Hisatomi Arima

Summary

Affiliation: The George Institute for International Health
Country: Australia

Publications

  1. doi request reprint Blood pressure-lowering treatment for primary and secondary prevention of different types of stroke
    Hisatomi Arima
    George Institute for International Health, University of Sydney and Royal Prince Alfred Hospital, Sydney, PO Box M201, Missenden Road, NSW 2050, Sydney, Australia
    Expert Rev Cardiovasc Ther 7:627-36. 2009
  2. doi request reprint Effects of combination of perindopril, indapamide, and calcium channel blockers in patients with type 2 diabetes mellitus: results from the Action In Diabetes and Vascular Disease: Preterax and Diamicron Controlled Evaluation (ADVANCE) trial
    John Chalmers
    The George Institute for Global Health, PO Box M201, Camperdown, NSW 2050, Australia
    Hypertension 63:259-64. 2014
  3. ncbi request reprint Earlier blood pressure-lowering and greater attenuation of hematoma growth in acute intracerebral hemorrhage: INTERACT pilot phase
    Hisatomi Arima
    The George Institute for Global Health, Royal Prince Alfred Hospital and University of Sydney, Sydney, Australia
    Stroke 43:2236-8. 2012
  4. doi request reprint Effects of perindopril-based lowering of blood pressure on intracerebral hemorrhage related to amyloid angiopathy: the PROGRESS trial
    Hisatomi Arima
    The George Institute for International Health, University of Sydney and The Royal Prince Alfred Hospital, Sydney, Australia
    Stroke 41:394-6. 2010
  5. ncbi request reprint Lower target blood pressures are safe and effective for the prevention of recurrent stroke: the PROGRESS trial
    Hisatomi Arima
    The George Institute for International Health, University of Sydney, Sydney, NSW, Australia
    J Hypertens 24:1201-8. 2006
  6. pmc Current management of intracerebral haemorrhage in China: a national, multi-centre, hospital register study
    Jade W Wei
    The George Institute for Global Health, Royal Prince Alfred Hospital and University of Sydney, Sydney, Australia
    BMC Neurol 11:16. 2011
  7. doi request reprint Effects of early intensive blood pressure-lowering treatment on the growth of hematoma and perihematomal edema in acute intracerebral hemorrhage: the Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT)
    Craig S Anderson
    The George Institute for International Health, Royal Prince Alfred Hospital and the University of Sydney, Sydney, Australia
    Stroke 41:307-12. 2010
  8. doi request reprint Statistical analysis plan for the second INTEnsive blood pressure Reduction in Acute Cerebral hemorrhage Trial (INTERACT2): a large-scale investigation to solve longstanding controversy over the most appropriate management of elevated blood pressure in th
    Craig Anderson
    The George Institute for Global Health, University of Sydney, Royal Prince Alfred Hospital and University of Sydney, Missenden Road, Camperdown, ACT 2050, Australia
    Int J Stroke 8:327-8. 2013
  9. doi request reprint Rapid blood-pressure lowering in patients with acute intracerebral hemorrhage
    Craig S Anderson
    George Institute For Global Health, University of Sydney, Sydney, NSW, Australia
    N Engl J Med 368:2355-65. 2013
  10. doi request reprint Effects of blood pressure lowering on intracranial and extracranial bleeding in patients on antithrombotic therapy: the PROGRESS trial
    Hisatomi Arima
    George Institute For Global Health, PO Box M201, Missenden Road, NSW 2050 Australia
    Stroke 43:1675-7. 2012

Collaborators

Detail Information

Publications60

  1. doi request reprint Blood pressure-lowering treatment for primary and secondary prevention of different types of stroke
    Hisatomi Arima
    George Institute for International Health, University of Sydney and Royal Prince Alfred Hospital, Sydney, PO Box M201, Missenden Road, NSW 2050, Sydney, Australia
    Expert Rev Cardiovasc Ther 7:627-36. 2009
    ..Blood pressure lowering is likely to be one of the most effective and generalizable strategies across a variety of stroke subtypes...
  2. doi request reprint Effects of combination of perindopril, indapamide, and calcium channel blockers in patients with type 2 diabetes mellitus: results from the Action In Diabetes and Vascular Disease: Preterax and Diamicron Controlled Evaluation (ADVANCE) trial
    John Chalmers
    The George Institute for Global Health, PO Box M201, Camperdown, NSW 2050, Australia
    Hypertension 63:259-64. 2014
    ..38). There was no detectable increase in adverse effects in those receiving CCB. The combination of perindopril and indapamide with CCBs seems to provide further protection against mortality in patients with type 2 diabetes mellitus. ..
  3. ncbi request reprint Earlier blood pressure-lowering and greater attenuation of hematoma growth in acute intracerebral hemorrhage: INTERACT pilot phase
    Hisatomi Arima
    The George Institute for Global Health, Royal Prince Alfred Hospital and University of Sydney, Sydney, Australia
    Stroke 43:2236-8. 2012
    ..The present analysis aimed to determine the treatment effects on hematoma growth by time from intracerebral hemorrhage onset to randomization...
  4. doi request reprint Effects of perindopril-based lowering of blood pressure on intracerebral hemorrhage related to amyloid angiopathy: the PROGRESS trial
    Hisatomi Arima
    The George Institute for International Health, University of Sydney and The Royal Prince Alfred Hospital, Sydney, Australia
    Stroke 41:394-6. 2010
    ..The objective is to determine whether lowering of blood pressure (BP) provides protection for this high-risk patient group...
  5. ncbi request reprint Lower target blood pressures are safe and effective for the prevention of recurrent stroke: the PROGRESS trial
    Hisatomi Arima
    The George Institute for International Health, University of Sydney, Sydney, NSW, Australia
    J Hypertens 24:1201-8. 2006
    ..To explore the likely optimum blood pressure (BP) level for patients with a history of cerebrovascular disease...
  6. pmc Current management of intracerebral haemorrhage in China: a national, multi-centre, hospital register study
    Jade W Wei
    The George Institute for Global Health, Royal Prince Alfred Hospital and University of Sydney, Sydney, Australia
    BMC Neurol 11:16. 2011
    ..We aimed to examine current practice of the management and secondary prevention of intracerebral haemorrhage (ICH) in China where the disease is more common than in Western populations...
  7. doi request reprint Effects of early intensive blood pressure-lowering treatment on the growth of hematoma and perihematomal edema in acute intracerebral hemorrhage: the Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT)
    Craig S Anderson
    The George Institute for International Health, Royal Prince Alfred Hospital and the University of Sydney, Sydney, Australia
    Stroke 41:307-12. 2010
    ..The present analyses aimed to determine the effects of treatment on hematoma and perihematomal edema over 72 hours...
  8. doi request reprint Statistical analysis plan for the second INTEnsive blood pressure Reduction in Acute Cerebral hemorrhage Trial (INTERACT2): a large-scale investigation to solve longstanding controversy over the most appropriate management of elevated blood pressure in th
    Craig Anderson
    The George Institute for Global Health, University of Sydney, Royal Prince Alfred Hospital and University of Sydney, Missenden Road, Camperdown, ACT 2050, Australia
    Int J Stroke 8:327-8. 2013
    ..The Statistical analysis plan (SAP) for the second INTEnsive blood pressure Reduction in Acute Cerebral hemorrhage Trial (INTERACT2)...
  9. doi request reprint Rapid blood-pressure lowering in patients with acute intracerebral hemorrhage
    Craig S Anderson
    George Institute For Global Health, University of Sydney, Sydney, NSW, Australia
    N Engl J Med 368:2355-65. 2013
    ..Whether rapid lowering of elevated blood pressure would improve the outcome in patients with intracerebral hemorrhage is not known...
  10. doi request reprint Effects of blood pressure lowering on intracranial and extracranial bleeding in patients on antithrombotic therapy: the PROGRESS trial
    Hisatomi Arima
    George Institute For Global Health, PO Box M201, Missenden Road, NSW 2050 Australia
    Stroke 43:1675-7. 2012
    ..The objective was to determine whether blood pressure lowering reduces risks of bleeding in patients on antithrombotic therapy...
  11. doi request reprint Prognostic Significance of Hyponatremia in Acute Intracerebral Hemorrhage: Pooled Analysis of the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial Studies
    Cheryl Carcel
    1Neurological and Mental Health Division, The George Institute for Global Health, University of Sydney and Royal Prince Alfred Hospital, Sydney, NSW, Australia 2Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China 3Department of Neurology, Hebei Yutian Hospital, Tangshan, China 4Department of Neurology, Xuzhou Central Hospital, Xuzhou, China 5Department of Neurology, West China Hospital, Sichuan University, Chengdu, China 6Servicio de Neurología, Departamento de Medicina, Clinica Alemana, Universidad del Desarrollo, Santiago, Chile 7Department of Cardiovascular Sciences and NIHR Biomedical Research Unit for Cardiovascular Diseases, University of Leicester, Leicester, United Kingdom
    Crit Care Med 44:1388-94. 2016
    ..To determine the association of hyponatremia at presentation with clinical and imaging outcomes in patients with acute intracerebral hemorrhage...
  12. doi request reprint Degree and Timing of Intensive Blood Pressure Lowering on Hematoma Growth in Intracerebral Hemorrhage: Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial-2 Results
    Cheryl Carcel
    From the Neurological and Mental Health Division, The George Institute for Global Health, Sydney, New South Wales, Australia C C, X W, S S, E C S, C D, H A, J C, C S A Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia C C, X W, C D, J C, C S A Department of Neurology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia C C, C D, J C, C S A Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan S S Centre de Recherche du Centre Hospitalier de l Université de Montréal CRCHUM, Departement de Neurosciences, Universite de Montreal, Montreal, Quebec, Canada C S Department of Neurology, Oslo University Hospital, Oslo, Leeds
    Stroke 47:1651-3. 2016
    ..Degree and timing of blood pressure (BP) lowering treatment in relation to hematoma growth were investigated in the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial-2 (INTERACT2)...
  13. doi request reprint Determinants and Prognostic Significance of Hematoma Sedimentation Levels in Acute Intracerebral Hemorrhage
    Shoichiro Sato
    The George Institute for Global Health, The University of Sydney and Royal Prince Alfred Hospital, Sydney, N S W, Australia
    Cerebrovasc Dis 41:80-6. 2016
    ....
  14. doi request reprint Prognostic Significance of Hyperglycemia in Acute Intracerebral Hemorrhage: The INTERACT2 Study
    Anubhav Saxena
    From the The George Institute for Global Health, Royal Prince Alfred Hospital, Sydney, NSW, Australia A S, C S A, X W, S S, H A, E C, P M V, C D, B N, J C, E H Central Clinical School, University of Sydney, Sydney, Australia A S, C S A, X W, E C, P M V, C D, B N, J C, E H Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Japan H A Clínica Alemana de Santiago, Universidad del Desarrollo, Chile P M V, P M L Department of Cardiovascular Sciences and NIHR Biomedical Research Unit in Cardiovascular Disease, University of Leicester, Leicester, UK T R CRCHUM, Departement de Neurosciences, United Kingdom
    Stroke 47:682-8. 2016
    ..We aimed to determine associations of baseline blood glucose and diabetes mellitus with clinical outcomes in participants of the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT2)...
  15. pmc Optimal achieved blood pressure in acute intracerebral hemorrhage: INTERACT2
    Hisatomi Arima
    From The George Institute for Global Health H A, E H, C D, Y H, X W, M W, J C, C S A, University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia Department of Cardiovascular Sciences and NIHR Biomedical Research Unit in Cardiovascular Disease T R, University of Leicester, UK Department of Neurology C S, APHP, Hôpital Lariboisière and DHU NeuroVasc Paris, Sorbonne, Universite Paris Diderot, Sorbonne Paris Cité, Paris, France Department of Neurology M P, John Hunter Hospital, University of Newcastle, Australia Servicio de Neurología P M L, Departamento de Medicina, Clinica Alemana, Universidad del Desarrollo, Santiago Departamento de Ciencias Neurológicas P M L, Universidad de Chile, Santiago Department of Neurology Y H, Peking University First Hospital, Beijing and The Shanghai Institute of Hypertension J W, Rui Jin Hospital, Shanghai Jiaotong University, Shanghai, China
    Neurology 84:464-71. 2015
    ..To investigate the effects of intensive blood pressure (BP) lowering according to baseline BP levels and optimal achieved BP levels in patients with acute intracerebral hemorrhage (ICH)...
  16. doi request reprint Rapid Blood Pressure Lowering According to Recovery at Different Time Intervals after Acute Intracerebral Hemorrhage: Pooled Analysis of the INTERACT Studies
    Xia Wang
    The George Institute for Global Health, University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia
    Cerebrovasc Dis 39:242-8. 2015
    ..We aimed at more reliably quantifying the benefits of this treatment according to different time periods in the recovery of participants in the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT) studies...
  17. doi request reprint Significance of Hematoma Shape and Density in Intracerebral Hemorrhage: The Intensive Blood Pressure Reduction in Acute Intracerebral Hemorrhage Trial Study
    Candice Delcourt
    From the Neurology Department, Royal Prince Alfred Hospital, Sydney, Australia C D, L D, C S A Neurological and Mental Health Division, The George Institute for Global Health, Sydney, New South Wales, Australia H A, S S, X W, J C, E H, R I L Department of Neurology, West China Hospital, Sichuan University, Chengdu, China S Z, M L Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom R A S S Division of Clinical Neurosciences, Centre de recherche du Centre hospitalier de l Université de Montréal CRCHUM, Departement de Neurosciences, Universite de Montreal, Montreal, QC, Canada C S Department of Cardiovascular Sciences and NIHR Biomedical Research Unit in Cardiovascular Disease, University of Leicester, Leicester, United Kingdom T R Unidad de Neurología vascular, Servicio de Neurologia, Departamento de Medicina, Clinica Alemana, Santiago, Chile P M L Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago, Chile P M L and Department of Medicine, Virginia Commonwealth University
    Stroke 47:1227-32. 2016
    ..In patients with acute intracerebral hemorrhage (ICH), the shape and density of the hematoma are associated with its subsequent growth, but the impact of these parameters on clinical outcome is uncertain...
  18. doi request reprint Associations with health-related quality of life after intracerebral haemorrhage: pooled analysis of INTERACT studies
    Candice Delcourt
    The George Institute for Global Health, The University of Sydney, Sydney, New South Wales, Australia
    J Neurol Neurosurg Psychiatry . 2016
    ..We aimed to determine baseline factors associated with HRQoL among participants of the pilot and main phases of the Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trials (INTERACT 1 and 2)...
  19. doi request reprint Mannitol and Outcome in Intracerebral Hemorrhage: Propensity Score and Multivariable Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial 2 Results
    Xia Wang
    From The George Institute for Global Health, School of Public Health, The University of Sydney, Sydney, Australia X W, H A, M W, P M V, E H, C D, R I L, J C, C S A Neurology Department, Royal Prince Alfred Hospital, Sydney, Australia C D, C S A Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China J Y Department of Neurology, West China Hospital, Sichuan University, Chengdu, China S Z Department of Neurology, Hebei Yutian Hospital, Tangshan, China G W Servicio de Neurología, Departamento de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago, Chile P M V, P M L Departamento de Ciencias Neurológicas, Universidad de Chile, Santiago, Chile P M L Department of Neurology, APHP Hôpital Lariboisière and DHU NeuroVasc Paris Sorbonne, Houston 77030
    Stroke 46:2762-7. 2015
    ..We aimed to determine the impact of mannitol on outcome among participants of the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT2)...
  20. doi request reprint Poor utility of grading scales in acute intracerebral hemorrhage: results from the INTERACT2 trial
    Emma Heeley
    The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia
    Int J Stroke 10:1101-7. 2015
    ..Several simple clinical grading scores have been developed for intracerebral hemorrhage, primarily to predict 30-day mortality...
  21. doi request reprint White blood cell count and clinical outcomes after intracerebral hemorrhage: The INTERACT2 trial
    Sungwook Yu
    Department of Neurology, Korea University College of Medicine, Seoul, Republic of Korea The George Institute for Global Health, Royal Prince Alfred Hospital, University of Sydney, Sydney, Australia
    J Neurol Sci 361:112-6. 2016
    ..The aim of this study was to determine associations of peripheral white blood cell (WBC) count on clinical outcome among participants of the INTERACT2 study...
  22. doi request reprint Degree of blood pressure reduction and recurrent stroke: the PROGRESS trial
    Hisatomi Arima
    The George Institute for Global Health, University of Sydney, Sydney, New South Wales, Australia
    J Neurol Neurosurg Psychiatry 85:1284-5. 2014
    ..We aimed to determine whether large treatment-related BP reductions are associated with increased risks of recurrent stroke...
  23. doi request reprint Estimated GFR and the Effect of Intensive Blood Pressure Lowering After Acute Intracerebral Hemorrhage
    Danni Zheng
    The George Institute for Global Health, Sydney, Australia Sydney Medical School, University of Sydney, Sydney, Australia
    Am J Kidney Dis 68:94-102. 2016
    ....
  24. doi request reprint Admission Heart Rate Predicts Poor Outcomes in Acute Intracerebral Hemorrhage: The Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial Studies
    Miaoyan Qiu
    From the Neurological and Mental Health Division, The George Institute for Global Health, The University of Sydney, Sydney, New South Wales, Australia M Q, S S, D Z, X W, C C, Y H, E C S, C D, J C, C S A The Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University, Shanghai, China M Q, J W Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan S S Neurology Department, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia C C, C D, J C, C S A Department of Neurology, Oslo University Hospital, Oslo, Norway E C S and Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University, Fukuoka, Japan H A
    Stroke 47:1479-85. 2016
    ..We aimed to determine the effect of admission heart rate on clinical and imaging outcomes in patients with intracerebral hemorrhage...
  25. pmc Low Ambient Temperature and Intracerebral Hemorrhage: The INTERACT2 Study
    Danni Zheng
    Division of Neurology and Mental health, The George Institute for Global Health, Sydney, New South Wales, Australia
    PLoS ONE 11:e0149040. 2016
    ..We aimed to quantify the association of ambient temperature with the risk of ICH in the Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT2) participants on an hourly timescale...
  26. doi request reprint Impact of visit-to-visit glycemic variability on the risks of macrovascular and microvascular events and all-cause mortality in type 2 diabetes: the ADVANCE trial
    Yoichiro Hirakawa
    The George Institute for Global Health, University of Sydney, Sydney, Australia
    Diabetes Care 37:2359-65. 2014
    ..Therefore, we assessed the effects of visit-to-visit variability (VVV) in HbA1c and fasting glucose on major outcomes in the ADVANCE (Action in Diabetes and Vascular Disease: Preterax and Diamicron MR Controlled Evaluation) trial...
  27. pmc Effects of the endpoint adjudication process on the results of a randomised controlled trial: the ADVANCE trial
    Jun Hata
    The George Institute for Global Health, University of Sydney, Sydney, New South Wales, Australia
    PLoS ONE 8:e55807. 2013
    ..The aim of the present analysis is to assess the effects of the endpoint adjudication process on the main findings of the ADVANCE trial (Trial registration: ClinicalTrials.gov NCT00145925)...
  28. doi request reprint Comparison of recovery patterns and prognostic indicators for ischemic and hemorrhagic stroke in China: the ChinaQUEST (QUality Evaluation of Stroke Care and Treatment) Registry study
    Jade W Wei
    BPharm, The George Institute for International Health, PO Box M201, Missenden Road, Camperdown NSW 2050, Australia
    Stroke 41:1877-83. 2010
    ..Limited data exist on the comparative recovery patterns and outcomes of patients with ischemic stroke and intracerebral hemorrhage in China...
  29. doi request reprint The effects of blood pressure reduction and of different blood pressure-lowering regimens on major cardiovascular events according to baseline blood pressure: meta-analysis of randomized trials
    Sebastien Czernichow
    The George Institute, Sydney, Australia
    J Hypertens 29:4-16. 2011
    ..The objective was to compare the risk reductions achieved by different blood pressure-lowering regimens among individuals with different baseline blood pressures...
  30. ncbi request reprint Management of hypertension: evidence from the Blood Pressure Lowering Treatment Trialists' Collaboration and from major clinical trials
    John Chalmers
    The George Institute for International Health, University of Sydney and The Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
    Pol Arch Med Wewn 119:373-80. 2009
    ..Combinations to avoid in patients with uncomplicated hypertension include ACEI and beta-blockers and ACEI and ARBs, since their beneficial effects are not additive...
  31. doi request reprint Prognostic significance of delayed intraventricular haemorrhage in the INTERACT studies
    Tom J Moullaali
    The George Institute for Global Health, Sydney, Australia
    J Neurol Neurosurg Psychiatry . 2016
    ..We determined the prognostic significance of dIVH in the Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trials (INTERACT 1 and 2)...
  32. doi request reprint Off-Hour Admission and Outcomes in Patients with Acute Intracerebral Hemorrhage in the INTERACT2 Trial
    Shoichiro Sato
    The George Institute for Global Health, University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia
    Cerebrovasc Dis 40:114-20. 2015
    ....
  33. doi request reprint Significance of Cerebral Small-Vessel Disease in Acute Intracerebral Hemorrhage
    Shoichiro Sato
    From the Neurological and Mental Health Division, George Institute For Global Health, Sydney, New South Wales, Australia S S, C D, E H, H A, R I L, J C, C S A Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan S S Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia C D, E H, H A, L D, R I L, J C, C S A Neurology Department, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia C D, L D, J C, C S A Center for Epidemiologic Research in Asia, Shiga University of Medical Sciences, Shiga, Japan H A Department of Neurology, West China Hospital, Sichuan University, Boston
    Stroke 47:701-7. 2016
    ....
  34. doi request reprint Clinical prediction algorithm (BRAIN) to determine risk of hematoma growth in acute intracerebral hemorrhage
    Xia Wang
    From the The George Institute for Global Health, University of Sydney, Sydney, Australia X W, H A, M W, E H, C D, C S A Royal Prince Alfred Hospital, Sydney, Australia X W, H A, M W, E H, C D, C S A Division of Clinical Neurosciences, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK R A S S Department of Neurology, APHP HôpitalLariboisière and DHU NeuroVasc Paris Sorbonne, Univ Paris Diderot Sorbonne Paris Cité, Paris, France C S Servicio de Neurología, Departamento de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago, Chile P M L Universidad de Chile, Santiago, Chile P M L Department of Cardiovascular Sciences and NIHR Biomedical Research Unit in Cardiovascular Disease, University of Leicester, Leicester, UK T R Department of Neurology, Peking University First Hospital, Beijing, China Y H and The Shanghai Institute of Hypertension, Rui Jin Hospital, Shanghai Jiaotong University
    Stroke 46:376-81. 2015
    ..We developed and validated a simple algorithm to predict the risk of hematoma growth in acute spontaneous intracerebral hemorrhage (ICH) to better inform clinicians and researchers in their efforts to improve outcomes for patients...
  35. doi request reprint Ambient temperature and volume of perihematomal edema in acute intracerebral haemorrhage: the INTERACT1 study
    Danni Zheng
    The George Institute for Global Health, Royal Prince Alfred Hospital, Sydney, Australia Sydney Medical School, University of Sydney, Sydney, Australia
    Int J Stroke 10:25-7. 2015
    ....
  36. doi request reprint Comparative effects of antihypertensive drugs on stroke outcome in China
    Emma L Heeley
    The George Institute for Global Health, Sydney Medical School, University of Sydney, Sydney, Australia
    Int J Stroke 9:113-8. 2014
    ..Antihypertensive drugs are useful in the prevention of stroke; however, much debate surrounds which class of agent provides the most benefit post-stroke...
  37. ncbi request reprint Secondary prevention of stroke by blood pressure-lowering treatment
    Hisatomi Arima
    The George Institute for International Health, University of Sydney, PO Box M201, Missenden Road, NSW 2050, Australia
    Curr Hypertens Rep 8:317-23. 2006
    ....
  38. ncbi request reprint Chronic kidney disease, cardiovascular events, and the effects of perindopril-based blood pressure lowering: data from the PROGRESS study
    Vlado Perkovic
    George Institute for International Health, PO Box M201, Sydney, Australia, 2050
    J Am Soc Nephrol 18:2766-72. 2007
    ..In conclusion, kidney function should be considered when determining the need for blood pressure lowering therapy in patients with cerebrovascular disease...
  39. ncbi request reprint Circadian variation in clinical features and outcome of intracerebral hemorrhage: The INTERACT studies
    Danni Zheng
    a Neurological and Mental Health Division, The George Institute for Global Health, Sydney, Australia
    Chronobiol Int 33:1182-1187. 2016
    ..There was no circadian influence on ICH clinical outcome...
  40. doi request reprint Statistical analysis plan for evaluating low- vs. standard-dose alteplase in the ENhanced Control of Hypertension and Thrombolysis strokE stuDy (ENCHANTED)
    Craig S Anderson
    The George Institute for Global Health, Royal Prince Alfred Hospital and University of Sydney, Sydney, NSW, Australia
    Int J Stroke 10:1313-5. 2015
    ....
  41. doi request reprint Prediction of kidney-related outcomes in patients with type 2 diabetes
    Meg J Jardine
    George Institute For Global Health, Sydney, Australia
    Am J Kidney Dis 60:770-8. 2012
    ..Tools are needed to predict which individuals with diabetes will develop kidney disease and its complications...
  42. doi request reprint Effects of prehypertension and hypertension subtype on cardiovascular disease in the Asia-Pacific Region
    Hisatomi Arima
    George Institute For Global Health, University of Sydney, Sydney, New South Wales, Australia
    Hypertension 59:1118-23. 2012
    ..In the Asia-Pacific region, prehypertension and all hypertension subtypes, including IDH, thus clearly predicted increased risks of CVD...
  43. doi request reprint PROGRESS: Prevention of Recurrent Stroke
    Hisatomi Arima
    George Institute For Global Health, University of Sydney and The Royal Prince Alfred Hospital, Sydney, Australia
    J Clin Hypertens (Greenwich) 13:693-702. 2011
    ..On the basis of recommendations from current international guidelines, BP should be lowered to <140/90 mm Hg in all patients with cerebrovascular disease and to <130/80 mm Hg if therapy is well tolerated...
  44. doi request reprint Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial
    Craig S Anderson
    The George Institute for International Health, The University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia
    Lancet Neurol 7:391-9. 2008
    ..Our aim was to assess the safety and efficiency of this treatment, as a run-in phase to a larger trial...
  45. doi request reprint Higher mortality in patients with right hemispheric intracerebral haemorrhage: INTERACT1 and 2
    Shoichiro Sato
    The George Institute for Global Health, The University of Sydney and Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
    J Neurol Neurosurg Psychiatry 86:1319-23. 2015
    ..Controversy exists over the prognostic significance of the affected hemisphere in stroke. We aimed to determine the relationship between laterality of acute intracerebral haemorrhage (ICH) and poor clinical outcomes...
  46. doi request reprint Significance of intraventricular hemorrhage in acute intracerebral hemorrhage: intensive blood pressure reduction in acute cerebral hemorrhage trial results
    Edward Chan
    From The George Institute for Global Health, Neurological and Mental Health Division, Royal Prince Alfred Hospital, Sydney, Australia E C, C S A, X W, H A, A s, T J M, E H, C D, J C Central Clinical School, University of Sydney, Sydney, Australia E C, C S A, X W, H A, A s, E H, C D, J C Department of Neurology, Hebei Yutian Hospital, Tangshan, China G W, J W Department of Neurology, Xuzhou Central Hospital, Jiangsu, China G C Servicio de Neurología, Departamento de Medicina, Clinica Alemana, Universidad del Desarrollo, Santiago, Chile P M L Department of Neurological Sciences, USA
    Stroke 46:653-8. 2015
    ..We aimed to elucidate risk associations of IVH and outcome in the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT2) data set...
  47. doi request reprint A comparative analysis of risk factors and stroke risk for Asian and non-Asian men: the Asia Pacific cohort studies collaboration
    Karice K Hyun
    The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia
    Int J Stroke 8:606-11. 2013
    ..The risk of stroke is high in men among both Asian and non-Asian populations, despite differences in risk factor profiles; whether risk factors act similarly in these populations is unknown...
  48. doi request reprint Design of the CHina Epidemiology Research in Subarachnoid Haemorrhage (CHERISH) study
    Ivy Shiue
    The George Institute for Global Health, Royal Prince Alfred Hospital and the University of Sydney, Sydney, NSW 2050, Australia
    Int J Stroke 5:493-8. 2010
    ..We report the methods and the initial experience of a new study to address this deficiency...
  49. doi request reprint Secondary prevention of ischemic stroke in urban China
    Jade W Wei
    The George Institute for International Health, PO Box M201, Missenden Rd, Camperdown NSW 2050, Australia
    Stroke 41:967-74. 2010
    ..We aimed to describe the uptake of proven secondary prevention strategies for ischemic stroke in urban China...
  50. doi request reprint Dietary intake of key nutrients and subarachnoid hemorrhage: a population-based case-control study in Australasia
    Ivy Shiue
    The George Institute for Global Health, Royal Prince Alfred Hospital and the University of Sydney, Sydney, N S W, Australia
    Cerebrovasc Dis 31:464-70. 2011
    ..A healthy, balanced diet can prevent stroke, but little is known about dietary risk factors for subarachnoid hemorrhage (SAH). We aimed to determine the relationship between common dietary habits and risk of SAH...
  51. doi request reprint Ambient temperature and severity of intracerebral haemorrhage: the INTERACT1 study
    Danni Zheng
    The George Institute for Global Health, Royal Prince Alfred Hospital and Sydney Medical School, University of Sydney, Sydney, N S W, Australia
    Neuroepidemiology 42:169-73. 2014
    ..We aimed to determine associations of ambient temperature with clinical severity and haematoma size in acute ICH among Chinese participants in the Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT1)...
  52. doi request reprint Global survey of current practice in management of hypertension as reported by societies affiliated with the International Society of Hypertension
    John Chalmers
    The George Institute for Global Health, University of Sydney and The Royal Prince Alfred Hospital, Sydney, Australia
    J Hypertens 31:1043-8. 2013
    ..The International Society of Hypertension (ISH) surveyed trends in the management of hypertension worldwide, as reported by its affiliated societies...
  53. doi request reprint Mortality patterns in hypertension
    Hisatomi Arima
    The George Institute for Global Health, University of Sydney and Royal Prince Alfred Hospital, Sydney, NSW 2050 Australia
    J Hypertens 29:S3-7. 2011
    ..Reductions in the burden of BP-related death require the parallel application of the population strategy at community level and the clinical strategy focusing on new and improved treatments for people with hypertension...
  54. pmc Ambient Temperature and Stroke Occurrence: A Systematic Review and Meta-Analysis
    Xia Wang
    The George Institute for Global Health and Royal Prince Alfred Hospital, The University of Sydney, P O Box M201, Missenden Road, Sydney, NSW 2050, Australia
    Int J Environ Res Public Health 13:. 2016
    ..To conclude, this review shows that lower mean ambient temperature is significantly associated with the risk of ICH, but not with IS and SAH. Larger temperature changes were associated with higher stroke rates in the elderly. ..
  55. pmc Head Position in Stroke Trial (HeadPoST)--sitting-up vs lying-flat positioning of patients with acute stroke: study protocol for a cluster randomised controlled trial
    Paula Muñoz-Venturelli
    The George Institute for Global Health, University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia
    Trials 16:256. 2015
    ....
  56. doi request reprint Renin-angiotensin system blockade and cognitive function in patients at high risk of cardiovascular disease: analysis of data from the ONTARGET and TRANSCEND studies
    Craig Anderson
    The George Institute for Global Health, University of Sydney and Royal Prince Alfred Hospital, Sydney, NSW, Australia
    Lancet Neurol 10:43-53. 2011
    ..We investigated the effects of renin-angiotensin system blockade on cognitive function in patients aged 55 years and older with established atherosclerotic cardiovascular disease or diabetes with end-organ damage in two clinical trials...
  57. ncbi request reprint Importance of blood pressure lowering in type 2 diabetes: focus on ADVANCE
    John Chalmers
    The George Institute for International Health, The University of Sydney and Royal Prince Alfred Hospital, Sydney, NSW, Australia
    J Cardiovasc Pharmacol 55:340-7. 2010
    ....
  58. ncbi request reprint Perindopril-based blood pressure-lowering reduces major vascular events in patients with atrial fibrillation and prior stroke or transient ischemic attack
    Hisatomi Arima
    George Institute for International Health, University of Sydney, Australia
    Stroke 36:2164-9. 2005
    ..The primary objective here is to determine whether routine blood pressure-lowering provides additional protection for this high-risk patient group...
  59. doi request reprint No relationship of lipid-lowering agents to hematoma growth: pooled analysis of the intensive blood pressure reduction in acute cerebral hemorrhage trials studies
    Miriam Priglinger
    From the Department of Neurology, Stroke Network, Royal North Shore Hospital, Sydney, Australia M P, M K Department of Neurology, George Institute For Global Health, Royal Prince Alfred Hospital, Sydney, Australia H A, C A and Sydney Medical School, University of Sydney, Sydney, Australia M K, H A, C A
    Stroke 46:857-9. 2015
    ..We determined associations of premorbid lipid-lowering therapy and outcomes among participants of the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trials (INTERACT)...
  60. doi request reprint Life events and risk of subarachnoid hemorrhage: the australasian cooperative research on subarachnoid hemorrhage study (ACROSS)
    Ivy Shiue
    The George Institute for International Health, Royal Prince Alfred Hospital and the University of Sydney, PO Box M201, Missenden Road, NSW 2050, Australia
    Stroke 41:1304-6. 2010
    ..Because little evidence exists and the topic often raises concerns, we aimed to determine the relationship between life events and subarachnoid hemorrhage (SAH) in a population-based case-control setting...