Justin Tan

Summary

Affiliation: The Bionic Ear Institute
Country: Australia

Publications

  1. ncbi request reprint Carbon nanotubes: biocompatibility of immobilized aligned carbon nanotubes (small 8/2011)
    David A X Nayagam
    The Bionic Ear Institute, 384 388 Albert Street, East Melbourne, 3002, Australia
    Small 7:981. 2011
  2. pmc Aminoglycoside-induced degeneration of adult spiral ganglion neurons involves differential modulation of tyrosine kinase B and p75 neurotrophin receptor signaling
    Justin Tan
    Department of Otolaryngology, 32 Gisborne St, East Melbourne, Victoria 3002, Australia
    Am J Pathol 169:528-43. 2006
  3. pmc Cochlear implants stimulate activity-dependent CREB pathway in the deaf auditory cortex: implications for molecular plasticity induced by neural prosthetic devices
    Justin Tan
    The Bionic Ear Institute, East Melbourne, Victoria 3002, Australia
    Cereb Cortex 18:1799-813. 2008
  4. doi request reprint The p75 neurotrophin receptor protects primary auditory neurons against acoustic trauma in mice
    Justin Tan
    The Bionic Ear Institute, 384 388 Albert St, East Melbourne, Victoria 3002, Australia
    Hear Res 268:46-59. 2010
  5. doi request reprint Biocompatibility of immobilized aligned carbon nanotubes
    David A X Nayagam
    The Bionic Ear Institute, 384 388 Albert Street, East Melbourne, 3002, Australia
    Small 7:1035-42. 2011
  6. pmc Improved Auditory Nerve Survival with Nanoengineered Supraparticles for Neurotrophin Delivery into the Deafened Cochlea
    Andrew K Wise
    The Bionics Institute, 384 388 Albert Street, East Melbourne, Melbourne, Australia
    PLoS ONE 11:e0164867. 2016
  7. doi request reprint Early cochlear response and ICAM-1 expression to cochlear implantation
    Gordana Elizabeth Kel
    Department of Otolaryngology, University of Melbourne and Department of Surgery, Monash University, Clayton, Melbourne, Victoria, Australia
    Otol Neurotol 34:1595-602. 2013
  8. doi request reprint Absence of SERPINB6A causes sensorineural hearing loss with multiple histopathologies in the mouse inner ear
    Justin Tan
    Department of Otolaryngology, University of Melbourne, East Melbourne, Australia
    Am J Pathol 183:49-59. 2013
  9. pmc Nanoporous peptide particles for encapsulating and releasing neurotrophic factors in an animal model of neurodegeneration
    Justin Tan
    Bionics Institute, East Melbourne, Victoria 3002, Australia
    Adv Mater 24:3362-6. 2012
  10. pmc Thyroxine treatments do not correct inner ear defects in tmprss1 mutant mice
    Syazana Hanifa
    The Bionic Ear Institute, University of Melbourne, East Melbourne, Victoria, Australia
    Neuroreport 21:897-901. 2010

Collaborators

  • Robert K Shepherd
  • Jun Chen
  • Graeme M Clark
  • Andrew K Wise
  • Jin Xu
  • David A X Nayagam
  • Marlies Knipper
  • Thomas Schimmang
  • Rama Panford-Walsh
  • Lukas Ruttiger
  • Iris Köpschall
  • Karin Rohbock
  • Ulrike Zimmermann
  • Gordana Elizabeth Kel
  • Kylie A Magee
  • Jennifer Irwin
  • Peter Innis
  • Richard A Williams
  • Chris E Williams
  • Sue Finch
  • Ronald T Leung
  • Gordon G Wallace
  • Syazana Hanifa
  • Annette Limberger
  • Marcus Müller
  • Estela Carnicero
  • Hayden Timothy Eastwood
  • Sarin Wongprasartsuk
  • Stephen John O'Leary
  • Hamish S Scott
  • Michel Guipponi
  • Pauline Crewther
  • Hyun Soon Geisler
  • Elmar Oestreicher
  • Saida Hadjab
  • Anna Vieljans
  • Wibke Singer
  • Jürgen Theodor Fraenzer
  • Jelka Cimerman
  • Liliana Minichiello
  • Maria Teresa Alonso

Detail Information

Publications14

  1. ncbi request reprint Carbon nanotubes: biocompatibility of immobilized aligned carbon nanotubes (small 8/2011)
    David A X Nayagam
    The Bionic Ear Institute, 384 388 Albert Street, East Melbourne, 3002, Australia
    Small 7:981. 2011
    ..Collectively, these results suggest that immobilized nanotube structures should be considered for further investigation as bionic components...
  2. pmc Aminoglycoside-induced degeneration of adult spiral ganglion neurons involves differential modulation of tyrosine kinase B and p75 neurotrophin receptor signaling
    Justin Tan
    Department of Otolaryngology, 32 Gisborne St, East Melbourne, Victoria 3002, Australia
    Am J Pathol 169:528-43. 2006
    ..Together, these data suggest that an antagonistic interplay of p75NTR and TrkB receptor signaling, possibly modulated by selective BDNF processing, mediates SGN death in vivo...
  3. pmc Cochlear implants stimulate activity-dependent CREB pathway in the deaf auditory cortex: implications for molecular plasticity induced by neural prosthetic devices
    Justin Tan
    The Bionic Ear Institute, East Melbourne, Victoria 3002, Australia
    Cereb Cortex 18:1799-813. 2008
    ..These findings provide insights into adaptive, molecular mechanisms recruited by the brain upon functional electrical stimulation by neural prosthetic devices...
  4. doi request reprint The p75 neurotrophin receptor protects primary auditory neurons against acoustic trauma in mice
    Justin Tan
    The Bionic Ear Institute, 384 388 Albert St, East Melbourne, Victoria 3002, Australia
    Hear Res 268:46-59. 2010
    ..Therefore, our data do not support a role of p75NTR as a death inducer in PANs but show its crucial role in protecting PANs...
  5. doi request reprint Biocompatibility of immobilized aligned carbon nanotubes
    David A X Nayagam
    The Bionic Ear Institute, 384 388 Albert Street, East Melbourne, 3002, Australia
    Small 7:1035-42. 2011
    ..Collectively, these results suggest that immobilized nanotube structures should be considered for further investigation as bionic components...
  6. pmc Improved Auditory Nerve Survival with Nanoengineered Supraparticles for Neurotrophin Delivery into the Deafened Cochlea
    Andrew K Wise
    The Bionics Institute, 384 388 Albert Street, East Melbourne, Melbourne, Australia
    PLoS ONE 11:e0164867. 2016
    ..003). These data support the clinical potential of this technology particularly as the supraparticles can be loaded with a variety of therapeutic drugs...
  7. doi request reprint Early cochlear response and ICAM-1 expression to cochlear implantation
    Gordana Elizabeth Kel
    Department of Otolaryngology, University of Melbourne and Department of Surgery, Monash University, Clayton, Melbourne, Victoria, Australia
    Otol Neurotol 34:1595-602. 2013
    ..To examine the early cochlear response and intercellular cell adhesion molecule-1 (ICAM-1) expression to implantation of a cochlear electrode into the scala tympani...
  8. doi request reprint Absence of SERPINB6A causes sensorineural hearing loss with multiple histopathologies in the mouse inner ear
    Justin Tan
    Department of Otolaryngology, University of Melbourne, East Melbourne, Australia
    Am J Pathol 183:49-59. 2013
    ..These findings establish these mutant mice as a suitable model system to elucidate how SERPINB6 deficiency causes deafness in humans...
  9. pmc Nanoporous peptide particles for encapsulating and releasing neurotrophic factors in an animal model of neurodegeneration
    Justin Tan
    Bionics Institute, East Melbourne, Victoria 3002, Australia
    Adv Mater 24:3362-6. 2012
    ..Animal experiments demonstrate the released BDNF can efficiently rescue the auditory neurons (as indicated by the arrows) in the cochlea of guinea pigs with sensorineural hearing loss...
  10. pmc Thyroxine treatments do not correct inner ear defects in tmprss1 mutant mice
    Syazana Hanifa
    The Bionic Ear Institute, University of Melbourne, East Melbourne, Victoria, Australia
    Neuroreport 21:897-901. 2010
    ..Both the treatments could not ameliorate hearing loss or correct deformities in the tectorial membrane of these mutant mice, suggesting that a deficiency in tmprss1 affects thyroxine responsiveness in the inner ear in vivo...
  11. ncbi request reprint BDNF mRNA expression and protein localization are changed in age-related hearing loss
    Lukas Ruttiger
    Molecular Neurobiology, Tübingen Hearing Research Center, Department of Otorhinolaryngology, University of Tubingen, Tubingen, Germany
    Neurobiol Aging 28:586-601. 2007
    ..Our results suggest that reduced BDNF protein levels in auditory nerves over age may be a crucial factor in the altered brainstem plasticity observed during presbycusis...
  12. ncbi request reprint Lack of Bdnf and TrkB signalling in the postnatal cochlea leads to a spatial reshaping of innervation along the tonotopic axis and hearing loss
    Thomas Schimmang
    Center for Molecular Neurobiology Hamburg, University of Hamburg, Falkenreid, Hamburg, Germany
    Development 130:4741-50. 2003
    ..Our results indicate a substantial potential for re-innervation processes in the mature cochlea, which may also be of relevance for treatment of hearing loss in humans...
  13. doi request reprint Midazolam reverses salicylate-induced changes in brain-derived neurotrophic factor and arg3.1 expression: implications for tinnitus perception and auditory plasticity
    Rama Panford-Walsh
    Department of Otorhinolaryngology, Universitat Tubingen, Tubingen, Germany
    Mol Pharmacol 74:595-604. 2008
    ..1 and BDNF as markers for activity changes in the auditory system and suggest a role of GABAergic inhibition of cochlear neurons in the modulation of Arg3.1 plasticity changes in the auditory cortex and tinnitus perception...
  14. ncbi request reprint Herpes simplex virus type 1-mediated transfer of neurotrophin-3 stimulates survival of chicken auditory sensory neurons
    Estela Carnicero
    Instituto de Biologia y Genetica Molecular, Universidad de Valladolid y Consejo Superior de Investigaciones Cientificas, Departamento de Bioquimica, Biologia Molecular y Fisiologia, Facultad de Medicina, 47005 Valladolid, Spain
    Neurosci Lett 321:149-52. 2002
    ..Therefore, this vector may present a unique entry point to develop therapies preventing or treating hearing impairment caused by the degeneration of auditory neurons...