Denise A Caruso
Affiliation: Royal Children's Hospital
- Costimulation molecule expression and subset distribution of blood dendritic cells in normal children and newly diagnosed pediatric leukemia and lymphoma patientsDenise A Caruso
Children s Cancer Centre, The Royal Children s Hospital, The Murdoch Childrens Research Institute, Department of Pediatrics at the University of Melbourne, Parkville, Victoria, Australia
Exp Hematol 36:1691-703. 2008..DC are potent antigen-presenting cells and are crucial for initiating specific immune responses...
- Results of a Phase I study utilizing monocyte-derived dendritic cells pulsed with tumor RNA in children with Stage 4 neuroblastomaDenise A Caruso
Department of Hematology and Oncology, The Royal Children s Hospital, Parkville, Victoria, Australia
Cancer 103:1280-91. 2005..A Phase I study of 11 pediatric patients with newly diagnosed, Stage 4 neuroblastoma was conducted using monocyte-derived dendritic cells (DC) pulsed with tumor RNA to produce antitumor vaccines (DC(RNA))...
- Results of a phase 1 study utilizing monocyte-derived dendritic cells pulsed with tumor RNA in children and young adults with brain cancerDenise A Caruso
Department of Hematology and Oncology, The Royal Children s Hospital, Parkville, Victoria, 3051, Australia
Neuro Oncol 6:236-46. 2004..Two of 7 patients who were tested showed a tumor-specific immune response to DCRNA. This study showed that DCRNA vaccines are both safe and feasible in children with tumors of the central nervous system with a single leukapheresis...
- Mobilization of dendritic cells in cancer patients treated with granulocyte colony-stimulating factor and chemotherapyFiona J Radcliff
Department of Haematology and Oncology, The Royal Children s Hospital, Parkville, Victoria, Australia
Br J Haematol 119:204-11. 2002..This strategy may be a feasible, low-risk means of acquiring cells for DC-based vaccine studies...