M L Selley
- Effect of anethole dithiolthione on human platelet aggregationM L Selley
Australian National University, John Curtin School of Medical Research, Division of Clinical Sciences, Garran, A C T
Arzneimittelforschung 42:318-21. 1992..ADT inhibited the release of 3H-AA from platelet phospholipids in response to ADP and collagen. It is suggested that ADT inhibits platelet aggregation by inhibiting thromboxane synthesis and preventing AA release...
- (E)-4-hydroxy-2-nonenal may be involved in the pathogenesis of Parkinson's diseaseM L Selley
Division of Clinical Sciences, The John Curtin School of Medical Research, The Australian National University, The Canberra Hospital, Garran, ACT
Free Radic Biol Med 25:169-74. 1998..32+/-0.12 microM/g wet wt. (n=4) while the control value was 0.04+/-0.02 microM/g wet wt. (n=8). These data suggest that HNE may be a causative neurotoxin in Parkinson's disease and that HNE may also be involved in MPTP toxicity...
- The role of (E)-4-hydroxy-2-nonenal in platelet activation by low density lipoprotein and ironM L Selley
Division of Clinical Sciences, John Curtin School of Medical Research, The Australian National University, Royal Canberra Hospital, Garran, ACT
Atherosclerosis 140:105-12. 1998..The results suggest iron could increase platelet reactivity at sites of vascular injury by increasing HNE formation and promote the development of atherosclerotic lesions...