of response to vitamin D supplementation in older adults
    Mary Waterhouse
    Population Health Division M W, B T, C B, C H, P M W, D C W, R E N, QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia Centre for Research Excellence in Sun and Health B T, P R E, M G K, D C W, R E N, Kelvin Grove, Queensland 4059, Australia Sydney School of Public Health, The University of Sydney B K A, Sydney, New South Wales 2006, Australia Northwest Academic Centre, The University of Melbourne P R E, St Albans, Victoria 3021, Australia Melbourne School of Population and Global Health D R E, The University of Melbourne, Melbourne, Victoria 3010, Australia Cancer Epidemiology Centre D R E, Cancer Council Victoria, Melbourne, Victoria 3004, Australia National Health and Medical Research Council Clinical Trials Centre V G, Sydney Medical School, The University of Sydney, Sweden
    J Clin Endocrinol Metab 99:E1332-40. 2014
    ..We aimed to examine genetic and nongenetic determinants of change in serum 25-hydroxyvitamin D (25(OH)D) after supplementation...
  31. ncbi request reprint Vitamin D and health in adults in Australia and New Zealand: a position statement
    Caryl A Nowson
    Centre for Physical Activity and Nutrition Research, Deakin University, Melbourne, Vic
    Med J Aust 196:686-7. 2012
    ..People in high-risk groups may require higher doses. There is good evidence that vitamin D plus calcium supplementation effectively reduces fractures and falls in older men and women...
  32. doi request reprint Secondary causes of low bone mass in patients with breast cancer: a need for greater vigilance
    G Bruce Mann
    Royal Women s Hospital, Parkville, Victoria, 3052, Australia
    J Clin Oncol 27:3605-10. 2009
    ..An observational study to assess the prevalence of secondary causes of low bone density in patients with breast cancer...
  33. doi request reprint Pathogenesis of thyroid eye disease: review and update on molecular mechanisms
    Jwu Jin Khong
    North West Academic Centre, The University of Melbourne, Western Hospital, St Albans, Victoria, Australia Orbital Plastics and Lacrimal Unit, Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria, Australia Austin Health, Department of Surgery, University of Melbourne, Heidelberg, Victoria, Australia
    Br J Ophthalmol 100:142-50. 2016
    ..Further studies in signalling networks and molecular triggers leading to burnout of TO will further our understanding of TO. ..
  34. doi request reprint Changes in gait performance over several years are associated with recurrent falls status in community-dwelling older women at high risk of fracture
    David Scott
    NorthWest Academic Centre, The University of Melbourne and Western Health, St Albans, Victoria, Australia Australian Institute for Musculoskeletal Science, St Albans, Victoria, Australia
    Age Ageing 44:287-93. 2015
    ..It is presently unclear how changes in gait over several years influence risk of recurrent falls in older adults...
  35. doi request reprint Shining the light on Sunshine: a systematic review of the influence of sun exposure on type 2 diabetes mellitus-related outcomes
    Catherine Shore-Lorenti
    NorthWest Academic Centre, Department of Medicine, Western Health, The University of Melbourne, Melbourne, Vic, Australia
    Clin Endocrinol (Oxf) 81:799-811. 2014
    ..This review highlights significant gaps in research pertaining to sun exposure and T2DM-related outcomes. Further research is encouraged as we aim to identify novel preventative strategies for T2DM. ..
  36. doi request reprint Effect of vitamin D supplementation on antibiotic use: a randomized controlled trial
    Bich Tran
    Population Health Department, Queensland Institute of Medical Research, Brisbane, Queensland, Australia BT, DCW, PMW, and REN the Centre for Research Excellence in Sun and Health, Queensland University of Technology, Kelvin Grove, Queensland, Australia BT, MGK, DCW, and REN the School of Population Health, University of Queensland, Brisbane, Queensland, Australia JCvdP the Sydney School of Public Health BKA and the National Health and Medical Research Council of Australia Clinical Trials Centre, Sydney Medical School VG, University of Sydney, Camperdown, New South Wales, Australia Northwest Academic Centre, University of Melbourne, and Western Health, Melbourne, Victoria, Australia PRE the School of Population Health, University of Melbourne, Parkville, Victoria, Australia DRE the AusSun Research Laboratory, Queensland University of Technology, Kelvin Grove, Queensland, Australia MGK and the Menzies Research Institute Tasmania, Hobart, Tasmania, Australia AV
    Am J Clin Nutr 99:156-61. 2014
    ..Observational data suggested that supplementation with vitamin D could reduce risk of infection, but trial data are inconsistent...
  37. pmc Effects of combined calcium and vitamin D supplementation on insulin secretion, insulin sensitivity and β-cell function in multi-ethnic vitamin D-deficient adults at risk for type 2 diabetes: a pilot randomized, placebo-controlled trial
    Claudia Gagnon
    Department of Medicine, NorthWest Academic Centre, The University of Melbourne, Western Health, Melbourne, Australia
    PLoS ONE 9:e109607. 2014
    ..To examine whether combined vitamin D and calcium supplementation improves insulin sensitivity, insulin secretion, β-cell function, inflammation and metabolic markers...
  38. doi request reprint Undercarboxylated osteocalcin, muscle strength and indices of bone health in older women
    Itamar Levinger
    Institute of Sport, Exercise and Active Living ISEAL, College of Sport and Exercise Science, Victoria University, Melbourne, Australia Australian Institute of Musculoskeletal Science, NorthWest Academic Centre, The University of Melbourne, Western Health, St Albans, Australia Electronic address
    Bone 64:8-12. 2014
    ..These data support a role for ucOC in musculoskeletal interactions in humans. Whilst tOC is associated with bone health, ucOC% and ucOC may also be linked to falls and fracture risk by influencing muscle function...
  39. ncbi request reprint Decreased spinal and femoral neck volumetric bone mineral density (BMD) in men with primary osteoporosis and their first-degree male relatives: familial effect on BMD in men
    Bircan Erbas
    Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, University of Melbourne, Parkville, Australia
    Clin Endocrinol (Oxf) 66:78-84. 2007
    ..The purpose of this study was to examine differences in bone volume and volumetric bone mineral density (vBMD) in men with primary osteoporosis and their first-degree male relatives (FDMR)...
  40. doi request reprint Is high dose vitamin D harmful?
    Kerrie M Sanders
    Department of Medicine, Western Health, NorthWest Academic Centre, University of Melbourne, PO Box 294, St Albans, Vic, 3021, Australia
    Calcif Tissue Int 92:191-206. 2013
    ..The current dilemma of defining vitamin D insufficiency and identifying safe and efficacious repletion regimens needs to be resolved...
  41. doi request reprint Social determinants of bone densitometry uptake for osteoporosis risk in patients aged 50yr and older: a systematic review
    Sharon L Brennan
    Department of Medicine, NorthWest Academic Centre, The University of Melbourne, Sunshine Hospital, St Albans, Victoria, Australia
    J Clin Densitom 15:165-75. 2012
    ....
  42. ncbi request reprint Efficacy and safety of oral continuous low-dose versus short-term high-dose vitamin D: a prospective randomised trial conducted in a clinical setting
    Kathryn L Hackman
    Department of Medicine, University of Melbourne, Melbourne, Vic, Australia
    Med J Aust 192:686-9. 2010
    ..The primary end points were the change in serum 25-hydroxyvitamin D (25(OH)D) concentrations at 3 months and the development of hypercalcaemia and hypercalciuria...
  43. ncbi request reprint When continuity of care breaks down: a systems failure in identification of osteoporosis risk in older patients treated for minimal trauma fractures
    Anne Maree Kelly
    Joseph Epstein Centre for Emergency Medicine Research, Western Health, Melbourne, Vic
    Med J Aust 188:389-91. 2008
    ..Our aim was to determine the proportion of patients who underwent bone density testing for osteoporosis of those with a minimal trauma wrist fracture treated in the emergency department (ED)...
  44. doi request reprint A sample preparation protocol for 1H nuclear magnetic resonance studies of water-soluble metabolites in blood and urine
    John R Sheedy
    Department of Medicine, Royal Melbourne and Western Hospitals, University of Melbourne, Footscray, Victoria 3011, Australia
    Anal Biochem 398:263-5. 2010
    ..The efficacy of this protocol was tested using a bovine serum albumin/metabolite mix and human serum samples. This sample preparation method can be readily applied to any protein-containing biofluid for (1)H NMR studies...
  45. pmc A randomised controlled trial of low-dose aspirin for the prevention of fractures in healthy older people: protocol for the ASPREE-Fracture substudy
    Anna L Barker
    Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia
    Inj Prev 22:297-301. 2016
    ..This paper describes the rationale and design of the ASPirin in Reducing Events in the Elderly (ASPREE)-Fracture substudy, which aims to determine whether daily low-dose aspirin decreases fracture risk in healthy older people...
  46. doi request reprint Risk Factors for Graves' Orbitopathy; the Australian Thyroid-Associated Orbitopathy Research (ATOR) Study
    Jwu Jin Khong
    NorthWest Academic Centre J J K, C D S, The University of Melbourne, St Albans, 3021, Victoria, Australia Department of Ophthalmology J J K, Department of Surgery, The University of Melbourne, Heidelberg, 3081 Victoria, Australia Orbital, Plastics and Lacrimal Unit J J K, The Royal Victorian Eye and Ear Hospital, East Melbourne, 3002 Victoria, Australia School of Mathematics and Statistics S F, University of Melbourne, Parkville, 3052 Victoria, Australia Department of Ophthalmology S R, J E C, Flinders University of South Australia, Flinders Medical Centre, Bedford Park, 5042 South Australia, Australia South Australian Institute of Ophthalmology D S, University of Adelaide, Adelaide, 5000 South Australia, Australia and Department of Medicine P R E, School of Clinical Sciences, Monash University, Clayton, 3168 Victoria, Australia
    J Clin Endocrinol Metab 101:2711-20. 2016
    ..Previous association studies suggest the development of Graves' orbitopathy (GO) is variably influenced by environmental risk factors...
  47. doi request reprint Vitamin D deficiency is common in HIV-infected southern Australian adults
    Karen M Klassen
    Department of Medicine, University of Melbourne, Western Health, Melbourne, Victoria, Australia
    Antivir Ther 21:117-25. 2016
    ..It is unknown whether HIV infection is a risk factor for vitamin D deficiency. The aim of the study was to determine whether vitamin D deficiency is more common in HIV-infected than in HIV-uninfected individuals...
  48. ncbi request reprint Vitamin D Deficiency May Be Associated with a More Rapid Decline in CD4 Cell Count to <350 Cells/µL in Untreated HIV-Infected Adults
    Karen M Klassen
    Department of Medicine, University of Melbourne, Level 3, North West Academic Centre, 176 Furlong Road, St Albans VIC 3021, Australia
    Curr HIV Res 13:517-23. 2015
    ..We therefore evaluated effects of vitamin D deficiency (serum 25-hydroxyvitamin D [25(OH)D] <50 nmol/L) on the decline in CD4 cell count in people with HIV not receiving ART...
  49. doi request reprint Fall and Fracture Risk in Sarcopenia and Dynapenia With and Without Obesity: the Role of Lifestyle Interventions
    David Scott
    Department of Medicine, School of Clinical Sciences at Monash Health, Faculty of Medicine, Nursing and Health Sciences, Monash Medical Centre, Monash University, 246 Clayton Road, Clayton, Vic, Australia, 3168
    Curr Osteoporos Rep 13:235-44. 2015
    ....
  50. doi request reprint Dietary α-Linolenic Acid and Total ω-3 Fatty Acids Are Inversely Associated with Abdominal Aortic Calcification in Older Women, but Not in Older Men
    Xianwen Shang
    Faculty of Medicine, Dentistry, and Health Sciences, University of Melbourne, Melbourne Medical School Western Campus, Melbourne, Australia Australian Institute for Musculoskeletal Science, Melbourne, Australia
    J Nutr 145:1778-86. 2015
    ..Associations of α-linolenic acid (ALA), eicosapentaenoic acid (EPA) plus decosahexaenoic acid (DHA), and total omega-3 (n-3) fatty acid (FA) intakes with abdominal aortic calcification (AAC) are not well understood...
  51. pmc Serum 25-hydroxyvitamin D, calcium intake, and risk of type 2 diabetes after 5 years: results from a national, population-based prospective study (the Australian Diabetes, Obesity and Lifestyle study)
    Claudia Gagnon
    Department of Medicine, NorthWest Academic Centre, The University of Melbourne, Western Hospital, Melbourne, Australia
    Diabetes Care 34:1133-8. 2011
    ..To examine whether serum 25-hydroxyvitamin D (25OHD) and dietary calcium predict incident type 2 diabetes and insulin sensitivity...
  52. ncbi request reprint Suburban clustering of vitamin D deficiency in Melbourne, Australia
    Bircan Erbas
    Centre for Molecular Environmental Genetic Analytic Epidemiology, School of Population Health, University of Melbourne, Carlton, Victoria, Australia
    Asia Pac J Clin Nutr 17:63-7. 2008
    ..Vitamin D status of women with differ-ing age and ethnic distributions residing in other suburbs is unknown...
  53. pmc Pooled genome wide association detects association upstream of FCRL3 with Graves' disease
    Jwu Jin Khong
    Melbourne Medical School Western Campus, Department of Medicine, University of Melbourne, Sunshine Hospital, 176 Furlong Road, St Albans, Vic, 3021, Australia
    BMC Genomics 17:939. 2016
    ..This study aimed to determine if a genome wide association study, using a pooling methodology, could detect genomic loci associated with Graves' disease...
  54. ncbi request reprint Sarcopenia: a potential cause and consequence of type 2 diabetes in Australia's ageing population?
    David Scott
    Monash University, Melbourne, Vic
    Med J Aust 205:329-33. 2016
    ..As some older adults with type 2 diabetes have a poor response to exercise, clinicians must ensure that lifestyle modification programs are appropriately prescribed, regularly monitored and modified if necessary. ..
  55. doi request reprint Associations of Sarcopenic Obesity and Dynapenic Obesity with Bone Mineral Density and Incident Fractures Over 5-10 Years in Community-Dwelling Older Adults
    David Scott
    Department of Medicine, School of Clinical Sciences at Monash Health, Faculty of Medicine, Nursing and Health Sciences, Monash University, Level 5, Block E, Monash Medical Centre, 246 Clayton Road, Clayton, Vic, 3168, Australia
    Calcif Tissue Int 99:30-42. 2016
    ..Sarcopenic and dynapenic obese individuals potentially represent a subset of the obese older adult population who require closer monitoring of bone health during ageing. ..
  56. pmc Osteoporosis in men: its pathophysiology and the role of teriparatide in its treatment
    Claudia Gagnon
    Department of Medicine, The University of Melbourne, Western Hospital, Cnr Eleanor and Marion Streets, Footscray, VIC 3011, Australia
    Clin Interv Aging 3:635-45. 2008
    ..Furthermore, the evidence supporting the efficacy of teriparatide treatment in men with osteoporosis is reviewed and its current role in the management of osteoporosis in men is discussed...
  57. doi request reprint (1)H-NMR analysis of the human urinary metabolome in response to an 18-month multi-component exercise program and calcium-vitamin-D3 supplementation in older men
    John R Sheedy
    a Department of Medicine, NorthWest Academic Centre, Sunshine Hospital, The University of Melbourne, Furlong Road, St Albans, Victoria, Australia, 3021
    Appl Physiol Nutr Metab 39:1294-304. 2014
    ..Measurement of specific urinary exercise biomarkers may provide a basis for monitoring performance and metabolic response to exercise regimes. ..
  58. doi request reprint Sarcopenic obesity and dynapenic obesity: 5-year associations with falls risk in middle-aged and older adults
    David Scott
    NorthWest Academic Centre, The University of Melbourne and Western Health, St Albans, Victoria, Australia Australian Institute of Musculoskeletal Science, St Albans, Victoria, Australia
    Obesity (Silver Spring) 22:1568-74. 2014
    ..To determine whether obesity concurrent with sarcopenia (low muscle mass) or dynapenia (low muscle strength) is associated with increased falls risk in middle-aged and older adults...
  59. doi request reprint Investigating the predictive ability of gait speed and quadriceps strength for incident falls in community-dwelling older women at high risk of fracture
    David Scott
    NorthWest Academic Centre, The University of Melbourne, Western Health, St Albans, Victoria, Australia Electronic address
    Arch Gerontol Geriatr 58:308-13. 2014
    ..Quadriceps strength tests may be an acceptable alternative to gait speed for geriatric assessments of falls risk...
  60. pmc Is excess calcium harmful to health?
    Robin M Daly
    Department of Medicine, The University of Melbourne, Western Hospital, Melbourne 3011, Australia
    Nutrients 2:505-22. 2010
    ....
  61. doi request reprint A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures
    Rachelle Buchbinder
    Monash Department of Clinical Epidemiology, Cabrini Hospital, and Monash University, Malvern, Vic, Australia
    N Engl J Med 361:557-68. 2009
    ..Vertebroplasty has become a common treatment for painful osteoporotic vertebral fractures, but there is limited evidence to support its use...
  62. pmc Associations of Vitamin D with Inter- and Intra-Muscular Adipose Tissue and Insulin Resistance in Women with and without Polycystic Ovary Syndrome
    David Scott
    Department of Medicine, School of Clinical Sciences at Monash Health, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton 3168, Victoria, Australia
    Nutrients 8:. 2016
    ..Higher pre-training 25OHD levels may enhance exercise-induced changes in body composition and insulin resistance in overweight women...
  63. doi request reprint Mild Deficits of Cortical Bone in Young Adults With Klinefelter Syndrome or Anorchia Treated With Testosterone
    Sze Choong Wong
    Developmental Endocrinology Research Group S C W, Royal Hospital for Sick Children, University of Glasgow, Glasgow G5 0UN, United Kingdom Department of Medicine D S, P R E, School of Clinical Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Melbourne, Victoria 3168, Australia Department of Medicine D S, NorthWest Academic Centre, The University of Melbourne, St Albans, Melbourne, Victoria 3021, Australia Hormone Research A L, S T, M Z, Murdoch Children s Research Institute, Melbourne, Parkville, Victoria 3052, Australia and Department of Endocrinology M Z, Royal Children s Hospital, Melbourne, Parkville, Victoria 3052, Australia
    J Clin Endocrinol Metab 100:3581-9. 2015
    ..There are currently no data evaluating volumetric bone mineral density (BMD), bone geometry, and body composition in adults with Klinefelter syndrome (KS) or anorchia who have been treated with T from adolescence...
  64. doi request reprint Differential Gene Expression Profiling of Orbital Adipose Tissue in Thyroid Orbitopathy
    Jwu Jin Khong
    Department of Medicine North West Academic Centre, University of Melbourne, St Albans, Victoria, Australia 2Orbital, Plastics, and Lacrimal Unit, The Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria, Australia
    Invest Ophthalmol Vis Sci 56:6438-47. 2015
    ..We aimed to determine differentially expressed genes relevant to orbital inflammation and orbital fat expansion in thyroid orbitopathy (TO) using microarray gene profiling in a case-control study...
  65. doi request reprint Declining Incidence of Medication-Related Osteonecrosis of the Jaw in Patients With Cancer
    Ie Wen Sim
    Western Campus, Melbourne Medical School I W S, K M S, University of Melbourne, St Albans, Victoria 3021, Australia Department of Endocrinology I W S, Western Health, Melbourne, Victoria 3021, Australia Department of Endocrinology I W S, P R E, Monash Health, Melbourne, Victoria 3168, Australia Institute of Health and Ageing K M S, Australian Catholic University, Melbourne, Victoria 3000, Australia Melbourne Dental School G L B, University of Melbourne, Carlton, Victoria 3053, Australia Department of Haematology J F S, Peter MacCallum Cancer Centre, Melbourne, and University of Melbourne, East Melbourne, Victoria 3002, Australia and Department of Medicine P R E, School of Clinical Sciences, Monash University, Melbourne, Victoria 3168, Australia
    J Clin Endocrinol Metab 100:3887-93. 2015
    ..Medication-related osteonecrosis of the jaw (MRONJ) is an infrequent, but severely debilitating condition. Given the significant morbidity attributable to MRONJ and the challenges associated with its management, prevention is crucial...
  66. doi request reprint Ultraviolet index and location are important determinants of vitamin D status in people with human immunodeficiency virus
    Karen M Klassen
    North West Academic Centre, University of Melbourne, Western Health, St Albans, Vic, Australia Melbourne Sexual Health Centre, Alfred Health, Melbourne, Vic, Australia
    Photochem Photobiol 91:431-7. 2015
    ..Cholesterol, the product of an alternative steroid pathway with a common precursor steroid, modified the effect of antiretroviral therapy on serum 25(OH)D...
  67. doi request reprint Measurements of 25-hydroxyvitamin D concentrations in archived dried blood spots are reliable and accurately reflect those in plasma
    Alicia K Heath
    Centre for Epidemiology and Biostatistics A K H, E J W, D R E, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria 3010, Australia Cancer Epidemiology Centre A K H, E J W, D R E, Cancer Council Victoria, Melbourne, Victoria 3004, Australia Department of Epidemiology and Preventive Medicine E J W, Monash University, Melbourne, Victoria 3004, Australia NorthWest Academic Centre P R E, The University of Melbourne and Western Health, St Albans, Victoria 3021, Australia Queensland Brain Institute D K, D W E, The University of Queensland, St Lucia, Queensland 4072, Australia and Queensland Centre for Mental Health Research D W E, The Park Centre for Mental Health, Wacol, Queensland 4076, Australia
    J Clin Endocrinol Metab 99:3319-24. 2014
    ..Dried blood spots (DBS) are a useful resource for these studies. Consequently, accurate, efficient, and inexpensive assays to quantify 25-hydroxyvitamin D (25OHD) in DBS are required...
  68. doi request reprint The effect of acute exercise on undercarboxylated osteocalcin and insulin sensitivity in obese men
    Itamar Levinger
    Institute of Sport, Exercise and Active Living ISEAL, College of Sport and Exercise Science, Victoria University, Melbourne, Australia Australian Institute of Musculoskeletal Science, NorthWest Academic Centre, The University of Melbourne, Western Health, Melbourne, Australia
    J Bone Miner Res 29:2571-6. 2014
    ..66, p = 0.005). Insulin sensitivity, after acute exercise, is associated with circulating levels of ucOC in obese men. Whether ucOC has a direct effect on skeletal muscle insulin sensitivity after exercise is yet to be determined...
  69. doi request reprint Higher serum undercarboxylated osteocalcin and other bone turnover markers are associated with reduced diabetes risk and lower estradiol concentrations in older men
    Bu B Yeap
    Schools of Medicine and Pharmacology B B Y, S A P C, L F and Surgery P E N and Western Australian Centre for Health and Ageing L F, Centre for Medical Research, University of Western Australia, Perth, Western Australia 6009, Australia Department of Endocrinology and Diabetes B B Y, R G, Fremantle and Fiona Stanley Hospitals, Perth, Western Australia 6160, Australia School of Public Health H A, Curtin University, Perth, Western Australia 6102, Australia PathWest Laboratory Medicine S A P C, J P B, Fremantle, Royal Perth and Sir Charles Gairdner Hospitals, Perth, Western Australia 6160, Australia Department of Medicine P R E, School for Clinical Sciences, Monash University, Melbourne, Victoria 3800, Australia ANZAC Research Institute D J H, University of Sydney, Sydney, New South Wales 2139, Australia Monash Institute of Medical Research C A A, Prince Henry s Research Institute, Melbourne, Victoria 3168, Australia and Department of Medicine M G, Austin Health, University of Melbourne, Melbourne, Victoria, Hospital Universitario Virgen de la Victoria
    J Clin Endocrinol Metab 100:63-71. 2015
    ..We hypothesized that ucOC is associated with diabetes risk and modulates sex hormone concentrations in older men, distinct from other bone turnover markers...
  70. doi request reprint Serum selenium status in Graves' disease with and without orbitopathy: a case-control study
    Jwu Jin Khong
    NorthWest Academic Centre, The University of Melbourne, Western Health, St Albans, Australia Orbital Plastics and Lacrimal Unit, The Royal Victorian Eye and Ear Hospital, East Melbourne, Australia
    Clin Endocrinol (Oxf) 80:905-10. 2014
    ..The study aims to determine whether serum selenium levels are reduced in patients with Graves' disease with orbitopathy (GO) compared with without orbitopathy (GD)...
  71. doi request reprint Vitamin D deficiency and its role in muscle-bone interactions in the elderly
    Kerrie M Sanders
    NorthWest Academic Centre, The University of Melbourne, St Albans, Victoria, Australia, 3021
    Curr Osteoporos Rep 12:74-81. 2014
    ....
  72. ncbi request reprint Central abdominal fat and endogenous hormones during the menopausal transition
    Janet R Guthrie
    Office for Gender and Health, Royal Melbourne Hospital, Victoria, Australia
    Fertil Steril 79:1335-40. 2003
    ..To investigate the effect of endogenous hormone levels on central abdominal fat during the menopausal transition in a population-based cohort of Australian-born women...
  73. pmc Cord blood-derived macrophage-lineage cells rapidly stimulate osteoblastic maturation in mesenchymal stem cells in a glycoprotein-130 dependent manner
    Tania J Fernandes
    NorthWest Academic Centre, Department of Medicine, The University of Melbourne, Victoria, Australia Barwon Biomedical Research, The Geelong Hospital, Geelong, Victoria, Australia
    PLoS ONE 8:e73266. 2013
    ..This supports the notion that eliciting gp130-dependent signals in human MSC would be a useful approach to increase bone formation. ..
  74. doi request reprint Oral health risk factors for bisphosphonate-associated jaw osteonecrosis
    Claudine Tsao
    Oral Health CRC and Melbourne Dental School, University of Melbourne, Melbourne, Australia
    J Oral Maxillofac Surg 71:1360-6. 2013
    ..To investigate the role of oral health, including periodontitis, as a risk factor for bisphosphonate-associated jaw osteonecrosis (ONJ)...
  75. doi request reprint An atypical subtrochanteric femoral fracture from pycnodysostosis: a lesson from nature
    Christopher J Yates
    Endocrinology Unit, University of Melbourne, Western Hospital, Footscray, Victoria, Australia
    J Bone Miner Res 26:1377-9. 2011
    ..Therefore, there should be vigilant monitoring for the development of long-term complications noted to occur in diseases of reduced osteoclast function, including pycnodysostosis, in patients receiving these novel antiresorptive agents...
  76. ncbi request reprint Relationship between bone markers and knee cartilage volume in healthy men
    Yuanyuan Wang
    Department of Epidemiology and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, Australia
    J Rheumatol 32:2200-4. 2005
    ..To determine the relationship between biochemical bone markers and knee cartilage volume and cartilage loss over 2 years; and to investigate whether bone markers are useful to predict the cartilage loss in healthy men...
  77. ncbi request reprint The relationship between body composition and knee cartilage volume in healthy, middle-aged subjects
    Flavia M Cicuttini
    Monash University Medical School, Alfred Hospital, Prahran, Australia
    Arthritis Rheum 52:461-7. 2005
    ..This study examined the effect of measures of body composition on the longitudinal change in tibial cartilage volume...
  78. ncbi request reprint Defective osteoblast function may be responsible for bone loss from the proximal femur despite pamidronate therapy
    Peter R Ebeling
    J Clin Endocrinol Metab 90:4414-6. 2005
  79. ncbi request reprint Editorial: inhibin in bone--new tricks for an old dog
    Peter R Ebeling
    J Clin Endocrinol Metab 91:1669-70. 2006
  80. ncbi request reprint Megadose therapy for vitamin D deficiency
    Peter R Ebeling
    Med J Aust 183:4-5. 2005
  81. ncbi request reprint Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research
    Sundeep Khosla
    J Bone Miner Res 22:1479-91. 2007
    ..This report summarizes the findings and recommendations of the task force...
  82. ncbi request reprint Positive effects of intravenous zoledronic acid on bone remodeling and structure: are different effects on osteoblast activity to other oral bisphosphonates responsible?
    Peter R Ebeling
    J Bone Miner Res 23:2-5. 2008
  83. doi request reprint Randomized controlled trial of the effects of calcium with or without vitamin D on bone structure and bone-related chemistry in elderly women with vitamin D insufficiency
    Kun Zhu
    School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    J Bone Miner Res 23:1343-8. 2008
    ..Vitamin D supplementation adds no extra short-term skeletal benefit to calcium citrate supplementation even in women with vitamin D insufficiency...
  84. ncbi request reprint The effects of soy protein containing isoflavones on lipids and indices of bone resorption in postmenopausal women
    Fabien S Dalais
    Department of Epidemiology and Preventive Medicine, Monash University, The Alfred Hospital, Prahran, Australia
    Clin Endocrinol (Oxf) 58:704-9. 2003
    ..To assess the effect of a dietary soy protein supplement containing isoflavones on lipids and indices of bone resorption in postmenopausal women...
  85. ncbi request reprint Preventing osteoporosis: outcomes of the Australian Fracture Prevention Summit
    Philip N Sambrook
    Med J Aust 176:S1-16. 2002
  86. doi request reprint Oral bisphosphonate-induced osteonecrosis: risk factors, prediction of risk using serum CTX testing, prevention, and treatment
    Sundeep Khosla
    J Oral Maxillofac Surg 66:1320-1; author reply 1321-2. 2008