Jesu Arockiaraj

Summary

Publications

  1. doi request reprint Crustin, a WAP domain containing antimicrobial peptide from freshwater prawn Macrobrachium rosenbergii: immune characterization
    Jesu Arockiaraj
    Department of Biotechnology, Faculty of Science and Humanities, SRM University, SRM Nagar, Kattankulathur, Chennai, Tamil Nadu, India
    Fish Shellfish Immunol 34:109-18. 2013
  2. doi request reprint Immune role of MrNFκBI-α, an IκB family member characterized in prawn M. rosenbergii
    Jesu Arockiaraj
    Department of Biotechnology, Faculty of Science and Humanities, SRM University, SRM Nagar, Kattankulathur 603203, Chennai, Tamil Nadu, India
    Fish Shellfish Immunol 33:619-25. 2012
  3. doi request reprint Molecular functions of chaperonin gene, containing tailless complex polypeptide 1 from Macrobrachium rosenbergii
    Jesu Arockiaraj
    Department of Biotechnology, Faculty of Science and Humanities, SRM University, SRM Nagar, Kattankulathur 603 203, Chennai, Tamil Nadu, India
    Gene 508:241-9. 2012
  4. doi request reprint An unconventional antimicrobial protein histone from freshwater prawn Macrobrachium rosenbergii: analysis of immune properties
    Jesu Arockiaraj
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, Chennai 603 203, Tamil Nadu, India Electronic address
    Fish Shellfish Immunol 35:1511-22. 2013
  5. doi request reprint Immunological role of C4 CC chemokine-1 from snakehead murrel Channa striatus
    Prasanth Bhatt
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, Chennai 603 203, Tamil Nadu, India
    Mol Immunol 57:292-301. 2014
  6. doi request reprint A prawn transglutaminase: molecular characterization and biochemical properties
    Jesu Arockiaraj
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, 603 203 Chennai, Tamil Nadu, India Electronic address
    Biochimie 95:2354-64. 2013
  7. doi request reprint Macrobrachium rosenbergii cathepsin L: molecular characterization and gene expression in response to viral and bacterial infections
    Jesu Arockiaraj
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, Chennai, Tamil Nadu 603 203, India
    Microbiol Res 168:569-79. 2013
  8. doi request reprint Fish lily type lectin-1 contains β-prism architecture: immunological characterization
    Abirami Arasu
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur 603 203, Chennai, Tamil Nadu, India Department of Microbiology, SRM Arts and Science College, Kattankulathur 603 203, Chennai, India
    Mol Immunol 56:497-506. 2013
  9. doi request reprint Molecular cloning, characterization and gene expression of murrel CXC chemokine receptor 3a against sodium nitrite acute toxicity and microbial pathogens
    Prasanth Bhatt
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, 603 203 Chennai, Tamil Nadu, India
    Fish Shellfish Immunol 39:245-53. 2014
  10. doi request reprint An anti-apoptotic B-cell lymphoma-2 (BCL-2) from Channa striatus: Sequence analysis and delayed and advanced gene expression in response to fungal, bacterial and poly I:C induction
    Jesu Arockiaraj
    Division of Fisheries Biotechnology and Molecular Biology, Research Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, Chennai 603203, Tamil Nadu, India Electronic address
    Mol Immunol 63:586-94. 2015

Collaborators

  • Ramasamy Harikrishnan
  • Venkatesh Kumaresan
  • Mukesh Kumar Chaurasia
  • Rajesh Palanisamy
  • Mukesh Pasupuleti
  • Prasanth Bhatt
  • Naif Abdullah Al-Dhabi
  • Annie J Gnanam
  • Mariadhas Valan Arasu
  • Abirami Arasu
  • Nagarajan Balachandran Dhayanithi
  • Kasi Marimuthu
  • Akila Sathyamoorthi
  • Suntharam Jawahar
  • Faizal Nizam
  • Gayathri Ravichandran
  • Chellam Balasundaram
  • Marimuthu Kasi
  • Muthukumaresan Kuppuswamy Thirumalai
  • Arpita Roy
  • Aziz Arshad
  • Mohamed Saiyad Musthafa
  • Preetham Elumalai
  • Krishnan Vasanth
  • Adil Nafar
  • Thipramalai Thankappan Ajith Kumar
  • MariadhasValan Arasu
  • Munuswamy Ramanujam Ganesh
  • Harikrishnan Ramaswamy
  • Suma Sanikommu
  • Muthukumaresan Kuppusamy Thirumalai
  • Nagaram Prabha

Detail Information

Publications31

  1. doi request reprint Crustin, a WAP domain containing antimicrobial peptide from freshwater prawn Macrobrachium rosenbergii: immune characterization
    Jesu Arockiaraj
    Department of Biotechnology, Faculty of Science and Humanities, SRM University, SRM Nagar, Kattankulathur, Chennai, Tamil Nadu, India
    Fish Shellfish Immunol 34:109-18. 2013
    ..These results suggest that MrCrs is a potential antimicrobial peptide, which is involved in the defense system of M. rosenbergii against viral and bacterial infections...
  2. doi request reprint Immune role of MrNFκBI-α, an IκB family member characterized in prawn M. rosenbergii
    Jesu Arockiaraj
    Department of Biotechnology, Faculty of Science and Humanities, SRM University, SRM Nagar, Kattankulathur 603203, Chennai, Tamil Nadu, India
    Fish Shellfish Immunol 33:619-25. 2012
    ..hydrophila and E. faecium infection. This result indicates an important role of MrNFκBI-α in M. rosenbergii immune system. This, however, remains to be verified by further studies...
  3. doi request reprint Molecular functions of chaperonin gene, containing tailless complex polypeptide 1 from Macrobrachium rosenbergii
    Jesu Arockiaraj
    Department of Biotechnology, Faculty of Science and Humanities, SRM University, SRM Nagar, Kattankulathur 603 203, Chennai, Tamil Nadu, India
    Gene 508:241-9. 2012
    ..These results suggest that MrChap is potentially involved in the immune responses against viral infection in M. rosenbergii. These findings indicate that the recombinant MrChap protein may be used in immunotherapeutic approaches...
  4. doi request reprint An unconventional antimicrobial protein histone from freshwater prawn Macrobrachium rosenbergii: analysis of immune properties
    Jesu Arockiaraj
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, Chennai 603 203, Tamil Nadu, India Electronic address
    Fish Shellfish Immunol 35:1511-22. 2013
    ..Hence, it is possible to suggest that the activity may be due to the direct defense role of histone or its N-terminal antimicrobial property. However, this remains to be verified by detailed investigations...
  5. doi request reprint Immunological role of C4 CC chemokine-1 from snakehead murrel Channa striatus
    Prasanth Bhatt
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, Chennai 603 203, Tamil Nadu, India
    Mol Immunol 57:292-301. 2014
    ..Moreover, the chemotaxis assay showed the capability of recombinant CsCC-Chem-1 protein which can induce the migration of spleen leukocytes in C. striatus. However, this remains to be verified further at molecular and proteomic level...
  6. doi request reprint A prawn transglutaminase: molecular characterization and biochemical properties
    Jesu Arockiaraj
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, 603 203 Chennai, Tamil Nadu, India Electronic address
    Biochimie 95:2354-64. 2013
    ..Overall, these results suggested that MrTGase is a major and functional TGase of M. rosenbergii for haemolymph coagulation and also in spread of infection...
  7. doi request reprint Macrobrachium rosenbergii cathepsin L: molecular characterization and gene expression in response to viral and bacterial infections
    Jesu Arockiaraj
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, Chennai, Tamil Nadu 603 203, India
    Microbiol Res 168:569-79. 2013
    ..Conclusively, the results of this study imply that MrCathL has high pH stability and is fascinating object for further research on the function of cathepsin L in prawn innate immune system. ..
  8. doi request reprint Fish lily type lectin-1 contains β-prism architecture: immunological characterization
    Abirami Arasu
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur 603 203, Chennai, Tamil Nadu, India Department of Microbiology, SRM Arts and Science College, Kattankulathur 603 203, Chennai, India
    Mol Immunol 56:497-506. 2013
    ..The overall results showed that CsLTL-1 is an important immune gene involved in the recognition and elimination of pathogens in murrels. ..
  9. doi request reprint Molecular cloning, characterization and gene expression of murrel CXC chemokine receptor 3a against sodium nitrite acute toxicity and microbial pathogens
    Prasanth Bhatt
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, 603 203 Chennai, Tamil Nadu, India
    Fish Shellfish Immunol 39:245-53. 2014
    ..However, further study is necessary to explore the striped murrel chemokine signaling pathways and their roles in defense system...
  10. doi request reprint An anti-apoptotic B-cell lymphoma-2 (BCL-2) from Channa striatus: Sequence analysis and delayed and advanced gene expression in response to fungal, bacterial and poly I:C induction
    Jesu Arockiaraj
    Division of Fisheries Biotechnology and Molecular Biology, Research Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, Chennai 603203, Tamil Nadu, India Electronic address
    Mol Immunol 63:586-94. 2015
    ..Overall, the CsBCL-2 mRNA transcription results indicate the potential involvement of CsBCL-2 in immune system of C. striatus. However, further research at proteomic level is necessary to examine these predictions. ..
  11. doi request reprint A murrel interferon regulatory factor-1: molecular characterization, gene expression and cell protection activity
    Jesu Arockiaraj
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, Chennai, 603 203, Tamil Nadu, India
    Mol Biol Rep 41:5299-309. 2014
    ..Overall, these results indicate the immune importance of IRF-1, however, the interferon signaling mechanism in murrels upon infection is yet to be studied at proteomic level...
  12. doi request reprint Molecular characterization of a novel proto-type antimicrobial protein galectin-1 from striped murrel
    Abirami Arasu
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur 603203, Chennai, Tamil Nadu, India Department of Microbiology, SRM Arts and Science College, Kattankulathur 603203, Chennai, Tamil Nadu, India
    Microbiol Res 169:824-34. 2014
    ..Interestingly, we observed no agglutination against Gram-positive bacteria. Overall, the study showed that CsGal-1 is an important immune gene involved in the recognition and elimination of pathogens in C. striatus...
  13. doi request reprint A cytosolic glutathione s-transferase, GST-theta from freshwater prawn Macrobrachium rosenbergii: molecular and biochemical properties
    Jesu Arockiaraj
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur 603 203, Chennai, Tamil Nadu, India Electronic address
    Gene 546:437-42. 2014
    ..Overall, the results suggest a potential role for M. rosenbergii GST-θ in detoxification and possibly conferring immune protection...
  14. doi request reprint A novel prophenoloxidase, hemocyanin encoded copper containing active enzyme from prawn: gene characterization
    Jesu Arockiaraj
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur 603 203, Chennai, Tamil Nadu, India
    Gene 524:139-51. 2013
    ..i. and then the activity started decreasing. Overall results indicate that MrProPO is very likely to participate in the acute response against pathogen entry in prawns...
  15. doi request reprint Multifunctional murrel caspase 1, 2, 3, 8 and 9: Conservation, uniqueness and their pathogen-induced expression pattern
    Venkatesh Kumaresan
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, 603 203, Chennai, Tamil Nadu, India
    Fish Shellfish Immunol 49:493-504. 2016
    ..Overall, the results suggested that the caspases in murrel are diverse in their structure and function. Here, we discuss the similarities and differences of five different murrel caspases. ..
  16. doi request reprint A prawn core histone 4: derivation of N- and C-terminal peptides and their antimicrobial properties, molecular characterization and mRNA transcription
    Mukesh Kumar Chaurasia
    Division of Fisheries Biotechnology and Molecular Biology, Research Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, Chennai 603203, Tamil Nadu, India
    Microbiol Res 170:78-86. 2015
    ..Among the two peptides used in this study, C-terminal peptide yielded better results than the N-terminal peptide. Therefore, C terminal peptide can be recommended for the development of an antimicrobial agent. ..
  17. doi request reprint A novel single-domain peptide, anti-LPS factor from prawn: synthesis of peptide, antimicrobial properties and complete molecular characterization
    Jesu Arockiaraj
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur 603 203, Chennai, Tamil Nadu, India Electronic address
    Peptides 53:79-88. 2014
    ..In summary, the comprehensive analysis of MrALF showed it to be an effective antimicrobial peptide and thus it plays a crucial role in the defense mechanism of M. rosenbergii...
  18. doi request reprint Fish chemokines 14, 20 and 25: A comparative statement on computational analysis and mRNA regulation upon pathogenic infection
    Jesu Arockiaraj
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, 603 203 Chennai, Tamil Nadu, India Electronic address
    Fish Shellfish Immunol 47:221-30. 2015
    ..However, extensive studies are required to determine the functional activities of CsCC-Chem14, CsCC-Chem20 and CsCC-Chem25 in vitro and in vivo to gain more knowledge at the molecular and proteomic levels...
  19. doi request reprint A novel antimicrobial peptide derived from fish goose type lysozyme disrupts the membrane of Salmonella enterica
    Venkatesh Kumaresan
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, 603 203 Chennai, Tamil Nadu, India
    Mol Immunol 68:421-33. 2015
    ..Conclusively, CsLyzG is a potential innate immune component and the identified antimicrobial peptide has great caliber to be used as an ecofriendly antibacterial substance in aquaculture. ..
  20. doi request reprint A novel murrel Channa striatus mitochondrial manganese superoxide dismutase: gene silencing, SOD activity, superoxide anion production and expression
    Jesu Arockiaraj
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, Chennai, 603 203, Tamil Nadu, India
    Fish Physiol Biochem 40:1937-55. 2014
    ..Overall, this study indicated the defense potentiality of CsmMnSOD; however, further research is necessary to explore its capability at protein level...
  21. doi request reprint Molecular profiles and pathogen-induced transcriptional responses of prawn B cell lymphoma-2 related ovarian killer protein (BOK)
    Mukesh Kumar Chaurasia
    Division of Fisheries Biotechnology and Molecular Biology, Research Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, 603 203, Chennai, Tamil Nadu, India
    Fish Shellfish Immunol 45:598-607. 2015
    ..This is the first study that emphasizes the importance of BOK during bacterial and viral infection in crustacean...
  22. doi request reprint Functional roles and gene regulation of tumor necrosis factor receptor 1 in freshwater striped murrel
    Rajesh Palanisamy
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur 603 203, Chennai, Tamil Nadu, India
    Mol Immunol 66:240-52. 2015
    ..Overall, the study showed that the CsTNFR1 plays an important role in the pathogen-induced inflammatory process of striped murrel...
  23. doi request reprint Macrobrachium rosenbergii mannose binding lectin: synthesis of MrMBL-N20 and MrMBL-C16 peptides and their antimicrobial characterization, bioinformatics and relative gene expression analysis
    Jesu Arockiaraj
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, 603 203 Chennai, Tamil Nadu, India Electronic address
    Fish Shellfish Immunol 43:364-74. 2015
    ..Moreover, MrMBL derived MrMBL-N20 and MrMBL-C16 peptides are important antimicrobial peptides for the recognition and eradication of viral and bacterial pathogens. ..
  24. doi request reprint Molecular importance of prawn large heat shock proteins 60, 70 and 90
    Mukesh Kumar Chaurasia
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, 603 203, Chennai, Tamil Nadu, India
    Fish Shellfish Immunol 48:228-38. 2016
    ..The study indicated the potentiality of these molecules, thereby protecting cells against pathogens as well as severe cellular and environmental stresses in crustaceans. ..
  25. doi request reprint Molecular and functional roles of 6C CC chemokine 19 in defense system of striped murrel Channa striatus
    Jesu Arockiaraj
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, 603 203 Chennai, Tamil Nadu, India Electronic address
    Fish Shellfish Immunol 45:817-27. 2015
    ..However, further research is necessary to understand the potential of 6C CC chemokine 19 of C. striatus, particularly their regulatory ability on different cellular components in the defense system...
  26. doi request reprint Comparative analysis of CsCu/ZnSOD defense role by molecular characterization: gene expression-enzyme activity-protein level
    Venkatesh Kumaresan
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, 603 203, Chennai, Tamil Nadu, India
    Gene 564:53-62. 2015
    ..Overall, the findings demonstrated that the CsCu/ZnSOD plays a critical role in the antioxidant system especially in the liver during oxidative stress caused by fungus and bacteria...
  27. doi request reprint An upstream initiator caspase 10 of snakehead murrel Channa striatus, containing DED, p20 and p10 subunits: molecular cloning, gene expression and proteolytic activity
    Jesu Arockiaraj
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, Chennai, Tamil Nadu, India
    Fish Shellfish Immunol 34:505-13. 2013
    ..invadans and A. hydrophila stimulation were analyzed by caspase 10 activity assay kit. All these results showed that CsCasp10 are participated in immunity of C. striatus against A. invadans and A. hydrophila infection...
  28. doi request reprint Dietary supplementation of Zeolite on growth performance, immunological role, and disease resistance in Channa striatus against Aphanomyces invadans
    Suntharam Jawahar
    P G and Research Department of Biotechnology, Bharath College of Science and Management, Thanjavur, Tamil Nadu, India
    Fish Shellfish Immunol 51:161-9. 2016
    ..The present study suggests that dietary supplementation with 4% or 6% Zeolite significantly increase growth performance, hemato-biochemical changes, immunological response, and disease resistance in C. striatus against A. invadans. ..
  29. doi request reprint A potential Kazal-type serine protease inhibitor involves in kinetics of protease inhibition and bacteriostatic activity
    Venkatesh Kumaresan
    Division of Fisheries Biotechnology and Molecular Biology, Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur, 603 203 Chennai, Tamil Nadu, India
    Fish Shellfish Immunol 42:430-8. 2015
    ..hydrophila at 20 μM and Gram-positive bacteria Bacillus subtilis at the MIC50 of 15 μM. Overall, the study indicated that the CsKSPI was a potential trypsin inhibitor which involves in antimicrobial activity...
  30. doi request reprint A simple, robust enzymatic-based high-throughput screening method for antimicrobial peptides discovery against Escherichia coli
    Muthukumaresan Kuppuswamy Thirumalai
    SRM Research Institute, SRM University, Chennai, Tamil Nadu, India
    J Pept Sci 20:341-8. 2014
    ..Even though this method can be applied to other strain, our experience shows that one has to be careful especially when the pigments or metabolites present in the bacteria have the same wavelength absorbance...
  31. doi request reprint Dietary supplementation of Avicennia marina extract on immune protection and disease resistance in Amphiprion sebae against Vibrio alginolyticus
    Nagarajan Balachandran Dhayanithi
    Centre of Advanced Study in Marine Biology, Annamalai University, Parangipettai 608 502, Tamil Nadu, India
    Fish Shellfish Immunol 45:52-8. 2015
    ..This study reports that in clownfish challenged with V. alginolyticus, dietary administration of the 1% or 4% of A. marina extract improved the immune status and survival rate...