Kevan R Polkinghorne

Summary

Country: Australia

Publications

  1. ncbi request reprint Determinants of native arteriovenous fistula blood flow
    Kevan R Polkinghorne
    Department of Nephrology, Monash Medical Centre, Melbourne, Victoria 3168, Australia
    Nephrology (Carlton) 9:205-11. 2004
  2. doi request reprint Lateral lumbar X-ray assessment of abdominal aortic calcification in Australian haemodialysis patients
    Nigel D Toussaint
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Nephrology (Carlton) 16:389-95. 2011
  3. doi request reprint Using vertebral bone densitometry to determine aortic calcification in patients with chronic kidney disease
    Nigel D Toussaint
    Department of Nephrology, Monash Medical Centre, 246 Clayton Road, Clayton, VIC 3168, Australia
    Nephrology (Carlton) 15:575-83. 2010
  4. doi request reprint Serum 25-hydroxyvitamin D deficiency and the 5-year incidence of CKD
    Matthew J Damasiewicz
    Department of Nephrology, Monash Medical Centre, Melbourne, Australia
    Am J Kidney Dis 62:58-66. 2013
  5. pmc Determination and validation of aortic calcification measurement from lateral bone densitometry in dialysis patients
    Nigel D Toussaint
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Clin J Am Soc Nephrol 4:119-27. 2009
  6. doi request reprint Relationship between vascular calcification, arterial stiffness and bone mineral density in a cross-sectional study of prevalent Australian haemodialysis patients
    Nigel D Toussaint
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Nephrology (Carlton) 14:105-12. 2009
  7. pmc 25-Hydroxyvitamin D levels and chronic kidney disease in the AusDiab (Australian Diabetes, Obesity and Lifestyle) study
    Matthew J Damasiewicz
    Department of Nephrology, Monash Medical Centre, 246 Clayton Road, Clayton, 3168, Victoria, Australia
    BMC Nephrol 13:55. 2012
  8. doi request reprint Mycophenolate and lower graft function reduce the seroresponse of kidney transplant recipients to pandemic H1N1 vaccination
    William R Mulley
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Kidney Int 82:212-9. 2012
  9. doi request reprint Fibroblast growth factor 23 in chronic kidney disease: New insights and clinical implications
    Matthew J Damasiewicz
    Department of Nephrology, Monash Medical Centre, Monash University, Clayton, Victoria, Australia
    Nephrology (Carlton) 16:261-8. 2011
  10. doi request reprint Longitudinal body composition changes due to dialysis
    Rebecca Pellicano
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Clin J Am Soc Nephrol 6:1668-75. 2011

Collaborators

Detail Information

Publications52

  1. ncbi request reprint Determinants of native arteriovenous fistula blood flow
    Kevan R Polkinghorne
    Department of Nephrology, Monash Medical Centre, Melbourne, Victoria 3168, Australia
    Nephrology (Carlton) 9:205-11. 2004
    ..Determinants of native arteriovenous fistula (AVF) placement have been well studied. Little is known on whether these factors impact on subsequent blood flow (Qa) in the mature AVF...
  2. doi request reprint Lateral lumbar X-ray assessment of abdominal aortic calcification in Australian haemodialysis patients
    Nigel D Toussaint
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Nephrology (Carlton) 16:389-95. 2011
    ..Using simple radiological imaging we aimed to assess AAC and determine associations in prevalent Australian haemodialysis (HD) patients...
  3. doi request reprint Using vertebral bone densitometry to determine aortic calcification in patients with chronic kidney disease
    Nigel D Toussaint
    Department of Nephrology, Monash Medical Centre, 246 Clayton Road, Clayton, VIC 3168, Australia
    Nephrology (Carlton) 15:575-83. 2010
    ..VC is inversely correlated with bone mineral density (BMD). Screening for VC may be useful to determine those at greater CV risk and dual-energy X-ray absorptiometry (DXA) may have a dual role in providing VC measurement as well as BMD...
  4. doi request reprint Serum 25-hydroxyvitamin D deficiency and the 5-year incidence of CKD
    Matthew J Damasiewicz
    Department of Nephrology, Monash Medical Centre, Melbourne, Australia
    Am J Kidney Dis 62:58-66. 2013
    ..Low serum 25-hydroxyvitamin D (25[OH]D) levels have been associated with chronic kidney disease in cross-sectional studies. However, this association has not been studied prospectively in a large general population-based cohort...
  5. pmc Determination and validation of aortic calcification measurement from lateral bone densitometry in dialysis patients
    Nigel D Toussaint
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Clin J Am Soc Nephrol 4:119-27. 2009
    ..The aim of this study was to determine measurement of VC using dual-energy x-ray absorptiometry (DXA) with correlation to gold standard computed tomography (CT)...
  6. doi request reprint Relationship between vascular calcification, arterial stiffness and bone mineral density in a cross-sectional study of prevalent Australian haemodialysis patients
    Nigel D Toussaint
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Nephrology (Carlton) 14:105-12. 2009
    ..Few studies have correlated VC in the dialysis population with measurements of BMD and arterial compliance...
  7. pmc 25-Hydroxyvitamin D levels and chronic kidney disease in the AusDiab (Australian Diabetes, Obesity and Lifestyle) study
    Matthew J Damasiewicz
    Department of Nephrology, Monash Medical Centre, 246 Clayton Road, Clayton, 3168, Victoria, Australia
    BMC Nephrol 13:55. 2012
    ..We explored the relationship between 25(OH)D levels and prevalent chronic kidney disease (CKD), albuminuria and impaired GFR, in a national, population-based cohort of Australian adults (AusDiab Study)...
  8. doi request reprint Mycophenolate and lower graft function reduce the seroresponse of kidney transplant recipients to pandemic H1N1 vaccination
    William R Mulley
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Kidney Int 82:212-9. 2012
    ..Transplant recipient responses were further reduced if they were receiving mycophenolate or had significantly lower graft function...
  9. doi request reprint Fibroblast growth factor 23 in chronic kidney disease: New insights and clinical implications
    Matthew J Damasiewicz
    Department of Nephrology, Monash Medical Centre, Monash University, Clayton, Victoria, Australia
    Nephrology (Carlton) 16:261-8. 2011
    ..The discovery of FGF-23 has provided a profound new insight into bone and mineral metabolism, and it may become an important biomarker and therapeutic target in CKD...
  10. doi request reprint Longitudinal body composition changes due to dialysis
    Rebecca Pellicano
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Clin J Am Soc Nephrol 6:1668-75. 2011
    ..Nutritional status remains a powerful predictor of outcome in the dialysis population. High body mass index (BMI) seems protective, but which body compartment (fat or lean mass) confers this protection remains unclear...
  11. doi request reprint Baseline characteristics of the omega-3 fatty acids (Fish oils) and Aspirin in Vascular access OUtcomes in REnal Disease (FAVOURED) study
    Andrea K Viecelli
    Department of Nephrology, Princess Alexandra Hospital, Brisbane, Queensland, Australia
    Nephrology (Carlton) 21:217-28. 2016
    ....
  12. ncbi request reprint Vascular access practice patterns in the New Zealand hemodialysis population
    Kevan R Polkinghorne
    Department of Nephrology, Monash Medical Center, Melbourne, Victoria, Australia
    Am J Kidney Dis 43:696-704. 2004
    ..Physician practice patterns may have a strong influence on access type. We assessed differences in vascular access practice patterns across all treating centers in New Zealand...
  13. doi request reprint Impact of intradialytic exercise on arterial compliance and B-type natriuretic peptide levels in hemodialysis patients
    Nigel D Toussaint
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Hemodial Int 12:254-63. 2008
    ....
  14. ncbi request reprint HPLC-detected albuminuria predicts mortality
    Dianna J Magliano
    International Diabetes Institute, Melbourne, Victoria, Australia
    J Am Soc Nephrol 18:3171-6. 2007
    ..We conclude that albuminuria, detected by either IN or HPLC, independently predicts mortality in a community-based sample. HPLC identifies some people at increased risk of mortality that IN would not detect...
  15. doi request reprint Effect of alendronate on vascular calcification in CKD stages 3 and 4: a pilot randomized controlled trial
    Nigel D Toussaint
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Am J Kidney Dis 56:57-68. 2010
    ..Recent studies of hemodialysis patients also suggest benefits of bisphosphonates on vascular calcification; however, no study exists in nondialysis patients with CKD...
  16. doi request reprint Effect of Fish Oil Supplementation and Aspirin Use on Arteriovenous Fistula Failure in Patients Requiring Hemodialysis: A Randomized Clinical Trial
    Ashley B Irish
    Department of Nephrology, Fiona Stanley Hospital, Perth, Australia2School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    JAMA Intern Med . 2017
    ..3 Polyunsaturated fatty acids (fish oils) have pleiotropic effects on vascular biology and inflammation and aspirin impairs platelet aggregation, which may reduce access failure...
  17. ncbi request reprint Associations between vascular calcification, arterial stiffness and bone mineral density in chronic kidney disease
    Nigel D Toussaint
    Department of Nephrology, Monash Medical Centre, 246 Clayton Road, Clayton, Victoria 3168, Australia
    Nephrol Dial Transplant 23:586-93. 2008
    ..Few studies have addressed the extent of VC in the pre-dialysis CKD population, with associated measurements of BMD and arterial compliance...
  18. ncbi request reprint Native arteriovenous fistula blood flow and resistance during hemodialysis
    Kevan R Polkinghorne
    Department of Nephrology, Monash Medical Centre, Melbourne, Victoria, Australia
    Am J Kidney Dis 41:132-9. 2003
    ..Measurement of vascular access flow (Qa) has been proposed as the ideal method for surveillance of native fistulae. However, debate exists about the influence of blood pressure (mean arterial pressure [MAP]) on Qa during dialysis...
  19. ncbi request reprint Does monthly native arteriovenous fistula blood-flow surveillance detect significant stenosis--a randomized controlled trial
    Kevan R Polkinghorne
    Department of Nephrology, Monash Medical Centre, 246 Clayton Rd, Clayton, Melbourne, Victoria 3168, Australia
    Nephrol Dial Transplant 21:2498-506. 2006
    ..As these recommendations are based on observational studies, we conducted a randomized, prospective, double-blind, controlled trial to assess whether Qa surveillance results in an increased detection of AVF stenosis...
  20. doi request reprint Improving CKD-MBD management in haemodialysis patients: barrier analysis for implementing better practice
    Nigel D Toussaint
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Nephrol Dial Transplant 26:1319-26. 2011
    ..We aimed to determine potential barriers by surveying HD patients and staff about awareness and management of CKD-MBD...
  21. ncbi request reprint Vascular access and all-cause mortality: a propensity score analysis
    Kevan R Polkinghorne
    Department of Nephrology, Monash Medical Centre, Melbourne, Victoria, Australia
    J Am Soc Nephrol 15:477-86. 2004
    ..Reducing catheter use and increasing the proportion of patients commencing hemodialysis with a mature AVF remain important clinical objectives...
  22. doi request reprint Reduction in beta2-microglobulin with super-flux versus high-flux dialysis membranes: results of a 6-week, randomized, double-blind, crossover trial
    Rebecca Pellicano
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Am J Kidney Dis 52:93-101. 2008
    ....
  23. doi request reprint Effect of exercise on albuminuria in people with diabetes
    Keng Hee Koh
    Departments of Nephrology Pathology, Monash Medical Centre, Melbourne, Victoria, Australia
    Nephrology (Carlton) 16:704-9. 2011
    ..We aim to evaluate the effect of exercise on albuminuria in subjects at various stages of diabetic nephropathy in comparison with healthy control volunteers...
  24. ncbi request reprint Cardiovascular risk in dialysis patients: a comparison of risk factors and cardioprotective therapy between 1996 and 2001
    Fiona Y F Chow
    Department of Nephrology, Monash Medical Centre, 246 Clayton Road, Clayton, Victoria 3168, Australia
    Nephrology (Carlton) 8:177-83. 2003
    ..Proof of efficacy of these agents in this population of enormous risk is urgently required...
  25. ncbi request reprint Epidemiology of vascular access in the Australian hemodialysis population
    Kevan R Polkinghorne
    Department of Nephrology, Monash Medical Centre, Melbourne, Victoria, Australia
    Kidney Int 64:1893-902. 2003
    ..However, no data are available regarding these factors in a hemodialysis population where AVF utilization is high...
  26. doi request reprint Body composition in home haemodialysis versus conventional haemodialysis: a cross-sectional, matched, comparative study
    Rebecca Pellicano
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Nephrol Dial Transplant 25:568-73. 2010
    ..Nutritional status predicts outcome in dialysis populations. Increased dialysis time and/or frequency reportedly improves nutritional status. We examined the impact of more intensive dialysis on body composition...
  27. doi request reprint Secular trends in cardiovascular mortality rates of patients receiving dialysis compared with the general population
    Matthew A Roberts
    Department of Nephrology, Austin Health, Melbourne, Australia
    Am J Kidney Dis 58:64-72. 2011
    ..We hypothesized that cardiovascular mortality rates in dialysis patients, which are higher than in the general population, have not decreased as much as those in the general population...
  28. doi request reprint Dialysis modality, vascular access and mortality in end-stage kidney disease: A bi-national registry-based cohort study
    Jessica Kasza
    Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia
    Nephrology (Carlton) 21:878-86. 2016
    ..We compare the survival of patients undergoing home haemodialysis (HD) with a permanent vascular access, facility HD with a permanent vascular access, facility HD with a central venous catheter or peritoneal dialysis...
  29. ncbi request reprint Prevalence of albuminuria in Australia: the AusDiab Kidney Study
    Robert C Atkins
    Department of Nephrology, Monash Medical Centre, Victoria, Australia
    Kidney Int Suppl . 2004
    ..4, microalbuminuria 3.4 to 34, macroalbuminuria > 34)...
  30. doi request reprint Blood pressure and blood volume: acute and chronic considerations in hemodialysis
    Michelle C Lewicki
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Semin Dial 26:62-72. 2013
    ..This review explores the relationship of blood volume to blood pressure and potential targets for management in this at risk population...
  31. ncbi request reprint Population prevalence of albuminuria in the Australian Diabetes, Obesity, and Lifestyle (AusDiab) study: immunonephelometry compared with high-performance liquid chromatography
    Kevan R Polkinghorne
    Department of Nephrology, Monash Medical Centre, Victoria, Australia
    Am J Kidney Dis 47:604-13. 2006
    ..Standard immunochemical urinary albumin assays detect immunoreactive albumin, whereas high-performance liquid chromatography (HPLC) detects both immunoreactive and immunounreactive albumin...
  32. ncbi request reprint Time and exercise improve phosphate removal in hemodialysis patients
    Indralingam Vaithilingam
    Department of Nephrology, Monash Medical Centre, Clayton, Vic, Australia
    Am J Kidney Dis 43:85-9. 2004
    ..Control of serum phosphate remains a difficult clinical issue in most hemodialysis (HD) patients. This study examines 2 nonpharmacological approaches to improving phosphate control in HD patients...
  33. ncbi request reprint Comparison between different dialysate calcium concentrations in nocturnal hemodialysis
    Nigel D Toussaint
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia, and Department of Renal Medicine, Geelong Hospital, Geelong, Victoria, Australia
    Hemodial Int 11:217-24. 2007
    ..With concerns that prolonged higher Ca levels contribute to increased cardiovascular mortality, the optimal Ca dialysate bath is still unknown and further studies addressing bone metabolism with larger NHD numbers are required...
  34. doi request reprint Low versus high dialysate calcium concentration in alternate night nocturnal hemodialysis: A randomized controlled trial
    Rosemary Masterson
    Department of Nephrology, The Royal Melbourne Hospital, Parkville, Victoria, Australia
    Hemodial Int . 2016
    ..An important finding was the potential impact of alternate night NHD in attenuating progression of VC and inducing stabilisation of LVMI and PWV...
  35. ncbi request reprint Measurement of vascular calcification using CT fistulograms
    Nigel D Toussaint
    Department of Nephrology, Monash Medical Centre, 246 Clayton Road, Clayton, Victoria 3168, Australia
    Nephrol Dial Transplant 22:484-90. 2007
    ..No study to date has combined the CT fistulogram with concurrent determination of VC...
  36. doi request reprint Different faces of Nocardia infection in renal transplant recipients
    Shailendra Shrestha
    Department of Nephrology, Monash Medical Centre, Melbourne, Victoria, Australia
    Nephrology (Carlton) 21:254-60. 2016
    ..Nocardia infections are an uncommon but important cause of morbidity and mortality in renal transplant recipients. The present study was carried out to determine the spectrum of Nocardia infections in a renal transplant centre in Australia...
  37. pmc The Omega-3 fatty acids (Fish Oils) and Aspirin in Vascular access OUtcomes in REnal Disease (FAVOURED) study: the updated final trial protocol and rationale of post-initiation trial modifications
    Andrea K Viecelli
    Department of Nephrology, Princess Alexandra Hospital, Brisbane, QLD, Australia
    BMC Nephrol 16:89. 2015
    ..Publication of new evidence derived from additional studies of clopidogrel and a high screen failure rate due to prevalent aspirin usage prompted an updated trial design...
  38. doi request reprint Debate: Should dialysis at home be mandatory for all suitable ESRD patients?: home-based dialysis therapies are the second choice after transplantation
    Michelle C Lewicki
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia Department of Medicine, Monash University, Clayton, Victoria, Australia
    Semin Dial 28:147-54. 2015
    ..With patient-centered care an increasingly important aspect of our decision making paradigm, home-based dialysis should be considered as the default option in all patients transitioning to renal replacement therapy...
  39. pmc The association between body mass index and mortality in incident dialysis patients
    Sunil V Badve
    Department of Nephrology, Princess Alexandra Hospital, Brisbane, Queensland, Australia
    PLoS ONE 9:e114897. 2014
    ..To study the body mass index (BMI) trajectory in patients with incident end-stage kidney disease and its association with all-cause mortality...
  40. doi request reprint Early pancreas allograft thrombosis
    Sharmila Ramessur Chandran
    Department of Nephrology, Monash Medical Centre, Clayton, Vic, Australia
    Clin Transplant 27:410-6. 2013
    ..Multiple risk factors have been postulated. We hypothesized that recipient perioperative hypotension was a major risk factor and evaluated the correlation of this and other parameters with EPAT...
  41. doi request reprint Water quality in conventional and home haemodialysis
    Matthew J Damasiewicz
    Department of Nephrology, Monash Medical Centre, Locked Bag 29, Clayton, VIC 3168, Australia
    Nat Rev Nephrol 8:725-34. 2012
    ..These new machines have an increased emphasis on water conservation and recycling along with a decreased need for a complex infrastructure for water purification and maintenance...
  42. doi request reprint Intra-dialytic hypotension and blood volume and blood temperature monitoring
    Matthew J Damasiewicz
    Department of Nephrology, Monash Medical Centre, Monash University, Clayton, Victoria, Australia
    Nephrology (Carlton) 16:13-8. 2011
    ..We review the clinical utility of these technologies and summarize the current evidence of their effect on reducing the incidence of IDH in haemodialysis population...
  43. ncbi request reprint Adherence to guidelines for prevention of postsplenectomy sepsis. Age and sex are risk factors: a five-year retrospective review
    Despina Kotsanas
    Department of Infectious Diseases, Monash Medical Centre, Melbourne, Victoria, Australia
    ANZ J Surg 76:542-7. 2006
    ..Vaccination, education and use of long-term antibiotics are recommended in expert guidelines for the prevention of infectious complications after splenectomy. However, studies outside Australia have shown poor adherence to the guidelines...
  44. doi request reprint Predicting 6-month mortality risk of patients commencing dialysis treatment for end-stage kidney disease
    Sara E Ivory
    Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia
    Nephrol Dial Transplant . 2017
    ..We aimed to develop a tool for predicting patient mortality in the early stages of receiving dialysis...
  45. doi request reprint Water-soluble vitamin levels in extended hours hemodialysis
    Natalie Coveney
    Department of Nephrology, Monash Medical Centre, Victoria, AustraliaDepartment of Medicine, Monash University Clayton, Victoria, Australia
    Hemodial Int 15:30-8. 2011
    ..It also supports an ongoing role for multivitamin supplementation in conventional hemodialysis patients...
  46. doi request reprint Defining the relationship between average glucose and HbA1c in patients with type 2 diabetes and chronic kidney disease
    Clement Lo
    Monash Applied Research Stream, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia Diabetes and Vascular Medicine Unit, Monash Health, Melbourne, Australia
    Diabetes Res Clin Pract 104:84-91. 2014
    ..To examine the relationship between average glucose (AG) and HbA1c in patients with and without chronic kidney disease (CKD) and type 2 diabetes...
  47. ncbi request reprint Pharmacokinetic studies of dalteparin (Fragmin), enoxaparin (Clexane), and danaparoid sodium (Orgaran) in stable chronic hemodialysis patients
    Kevan R Polkinghorne
    Department of Nephrology, Royal Melbourne Hospital, Parkville, Victoria, Australia
    Am J Kidney Dis 40:990-5. 2002
    ..We performed a prospective randomized study of the pharmacokinetics of dalteparin and enoxaparin plus danaparoid in 21 hemodialysis patients...
  48. ncbi request reprint Detection and measurement of urinary protein
    Kevan R Polkinghorne
    Department of Nephrology, Monash Medical Centre, Victoria, Australia
    Curr Opin Nephrol Hypertens 15:625-30. 2006
    ..Accurate assessment is vital to enable detection and management of the patient with proteinuria...
  49. doi request reprint Home hemodialysis in Australia: current perspective
    Peter G Kerr
    Monash Medical Centre and Monash University, Clayton, Victoria, Australia
    Hemodial Int 12:S6-10. 2008
    ....
  50. ncbi request reprint Trends in hemodialysis vascular access from the Australia and New Zealand Dialysis and Transplant Registry (ANZDATA) 2000 to 2005
    Louise M Moist
    Division of Nephrology, London Health Sciences Center, University of Western Ontario, London, Ontario, Canada
    Am J Kidney Dis 50:612-21. 2007
    ..Australia historically has been recognized for its high fistula use...
  51. ncbi request reprint Implementing iron management clinical practice guidelines in patients with chronic kidney disease having dialysis
    Michelle J Irving
    Centre for Kidney Research, The Children s Hospital at Westmead, Sydney, NSW, Australia
    Med J Aust 185:310-4. 2006
    ..To evaluate the outcomes of and barriers to implementing standard guidelines (Caring for Australasians with renal impairment [CARI]), using iron management in patients having dialysis as an example...
  52. pmc Socioeconomic disadvantage and kidney disease in the United States, Australia, and Thailand
    Sarah L White
    George Institute, Sydney, NSW, Australia
    Am J Public Health 98:1306-13. 2008
    ..We sought to determine whether an elevated burden of chronic kidney disease is found among disadvantaged groups living in the United States, Australia, and Thailand...