Christopher C Blyth

Summary

Affiliation: University of Western Australia
Country: Australia

Publications

  1. doi request reprint The effectiveness of influenza vaccination in preventing hospitalisation in children in Western Australia
    Christopher C Blyth
    School of Paediatrics and Child Health, University of Western Australia, Perth, Australia Department of Infectious Diseases, Princess Margaret Hospital for Children, Perth, Australia Department of Microbiology, PathWest Laboratory Medicine WA, Princess Margaret Hospital for Children, Perth, Australia Wesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute, University of Western Australia, Perth, Australia Electronic address
    Vaccine 33:7239-44. 2015
  2. doi request reprint Effectiveness of trivalent flu vaccine in healthy young children
    Christopher C Blyth
    School of Paediatrics and Child Health and Princess Margaret Hospital for Children, Perth, Australia Telethon Institute of Child Health Research, West Perth, Australia PathWest Laboratory Medicine, Nedlands, Australia
    Pediatrics 133:e1218-25. 2014
  3. doi request reprint The impact of pandemic A(H1N1)pdm09 influenza and vaccine-associated adverse events on parental attitudes and influenza vaccine uptake in young children
    Christopher C Blyth
    School of Paediatrics and Child Health, University of Western Australia, Subiaco, WA, Australia Princess Margaret Hospital for Children, Subiaco, WA, Australia Wesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute, Subiaco, WA, Australia PathWest Laboratory Medicine WA, Nedlands, WA, Australia Electronic address
    Vaccine 32:4075-81. 2014
  4. pmc The impact of bacterial and viral co-infection in severe influenza
    Christopher C Blyth
    Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research ICPMR, Westmead Hospital, Sydney, NSW, Australia
    Influenza Other Respir Viruses 7:168-76. 2013
  5. doi request reprint Chemoprophylaxis of neonatal fungal infections in very low birthweight infants: efficacy and safety of fluconazole and nystatin
    Christopher C Blyth
    School of Paediatrics and Child Health, University of Western Australia, Princess Margaret Hospital for Children, Subiaco, Western Australia, Australia
    J Paediatr Child Health 48:846-51. 2012
  6. doi request reprint Influenza Vaccine Effectiveness and Uptake in Children at Risk of Severe Disease
    Christopher C Blyth
    From the School of Paediatrics and Child Health, University of Western Australia Department of Infectious Diseases, Princess Margaret Hospital for Children Wesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute, University of Western Australia Department of Microbiology, PathWest Laboratory Medicine WA, Princess Margaret Hospital for Children Department of Health, Communicable Disease Control Directorate, Perth, Western Australia, Australia Victorian Infectious Diseases Reference Laboratory, Melbourne, Australia Australian National University, Canberra, Australia School of Pathology and Laboratory Medicine, University of Western Australia Department of Microbiology, QEII Medical Centre, PathWest Laboratory Medicine WA Emergency Department, Princess Margaret Hospital for Children School of Primary, Aboriginal and Rural Health Care, University of Western Australia and Department of General Paediatrics, Princess Margaret Hospital for Children, Perth, Western Australia, Australia
    Pediatr Infect Dis J 35:309-15. 2016
  7. pmc Immunogenicity and clinical effectiveness of the trivalent inactivated influenza vaccine in immunocompromised children undergoing treatment for cancer
    Rishi S Kotecha
    Department of Haematology and Oncology, Princess Margaret Hospital for Children, GPO Box D184, Perth, Western Australia, 6840, Australia
    Cancer Med 5:285-93. 2016
  8. doi request reprint Systematic review and meta-analysis of respiratory viral coinfections in children
    Faye Janice Lim
    Wesfarmers Centre of Vaccine and Infectious Diseases, Telethon Kids Institute, The University of Western Australia, Perth, Western Australia, Australia
    Respirology 21:648-55. 2016
  9. ncbi request reprint Viral Etiology and the Impact of Codetection in Young Children Presenting With Influenza-Like Illness
    Faye J Lim
    Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, University of Western Australia, West Perth
    J Pediatric Infect Dis Soc . 2016
  10. pmc Viral pneumonitis is increased in obese patients during the first wave of pandemic A(H1N1) 2009 virus
    Jen Kok
    Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research, Sydney Institute for Emerging Infections and Biosecurity, University of Sydney, Westmead Hospital, Westmead, New South Wales, Australia
    PLoS ONE 8:e55631. 2013

Collaborators

Detail Information

Publications34

  1. doi request reprint The effectiveness of influenza vaccination in preventing hospitalisation in children in Western Australia
    Christopher C Blyth
    School of Paediatrics and Child Health, University of Western Australia, Perth, Australia Department of Infectious Diseases, Princess Margaret Hospital for Children, Perth, Australia Department of Microbiology, PathWest Laboratory Medicine WA, Princess Margaret Hospital for Children, Perth, Australia Wesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute, University of Western Australia, Perth, Australia Electronic address
    Vaccine 33:7239-44. 2015
    ..We aimed to determine the VE of the southern hemisphere trivalent inactivated influenza vaccine (TIV) in preventing laboratory-confirmed influenza-associated hospitalisation in children...
  2. doi request reprint Effectiveness of trivalent flu vaccine in healthy young children
    Christopher C Blyth
    School of Paediatrics and Child Health and Princess Margaret Hospital for Children, Perth, Australia Telethon Institute of Child Health Research, West Perth, Australia PathWest Laboratory Medicine, Nedlands, Australia
    Pediatrics 133:e1218-25. 2014
    ..The Western Australian Influenza Vaccine Effectiveness Study commenced in 2008 to evaluate a program providing TIV to children aged 6 to 59 months...
  3. doi request reprint The impact of pandemic A(H1N1)pdm09 influenza and vaccine-associated adverse events on parental attitudes and influenza vaccine uptake in young children
    Christopher C Blyth
    School of Paediatrics and Child Health, University of Western Australia, Subiaco, WA, Australia Princess Margaret Hospital for Children, Subiaco, WA, Australia Wesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute, Subiaco, WA, Australia PathWest Laboratory Medicine WA, Nedlands, WA, Australia Electronic address
    Vaccine 32:4075-81. 2014
    ..Uptake of TIV in children <5 years in Western Australia (WA) decreased in 2010 and has remained low. The impact of pandemic A(H1N1)pdm09 and adverse-events on parental attitudes towards vaccination is uncertain...
  4. pmc The impact of bacterial and viral co-infection in severe influenza
    Christopher C Blyth
    Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research ICPMR, Westmead Hospital, Sydney, NSW, Australia
    Influenza Other Respir Viruses 7:168-76. 2013
    ..Many questions remain concerning the burden, risk factors and impact of bacterial and viral co-infection in patients with pandemic influenza admitted to the intensive care unit (ICU)...
  5. doi request reprint Chemoprophylaxis of neonatal fungal infections in very low birthweight infants: efficacy and safety of fluconazole and nystatin
    Christopher C Blyth
    School of Paediatrics and Child Health, University of Western Australia, Princess Margaret Hospital for Children, Subiaco, Western Australia, Australia
    J Paediatr Child Health 48:846-51. 2012
    ..To review the use of antifungal chemoprophylaxis to prevent neonatal invasive fungal infections (IFI) in very low birthweight infants (VLBW <1500 g)...
  6. doi request reprint Influenza Vaccine Effectiveness and Uptake in Children at Risk of Severe Disease
    Christopher C Blyth
    From the School of Paediatrics and Child Health, University of Western Australia Department of Infectious Diseases, Princess Margaret Hospital for Children Wesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute, University of Western Australia Department of Microbiology, PathWest Laboratory Medicine WA, Princess Margaret Hospital for Children Department of Health, Communicable Disease Control Directorate, Perth, Western Australia, Australia Victorian Infectious Diseases Reference Laboratory, Melbourne, Australia Australian National University, Canberra, Australia School of Pathology and Laboratory Medicine, University of Western Australia Department of Microbiology, QEII Medical Centre, PathWest Laboratory Medicine WA Emergency Department, Princess Margaret Hospital for Children School of Primary, Aboriginal and Rural Health Care, University of Western Australia and Department of General Paediatrics, Princess Margaret Hospital for Children, Perth, Western Australia, Australia
    Pediatr Infect Dis J 35:309-15. 2016
    ....
  7. pmc Immunogenicity and clinical effectiveness of the trivalent inactivated influenza vaccine in immunocompromised children undergoing treatment for cancer
    Rishi S Kotecha
    Department of Haematology and Oncology, Princess Margaret Hospital for Children, GPO Box D184, Perth, Western Australia, 6840, Australia
    Cancer Med 5:285-93. 2016
    ..All children <10 years of age should receive a two-dose schedule. ..
  8. doi request reprint Systematic review and meta-analysis of respiratory viral coinfections in children
    Faye Janice Lim
    Wesfarmers Centre of Vaccine and Infectious Diseases, Telethon Kids Institute, The University of Western Australia, Perth, Western Australia, Australia
    Respirology 21:648-55. 2016
    ..Our findings suggest that coinfection is not associated with increased clinical severity, but further investigations by pathogen pairs are warranted...
  9. ncbi request reprint Viral Etiology and the Impact of Codetection in Young Children Presenting With Influenza-Like Illness
    Faye J Lim
    Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, University of Western Australia, West Perth
    J Pediatric Infect Dis Soc . 2016
    ..Children with influenza and respiratory syncytial virus were hospitalized most frequently. Routine screening and cohorting are recommended only for those with common respiratory pathogens...
  10. pmc Viral pneumonitis is increased in obese patients during the first wave of pandemic A(H1N1) 2009 virus
    Jen Kok
    Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research, Sydney Institute for Emerging Infections and Biosecurity, University of Sydney, Westmead Hospital, Westmead, New South Wales, Australia
    PLoS ONE 8:e55631. 2013
    ..It is postulated that excess inflammation and cytokine production in obese patients following severe influenza infection leads to viral pneumonitis and/or acute respiratory distress syndrome...
  11. doi request reprint A prospective cohort study assessing the reactogenicity of pertussis and influenza vaccines administered during pregnancy
    Annette K Regan
    Communicable Disease Control Directorate, Western Australia Department of Health, Shenton Park, Western Australia 6008, Australia School of Pathology and Laboratory Medicine, University of Western Australia, Crawley, Western Australia 6008, Australia Electronic address
    Vaccine 34:2299-304. 2016
    ..Pertussis vaccination during pregnancy can prevent 91% of infant infections. In 2015, antenatal pertussis vaccination programs were introduced across Australia...
  12. doi request reprint Clinical associations and prevalence of Scedosporium spp. in Australian cystic fibrosis patients: identification of novel risk factors?
    Christopher C Blyth
    Centre for Infectious Diseases and Microbiology, Westmead Hospital, Westmead, NSW, Australia
    Med Mycol 48:S37-44. 2010
    ..Studies are required to confirm independent risk factors for Scedosporium colonization and to determine its impact on lung disease...
  13. pmc Comparison of a rapid antigen test with nucleic acid testing during cocirculation of pandemic influenza A/H1N1 2009 and seasonal influenza A/H3N2
    Jen Kok
    Centre for Infectious Diseases and Microbiology Laboratory Services, Level 3, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, New South Wales 2145, Australia
    J Clin Microbiol 48:290-1. 2010
    ..4% versus 74.2%, P < 0.001). Nucleic acid tests should be used to detect pandemic influenza virus when rapid antigen tests are negative...
  14. ncbi request reprint Antifungal therapy in infants and children with proven, probable or suspected invasive fungal infections
    Christopher C Blyth
    Centre for Infectious Disease and Microbiology, ICPMR, Westmead Hospital, Darcy Road, Westmead, New South Wales, Australia, 2145
    Cochrane Database Syst Rev 2:CD006343. 2010
    ..Further comparative paediatric antifungal drug trials and epidemiological and pharmacological studies are required highlighting the differences between neonates, children and adults with invasive fungal infections...
  15. pmc Influenza outbreaks during World Youth Day 2008 mass gathering
    Christopher C Blyth
    Westmead Hospital, Sydney, New South Wales, Australia
    Emerg Infect Dis 16:809-15. 2010
    ..Greater flexibility by public health authorities and hospitals is required to appropriately manage and contain these outbreaks...
  16. doi request reprint Pandemic (H1N1) 2009 influenza virus seroconversion rates in HIV-infected individuals
    Jen Kok
    Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, New South Wales, Australia
    J Acquir Immune Defic Syndr 56:91-4. 2011
    ..Neither HIV infection, nor severe immunosuppression, was a significant risk factor for pandemic influenza during the first southern hemisphere pandemic wave...
  17. pmc Fatal mycotic aneurysms due to Scedosporium and Pseudallescheria infection
    Adrian Ong
    Centre for Infectious Diseases and Microbiology, Westmead Hospital, Westmead, New South Wales, Australia
    J Clin Microbiol 49:2067-71. 2011
    ..The thoracoabdominal aorta was affected in one patient, and cerebral vessels were affected in the other. Despite voriconazole therapy and surgical resection, the patients died. Previously reported cases are reviewed...
  18. pmc A prospective cohort study comparing the reactogenicity of trivalent influenza vaccine in pregnant and non-pregnant women
    Annette K Regan
    School or Pathology and Laboratory Medicine, University of Western Australia, 227 Stubbs Terrace Shenton Park, Western Australia, Australia
    BMC Pregnancy Childbirth 15:61. 2015
    ..To investigate this, we compared post-vaccination events self-reported by pregnant women to events reported by non-pregnant women receiving TIV...
  19. pmc Pandemic clinical case definitions are non-specific: multiple respiratory viruses circulating in the early phases of the 2009 influenza pandemic in New South Wales, Australia
    Vigneswary Mala Ratnamohan
    Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, New South Wales, Australia
    Virol J 11:113. 2014
    ..During the early phases of the 2009 pandemic, subjects with influenza-like illness only had laboratory testing specific for the new A(H1N1)pdm09 virus...
  20. doi request reprint Pneumonia and lung infections due to emerging and unusual fungal pathogens
    Sharon C A Chen
    Centre for Infectious Diseases and Microbiology, Westmead Hospital, Westmead, Australia
    Semin Respir Crit Care Med 32:703-16. 2011
    ..Surgical resection of diseased tissue and support of the host immune system are often required to optimize outcomes...
  21. doi request reprint Use of data linkage to investigate the aetiology of acute lower respiratory infection hospitalisations in children
    Hannah C Moore
    Telethon Institute for Child Health Research, Centre for Child Health Research, Schools of Pathology and Laboratory Medicine, University of Western Australia, Perth, Western Australia, Australia
    J Paediatr Child Health 48:520-8. 2012
    ..To document the aetiology of acute lower respiratory infection (ALRI) hospitalisations in Western Australian children by linking population-based laboratory data with hospital morbidity data...
  22. doi request reprint Not just little adults: candidemia epidemiology, molecular characterization, and antifungal susceptibility in neonatal and pediatric patients
    Christopher C Blyth
    Centre for Infectious Diseases and Microbiology, Westmead Hospital, Hawkesbury Road, Westmend, New South Wales 2145, Australia
    Pediatrics 123:1360-8. 2009
    ..The purpose of this work was to identify differences in incidence, risk factors, microbiology, treatment, and clinical outcome of candidemia in neonates, children, and adults that might impact on management...
  23. doi request reprint Influenza epidemiology, vaccine coverage and vaccine effectiveness in children admitted to sentinel Australian hospitals in 2014: the Influenza Complications Alert Network (FluCAN)
    Christopher C Blyth
    School of Paediatrics and Child Health, University of Western Australia, Perth, Australia
    Euro Surveill 21:. 2016
    ..6% , 95% CI: 36.0-98.9%) yet appeared poor against H3N2. In summary, the 2014 southern hemisphere TIV was moderately effective against severe influenza in children. Significant VE was observed against influenza A(H1N1)pdm09. ..
  24. doi request reprint Optimization is required when using linked hospital and laboratory data to investigate respiratory infections
    Faye J Lim
    Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, The University of Western Australia, PO Box 855, West Perth, Western Australia 6872, Australia Electronic address
    J Clin Epidemiol 69:23-31. 2016
    ..We conducted a chart review to validate linked microbiological data...
  25. doi request reprint Using SMS to monitor adverse events following trivalent influenza vaccination in pregnant women
    Annette K Regan
    School of Pathology and Laboratory Medicine, University of Western Australia, Perth, WA, Australia
    Aust N Z J Obstet Gynaecol 54:522-8. 2014
    ..Misperceptions of the safety of TIV in pregnancy have been identified as a major contributor to low vaccination rates. Ongoing safety monitoring with dissemination of results could help improve antenatal influenza vaccine uptake...
  26. pmc Modelling the seasonal epidemics of respiratory syncytial virus in young children
    Hannah C Moore
    Telethon Kids Institute, University of Western Australia, Perth, Australia
    PLoS ONE 9:e100422. 2014
    ..Respiratory syncytial virus (RSV) is a major cause of paediatric morbidity. Mathematical models can be used to characterise annual RSV seasonal epidemics and are a valuable tool to assess the impact of future vaccines...
  27. pmc Influenza outbreak during Sydney World Youth Day 2008: the utility of laboratory testing and case definitions on mass gathering outbreak containment
    Sebastiaan J van Hal
    Centre for Infectious Diseases and Microbiology, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, Sydney, New South Wales, Australia
    PLoS ONE 4:e6620. 2009
    ..However, the utility of these clinical case definitions and laboratory testing in mass gathering outbreaks remains unknown...
  28. doi request reprint Predictors of Outcome in Pediatric Osteomyelitis: Five Years Experience in a Single Tertiary Center
    Andrew C Martin
    From the Department of General Paediatrics, Princess Margaret Hospital for Children, Perth, Australia School of Paediatrics and Child Health, The University of Western Australia, Perth, Australia, Telethon Kids Institute, Perth, Australia Department of Orthopaedic Surgery, Princess Margaret Hospital for Children, Perth, Australia Murdoch Childrens Research Institute, Parkville, Australia Department of Paediatrics, University of Melbourne, Parkville, Australia Department of Paediatrics, Monash University, Clayton, Australia PathWest Laboratory Medicine WA, Princess Margaret Hospital for Children, Perth, Australia and Department of Infectious Diseases, Princess Margaret Hospital for Children, Perth, Australia
    Pediatr Infect Dis J 35:387-91. 2016
    ..Predicting which children will develop complicated osteomyelitis remains a challenge, particularly in developed countries where most patients are discharged home after a relatively short period in hospital...
  29. doi request reprint Antibiotic duration and timing of the switch from intravenous to oral route for bacterial infections in children: systematic review and guidelines
    Brendan J McMullan
    Department of Immunology and Infectious Diseases, Sydney Children s Hospital, Randwick, NSW, Australia School of Women s and Children s Health, University of New South Wales, NSW, Australia
    Lancet Infect Dis 16:e139-52. 2016
    ..We have synthesised recommendations for antibiotic duration and intravenous to oral switch to support clinical decision making and prospective research. ..
  30. doi request reprint Australia-wide Point Prevalence Survey of Antimicrobial Prescribing in Neonatal Units: How Much and How Good?
    Joshua Osowicki
    From the Infectious Diseases Unit, Department of General Medicine, The Royal Children s Hospital Melbourne, Parkville, Victoria, Australia Murdoch Children s Research Institute, Parkville, Victoria, Australia Department of Paediatric Infectious Diseases, Monash Children s Hospital, Clayton, Victoria, Australia Department of Infectious Diseases and Microbiology, The Children s Hospital at Westmead, Westmead, New South Wales, Australia Pharmacy Department, The Children s Hospital at Westmead, Westmead, New South Wales, Australia Infection Management and Prevention Service, Lady Cilento Children s Hospital, South Brisbane, Queensland, Australia Department of Paediatrics, University of Queensland, South Brisbane, Queensland, Australia Mater Pharmacy Services, Mater Health, South Brisbane, Queensland, Australia University of Queensland Centre for Clinical Research, South Brisbane, Queensland, Australia Department of General Paediatrics, Princess Margaret Hospital for Children, Perth, Western Australia, Australia Department of Paediatrics, Royal Darwin Hospital, Darwin, Northern Territory, Japan
    Pediatr Infect Dis J 34:e185-90. 2015
    ..There are limited data on antimicrobial prescribing practices for hospitalized neonates. We aimed to describe antimicrobial use in hospitalized Australian neonatal patients, and to determine its appropriateness...
  31. ncbi request reprint Multidrug-resistant tuberculosis in Western Australia, 1998-2012
    Joshua R Francis
    Western Australia Tuberculosis Control Program, Perth, WA, Australia
    Med J Aust 200:328-32. 2014
    ....
  32. doi request reprint Bacillus cereus bacteremia and multiple brain abscesses during acute lymphoblastic leukemia induction therapy
    Jordan R Hansford
    Department of Hematology and Oncology, Princess Margaret Hospital for Children School of Pediatrics and Child Health University of Western Australia PathWest Department of Pediatric and Adolescent Medicine, Princess Margaret Hospital Telethon Institute for Child Health Research, Centre for Child Health Research, Perth, WA, Australia
    J Pediatr Hematol Oncol 36:e197-201. 2014
    ..Therefore, early consideration for neuroimaging should be given for any neutropenic cancer patient identified with B. cereus bacteremia, in particular those with acute leukemia during induction therapy. ..
  33. pmc Clinical and radiological predictors of outcome for Murray Valley encephalitis
    David J Speers
    Department of Microbiology, PathWest Laboratory Medicine WA, Nedlands, Western Australia, Australia
    Am J Trop Med Hyg 88:481-9. 2013
    ..MRI scans repeated months after acute illness showed destruction of the thalamus and basal ganglia, cortex, or cerebellum. These findings may help clinicians predict the neurological outcome when evaluating patients with MVE...
  34. doi request reprint Point of care testing: diagnosis outside the virology laboratory
    Christopher C Blyth
    Centre for Infectious Diseases and Microbiology Laboratory Services, Westmead Hospital, Sydney, NSW, Australia
    Methods Mol Biol 665:415-33. 2011
    ..The sensitivity, specificity, and turn-around time of available POCTs are included for common conditions including respiratory viral infections (e.g. influenza, RSV) and blood-borne viral infections (e.g. HIV)...