Mark T Mackay
Affiliation: Royal Children's Hospital
- Stroke in childrenMark T Mackay
Children s Neuroscience Centre, Royal Children s Hospital, Melbourne, Victoria
Aust Fam Physician 36:896-902. 2007..Ten percent of children suffering stroke will die as a result, and at least 50% of survivors are left with significant neurological disabilities, learning difficulties or seizures...
- The ketogenic diet in refractory childhood epilepsyMark T Mackay
Children s Epilepsy Program, Department of Neurology, Royal Children s Hospital, University of Melbourne, Melbourne, Victoria, Australia
J Paediatr Child Health 41:353-7. 2005..To report the efficacy and tolerability of the ketogenic diet (KD) in refractory paediatric epilepsy...
- Fits, faints and funny turns in childrenMark Mackay
Royal Children s Hospital, Melbourne, Victoria
Aust Fam Physician 34:1003-8. 2005..There are many other paroxysmal disorders that can mimic seizures and it is important to exclude these conditions before diagnosing epilepsy and making the decision to commence anticonvulsant treatment...
- Arterial ischemic stroke risk factors: the International Pediatric Stroke StudyMark T Mackay
Children s Neuroscience Centre, Royal Children s Hospital, Murdoch Children s Research Institute and Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia
Ann Neurol 69:130-40. 2011..To describe presumptive risk factors (RFs) for childhood arterial ischemic stroke (AIS) and explore their relationship with presentation, age, geography, and infarct characteristics...
- Childhood posterior circulation arterial ischemic strokeMark T Mackay
Children s Neuroscience Centre, Royal Children s Hospital Melbourne, Melbourne, Australia
Stroke 41:2201-9. 2010..We describe clinical and radiological features of childhood PCAIS to determine whether there are differences in infarct topography, vascular abnormalities, risk factors, and stroke subtypes when compared to adults...
- High resolution chromosomal microarray in undiagnosed neurological disordersKatherine B Howell
Department of Neurology, Royal Children s Hospital, Melbourne, Victoria, Australia
J Paediatr Child Health 49:716-24. 2013..Although recent studies have identified pathogenic CNVs in intellectual disability, autism and epilepsy, the utility of CMA testing in a broader cohort of children with neurologic disorders has not been reported...
- Symptomatic generalized epilepsy after HHV6 posttransplant acute limbic encephalitis in childrenKatherine B Howell
Department of Neurology, The Royal Children s Hospital, Melbourne, Australia
Epilepsia 53:e122-6. 2012....
- Does epilepsy occur more frequently in children with Type 1 diabetes?Michele A O'Connell
Department of Endocrinology and Diabetes, Royal Children s Hospital, Victoria, Australia
J Paediatr Child Health 44:586-9. 2008..We aimed to determine the prevalence and type of epilepsy in a large paediatric diabetes clinic...
- Efficacy of the ketogenic diet: which epilepsies respond?Sasipa Thammongkol
Children s Neuroscience Centre, Royal Children s Hospital, Parkville, Victoria, Australia
Epilepsia 53:e55-9. 2012..The response is predicted by type of epilepsy syndrome. Accurate characterization of the electroclinical syndrome is an important factor in decisions about timing of initiation of the ketogenic diet...
- Family-centred outcome measurement following paediatric strokeJane Galvin
Victorian Paediatric Rehabilitation Service, The Royal Children s Hospital, Melbourne, Victoria, Australia
Aust Occup Ther J 57:152-8. 2010..This project aimed to describe the functional concerns identified by children and their parents following paediatric stroke...
- Factors associated with six-month outcome of pediatric strokeAnne L Gordon
Clinical Sciences Theme, Murdoch Childrens Research Institute, Melbourne, Vic, Australia
Int J Stroke 10:1068-73. 2015..Pediatric stroke outcome studies are often cross sectional in design. Prospective information regarding the clinical course following diagnosis is lacking, but may inform clinical management beyond the acute period...
- Stroke and nonstroke brain attacks in childrenMark T Mackay
From the Department of Neurology M T M and Emergency Department Z K C, M L, F E B, Royal Children s Hospital Melbourne, Parkville Murdoch Childrens Research Institute M T M, F E B, Parkville Florey Institute of Neurosciences and Mental Health M T M, L C, G A D, Parkville University of Melbourne M T M, Z K C, M L, L C, P M, G A D, F E B, Parkville, Australia and Hospital Nacional de Ninos A Y C, San Jose, Costa Rica
Neurology 82:1434-40. 2014..To determine symptoms, signs, and etiology of brain attacks in children presenting to the emergency department (ED) as a first step for developing a pediatric brain attack pathway...
- Hypertension at time of diagnosis and long-term outcome after childhood ischemic strokeLauren N Brush
School of Medicine, University of Melbourne, Australia
Neurology 80:1225-30. 2013..To determine the prevalence of hypertension (HPT) in the acute phase after ischemic stroke (IS) and explore its relationship to outcome...
- Epileptic spasms: experience with a high-dose oral corticosteroid protocolTyson L Ware
Department of Neurology, Parkville University of Melbourne, Melbourne, Victoria, Australia
J Paediatr Child Health 48:985-9. 2012..To audit clinical practice and assess early outcomes for infants with epileptic spasms after an agreed initial treatment protocol was adopted...
- Long-term follow-up of febrile infection-related epilepsy syndromeKatherine B Howell
Department of Neurology, The Royal Children s Hospital, Melbourne, Victoria, Australia
Epilepsia 53:101-10. 2012..Herein we describe the features of the chronic epilepsy and critically review evidence for the etiology of this syndrome...
- Can the FAST and ROSIER adult stroke recognition tools be applied to confirmed childhood arterial ischemic stroke?Adriana Yock-Corrales
Emergency Department, Royal Children s Hospital, Melbourne, Australia
BMC Pediatr 11:93. 2011..Two adult stroke recognition tools; ROSIER (Recognition of Stroke in the Emergency Room) and FAST (Face Arm Speech Test) scales were applied retrospectively to all patients to determine test sensitivity...
- SCN2A encephalopathy: A major cause of epilepsy of infancy with migrating focal seizuresKatherine B Howell
From the Departments of Neurology K B H, M T M, V R C, J L F, A S H, I E S and Radiology S M, The Royal Children s Hospital, Melbourne Department of Paediatrics K B H, M T M, S M, A S H, I E S, The University of Melbourne Murdoch Childrens Research Institute K B H, M T M, J L F, A S H, Melbourne Epilepsy Research Centre J M M, I E S, Department of Medicine, University of Melbourne, Austin Health, Melbourne, Australia Division of Genetic Medicine G L C, H C M, Department of Paediatrics, University of Washington, Seattle Epilepsy Genetics Program D T, H E O, A P, Department of Neurology, Harvard Medical School, Boston Children s Hospital, MA TY Nelson Department of Neurology and Neurosurgery R W, The Children s Hospital at Westmead, Sydney Department of Neurology D C, Women s and Children s Hospital
Neurology 85:958-66. 2015..De novo SCN2A mutations have recently been associated with severe infantile-onset epilepsies. Herein, we define the phenotypic spectrum of SCN2A encephalopathy...
- Decompressive craniectomy in childhood posterior circulation stroke: a case series and review of the literatureAlicia K Montgomery
Children s Neuroscience Centre, Royal Children s Hospital, Parkville, Melbourne, Victoria, Australia
Pediatr Neurol 47:193-7. 2012..Because decompressive craniectomy can be lifesaving in children with severe posterior circulation arterial ischemic stroke, early neurosurgical referral should be considered...
- Alpers syndrome with mutations in POLG: clinical and investigative featuresMatthew F Hunter
Genetic Health, Victorian Clinical Genetics Service, Melbourne, Victoria, Australia
Pediatr Neurol 45:311-8. 2011..Three common polymerase-γ mutations, in patients of European descent, can assist with rapid diagnosis, circumventing the need for liver biopsy...
- Acute childhood arterial ischemic and hemorrhagic stroke in the emergency departmentAdriana Yock-Corrales
Emergency Department, Royal Children s Hospital Melbourne, Victoria, Australia
Ann Emerg Med 58:156-63. 2011..Yet, initial clinical assessment is a key step in the management pathway of stroke. We describe the presentation in the ED of children with confirmed acute ischemic and hemorrhagic stroke subtypes...
- Delayed recognition of initial stroke in children: need for increased awarenessJayasri Srinivasan
Department of Paediatric Neurology, Children s Neuroscience Centre, Royal Children s Hospital, Melbourne, Australia
Pediatrics 124:e227-34. 2009..The goal was to identify the delays involved in diagnosing pediatric arterial ischemic stroke (AIS), a major cause of morbidity and death in children...
- Early-onset bilateral cerebral arteriopathies: Cohort study of phenotype and disease courseAmina Al-Yassin
From the Neurosciences Unit A A Y, V G, UCL Institute of Child Health the Radiology Department D E S, Great Ormond Street Hospital, NHS Foundation Trust, London, UK and the Neurology Department M T M, Royal Children s Hospital, Melbourne, Australia
Neurology 85:1146-53. 2015..To describe characteristics of young children with arterial ischemic stroke (AIS) and bilateral cerebral arteriopathies...
- Neurologic Melioidosis: Case Report of a Rare Cause of Acute Flaccid ParalysisErik W Andersen
Children s Neurosciences Center, The Royal Children s Hospital, Melbourne, Victoria, Australia Electronic address
J Pediatr 170:319-21. 2016..Melioidosis (Burkholderia pseudomallei infection) can rarely cause this presentation. We describe a case of spinal melioidosis in a 4-year-old boy presenting with flaccid paralysis, and review the literature on this rare disease. ..
- Functional outcome following paediatric strokeJane Galvin
Victorian Paediatric Rehabilitation Service, The Royal Children s Hospital, Melbourne, Australia
Dev Neurorehabil 14:67-71. 2011..Paediatric stroke has a significant impact on functional ability; however, few studies describe outcomes using valid and reliable measures...
- Stroke presenting under 3 hours in patients younger than 18 years of ageCassandra Szoeke
Eastern Melbourne Neurosciences, Box Hill Hospital, Melbourne, Victoria, Australia
J Clin Neurosci 16:1481-2. 2009..Feasibility of treatment is further limited by a lack of dosage and safety data in the paediatric population. Improved community awareness and more rapid recognition of stroke may reduce lag time to diagnosis...
- Acute transverse myelitis and acute disseminated encephalomyelitis in childhood: spectrum or separate entities?Eppie M Yiu
Children s Neuroscience Centre, Royal Children s Hospital, Melbourne, Australia
J Child Neurol 24:287-96. 2009..These clinical and radiological differences suggest acute transverse myelitis and acute disseminated encephalomyelitis are separate entities...
- Accuracy of bedside electroencephalographic monitoring in comparison with simultaneous continuous conventional electroencephalography for seizure detection in term infantsDivyen K Shah
Washington University, Department of Pediatrics, One Children s Place, St Louis, MO 63110, USA
Pediatrics 121:1146-54. 2008....