Dianne P Stephens
Affiliation: Northern Territory
- Exploring pathways to improve indigenous organ donationD Stephens
Department of Health and Community Services, LifeNet NT, Northern Territory, Australia
Intern Med J 37:713-6. 2007..Equity of access is important. Cultural competence of requestors is important. Consultation, communication and education are the way forward...
- A clinical audit of the efficacy of tegaserod as a prokinetic agent in the intensive care unitDianne P Stephens
Royal Darwin Hospital, Darwin, NT, Australia
Crit Care Resusc 9:148-50. 2007..To formally document the effectiveness of tegaserod as a prokinetic agent in intensive care patients...
- Randomized, double-blind, placebo-controlled trial of granulocyte colony-stimulating factor in patients with septic shockDianne P Stephens
Intensive Care, Royal Darwin Hospital, Darwin, Australia
Crit Care Med 36:448-54. 2008..To investigate the effect of early administration of granulocyte colony-stimulating factor (G-CSF) on hospital mortality in nonneutropenic patients with septic shock, excluding patients with melioidosis...
- An audit of the use of granulocyte colony-stimulating factor in septic shockD P Stephens
Royal Darwin Hospital, Tiwi, Northern Territory, Australia
Intern Med J 32:143-8. 2002..In septic shock, the immune system can be considered one of the failing organ systems. G-CSF improves immune function and may be a useful adjunctive therapy in patients with septic shock...
- An observational cohort study of the kynurenine to tryptophan ratio in sepsis: association with impaired immune and microvascular functionChristabelle J Darcy
Global Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, Northern Territory, Australia
PLoS ONE 6:e21185. 2011..0001). IDO-mediated tryptophan catabolism is associated with dysregulated immune responses and impaired microvascular reactivity in sepsis and may link these two fundamental processes in sepsis pathophysiology...
- Asymmetric dimethylarginine, endothelial nitric oxide bioavailability and mortality in sepsisJoshua S Davis
International Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, Northern Territory, Australia
PLoS ONE 6:e17260. 2011....
- Sepsis-associated microvascular dysfunction measured by peripheral arterial tonometry: an observational studyJoshua S Davis
International Health Division, Menzies School of Health Research and Charles Darwin University, Rocklands Drive, Darwin, NT 0810, Australia
Crit Care 13:R155. 2009....
- Adjunctive granulocyte colony-stimulating factor for treatment of septic shock due to melioidosisAllen C Cheng
Menzies School of Health Research, Royal Darwin Hospital, Northern Territory Clinical School, Flinders University, Casuarina NT, Darwin, Australia
Clin Infect Dis 38:32-7. 2004..We conclude that G-CSF may have contributed to the reduction in the mortality rate among patients with septic shock due to melioidosis...
- A randomized controlled trial of granulocyte colony-stimulating factor for the treatment of severe sepsis due to melioidosis in ThailandAllen C Cheng
Menzies School of Health Research, Charles Darwin University, Darwin, Australia
Clin Infect Dis 45:308-14. 2007..Melioidosis is a tropical infectious disease associated with significant mortality. Most deaths occur early and are caused by fulminant sepsis...
- Angiopoietin-2 is increased in sepsis and inversely associated with nitric oxide-dependent microvascular reactivityJoshua S Davis
International Health Division, Menzies School of Health Research and Charles Darwin University, Ellengowan Drive, Casuarina, Darwin, NT 0810, Australia
Crit Care 14:R89. 2010..Nitric oxide (NO) inhibits WPB exocytosis, and bioavailability of endothelial NO is decreased in sepsis. We hypothesized that endothelial NO bioavailability would be inversely correlated with ang-2 concentrations in sepsis...
- Sepsis in the tropical Top End of Australia's Northern Territory: disease burden and impact on Indigenous AustraliansJoshua S Davis
Royal Darwin Hospital, Darwin, NT joshua davisATmenzies edu au
Med J Aust 194:519-24. 2011....
- Outcomes of patients with melioidosis treated with meropenemAllen C Cheng
Menzies School of Health Research, Charles Darwin University, Casuarina NT 0811, Northern Territory, Darwin, Australia
Antimicrob Agents Chemother 48:1763-5. 2004..The use of meropenem may be associated with improved outcomes in patients with severe sepsis associated with melioidosis...
- Melioidosis Causing Critical Illness: A Review of 24 Years of Experience From the Royal Darwin Hospital ICUDianne P Stephens
1Department of Intensive Care, Royal Darwin Hospital, Darwin, NT, Australia 2Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT, Australia 3Department of Infectious Diseases and Northern Territory Medical Program, Royal Darwin Hospital, Darwin, NT, Australia
Crit Care Med 44:1500-5. 2016..This review describes the demographics, management, and outcomes of a large cohort of critically ill patients with melioidosis...
- Particulate face masks for protection against airborne pathogens - one size does not fit all: an observational studySusan Winter
Intensive Care Department, Royal Darwin Hospital, Darwin, NT, USA
Crit Care Resusc 12:24-7. 2010..To determine the proportion of hospital staff who pass fit tests with each of three commonly used particulate face masks, and factors influencing preference and fit test results...
- Murray Valley encephalitis in an adult traveller complicated by long-term flaccid paralysis: case report and review of the literatureMark W Douglas
Royal Darwin Hospital, PO Box 41326, Casuarina, NT 0811, Australia
Trans R Soc Trop Med Hyg 101:284-8. 2007..Our case highlights the potential severity of flavivirus-induced encephalitis and the importance of avoiding mosquito bites while travelling through endemic areas...
- Ethical problems of evaluating a new treatment for melioidosisAllen C Cheng
Menzies School of Health Research and Northern Territory Clinical School, Flinders University, PO Box 41096, Casuarina NT 0811, Darwin, Australia
BMJ 327:1280-2. 2003
- Leptospirosis: an unusual presentationJane H Thomas
Department of Intensive Care, Royal Darwin Hospital, Darwin, NT, Australia
Crit Care Resusc 8:215-8. 2006..This case highlights the multiple factors that should prompt health care workers to consider the diagnosis of leptospirosis in non-classical presentations...
- Severe falciparum malaria in five soldiers from East Timor: a case series and literature reviewP G Blum
Intensive Care Unit, Royal Darwin Hospital, Northern Territory
Anaesth Intensive Care 29:426-34. 2001..This article discusses the current controversies of exchange blood transfusion and the use of the new artemisinin derivatives...
- Fatal community-associated methicillin-resistant Staphylococcus aureus pneumonia after influenzaSteven Y C Tong
Med J Aust 188:61. 2008
- Comment on "Terlipressin in chronic hyperdynamic endotoxic shock: is it safe?" by P. AsfarBart L De Keulenaer
Intensive Care Med 29:854; author reply 855. 2003