Helle Bielefeldt-Ohmann

Summary

Affiliation: University of Queensland
Country: Australia

Publications

  1. doi request reprint Characterization of non-lethal West Nile Virus (WNV) infection in horses: Subclinical pathology and innate immune response
    Helle Bielefeldt-Ohmann
    Australian Infectious Diseases Research Centre, University of Queensland, Australia School of Veterinary Science, University of Queensland, Australia School of Chemistry and Molecular Biosciences, University of Queensland, Australia Electronic address
    Microb Pathog 103:71-79. 2016
  2. pmc Safety and immunogenicity of a delta inulin-adjuvanted inactivated Japanese encephalitis virus vaccine in pregnant mares and foals
    Helle Bielefeldt-Ohmann
    School of Veterinary Science, University of Queensland, Gatton Campus, Gatton 4343, QLD, Australia
    Vet Res 45:130. 2014
  3. pmc Natural exposure of horses to mosquito-borne flaviviruses in south-east Queensland, Australia
    Natalie A Prow
    Australian Infectious Diseases Research Centre, University of Queensland, St Lucia, Qld 4078, Australia
    Int J Environ Res Public Health 10:4432-43. 2013
  4. pmc Diversity of Blastocystis subtypes in dogs in different geographical settings
    Wenqi Wang
    School of Veterinary Science, The University of Queensland Gatton Campus, QLD 4343, Australia
    Parasit Vectors 6:215. 2013
  5. pmc Neuro-invasion by a 'Trojan Horse' strategy and vasculopathy during intrauterine flavivirus infection
    Helle Bielefeldt-Ohmann
    School of Veterinary Science, University of Queensland, Queensland, Australia
    Int J Exp Pathol 93:24-33. 2012
  6. pmc The ORF59 DNA polymerase processivity factor homologs of Old World primate RV2 rhadinoviruses are highly conserved nuclear antigens expressed in differentiated epithelium in infected macaques
    A Gregory Bruce
    Center for Childhood Infection and Prematurity Research, Seattle Children s Research Institute, Seattle, WA 98101 1304, USA
    Virol J 6:205. 2009
  7. doi request reprint Monoclonal antibodies specific for the capsid protein of chikungunya virus suitable for multiple applications
    Lucas Y H Goh
    Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, Queensland 4072, Australia
    J Gen Virol 96:507-12. 2015
  8. pmc Kinetics of the West Nile virus induced transcripts of selected cytokines and Toll-like receptors in equine peripheral blood mononuclear cells
    Muhammad Jasim Uddin
    School of Veterinary Science, The University of Queensland, Gatton, QLD, Australia
    Vet Res 47:61. 2016
  9. pmc Experimental West Nile Virus Infection in Rabbits: An Alternative Model for Studying Induction of Disease and Virus Control
    Willy W Suen
    School of Veterinary Science, University of Queensland, Gatton, QLD 4343, Australia
    Pathogens 4:529-58. 2015
  10. doi request reprint Tissue-specific transcription profile of cytokine and chemokine genes associated with flavivirus control and non-lethal neuropathogenesis in rabbits
    Willy W Suen
    School of Veterinary Science, The University of Queensland, Gatton, QLD 4343, Australia Electronic address
    Virology 494:1-14. 2016

Collaborators

Detail Information

Publications22

  1. doi request reprint Characterization of non-lethal West Nile Virus (WNV) infection in horses: Subclinical pathology and innate immune response
    Helle Bielefeldt-Ohmann
    Australian Infectious Diseases Research Centre, University of Queensland, Australia School of Veterinary Science, University of Queensland, Australia School of Chemistry and Molecular Biosciences, University of Queensland, Australia Electronic address
    Microb Pathog 103:71-79. 2016
    ....
  2. pmc Safety and immunogenicity of a delta inulin-adjuvanted inactivated Japanese encephalitis virus vaccine in pregnant mares and foals
    Helle Bielefeldt-Ohmann
    School of Veterinary Science, University of Queensland, Gatton Campus, Gatton 4343, QLD, Australia
    Vet Res 45:130. 2014
    ..Overall, JE-ADVAX™ appears safe and well-tolerated in pregnant mares and young foals and induces protective levels of JEV neutralizing antibodies with partial cross-neutralization of MVEV and WNVKUN. ..
  3. pmc Natural exposure of horses to mosquito-borne flaviviruses in south-east Queensland, Australia
    Natalie A Prow
    Australian Infectious Diseases Research Centre, University of Queensland, St Lucia, Qld 4078, Australia
    Int J Environ Res Public Health 10:4432-43. 2013
    ....
  4. pmc Diversity of Blastocystis subtypes in dogs in different geographical settings
    Wenqi Wang
    School of Veterinary Science, The University of Queensland Gatton Campus, QLD 4343, Australia
    Parasit Vectors 6:215. 2013
    ....
  5. pmc Neuro-invasion by a 'Trojan Horse' strategy and vasculopathy during intrauterine flavivirus infection
    Helle Bielefeldt-Ohmann
    School of Veterinary Science, University of Queensland, Queensland, Australia
    Int J Exp Pathol 93:24-33. 2012
    ....
  6. pmc The ORF59 DNA polymerase processivity factor homologs of Old World primate RV2 rhadinoviruses are highly conserved nuclear antigens expressed in differentiated epithelium in infected macaques
    A Gregory Bruce
    Center for Childhood Infection and Prematurity Research, Seattle Children s Research Institute, Seattle, WA 98101 1304, USA
    Virol J 6:205. 2009
    ..KSHV ORF59 is antigenic in the infected host and is used as a marker for virus activation and replication...
  7. doi request reprint Monoclonal antibodies specific for the capsid protein of chikungunya virus suitable for multiple applications
    Lucas Y H Goh
    Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, Queensland 4072, Australia
    J Gen Virol 96:507-12. 2015
    ..These antibodies may thus represent useful tools for further research, including investigations into the structure and function of CHIKV CP, and as valuable reagents for CHIKV detection in a range of settings. ..
  8. pmc Kinetics of the West Nile virus induced transcripts of selected cytokines and Toll-like receptors in equine peripheral blood mononuclear cells
    Muhammad Jasim Uddin
    School of Veterinary Science, The University of Queensland, Gatton, QLD, Australia
    Vet Res 47:61. 2016
    ..The up-regulation of gene-transcription for selected cytokines, IFNs, TLRs and TLRs-associated molecules suggests their involvement in virus recognition and control of WNV infection in the horse. ..
  9. pmc Experimental West Nile Virus Infection in Rabbits: An Alternative Model for Studying Induction of Disease and Virus Control
    Willy W Suen
    School of Veterinary Science, University of Queensland, Gatton, QLD 4343, Australia
    Pathogens 4:529-58. 2015
    ..Given this similarity to the human and equine disease, immunocompetent rabbits are, therefore, a valuable animal model for investigating various aspects of non-lethal WNV infections. ..
  10. doi request reprint Tissue-specific transcription profile of cytokine and chemokine genes associated with flavivirus control and non-lethal neuropathogenesis in rabbits
    Willy W Suen
    School of Veterinary Science, The University of Queensland, Gatton, QLD 4343, Australia Electronic address
    Virology 494:1-14. 2016
    ..However, the common IFNγ, TNFα and IL6 transcript upregulation in specific lymphoid organs suggest some conserved elements in the response against flaviviruses, unique to all rabbits. ..
  11. pmc Location and pathogenic potential of Blastocystis in the porcine intestine
    Wenqi Wang
    School of Veterinary Science, The University of Queensland, Gatton, Queensland, Australia
    PLoS ONE 9:e103962. 2014
    ..Our findings also support the use of pigs as animal models and may have implications for blastocystosis diagnosis/treatment. ..
  12. pmc Comparison of faecal microbiota in Blastocystis-positive and Blastocystis-negative irritable bowel syndrome patients
    Robyn Nagel
    School of Veterinary Science, The University of Queensland, Gatton Campus, Brisbane, Queensland, 4343, Australia
    Microbiome 4:47. 2016
    ..Differences in the relative abundance of bacteria in these IBS and HC groups were evaluated from phylum to genus level...
  13. pmc Mechanism of West Nile virus neuroinvasion: a critical appraisal
    Willy W Suen
    School of Veterinary Science, University of Queensland, Gatton, QLD, 4343, Australia
    Viruses 6:2796-825. 2014
    ..In this review, a systematic and critical appraisal of the current evidence relevant to the possible mechanism(s) of WNV neuroinvasion is conducted. ..
  14. pmc The insect-specific Palm Creek virus modulates West Nile virus infection in and transmission by Australian mosquitoes
    Sonja Hall-Mendelin
    Public Health Virology, Forensic and Scientific Services, Department of Health, Queensland Government, PO Box 594, Archerfield, 4108, QLD, Australia
    Parasit Vectors 9:414. 2016
    ....
  15. pmc The West Nile virus-like flavivirus Koutango is highly virulent in mice due to delayed viral clearance and the induction of a poor neutralizing antibody response
    Natalie A Prow
    Australian Infectious Diseases Research Centre, The University of Queensland, St Lucia, Queensland, Australia School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, Queensland, Australia
    J Virol 88:9947-62. 2014
    ..These data demonstrate, for the first time, potent neuroinvasive and neurovirulent properties of a WNV-like virus outside lineages I and II...
  16. pmc Commensal Viruses of Mosquitoes: Host Restriction, Transmission, and Interaction with Arboviral Pathogens
    Roy A Hall
    Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia
    Evol Bioinform Online 12:35-44. 2016
    ..This suggests that some ISVs may act as natural regulators of arboviral transmission. We also discuss viral and host factors that may be responsible for their host restriction...
  17. pmc Blastocystis specific serum immunoglobulin in patients with irritable bowel syndrome (IBS) versus healthy controls
    Robyn Nagel
    School of Veterinary Science, The University of Queensland, Gatton Campus, Gatton, QLD, 4343, Australia
    Parasit Vectors 8:453. 2015
    ..We investigated differences in serum immunoglobulin profiles between patients with IBS, both positive and negative for Blastocystis carriage, and healthy controls (HC)...
  18. doi request reprint Increased expression of capsid protein in trans enhances production of single-round infectious particles by West Nile virus DNA vaccine candidate
    Justin A Roby
    Australian Infectious Diseases Research Centre, University of Queensland, Australia School of Chemistry and Molecular Biosciences, University of Queensland, Australia
    J Gen Virol 95:2176-91. 2014
    ..The optimized DNA yielded ~100-fold greater titres of SRIPs than the original construct, thus providing a promising candidate for further vaccine evaluation. ..
  19. doi request reprint Neutralizing monoclonal antibodies to the E2 protein of chikungunya virus protects against disease in a mouse model
    Lucas Y H Goh
    Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, Queensland 4072, Australia
    Clin Immunol 149:487-97. 2013
    ..Given the current shortage of widely available reagents for CHIKV, these specific antibodies will be useful not only in research, but may also provide the basis for new diagnostics and treatments. ..
  20. doi request reprint Molecular epidemiology of Blastocystis in pigs and their in-contact humans in Southeast Queensland, Australia, and Cambodia
    Wenqi Wang
    School of Veterinary Science, The University of Queensland, Gatton, Queensland 4343, Australia Electronic address
    Vet Parasitol 203:264-9. 2014
    ..We conclude that in intensive piggeries, close contact between pigs and their handlers may increase the risks of zoonotic transmission of Blastocystis. ..
  21. doi request reprint Role of Feline Immunodeficiency Virus in Lymphomagenesis--Going Alone or Colluding?
    Sarah Kaye
    Sarah Kaye, BVSC, is a small animal clinician with the Animal Welfare League Qld Inc in The Gold Coast, Queensland, Australia Wenqi Wang, BVSC, PhD, is a postdoctoral fellow affiliated with the School of Veterinary Science at University of Queensland at Gatton in Australia Craig Miller, DVM, is a postdoctoral fellow in the Department of Microbiology, Immunology and Pathology at Colorado State University in FortCollins, Colorado Alicia McLuckie, BVSC, is a PhD candidate in the Faculty of Veterinary Science at the University of Sydney in NSW, Australia, Julia A Beatty, Bsc, BVetMed, PhD, FANZCVs feline med, is a professor in the Faculty of Veterinary Science at the University of Sydney in NSW, Australia Chris K Grant, PhD, DSC, is founder and CEO of Custom Monoclonals International Corp in West Sacramento, California Sue VandeWoude, DVM, MS, DACLAM, is a professor in the Department of Microbiology, Immunology and Pathology at Colorado State University and Associate Dean for Research in the College of Veterinary and Biomedical Sciences at Colorado State University in Fort Collins, Colorado Helle Bielefeldt Ohmann, DVM, PhD, Kentucky 40506-0044
    ILAR J 57:24-33. 2016
    ..Here we review the possible mechanisms involved in FIV lymphomagenesis, including the possible involvement of coinfections, notably those with gamma-herpesviruses. ..
  22. pmc Features of Blastocystis spp. in xenic culture revealed by deconvolutional microscopy
    Robyn Nagel
    School of Veterinary Science, University of Queensland, Gatton, Queensland, Australia
    Parasitol Res 114:3237-45. 2015
    ..Tear-shaped granules were observed exiting from the surface of an amoebic form, but their origin and identity remain unknown...