J C Hurley

Summary

Affiliation: Ballarat Health Services
Country: Australia

Publications

  1. pmc World-wide variation in incidence of Acinetobacter associated ventilator associated pneumonia: a meta-regression
    James C Hurley
    Department of Rural Health, Melbourne Medical School, University of Melbourne, Ballarat, 3353, Australia
    BMC Infect Dis 16:577. 2016
  2. doi request reprint Impact of selective digestive decontamination on respiratory tract Candida among patients with suspected ventilator-associated pneumonia. A meta-analysis
    J C Hurley
    Department of Rural Health, Melbourne Medical School, University of Melbourne, Parkville, Australia
    Eur J Clin Microbiol Infect Dis 35:1121-35. 2016
  3. pmc Endotoxemia as a diagnostic tool for patients with suspected bacteremia caused by gram-negative organisms: a meta-analysis of 4 decades of studies
    James C Hurley
    Rural Health Academic Center, University of Melbourne, Melbourne, Australia Division of Internal Medicine, Ballarat Health Services, Ballarat, Victoria, Australia
    J Clin Microbiol 53:1183-91. 2015
  4. pmc Response to John G. Brock-Utne. Comment on Hurley, J.C. Towards Clinical Application of Anti-endotoxin Antibodies; A Re-Appraisal of the Disconnect
    James C Hurley
    Rural Health Academic Center, Melbourne Medical School, University of Melbourne, Parkville 3010, Australia
    Toxins (Basel) 6:1364-5. 2014
  5. pmc Towards clinical applications of anti-endotoxin antibodies; a re-appraisal of the disconnect
    James C Hurley
    Rural Health Academic Center, Melbourne Medical School, University of Melbourne, Parkville 3010, Australia
    Toxins (Basel) 5:2589-620. 2013
  6. pmc The perfidious effect of topical placebo: calibration of Staphylococcus aureus ventilator-associated pneumonia incidence within selective digestive decontamination studies versus the broader evidence base
    James C Hurley
    Rural Health Academic Center, Melbourne Medical School, University of Melbourne, Ballarat Health Services, and Infection Control Committees, St John of God Hospital and Ballarat Health Services, Ballarat, Victoria, Australia
    Antimicrob Agents Chemother 57:4524-31. 2013
  7. doi request reprint Meta-analysis of clinical studies of diagnostic tests: developments in how the receiver operating characteristic "works"
    James Hurley
    Rural Health Academic Centre, Melbourne Medical School, University of Melbourne, Ballarat, Victoria, Australia
    Arch Pathol Lab Med 135:1585-90. 2011
  8. doi request reprint Lack of impact of selective digestive decontamination on Pseudomonas aeruginosa ventilator-associated pneumonia: benchmarking the evidence base
    James C Hurley
    Rural Health Academic Centre, Melbourne Medical School, University of Melbourne, Ballarat 3350, Victoria, Australia
    J Antimicrob Chemother 66:1365-73. 2011
  9. pmc Paradoxical ventilator associated pneumonia incidences among selective digestive decontamination studies versus other studies of mechanically ventilated patients: benchmarking the evidence base
    James C Hurley
    Rural Health Academic Centre, Melbourne Medical School, The University of Melbourne, Dunvegan 806 Mair St, Ballarat, Victoria 3350, Australia
    Crit Care 15:R7. 2011
  10. doi request reprint Does gram-negative bacteraemia occur without endotoxaemia? A meta-analysis using hierarchical summary ROC curves
    J C Hurley
    School of Rural Health, University of Melbourne, Shepparton, Vic, Australia
    Eur J Clin Microbiol Infect Dis 29:207-15. 2010

Detail Information

Publications18

  1. pmc World-wide variation in incidence of Acinetobacter associated ventilator associated pneumonia: a meta-regression
    James C Hurley
    Department of Rural Health, Melbourne Medical School, University of Melbourne, Ballarat, 3353, Australia
    BMC Infect Dis 16:577. 2016
    ..The objective here is to define the extent and possible reasons for geographic variation for Acinetobacter associated VAP whether or not these isolates are reported as Acinetobacter baumanii...
  2. doi request reprint Impact of selective digestive decontamination on respiratory tract Candida among patients with suspected ventilator-associated pneumonia. A meta-analysis
    J C Hurley
    Department of Rural Health, Melbourne Medical School, University of Melbourne, Parkville, Australia
    Eur J Clin Microbiol Infect Dis 35:1121-35. 2016
    ..Several relationships have been identified. The increased incidence among concurrent control groups of SDD studies cannot be appreciated in any single study examined in isolation. ..
  3. pmc Endotoxemia as a diagnostic tool for patients with suspected bacteremia caused by gram-negative organisms: a meta-analysis of 4 decades of studies
    James C Hurley
    Rural Health Academic Center, University of Melbourne, Melbourne, Australia Division of Internal Medicine, Ballarat Health Services, Ballarat, Victoria, Australia
    J Clin Microbiol 53:1183-91. 2015
    ..coli (57% [40 to 73%]; P=0.55). Among studies of the sepsis patient group, the concordance of endotoxemia with GN bacteremia was surprisingly weak, especially for E. coli GN bacteremia...
  4. pmc Response to John G. Brock-Utne. Comment on Hurley, J.C. Towards Clinical Application of Anti-endotoxin Antibodies; A Re-Appraisal of the Disconnect
    James C Hurley
    Rural Health Academic Center, Melbourne Medical School, University of Melbourne, Parkville 3010, Australia
    Toxins (Basel) 6:1364-5. 2014
    ..I appreciate the thoughtful comments from Dr. Brock-Utne [1] on my recent review of the disconnect between animal studies and clinical experience with anti-endotoxemia therapies [2]. ..
  5. pmc Towards clinical applications of anti-endotoxin antibodies; a re-appraisal of the disconnect
    James C Hurley
    Rural Health Academic Center, Melbourne Medical School, University of Melbourne, Parkville 3010, Australia
    Toxins (Basel) 5:2589-620. 2013
    ..Fundamentally however, the disconnect not only remains, it has enlarged. ..
  6. pmc The perfidious effect of topical placebo: calibration of Staphylococcus aureus ventilator-associated pneumonia incidence within selective digestive decontamination studies versus the broader evidence base
    James C Hurley
    Rural Health Academic Center, Melbourne Medical School, University of Melbourne, Ballarat Health Services, and Infection Control Committees, St John of God Hospital and Ballarat Health Services, Ballarat, Victoria, Australia
    Antimicrob Agents Chemother 57:4524-31. 2013
    ..This effect of topical placebo is perfidious; it could contribute to the higher VAP incidence and inflate the apparent "effectiveness" of SDD. The SDD evidence base requires reappraisal. ..
  7. doi request reprint Meta-analysis of clinical studies of diagnostic tests: developments in how the receiver operating characteristic "works"
    James Hurley
    Rural Health Academic Centre, Melbourne Medical School, University of Melbourne, Ballarat, Victoria, Australia
    Arch Pathol Lab Med 135:1585-90. 2011
    ..Using current methodology, a meta-analysis on clinical studies of diagnostic tests can address questions relevant to the clinical application of a diagnostic test that cannot be answered at the level of the individual study...
  8. doi request reprint Lack of impact of selective digestive decontamination on Pseudomonas aeruginosa ventilator-associated pneumonia: benchmarking the evidence base
    James C Hurley
    Rural Health Academic Centre, Melbourne Medical School, University of Melbourne, Ballarat 3350, Victoria, Australia
    J Antimicrob Chemother 66:1365-73. 2011
    ..The objective here is to address these effects through a benchmarking analysis of the evidence base...
  9. pmc Paradoxical ventilator associated pneumonia incidences among selective digestive decontamination studies versus other studies of mechanically ventilated patients: benchmarking the evidence base
    James C Hurley
    Rural Health Academic Centre, Melbourne Medical School, The University of Melbourne, Dunvegan 806 Mair St, Ballarat, Victoria 3350, Australia
    Crit Care 15:R7. 2011
    ..However, the striking variability in ventilator associated pneumonia-incidence proportion (VAP-IP) among the SDD studies remains unexplained and a postulated contextual effect remains untested for...
  10. doi request reprint Does gram-negative bacteraemia occur without endotoxaemia? A meta-analysis using hierarchical summary ROC curves
    J C Hurley
    School of Rural Health, University of Melbourne, Shepparton, Vic, Australia
    Eur J Clin Microbiol Infect Dis 29:207-15. 2010
    ..These findings help to reconcile seemingly disparate study results...
  11. pmc Diagnosis of endotoxemia with gram-negative bacteremia is bacterial species dependent: a meta-analysis of clinical studies
    James C Hurley
    School of Rural Health, University of Melbourne, Melbourne, Australia
    J Clin Microbiol 47:3826-31. 2009
    ..Across these 45 studies, the association of endotoxemia with GN bacteremia is variable but consistent for different types of GN bacteremia...
  12. doi request reprint Profound effect of study design factors on ventilator-associated pneumonia incidence of prevention studies: benchmarking the literature experience
    James C Hurley
    School of Rural Health, University of Melbourne, Australia
    J Antimicrob Chemother 61:1154-61. 2008
    ..The objective here is to develop and validate a literature-derived benchmark against which these groups can be profiled...
  13. ncbi request reprint Inapparent outbreaks of ventilator-associated pneumonia: an ecologic analysis of prevention and cohort studies
    James C Hurley
    Infection Control Committees of St John of God Hospital and Ballarat Health Services, Ballarat, Victoria, Australia
    Infect Control Hosp Epidemiol 26:374-90. 2005
    ..To compare ventilator-associated pneumonia (VAP) rates and patterns of isolates across studies of antibiotic and non-antibiotic methods for preventing VAP...
  14. ncbi request reprint Endotoxemia and Gram-negative bacteremia as predictors of outcome in sepsis: a meta-analysis using ROC curves
    James C Hurley
    Division of Medicine, Ballarat Health Services, Ballarat, Victoria, Australia
    J Endotoxin Res 9:271-9. 2003
    ..The differing interpretations among published studies could be attributed to the variability in types of Gram-negative bacteremia observed...
  15. ncbi request reprint Mortality due to vancomycin-resistant enterococcal bacteremia versus vancomycin-susceptible enterococcal bacteremia: an ecological analysis
    James C Hurley
    Clin Infect Dis 41:1541-2. 2005
  16. ncbi request reprint Comparison of mortality associated with methicillin-susceptible and methicillin-resistant Staphylococcus aureus bacteremia: an ecological analysis
    James C Hurley
    Clin Infect Dis 37:866-8; author reply 868-9. 2003
  17. ncbi request reprint Risk of death from methicillin-resistant Staphylococcus aureus bacteraemia: a meta-analysis
    James C Hurley
    Med J Aust 176:188; author reply 189. 2002