Daniel T Barratt

Summary

Affiliation: University of Adelaide
Country: Australia

Publications

  1. ncbi request reprint CYP2C8 Genotype Significantly Alters Imatinib Metabolism in Chronic Myeloid Leukaemia Patients
    Daniel T Barratt
    Discipline of Pharmacology, Adelaide Medical School, University of Adelaide, Adelaide, SA, 5005, Australia
    Clin Pharmacokinet . 2016
  2. ncbi request reprint Association between the DRD2 A1 allele and response to methadone and buprenorphine maintenance treatments
    Daniel T Barratt
    Discipline of Pharmacology, School of Medical Sciences, University of Adelaide, Adelaide, South Australia, Australia
    Am J Med Genet B Neuropsychiatr Genet 141:323-31. 2006
  3. ncbi request reprint Pharmacogenetics of opioids
    Andrew A Somogyi
    Discipline of Pharmacology, School of Medical Sciences, University of Adelaide, Adelaide, Australia
    Clin Pharmacol Ther 81:429-44. 2007
  4. ncbi request reprint Ethnicity-dependent influence of innate immune genetic markers on morphine PCA requirements and adverse effects in postoperative pain
    Andrew A Somogyi
    aDiscipline of Pharmacology, School of Medicine, Faculty of Health Sciences, University of Adelaide, Adelaide, South Australia, Australia bDepartment of Clinical Pharmacology, Royal Adelaide Hospital, Adelaide, South Australia, Australia cKK Research Centre, KK Women s and Children s Hospital, Singapore dDepartment of Women s Anesthesia, KK Women s and Children s Hospital, Singapore ePaediatrics Academic Clinical Programme, Singhealth Duke NUS Graduate Medical School, Singapore fDiscipline of Physiology, School of Medicine, Faculty of Health Sciences, University of Adelaide, Adelaide, South Australia, Australia gAustralian Research Council Centre of Excellence for Nanoscale BioPhotonics, University of Adelaide, Adelaide, South Australia, Australia
    Pain 157:2458-2466. 2016
  5. ncbi request reprint ABCB1 genetic variability and methadone dosage requirements in opioid-dependent individuals
    Janet K Coller
    Discipline of Pharmacology, School of Medical Sciences, The University of Adelaide, and Department of Clinical Pharmacology, Royal Adelaide Hospital, SA, Australia
    Clin Pharmacol Ther 80:682-90. 2006
  6. doi request reprint Pharmacogenomics of methadone maintenance treatment
    Andrew A Somogyi
    Discipline of Pharmacology, School of Medical Sciences, Faculty of Health Sciences, University of Adelaide, Adelaide 5005, Australia
    Pharmacogenomics 15:1007-27. 2014
  7. doi request reprint Impact of CYP2C8*3 polymorphism on in vitro metabolism of imatinib to N-desmethyl imatinib
    Muhammad Suleman Khan
    a Discipline of Pharmacology, School of Medical Sciences, University of Adelaide, Adelaide, Australia and
    Xenobiotica 46:278-87. 2016
  8. pmc Innate Immune Signalling Genetics of Pain, Cognitive Dysfunction and Sickness Symptoms in Cancer Pain Patients Treated with Transdermal Fentanyl
    Daniel T Barratt
    Discipline of Pharmacology, School of Medicine, University of Adelaide, Adelaide, Australia Centre for Personalised Cancer Medicine, University of Adelaide, Adelaide, Australia
    PLoS ONE 10:e0137179. 2015
  9. doi request reprint Harnessing pain heterogeneity and RNA transcriptome to identify blood-based pain biomarkers: a novel correlational study design and bioinformatics approach in a graded chronic constriction injury model
    Peter M Grace
    Discipline of Pharmacology, School of Medical Sciences, University of Adelaide, Adelaide, Australia
    J Neurochem 122:976-94. 2012

Detail Information

Publications10

  1. ncbi request reprint CYP2C8 Genotype Significantly Alters Imatinib Metabolism in Chronic Myeloid Leukaemia Patients
    Daniel T Barratt
    Discipline of Pharmacology, Adelaide Medical School, University of Adelaide, Adelaide, SA, 5005, Australia
    Clin Pharmacokinet . 2016
    ..The aims of this study were to determine the effects of the CYP2C8*3 and *4 polymorphisms on imatinib metabolism and plasma imatinib concentrations in chronic myeloid leukaemia (CML) patients...
  2. ncbi request reprint Association between the DRD2 A1 allele and response to methadone and buprenorphine maintenance treatments
    Daniel T Barratt
    Discipline of Pharmacology, School of Medical Sciences, University of Adelaide, Adelaide, South Australia, Australia
    Am J Med Genet B Neuropsychiatr Genet 141:323-31. 2006
    ..This suggests the need for a further prospective investigation into the role of the DRD2 A(1) allele in heroin use and response to maintenance pharmacotherapies for opioid dependence...
  3. ncbi request reprint Pharmacogenetics of opioids
    Andrew A Somogyi
    Discipline of Pharmacology, School of Medical Sciences, University of Adelaide, Adelaide, Australia
    Clin Pharmacol Ther 81:429-44. 2007
    ....
  4. ncbi request reprint Ethnicity-dependent influence of innate immune genetic markers on morphine PCA requirements and adverse effects in postoperative pain
    Andrew A Somogyi
    aDiscipline of Pharmacology, School of Medicine, Faculty of Health Sciences, University of Adelaide, Adelaide, South Australia, Australia bDepartment of Clinical Pharmacology, Royal Adelaide Hospital, Adelaide, South Australia, Australia cKK Research Centre, KK Women s and Children s Hospital, Singapore dDepartment of Women s Anesthesia, KK Women s and Children s Hospital, Singapore ePaediatrics Academic Clinical Programme, Singhealth Duke NUS Graduate Medical School, Singapore fDiscipline of Physiology, School of Medicine, Faculty of Health Sciences, University of Adelaide, Adelaide, South Australia, Australia gAustralian Research Council Centre of Excellence for Nanoscale BioPhotonics, University of Adelaide, Adelaide, South Australia, Australia
    Pain 157:2458-2466. 2016
    ..0007) but not in the Malay or Indian cohorts. Innate immune genetics may contribute to variability in postsurgical opioid requirements in an ethnicity-dependent manner...
  5. ncbi request reprint ABCB1 genetic variability and methadone dosage requirements in opioid-dependent individuals
    Janet K Coller
    Discipline of Pharmacology, School of Medical Sciences, The University of Adelaide, and Department of Clinical Pharmacology, Royal Adelaide Hospital, SA, Australia
    Clin Pharmacol Ther 80:682-90. 2006
    ..This retrospective study aimed to investigate the influence of ABCB1 genetic variability on methadone dose requirements...
  6. doi request reprint Pharmacogenomics of methadone maintenance treatment
    Andrew A Somogyi
    Discipline of Pharmacology, School of Medical Sciences, Faculty of Health Sciences, University of Adelaide, Adelaide 5005, Australia
    Pharmacogenomics 15:1007-27. 2014
    ....
  7. doi request reprint Impact of CYP2C8*3 polymorphism on in vitro metabolism of imatinib to N-desmethyl imatinib
    Muhammad Suleman Khan
    a Discipline of Pharmacology, School of Medical Sciences, University of Adelaide, Adelaide, Australia and
    Xenobiotica 46:278-87. 2016
    ..4. In conclusion, CYP2C8*3 is a gain-of-function polymorphism for imatinib N-demethylation, which appears to be mainly mediated by CYP2C8 and not CYP3A4 in vitro in HLM...
  8. pmc Innate Immune Signalling Genetics of Pain, Cognitive Dysfunction and Sickness Symptoms in Cancer Pain Patients Treated with Transdermal Fentanyl
    Daniel T Barratt
    Discipline of Pharmacology, School of Medicine, University of Adelaide, Adelaide, Australia Centre for Personalised Cancer Medicine, University of Adelaide, Adelaide, Australia
    PLoS ONE 10:e0137179. 2015
    ..This supports the involvement of innate immune signalling in cognitive dysfunction, and identifies MyD88 signalling pathways as a potential focus for predicting and reducing the burden of cognitive dysfunction in cancer pain patients. ..
  9. doi request reprint Harnessing pain heterogeneity and RNA transcriptome to identify blood-based pain biomarkers: a novel correlational study design and bioinformatics approach in a graded chronic constriction injury model
    Peter M Grace
    Discipline of Pharmacology, School of Medical Sciences, University of Adelaide, Adelaide, Australia
    J Neurochem 122:976-94. 2012
    ..Future studies may demonstrate the predictive ability of these biomarker genes across other models and additional variables...