David A Mackey

Summary

Country: Australia

Publications

  1. doi request reprint The 'I' in personalized genetics: 2008 Ian Constable lecture
    David A Mackey
    Centre for Ophthalmology and Visual Science, University of Western Australia, Lions Eye Institute, Perth, Western Australia
    Clin Exp Ophthalmol 37:434-43. 2009
  2. doi request reprint Comparison of monochromatic aberrations in young adults with different visual acuity and refractive errors
    Seyhan Yazar
    From the University of Western Australia Centre for Ophthalmology and Visual Science and Lions Eye Institute Yazar, Hewitt, Forward, McKnight, Tan, Mackey and the Telethon Institute for Child Health Research Mountain, Perth, Western Australia, Australia Electronic address
    J Cataract Refract Surg 40:441-9. 2014
  3. doi request reprint Pterygium and conjunctival ultraviolet autofluorescence in young Australian adults: the Raine study
    Charlotte M McKnight
    Lions Eye Institute, Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth, Australia
    Clin Experiment Ophthalmol 43:300-7. 2015
  4. pmc Genetic and environmental factors in conjunctival UV autofluorescence
    Seyhan Yazar
    Centre for Ophthalmology and Vision Science Lions Eye Institute Perth, University of Western Australia, Perth, Australia
    JAMA Ophthalmol 133:406-12. 2015
  5. pmc Myopia in young adults is inversely related to an objective marker of ocular sun exposure: the Western Australian Raine cohort study
    Charlotte M McKnight
    Centre for Ophthalmology and Visual Science, University of Western Australia, Lions Eye Institute, Perth, Australia Electronic address
    Am J Ophthalmol 158:1079-85. 2014
  6. doi request reprint Myopia is associated with lower vitamin D status in young adults
    Seyhan Yazar
    Centre for Ophthalmology and Vision Science, University of Western Australia and the Lions Eye Institute, Perth, Western Australia, Australia
    Invest Ophthalmol Vis Sci 55:4552-9. 2014
  7. doi request reprint Distribution of astigmatism as a function of age in an Australian population
    Paul G Sanfilippo
    Centre for Ophthalmology and Visual Science, Lions Eye Institute, University of Western Australia, Perth, Western Australia, Australia
    Acta Ophthalmol 93:e377-85. 2015
  8. pmc Quantification of sun-related changes in the eye in conjunctival ultraviolet autofluorescence images
    Emily Huynh
    University of Western Australia, Centre for Ophthalmology and Visual Science, Lions Eye Institute, 2 Verdun Street, Nedlands, Perth, Western Australia 6009, Australia
    J Med Imaging (Bellingham) 3:034001. 2016
  9. doi request reprint Early Anesthesia Exposure and the Effect on Visual Acuity, Refractive Error, and Retinal Nerve Fiber Layer Thickness of Young Adults
    Seyhan Yazar
    Center for Ophthalmology and Visual Science, University of Western Australia, Lions Eye Institute, Perth, Western Australia, Australia
    J Pediatr 169:256-9.e1. 2016
  10. doi request reprint Swimming goggle wear is not associated with an increased prevalence of glaucoma
    Maria Franchina
    Centre for Ophthalmology and Visual Science, University of Western Australia and Lions Eye Institute, Perth, Western Australia, Australia
    Br J Ophthalmol 99:255-7. 2015

Collaborators

  • Minas T Coroneo
  • Jenny A Mountain
  • Jamie E Craig
  • Fred K Chen
  • Kathryn P Burdon
  • Caleb Ing
  • Stuart Macgregor
  • Ian L McAllister
  • Phillip E Melton
  • Seyhan Yazar
  • Alex W Hewitt
  • Charlotte M McKnight
  • Paul G Sanfilippo
  • Hannah Forward
  • Justin C Sherwin
  • Sue Ling Wan
  • Maria Franchina
  • Craig E Pennell
  • Danuta M Bukowska
  • Emily Huynh
  • Anne Marie E Yardley
  • Lisa Booth
  • Alex X Tan
  • Nina S McCarthy
  • Alex Tan
  • Ivy Tang
  • Avenell L Chew
  • Enid Chelva
  • Ajmal Mian
  • Geoffrey C Lam
  • Annette K Hoskin
  • Angela Jacques
  • Britta S von Ungern-Sternberg
  • Kate Hanman
  • Min H Kang
  • Kay Cox
  • Jonathan B Ruddle
  • David Turton
  • Pippa Byrd
  • Valerie Hiew
  • Gu Zhu
  • Johnson Hong
  • Leonel Ximenes Barbosa
  • Danny Tu
  • Elliot Smith
  • Piriya Quach-Thanissorn
  • Sonia Gengatharen
  • Lisa Kearns
  • Colleen H Wilkinson
  • Nicholas G Martin
  • Joanna Ward
  • Gabriel Cuellar-Partida
  • Eric K Moses
  • Wendy H Oddy
  • Robyn M Lucas
  • George E C Gooden
  • Lucinda J Black
  • Terri L Young
  • Gemma Cadby
  • Wei Ang
  • Alla Soloshenko
  • Sandra K Oates
  • Diane Wood

Detail Information

Publications22

  1. doi request reprint The 'I' in personalized genetics: 2008 Ian Constable lecture
    David A Mackey
    Centre for Ophthalmology and Visual Science, University of Western Australia, Lions Eye Institute, Perth, Western Australia
    Clin Exp Ophthalmol 37:434-43. 2009
    ..However, as identical twins show us, for some conditions our genes do not absolutely determine our destiny and environmental factors interact with our genetic profile...
  2. doi request reprint Comparison of monochromatic aberrations in young adults with different visual acuity and refractive errors
    Seyhan Yazar
    From the University of Western Australia Centre for Ophthalmology and Visual Science and Lions Eye Institute Yazar, Hewitt, Forward, McKnight, Tan, Mackey and the Telethon Institute for Child Health Research Mountain, Perth, Western Australia, Australia Electronic address
    J Cataract Refract Surg 40:441-9. 2014
    ..To compare the monochromatic aberrations in a large cohort of 20-year-old Australians with differing levels of visual acuity and explore the relationship between these aberrations and refractive error...
  3. doi request reprint Pterygium and conjunctival ultraviolet autofluorescence in young Australian adults: the Raine study
    Charlotte M McKnight
    Lions Eye Institute, Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth, Australia
    Clin Experiment Ophthalmol 43:300-7. 2015
    ..Conjunctival ultraviolet autofluorescence, a biomarker of ocular sun exposure, has recently been characterized in some Australian populations...
  4. pmc Genetic and environmental factors in conjunctival UV autofluorescence
    Seyhan Yazar
    Centre for Ophthalmology and Vision Science Lions Eye Institute Perth, University of Western Australia, Perth, Australia
    JAMA Ophthalmol 133:406-12. 2015
    ..Hence, CUVAF has excellent potential as an objective biomarker of sun exposure. However, much variation in CUVAF has been observed, and the relative contributions of genes and environment to this variation have not yet been identified...
  5. pmc Myopia in young adults is inversely related to an objective marker of ocular sun exposure: the Western Australian Raine cohort study
    Charlotte M McKnight
    Centre for Ophthalmology and Visual Science, University of Western Australia, Lions Eye Institute, Perth, Australia Electronic address
    Am J Ophthalmol 158:1079-85. 2014
    ..To determine the association between ocular sun exposure measured by conjunctival ultraviolet (UV) autofluorescence and myopic refractive error in young adults...
  6. doi request reprint Myopia is associated with lower vitamin D status in young adults
    Seyhan Yazar
    Centre for Ophthalmology and Vision Science, University of Western Australia and the Lions Eye Institute, Perth, Western Australia, Australia
    Invest Ophthalmol Vis Sci 55:4552-9. 2014
    ..To investigate the association between serum vitamin D levels and myopia in young adults...
  7. doi request reprint Distribution of astigmatism as a function of age in an Australian population
    Paul G Sanfilippo
    Centre for Ophthalmology and Visual Science, Lions Eye Institute, University of Western Australia, Perth, Western Australia, Australia
    Acta Ophthalmol 93:e377-85. 2015
    ..We aimed to assess the association between astigmatism and age to identify appropriate age cut-offs for maximizing power in genetic studies of astigmatism...
  8. pmc Quantification of sun-related changes in the eye in conjunctival ultraviolet autofluorescence images
    Emily Huynh
    University of Western Australia, Centre for Ophthalmology and Visual Science, Lions Eye Institute, 2 Verdun Street, Nedlands, Perth, Western Australia 6009, Australia
    J Med Imaging (Bellingham) 3:034001. 2016
    ..Algorithm performance was compared to manual measurements and yielded better than 95% correspondence in both intra- and interobserver agreement. Furthermore, the semiautomatic method significantly reduced analysis time by 50%. ..
  9. doi request reprint Early Anesthesia Exposure and the Effect on Visual Acuity, Refractive Error, and Retinal Nerve Fiber Layer Thickness of Young Adults
    Seyhan Yazar
    Center for Ophthalmology and Visual Science, University of Western Australia, Lions Eye Institute, Perth, Western Australia, Australia
    J Pediatr 169:256-9.e1. 2016
    ..To investigate whether being anesthesia administered at least once in early life influenced 3 main proxies of visual function: visual acuity, refractive error, and optic nerve health in young adulthood...
  10. doi request reprint Swimming goggle wear is not associated with an increased prevalence of glaucoma
    Maria Franchina
    Centre for Ophthalmology and Visual Science, University of Western Australia and Lions Eye Institute, Perth, Western Australia, Australia
    Br J Ophthalmol 99:255-7. 2015
    ..The aim of this study was to determine if glaucoma prevalence is increased among adult swimmers...
  11. doi request reprint Do recycled spectacles meet the refractive needs of a developing country?
    Sue Ling Wan
    Centre for Ophthalmology and Visual Sciences, University of Western Australia Lions Eye Institute, Perth, Western Australia, Australia
    Clin Exp Optom 98:177-82. 2015
    ..The aim was to compare the power of spectacles donated to a recycled spectacle program to the custom-made spectacle refractive prescriptions dispensed in a developing country...
  12. ncbi request reprint Ferritin light chain gene mutation in a large Australian family with hereditary hyperferritinemia-cataract syndrome
    Seyhan Yazar
    a Centre for Ophthalmology and Visual Science Lions Eye Institute, University of Western Australia, Perth, Western Australia, Australia
    Ophthalmic Genet . 2016
    ..We present an FTL mutation in an Australian family with 10 HHCS-affected members spanning three generations...
  13. doi request reprint The Importance of Conditional Probability in Diagnostic Reasoning and Clinical Decision Making: A Primer for the Eye Care Practitioner
    Paul G Sanfilippo
    a Centre for Ophthalmology and Visual Science, University of Western Australia, Lions Eye Institute, Perth, Australia
    Ophthalmic Epidemiol . 2017
    ..To outline and detail the importance of conditional probability in clinical decision making and discuss the various diagnostic measures eye care practitioners should be aware of in order to improve the scope of their clinical practice...
  14. pmc Meta-analysis of human methylation data for evidence of sex-specific autosomal patterns
    Nina S McCarthy
    Centre for the Genetic Origins of Health and Disease GOHaD, University of Western Australia, Perth, Australia
    BMC Genomics 15:981. 2014
    ..We collectively analysed 76 published studies (nā€‰=ā€‰6,795) for sex-associated differences in both autosomal and sex chromosome CpG sites...
  15. pmc Benchmarking undedicated cloud computing providers for analysis of genomic datasets
    Seyhan Yazar
    Centre for Ophthalmology and Visual Science, University of Western Australia, Lions Eye Institute, Perth, Western Australia, Australia
    PLoS ONE 9:e108490. 2014
    ..In addition to releasing our cost-effectiveness comparison, we present available ready-to-use scripts for establishing Hadoop instances with Ganglia monitoring on EC2 or GCE. ..
  16. doi request reprint Raine eye health study: design, methodology and baseline prevalence of ophthalmic disease in a birth-cohort study of young adults
    Seyhan Yazar
    Centre for Ophthalmology and Visual Science, University of Western Australia, Lions Eye Institute Perth, Australia
    Ophthalmic Genet 34:199-208. 2013
    ..This article summarizes the rationale and study design of REHS and outlines the baseline prevalence of ophthalmic disease in this population...
  17. doi request reprint Paediatric ocular and adnexal injuries requiring hospitalisation in Western Australia
    Anne Marie E Yardley
    Lions Eye Institute, Perth, Western Australia, Australia
    Clin Exp Optom . 2016
    ..The aim was to investigate the characteristics and outcomes of ocular and adnexal injuries requiring hospitalisation in children in Perth, Western Australia...
  18. doi request reprint FUNDUS AUTOFLUORESCENCE IN RUBELLA RETINOPATHY: Correlation With Photoreceptor Structure and Function
    Danuta M Bukowska
    Centre for Ophthalmology and Visual Science, Lions Eye Institute, The University of Western Australia, Western Australia Department of Ophthalmology, Royal Perth Hospital, Perth, Western Australia and Department of Medical Technology and Physics, Sir Charles Gairdner Hospital, Perth, Western Australia
    Retina 37:124-134. 2017
    ..To illustrate altered fundus autofluorescence in rubella retinopathy and to investigate their relationships with photoreceptor structure and function using multimodal imaging...
  19. doi request reprint Gene-Based Therapies for Leber Hereditary Optic Neuropathy. Hype or Hope?
    David A Mackey
    From the Lions Eye Institute, Centre for Ophthalmology and Visual Science, University of Western Australia, Perth Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, University of Melbourne, Melbourne and School of Medicine, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia
    Asia Pac J Ophthalmol (Phila) 5:253-5. 2016
    ....
  20. doi request reprint Genome-wide association study success in ophthalmology
    David A Mackey
    aLions Eye Institute, Centre for Ophthalmology and Visual Science, University of Western Australia, Perth, Western Australia bCentre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, University of Melbourne, Melbourne, Victoria cSchool of Medicine, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia
    Curr Opin Ophthalmol 25:386-93. 2014
    ..We highlight key recent discoveries using the genome-wide association study design...
  21. doi request reprint Don't it make your brown eyes blue? A comparison of iris colour across latitude in Australian twins
    Paul G Sanfilippo
    Lions Eye Institute, Centre for Ophthalmology and Visual Science, University of Western Australia, Perth, Australia Centre for Eye Research Australia, University of Melbourne, Department of Ophthalmology, Royal Victorian Eye and Ear Hospital, Melbourne, Australia
    Clin Exp Optom 98:172-6. 2015
    ..The aim was to determine whether latitudinal (Queensland versus Tasmania) variation in reported disease frequency in Australia may be biased by differences in population...
  22. doi request reprint Missing X and Y: a review of participant ages in population-based eye studies
    Hannah Forward
    Lions Eye Institute, Centre for Ophthalmology and Visual Science, University of Western Australia, 2 Verdun Street, Nedlands, WA 6009, Australia
    Clin Experiment Ophthalmol 40:305-19. 2012
    ..No studies specifically examined young adults. Twenty-six per cent of studies included young adults as part of all ages examined but none of these examined a large number of young adults...