L A Chahl

Summary

Affiliation: University of Newcastle
Country: Australia

Publications

  1. ncbi request reprint Neurons expressing calcium-binding proteins in the prefrontal cortex in schizophrenia
    Paul A Tooney
    Neuroscience Institute of Schizophrenia and Allied Disorders, Darlinghurst, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 28:273-8. 2004
  2. doi request reprint TRP channels and psychiatric disorders
    Loris A Chahl
    School of Biomedical Science and Pharmacy, University of Newcastle, Newcastle, NSW 2308, Australia
    Adv Exp Med Biol 704:987-1009. 2011
  3. ncbi request reprint TRP's: links to schizophrenia?
    Loris A Chahl
    Centre for Mental Health Studies and Schizophrenia Research Institute, James Fletcher Hospital, University of Newcastle, New South Wales, 2308 Australia
    Biochim Biophys Acta 1772:968-77. 2007
  4. pmc Hydrogen sulphide: an endogenous stimulant of capsaicin-sensitive primary afferent neurons?
    L A Chahl
    School of Biomedical Sciences, University of Newcastle, NSW 2308, Australia
    Br J Pharmacol 142:1-2. 2004
  5. ncbi request reprint Tachykinins and neuropsychiatric disorders
    Loris A Chahl
    School of Biomedical Sciences, University of Newcastle, and Neuroscience Institute of Schizophrenia and Allied Disorders, NSW, Australia
    Curr Drug Targets 7:993-1003. 2006
  6. ncbi request reprint Tachykinin NK1 and NK3 receptors in the prefrontal cortex of the human brain
    P A Tooney
    Neuroscience Institute of Schizophrenia and Allied Disorders and School of Biomedical Sciences, Faculty of Medicine and Health Sciences, The University of Newcastle, Callaghan, New South Wales, Australia
    Clin Exp Pharmacol Physiol 27:947-9. 2000
  7. ncbi request reprint Localisation of tachykinin NK1 and NK3 receptors in the human prefrontal and visual cortex
    P A Tooney
    Neuroscience Institute of Schizophrenia and Allied Disorders and School of Biomedical Sciences, Faculty of Medicine and Health Sciences, The University of, Newcastle, Australia
    Neurosci Lett 283:185-8. 2000
  8. ncbi request reprint The effects of haloperidol treatment on the distribution of NK1 receptor immunoreactive neurons in guinea-pig brain
    Paul A Tooney
    NISAD, Neuroscience Institute of Schizophrenia and Allied Disorders NISAD, Sydney, Australia
    Neurosci Lett 383:155-9. 2005
  9. pmc Intrinsic sensory deprivation induced by neonatal capsaicin treatment induces changes in rat brain and behaviour of possible relevance to schizophrenia
    Penny Newson
    School of Biomedical Sciences, University of Newcastle, Callaghan, NSW, Australia
    Br J Pharmacol 146:408-18. 2005
  10. ncbi request reprint Localization of NK1 and NK3 receptors in guinea-pig brain
    J Yip
    Experimental Pharmacology Unit, School of Biomedical Sciences, Faculty of Medicine and Health Sciences, University of Newcastle, Newcastle, Australia
    Regul Pept 98:55-62. 2001

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Neurons expressing calcium-binding proteins in the prefrontal cortex in schizophrenia
    Paul A Tooney
    Neuroscience Institute of Schizophrenia and Allied Disorders, Darlinghurst, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 28:273-8. 2004
    ....
  2. doi request reprint TRP channels and psychiatric disorders
    Loris A Chahl
    School of Biomedical Science and Pharmacy, University of Newcastle, Newcastle, NSW 2308, Australia
    Adv Exp Med Biol 704:987-1009. 2011
    ..Investigation of TRP channels in psychiatric disorders holds the promise of yielding further understanding of the aetiology of psychiatric disorders and the development of new drug treatments...
  3. ncbi request reprint TRP's: links to schizophrenia?
    Loris A Chahl
    Centre for Mental Health Studies and Schizophrenia Research Institute, James Fletcher Hospital, University of Newcastle, New South Wales, 2308 Australia
    Biochim Biophys Acta 1772:968-77. 2007
    ..Investigation of these links holds the prospect of a new understanding of schizophrenia with resultant therapeutic advances...
  4. pmc Hydrogen sulphide: an endogenous stimulant of capsaicin-sensitive primary afferent neurons?
    L A Chahl
    School of Biomedical Sciences, University of Newcastle, NSW 2308, Australia
    Br J Pharmacol 142:1-2. 2004
    ..present evidence that H(2)S stimulates capsaicin-sensitive primary afferent neurons to release tachykinins in the rat urinary bladder. The possible significance of this finding is discussed in this commentary...
  5. ncbi request reprint Tachykinins and neuropsychiatric disorders
    Loris A Chahl
    School of Biomedical Sciences, University of Newcastle, and Neuroscience Institute of Schizophrenia and Allied Disorders, NSW, Australia
    Curr Drug Targets 7:993-1003. 2006
    ..Thus specific therapeutic strategies may be required to enable NK1 receptor antagonists to be introduced for treatment of neuropsychiatric disorders...
  6. ncbi request reprint Tachykinin NK1 and NK3 receptors in the prefrontal cortex of the human brain
    P A Tooney
    Neuroscience Institute of Schizophrenia and Allied Disorders and School of Biomedical Sciences, Faculty of Medicine and Health Sciences, The University of Newcastle, Callaghan, New South Wales, Australia
    Clin Exp Pharmacol Physiol 27:947-9. 2000
    ..Dots of NK3 receptor immunoreactivity were scattered across all cortical layers. In the white matter, astrocytes and beaded fibres displayed NK3 receptor immunoreactivity, particularly in areas surrounding blood vessels...
  7. ncbi request reprint Localisation of tachykinin NK1 and NK3 receptors in the human prefrontal and visual cortex
    P A Tooney
    Neuroscience Institute of Schizophrenia and Allied Disorders and School of Biomedical Sciences, Faculty of Medicine and Health Sciences, The University of, Newcastle, Australia
    Neurosci Lett 283:185-8. 2000
    ..The NK(3)-LI was more abundant and widespread than the NK(1)-LI. This is the first report of the distribution of the NK(1) receptor in the prefrontal and visual cortex of the human brain by immunohistochemistry...
  8. ncbi request reprint The effects of haloperidol treatment on the distribution of NK1 receptor immunoreactive neurons in guinea-pig brain
    Paul A Tooney
    NISAD, Neuroscience Institute of Schizophrenia and Allied Disorders NISAD, Sydney, Australia
    Neurosci Lett 383:155-9. 2005
    ..Whether these changes are related to the therapeutic effects or to the side effects of haloperidol in individuals with schizophrenia, remains to be determined...
  9. pmc Intrinsic sensory deprivation induced by neonatal capsaicin treatment induces changes in rat brain and behaviour of possible relevance to schizophrenia
    Penny Newson
    School of Biomedical Sciences, University of Newcastle, Callaghan, NSW, Australia
    Br J Pharmacol 146:408-18. 2005
    ..It is concluded that neonatal capsaicin treatment of rats produces brain changes that are similar to those found in brains of subjects with schizophrenia...
  10. ncbi request reprint Localization of NK1 and NK3 receptors in guinea-pig brain
    J Yip
    Experimental Pharmacology Unit, School of Biomedical Sciences, Faculty of Medicine and Health Sciences, University of Newcastle, Newcastle, Australia
    Regul Pept 98:55-62. 2001
    ..The present study revealed that tachykinin receptors are widely distributed in the guinea-pig central nervous system...
  11. doi request reprint Receptor changes in brain tissue of rats treated as neonates with capsaicin
    Katerina Zavitsanou
    Radiopharmaceutical Research Institute, Australian Nuclear Science and Technology Organization ANSTO, Menai, New South Wales, Australia
    J Chem Neuroanat 39:248-55. 2010
    ....
  12. ncbi request reprint Sensitization to morphine withdrawal in guinea-pigs
    Akiko Mizutani
    School of Biomedical Sciences, Faculty of Health, University of Newcastle, Newcastle, NSW 2308, Australia
    Eur J Pharmacol 509:135-43. 2005
    ..It is concluded that sensitization to morphine withdrawal occurs in guinea-pigs...
  13. ncbi request reprint The acute effects of capsaicin on the cardiovascular system
    L A Chahl
    Faculty of Medicine, University of Newcastle, N S W, Australia
    Acta Physiol Hung 69:413-9. 1987
    ..Capsaicin induces complex effects on the cardiovascular system, the nature of which varies with the dose and speed of administration...
  14. ncbi request reprint The effect of clonidine on the naltrexone-induced withdrawal response in morphine-treated guinea-pigs
    Sebastian Jungnickel
    Experimental Pharmacology Unit, School of Biomedical Sciences, University of Newcastle, NSW, Australia
    J Pharm Pharmacol 54:127-32. 2002
    ..In conclusion, the modest effect of clonidine in the present experiments suggests that the efficacy of clonidine in humans undergoing naltrexone-induced opioid withdrawal requires further investigation...
  15. ncbi request reprint Immunohistochemical localisation of the NK1 receptor in the human amygdala: preliminary investigation in schizophrenia
    Judith Weidenhofer
    Neuroscience Institute of Schizophrenia and Allied Disorders, Sydney, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 30:1313-21. 2006
    ....