D P Chew
Affiliation: Flinders University
- Invasive management and late clinical outcomes in contemporary Australian management of acute coronary syndromes: observations from the ACACIA registryDerek P Chew
Flinders University, Adelaide, SA
Med J Aust 188:691-7. 2008..To describe the impact of invasive management on 12-month survival among patients with suspected acute coronary syndrome (ACS) in Australia...
- Condition-specific Streaming versus an Acuity-based Model of Cardiovascular Care: A Historically-controlled Quality Improvement Study Evaluating the Association with Early Clinical EventsDerek P Chew
School of Medicine, Flinders University of South Australia, Adelaide, SA, Australia Department of Cardiovascular Medicine, Southern Adelaide Local Health Network, Adelaide, SA, Australia Health Systems Research, South Australian Health and Medical Research Institute, Adelaide, SA, Australia Electronic address
Heart Lung Circ 25:19-28. 2016..We prospectively explored the clinical and health service implications of a "condition-based" redesign in cardiac care delivery, rather than acuity-based, within a tertiary hospital...
- High sensitivity-troponin elevation secondary to non-coronary diagnoses and death and recurrent myocardial infarction: An examination against criteria of causalityDerek P Chew
School of Medicine, Flinders University of South Australia, Australia
Eur Heart J Acute Cardiovasc Care 4:419-28. 2015..We examined the causal relationship between troponin elevation in non-coronary diagnoses and late cardiac events using the Bradford Hills criteria for causality...
- Bivalirudin in percutaneous coronary interventionSam J Lehman
Department of Medicine, Flinders University, South Australia, Australia
Vasc Health Risk Manag 2:357-63. 2006..There are now data from multiple clinical trials and meta-analyses in the setting of ACS and PCI. Early results from the acute catheterization and urgent intervention strategy (ACUITY) trial are discussed...
- Impact of a regionalised clinical cardiac support network on mortality among rural patients with myocardial infarctionPhilip A Tideman
Country Health, Adelaide, SA, Australia
Med J Aust 200:157-60. 2014..To evaluate the impact of the regionalised Integrated Cardiovascular Clinical Network (ICCNet) on 30-day mortality among patients with myocardial infarction (MI) in an Australian rural setting...
- Acute coronary syndrome care across Australia and New Zealand: the SNAPSHOT ACS studyDerek P Chew
Department of Cardiovascular Medicine, Flinders University, Adelaide, SA
Med J Aust 199:185-91. 2013..To characterise management of suspected acute coronary syndrome (ACS) in Australia and New Zealand, and to assess the application of recommended therapies according to published guidelines...
- Perceived risk of ischemic and bleeding events in acute coronary syndromesDerek P Chew
Department of Cardiology, Flinders University, Flinders Medical Centre, Adelaide, SA 5042, Australia
Circ Cardiovasc Qual Outcomes 6:299-308. 2013..Acute coronary syndrome registries report the use of incomplete guideline therapies, especially among the highest risk patients. Whether this treatment gap results from misperceptions of risk by physicians is uncertain...
- Patterns of inflammatory activation associated with precipitants of acute coronary syndromes: a case-crossover studyD P Chew
Flinders University Flinders Medical Centre, Adelaide, South Australia, Australia
Intern Med J 42:1096-103. 2012..We sought to assess a broad array of possible precipitants of acute coronary syndromes (ACS) and evaluate their association with detectable inflammatory activation...
- Long-term antiplatelet therapy: from clinical trials to clinical applicationDerek P Chew
Flinders University, Adelaide, South Australia, Australia
Curr Opin Cardiol 27:347-54. 2012..This review seeks to describe the emerging clinical trial data that informs clinical practice with regards to dual antiplatelet therapy...
- Randomized trials of clinical networks in the management of ST-elevation MI: can they be performed?Derek P Chew
Flinders University, Flinders Medical Centre, South Australia, Australia
Curr Opin Cardiol 24:301-6. 2009..It is well established that the temporal window during which myocardial salvage may be achieved is limited...
- Potential survival gains in the treatment of myocardial infarctionD P Chew
Flinders University, Flinders Drive, Bedford Park, South Australia, 5042 Australia
Heart 95:1844-50. 2009..To evaluate the potential impact of complete implementation of guideline recommendations in myocardial infarction (MI) care, and contrast this with new innovations...
- Cost effectiveness of a general practice chronic disease management plan for coronary heart disease in AustraliaDerek P Chew
Flinders Medical Centre, Flinders University, Flinders Drive, Bedford Park, SA 5042, Australia
Aust Health Rev 34:162-9. 2010..The cost effectiveness of a general practice-based program for managing coronary heart disease (CHD) patients in Australia remains uncertain. We have explored this through an economic model...
- Six-month survival benefits associated with clinical guideline recommendations in acute coronary syndromesD P Chew
Department of Cardiovascular Medicine, Flinders University, Adelaide, South Australia, Australia
Heart 96:1201-6. 2010..The authors sought to define which guideline-advocated therapies are associated with the greatest benefit with respect to 6-month survival in patients hospitalised with an acute coronary syndrome (ACS)...
- The value of "more" information: the emerging role of novel diagnostic investigations in cardiovascular medicineDerek P Chew
Flinders University, Flinders Medical Centre, Flinders Drive, Bedford Park, South Australia 5042, Australia
Heart Lung Circ 18:114-7. 2009..To date many studies in this area have fallen short of demonstrating such benefits and it is our responsibility as a clinical community to demand more of such innovation...
- The last mile: improving patient outcomes within modern cardiovascular medicineDerek P Chew
Roy and Marjorie Edwards National Heart Foundation, Adelaide, SA, Australia
Heart Lung Circ 17:S10-3. 2008..This article will discuss some of issues faced in operationalizing "clinical effectiveness" in cardiovascular care in Australia...
- National data elements for the clinical management of acute coronary syndromesDerek P B Chew
Flinders Medical Centre, Bedford Park, Adelaide, SA 5042, Australia
Med J Aust 182:S1-14. 2005....
- Clinical end point definitions after percutaneous coronary intervention and their relationship to late mortality: an assessment by attributable riskD P Chew
Flinders University, Adelaide, South Australia, Australia
Heart 92:945-50. 2006..To explore the relative and absolute risks associated with various definitions for myocardial infarction, bleeding and revascularisation within the context of percutaneous coronary intervention (PCI)...
- Morbidity, mortality and economic burden of renal impairment in cardiac intensive careD P Chew
Flinders University, South Australia, Australia
Intern Med J 36:185-92. 2006..Moderate to severe impairment of renal function has emerged as a potent risk factor for adverse short- and long-term outcomes among patients presenting with cardiac disease...
- Current management of acute coronary syndromes in Australia: observations from the acute coronary syndromes prospective auditD P Chew
Department of Cardiology, Flinders University, Flinders Medical Centre, Adelaide, South Australia
Intern Med J 37:741-8. 2007..However, most of these data have been acquired outside the local context. We sought to describe the current patterns of ACS care in Australia...
- Patients with non-ST-elevation acute coronary syndromes undergoing coronary artery bypass grafting in the modern era of antithrombotic therapyDerek P Chew
Flinders Medical Centre, South Australia, Adelaide, Australia
Am Heart J 155:239-44. 2008..We explored the clinical outcomes among high-risk patients undergoing CABG and the impact of modern pharmacology...
- Coronary artery bypass surgery in patients with acute coronary syndromes is difficult to predictDerek P Chew
Flinders Medical Centre, Adelaide, Australia
Am Heart J 155:841-7. 2008..We assessed the ability to predict need for CABG from demographics known at the time of ACS presentation, using data from SYNERGY...
- Bivalirudin versus heparin and glycoprotein IIb/IIIa inhibition among patients with renal impairment undergoing percutaneous coronary intervention (a subanalysis of the REPLACE-2 trial)Derek P Chew
Department of Cardiovascular Medicine, Flinders Medical Centre, Bedford Park, South Australia, Australia
Am J Cardiol 95:581-5. 2005..The safety and efficacy of bivalirudin compared with heparin and planned glycoprotein IIb/IIIa inhibition in this high-risk group are comparable and consistent with the results of the overall trial...
- Improving the management of acute coronary syndromes in Australia: translating evidence to outcomesL T Huynh
Department of Medicine, Cardiovascular Outcomes Research Group and Flinders Centre for Clinical Change and Healthcare Research, Flinders University, Adelaide, South Australia
Intern Med J 37:412-5. 2007..This article reviews what we have learnt from previous quality improvement initiatives and discusses what we need to know to improve acute coronary syndromes management in Australia...
- Impact of age, gender and indigenous status on access to diagnostic coronary angiography for patients presenting with non-ST segment elevation acute coronary syndromes in AustraliaY L Roe
School of Health Sciences, University of South Australia, Adelaide, Australia
Intern Med J 43:317-22. 2013..Indigenous patients are younger and have poorer risk profiles, and represent a group that would benefit from greater investment in prevention strategies...
- The foundation and launch of the Melbourne Interventional Group: a collaborative interventional cardiology projectA E Ajani
Department of Cardiology, Royal Melbourne Hospital, Melbourne, Australia
Heart Lung Circ 15:44-7. 2006..The eventual goal of MIG is to provide a contemporary appraisal of Australian interventional cardiology practice, with opportunities to improve in-hospital and long-term outcomes of patients with coronary artery disease...
- Reperfusion therapy in the acute management of ST-segment-elevation myocardial infarction in Australia: findings from the ACACIA registryLuan T Huynh
Flinders University, Adelaide, SA, Australia
Med J Aust 193:496-501. 2010..To describe the contemporary management and outcomes of patients presenting with ST-segment-elevation myocardial infarction (STEMI) in Australia...
- Cost-effectiveness of drug-eluting stents: if only all things were equalDerek P B Chew
Med J Aust 182:376-7. 2005..They reduce rates of restenosis but not mortality or infarction--so are they worth it?..